Cited by 332Schizophrenia research and treatmentPsychotherapy Techniques and ApplicationsBipolar Disorder and Treatment

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Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial

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Morrison, A. P., French, P., Stewart, S. L. K., Birchwood, M., Fowler, D., Gumley, A. I., Jones, P. B., Bentall, R. P., Lewis, S. W., Murray, G. K., Patterson, P., Brunet, K., Conroy, J., Parker, S., Reilly, T., Byrne, R., Davies, L. M., Dunn, G.·2012·BMJ

DOI 10.1136/bmj.e2233PMC PMC3320714

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Abstract

OBJECTIVE: To determine whether cognitive therapy is effective in preventing the worsening of emerging psychotic symptoms experienced by help seeking young people deemed to be at risk for serious conditions such as schizophrenia. DESIGN: Multisite single blind randomised controlled trial. SETTING: Diverse services at five UK sites. PARTICIPANTS: 288 participants aged 14-35 years (mean 20.74, SD 4.34 years) at high risk of psychosis: 144 were assigned to cognitive therapy plus monitoring of mental state and 144 to monitoring of mental state only. Participants were followed-up for a minimum of 12 months and a maximum of 24 months. INTERVENTION: Cognitive therapy (up to 26 (mean 9.1) sessions over six months) plus monitoring of mental state compared with monitoring of mental state only. MAIN OUTCOME MEASURES: Primary outcome was scores on the comprehensive assessment of at risk mental states (CAARMS), which provides a dichotomous transition to psychosis score and ordinal scores for severity of psychotic symptoms and distress. Secondary outcomes included emotional dysfunction and quality of life. RESULTS: Transition to psychosis based on intention to treat was analysed using discrete time survival models. Overall, the prevalence of transition was lower than expected (23/288; 8%), with no significant difference between the two groups (proportional odds ratio 0.73, 95% confidence interval 0.32 to 1.68). Changes in severity of symptoms and distress, as well as secondary outcomes, were analysed using random effects regression (analysis of covariance) adjusted for site and baseline symptoms. Distress from psychotic symptoms did not differ (estimated difference at 12 months -3.00, 95% confidence interval -6.95 to 0.94) but their severity was significantly reduced in the group assigned to cognitive therapy (estimated between group effect size at 12 months -3.67, -6.71 to -0.64, P=0.018). CONCLUSIONS: Cognitive therapy plus monitoring did not significantly reduce transition to psychosis or symptom related distress but reduced the severity of psychotic symptoms in young people at high risk. Most participants in both groups improved over time. The results have important implications for the at risk mental state concept. TRIAL REGISTRATION: Current Controlled Trials ISRCTN56283883.

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Hausman, J. A. (1978) · Econometrica · doi:10.2307/1913827 · Cited by 18,820
Statistical Analysis With Missing Data
Lahiff, M., Little, R. J. A., & Rubin, D. B. (1989) · Journal of the American Statistical Association · doi:10.2307/2289883 · Cited by 17,385
The Structured Clinical Interview for DSM-III-R (SCID): I: History, Rationale, and Description
Spitzer, R. L. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820080032005 · Cited by 4,336
Development and validation of measures of social phobia scrutiny fear and social interaction anxiety11Editor’s note: This article was written before the development of some contemporary measures of social phobia, such as the Social Phobia and Anxiety Inventory (Turner et al., 1989). We have invited this article for publication because of the growing interest in the scales described therein. S.T.
Mattick, R. P., & Clarke, J. C. (1998) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(97)10031-6 · Cited by 3,367
A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder
van Os, J., Linscott, R. J., Myin-Germeys, I., Delespaul, P., & Krabbendam, L. (2009) · Psychological Medicine · doi:10.1017/s0033291708003814 · Cited by 2,343
Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States
Yung, A. R., Yung, A. R., Yuen, H. P., McGorry, P. D., Phillips, L., Kelly, D., Dell’Olio, M., Francey, S. M., Cosgrave, E., Killackey, E. J., et al. (2005) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2005.01714.x · Cited by 2,268
Applied Multivariate Data Analysis
Jobson, J. D. (1992) · Springer texts in statistics · doi:10.1007/978-1-4612-0921-8 · Cited by 1,851
Prodromal Assessment With the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms: Predictive Validity, Interrater Reliability, and Training to Reliability
Miller, T. J., McGlashan, T. H., Rosen, J. L., Cadenhead, K. S., Ventura, J., McFarlane, W. R., Perkins, D. O., Pearlson, G. D., & Woods, S. W. (2003) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a007040 · Cited by 1,800
Prediction of Psychosis in Youth at High Clinical Risk: A Multisite Longitudinal Study in North America
Cannon, T. D., Cadenhead, K., Cornblatt, B., Woods, S. W., Addington, J., Walker, E., Seidman, L. J., Perkins, D., Tsuang, M., McGlashan, T., et al. (2008) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2007.3 · Cited by 1,269
Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group
Yung, A. R., Phillips, L. J., Yuen, H. P., Francey, S. M., McFarlane, C. A., Hallgren, M., & McGorry, P. D. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00167-6 · Cited by 1,136
Application and Results of the Manchester Short Assessment of Quality of Life (Mansa)
Priebe, S., Huxley, P., Knight, S., & Evans, S. (1999) · International Journal of Social Psychiatry · doi:10.1177/002076409904500102 · Cited by 1,071
Randomized Controlled Trial of Interventions Designed to Reduce the Risk of Progression to First-Episode Psychosis in a Clinical Sample With Subthreshold Symptoms
McGorry, P. D., Yung, A. R., Phillips, L. J., Yuen, H. P., Francey, S., Cosgrave, E. M., Germano, D., Bravin, J., McDonald, T., Blair, A., et al. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.10.921 · Cited by 1,056
. Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor.
Wykes, T., Steel, C., Everitt, B., & Tarrier, N. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm114 · Cited by 1,029
Long-term Antipsychotic Treatment and Brain Volumes
Ho, B., Andreasen, N., Ziebell, S., Pierson, R., & Magnotta, V. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.199 · Cited by 952
Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions
McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01860.x · Cited by 919
Long-Chain ω-3 Fatty Acids for Indicated Prevention of Psychotic Disorders: A Randomized, Placebo-Controlled Trial
Amminger, G. P., Schäfer, M. R., Papageorgiou, K., Klier, C. M., Cotton, S. M., Harrigan, S. M., Mackinnon, A., McGorry, P. D., & Berger, G. E. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.192 · Cited by 896
Prospective Diagnosis of the Initial Prodrome for Schizophrenia Based on the Structured Interview for Prodromal Syndromes: Preliminary Evidence of Interrater Reliability and Predictive Validity
Miller, T. J., McGlashan, T. H., Rosen, J. L., Somjee, L., Markovich, P. J., Stein, K., & Woods, S. W. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.5.863 · Cited by 872
Predicting Psychosis: Meta-analysis of Transition Outcomes in Individuals at High Clinical Risk
Buckley, P. (2013) · Yearbook of Psychiatry and Applied Mental Health · doi:10.1016/j.ypsy.2012.07.042 · Cited by 774
Monitoring and Care of Young People at Incipient Risk of Psychosis
Yung, A. R., McGorry, P. D., McFarlane, C. A., Jackson, H. J., Patton, G. C., & Rakkar, A. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.2.283 · Cited by 773
Elevated Striatal Dopamine Function Linked to Prodromal Signs of Schizophrenia
Howes, O. D., Montgomery, A. J., Asselin, M.-C., Murray, R. M., Valli, I., Tabraham, P., Bramon-Bosch, E., Valmaggia, L., Johns, L., Broome, M., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.514 · Cited by 744
Cognitive therapy for the prevention of psychosis in people at ultra-high risk: Randomised controlled trial
Morrison, A. P., French, P., Walford, L., Lewis, S. W., Kilcommons, A., Green, J., Parker, S., & Bentall, R. P. (2004) · British Journal of Psychiatry · doi:10.1192/bjp.185.4.291 · Cited by 740
Self-citation
Screening for major depression disorders in medical inpatients with the Beck Depression Inventory for Primary Care
Beck, A. T., Guth, D., Steer, R. A., & Ball, R. (1997) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(97)00025-9 · Cited by 733
A Randomized Controlled Trial of Cognitive-Behavioral Therapy for Persistent Symptoms in Schizophrenia Resistant to Medication
Sensky, T., Turkington, D., Kingdon, D., Scott, J. L., Scott, J., Siddle, R., O'Carroll, M., & Barnes, T. R. E. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.2.165 · Cited by 691
A comparison of cognitive therapy, applied relaxation and imipramine in the treatment of panic disorder
Clark, D. M., Salkovskis, P. M., Hackmann, A., Middleton, H., Anastasiades, P., & Gelder, M. (1994) · British Journal of Psychiatry · doi:10.1192/bjp.164.6.759 · Cited by 673
The interpretation of intrusions in psychosis: an integrative cognitive approach to hallucinations and delusions
Morrison, A. P. (2001) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465801003010 · Cited by 673
Self-citation
Prediction of Psychosis in Adolescents and Young Adults at High Risk: Results From the Prospective European Prediction of Psychosis Study
Ruhrmann, S., Schultze-Lutter, F., Salokangas, R. K. R., Heinimaa, M., Linszen, D., Dingemans, P., Birchwood, M., Patterson, P., Juckel, G., Heinz, A., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.206 · Cited by 632
Self-citation
The revised cognitive therapy scale (CTS-R): psychometric properties.
Blackburn, I.-M., James, I. A., Milne, D. L., Baker, C., Standart, S., Garland, A., & Reichelt, F. K. (2001) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465801004040 · Cited by 568
Randomized, Double-Blind Trial of Olanzapine Versus Placebo in Patients Prodromally Symptomatic for Psychosis
McGlashan, T. H., Zipursky, R. B., Perkins, D., Addington, J., Miller, T., Woods, S. W., A. Hawkins, K., E. Hoffman, R., Preda, A., Epstein, I., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.5.790 · Cited by 556
The effects of psychotherapy for adult depression are overestimated: a meta-analysis of study quality and effect size
Cuijpers, P., van Straten, A., Bohlmeijer, E., Hollon, S. D., & Andersson, G. (2010) · Psychological Medicine · doi:10.1017/s0033291709006114 · Cited by 533
Evidence That Onset of Clinical Psychosis Is an Outcome of Progressively More Persistent Subclinical Psychotic Experiences: An 8-Year Cohort Study
Dominguez, M.-D.-G., Wichers, M., Lieb, R., Wïttchen, H., & van Os, J. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp022 · Cited by 487
At Clinical High Risk for Psychosis: Outcome for Nonconverters
Addington, J., Cornblatt, B. A., Cadenhead, K. S., Cannon, T. D., McGlashan, T. H., Perkins, D. O., Seidman, L. J., Tsuang, M. T., Walker, E. F., Woods, S. W., et al. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10081191 · Cited by 477
Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies
Kelleher, I., Keeley, H. S., Corcoran, P. E., Lynch, F., Fitzpatrick, C., Devlin, N. M., Molloy, C., Roddy, S., Clarke, M. C., Harley, M., et al. (2012) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.111.101543 · Cited by 443
Randomised controlled trial of intensive cognitive behaviour therapy for patients with chronic schizophrenia
Tarrier, N., Yusupoff, L., Kinney, C., McCarthy, E., Gledhill, A., Haddock, G., & Morris, J. (1998) · BMJ · doi:10.1136/bmj.317.7154.303 · Cited by 442
Declining Transition Rate in Ultra High Risk (Prodromal) Services: Dilution or Reduction of Risk?
Yung, A. R., Yuen, H. P., Berger, G. E., Francey, S. M., Hung, T.-C., Nelson, B., Phillips, L., & McGorry, P. D. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm015 · Cited by 422
Do subthreshold psychotic experiences predict clinical outcomes in unselected non-help-seeking population-based samples? A systematic review and meta-analysis, enriched with new results
Kaymaz, N., Drukker, M., Lieb, R., Wittchen, H.-U., Werbeloff, N., Weiser, M., Lataster, T., & van Os, J. (2012) · Psychological Medicine · doi:10.1017/s0033291711002911 · Cited by 420
International clinical practice guidelines for early psychosis
INTERNATIONAL EARLY PSYCHOSIS ASSOCIATION WRITING GROUP (2005) · The British Journal of Psychiatry · doi:10.1192/bjp.187.48.s120 · Cited by 334
Non-pharmacological management of antipsychotic-induced weight gain: Systematic review and meta-analysis of randomised controlled trials
Álvarez‐Jiménez, M., Hetrick, S. E., González‐Blanch, C., Gleeson, J., & McGorry, P. D. (2008) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.107.042853 · Cited by 315
A systematic review of the effects of antipsychotic drugs on brain volume
Moncrieff, J., & Leo, J. (2010) · Psychological Medicine · doi:10.1017/s0033291709992297 · Cited by 312
Schizophrenia Proneness Instrument - Adult version (SPI-A)
Medina-Pradas, C., & Neus Barrantes-vidal, A. (2012) · Cited by 289
Systematic Review of Early Cardiometabolic Outcomes of the First Treated Episode of Psychosis
Foley, D. L., & Morley, K. I. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.2 · Cited by 283
Psychotic-Like Experiences in Major Depression and Anxiety Disorders: A Population-Based Survey in Young Adults
Varghese, D., Scott, J. G., Welham, J., Bor, W., Najman, J. M., O'Callaghan, M. J., Williams, G. M., & McGrath, J. J. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp083 · Cited by 271
Psychotic-like experiences in nonpsychotic help-seekers: associations with distress, depression, and disability
Yung, A. R., Buckby, J. A., Cotton, S. M., Cosgrave, E. M., Killackey, E. J., Stanford, C., Godfrey, K., & McGorry, P. D. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbj018 · Cited by 264
Discriminant validity of the Social Phobia and Anxiety Inventory (SPAI), the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS)
Peters, L. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(99)00131-x · Cited by 252
A strategy for modelling the effect of a continuous covariate in medicine and epidemiology.
Royston, P. (2000) · Statistics in Medicine · doi:10.1002/1097-0258(20000730)19:14 · Cited by 234
Efficacy of Using Cognitive Status in Predicting Psychosis: A 7-Year Follow-Up
Riecher‐Rössler, A., Pflueger, M. O., Aston, J., Borgwardt, S., Brewer, W. J., Gschwandtner, U., & Stieglitz, R. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.020 · Cited by 229
Three-Year Follow-up of a Randomized Controlled Trial of Cognitive Therapy for the Prevention of Psychosis in People at Ultrahigh Risk
Morrison, A. P., French, P., Parker, S., Roberts, M., Stevens, H., Bentall, R. P., & Lewis, S. W. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbl042 · Cited by 228
Self-citation
A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis
Addington, J., Epstein, I., Liu, L., French, P., Boydell, K. M., & Zipursky, R. B. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2010.10.015 · Cited by 226
Self-citation
Preventing progression to first-episode psychosis in early initial prodromal states
Bechdolf, A., Wagner, M., Ruhrmann, S., Harrigan, S., Putzfeld, V., Pukrop, R., Brockhaus-Dumke, A., Berning, J., Janssen, B., Decker, P., et al. (2012) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.066357 · Cited by 224
Introduction: the extended psychosis phenotype—relationship with schizophrenia and with ultrahigh risk status for psychosis
van Os, J., & Linscott, R. J. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr188 · Cited by 213
Alterations in White Matter Evident Before the Onset of Psychosis
Carletti, F., Woolley, J. B., Bhattacharyya, S., Pérez‐Iglesias, R., Fusar‐Poli, P., Valmaggia, L., Broome, M. R., Bramon, E., Johns, L., Giampietro, V., et al. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs053 · Cited by 212
Baseline differences in clinical symptomatology between ultra high risk subjects with and without a transition to psychosis
Velthorst, E., Nieman, D. H., Becker, H. E., van de Fliert, R., Dingemans, P. M. A. J., Klaassen, R. M. C., de Haan, L., van Amelsvoort, T., & LINSZEN, D. H. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.02.002 · Cited by 208
What causes the onset of psychosis?
Broome, M. R., Woolley, J. B., Tabraham, P., Johns, L. C., Bramon, E., Murray, G. K., Pariante, C., McGuire, P. K., & Murray, R. M. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.02.007 · Cited by 207
Self-citation
Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis
Fusar-Poli, P., Howes, O. D., Allen, P., Broome, M., Valli, I., Asselin, M.-C., Montgomery, A. J., Grasby, P. M., & McGuire, P. (2011) · Molecular Psychiatry · doi:10.1038/mp.2009.108 · Cited by 207
Outreach and support in south London (OASIS): implementation of a clinical service for prodromal psychosis and the at risk mental state
Broome, M. R., Woolley, J. B., Johns, L., Valmaggia, L., Tabraham, P., Gafoor, R., Bramon, E., & McGuire, P. K. (2005) · European Psychiatry · doi:10.1016/j.eurpsy.2005.03.001 · Cited by 192
Affective dysregulation and reality distortion: a 10-year prospective study of their association and clinical relevance
van Rossum, I., Dominguez, M.-D.-G., Lieb, R., Wittchen, H.-U., & van Os, J. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp101 · Cited by 170
Randomized, Double-Blind Trial of Olanzapine Versus Placebo in Patients Prodromally Symptomatic for Psychosis
McGlashan, T. H. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.5.790 · Cited by 160
Is there a continuum of psychotic experiences in the general population?
van Os, J. (2003) · Epidemiology and Psychiatric Sciences · doi:10.1017/s1121189x00003067 · Cited by 155
Ultra high-risk state for psychosis and non-transition: A systematic review
Simon, A. E., Velthorst, E., Nieman, D. H., LINSZEN, D. H., Umbricht, D., & de Haan, L. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.07.002 · Cited by 155
Neural correlates of executive function and working memory in the ‘at-risk mental state’
Broome, M. R., Matthíasson, P., Fusar‐Poli, P., Woolley, J. B., Johns, L., Tabraham, P., Bramon, E., Valmaggia, L., Williams, S., Brammer, M. J., et al. (2008) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.107.046789 · Cited by 153
Reduced mismatch negativity predates the onset of psychosis
Shaikh, M., Valmaggia, L., Broome, M. R., Dutt, A., Lappin, J., Day, F., Woolley, J., Tabraham, P., Walshe, M., Johns, L., et al. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.09.022 · Cited by 150
Randomized Controlled Trial of Interventions for Young People at Ultra High Risk for Psychosis
Yung, A. R., Phillips, L., Nelson, B., Francey, S. M., PanYuen, H., Simmons, M. B., Ross, M., Kelly, D., Baker, K., Amminger, G. P., et al. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04979ora · Cited by 146
A randomised controlled trial of a worry intervention for individuals with persistent persecutory delusions
Foster, C., Startup, H. M., Potts, L. C., & Freeman, D. H. (2009) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2009.09.001 · Cited by 139
Medium term follow-up of a randomized controlled trial of interventions for young people at ultra high risk of psychosis
Phillips, L., McGorry, P. D., Yuen, H. P., WARD, J., DONOVAN, K., Kelly, D. J., Francey, S., & Yung, A. R. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.05.018 · Cited by 129
Self-report of attenuated psychotic experiences in a college population
Loewy, R. L., Johnson, J. K., & Cannon, T. D. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.02.010 · Cited by 129
Transition to Psychosis Associated With Prefrontal and Subcortical Dysfunction in Ultra High-Risk Individuals
Allen, P., Luigjes, J., Howes, O. D., Egerton, A., Hirao, K., Valli, I., Kambeitz, J., Fusar-Poli, P., Broome, M., & McGuire, P. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr194 · Cited by 129
Acute D2 receptor blockade induces rapid, reversible remodeling in human cortical-striatal circuits
Tost, H., Braus, D. F., Hakimi, S., Ruf, M., Vollmert, C., Höhn, F., & Meyer‐Lindenberg, A. (2010) · Nature Neuroscience · doi:10.1038/nn.2572 · Cited by 127
Randomised controlled trial of early detection and cognitive therapy for preventing transition to psychosis in high-risk individuals
Morrison, A., Bentall, R., French, P., Walford, L., Kilcommons, A., Knight, A., Kreutz, M., & Lewis, S. (2002) · British Journal of Psychiatry · doi:10.1192/bjp.181.43.s78 · Cited by 126
Self-citation
Early Detection and Cognitive Therapy for People at High Risk of Developing Psychosis: A Treatment Approach
French, P., & Morrison, A. P. (2004) · Thammasat University Digital Collections · doi:10.1002/9780470713259 · Cited by 97
Self-citation
Mapping the onset of psychosis: the comprehensive assessment of at risk mental states (CAARMS)
Yung, A. R., Yuen, H. P., Phillips, L. J., Francey, S., & McGorry, P. D. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(03)80090-7 · Cited by 84
Toward a world consensus on prevention of schizophrenia
Van Os, J., & Delespaul, P. (2005) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2005.7.1/jvanos · Cited by 75
Early detection and intervention evaluation for people at high-risk of psychosis-2 (EDIE-2): trial rationale, design and baseline characteristics: Early detection and intervention trial
Morrison, A. P., Stewart, S. L. K., French, P., Bentall, R. P., Birchwood, M., Byrne, R., Davies, L. M., Fowler, D., Gumley, A. I., Jones, P. B., et al. (2011) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2010.00254.x · Cited by 72
Self-citation
Early Intervention in Psychotic Relapse: Cognitive Approaches to Detection and Management
Birchwood, M. J. (1995) · Behaviour Change · doi:10.1017/s0813483900004344 · Cited by 63
Self-citation
Should attenuated psychosis syndrome be included in DSM-5?
Fusar‐Poli, P., & Yung, A. R. (2012) · The Lancet · doi:10.1016/s0140-6736(11)61507-9 · Cited by 62
Estimating dose-response effects in psychological treatment trials: the role of instrumental variables
Maracy, M. R., & Dunn, G. (2008) · Statistical Methods in Medical Research · doi:10.1177/0962280208097243 · Cited by 58
Self-citation
Prefrontal Function at Presentation Directly Related to Clinical Outcome in People at Ultrahigh Risk of Psychosis
Fusar‐Poli, P., Broome, M. R., Matthíasson, P., Woolley, J. B., Mechelli, A., Johns, L., Tabraham, P., Bramon, E., Valmaggia, L., Williams, S., et al. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp074 · Cited by 56
Neural correlates of visuospatial working memory in the ‘at-risk mental state’
Broome, M. R., Fusar‐Poli, P., Matthíasson, P., Woolley, J. B., Valmaggia, L., Johns, L., Tabraham, P., Bramon, E., Williams, S., Brammer, M. J., et al. (2010) · Psychological Medicine · doi:10.1017/s0033291710000280 · Cited by 42
Prediction of Psychosis in Adolescents and Young Adults at High Risk: Results From the Prospective European Prediction of Psychosis Study
Mack, A. H. (2011) · Yearbook of Psychiatry and Applied Mental Health · doi:10.1016/j.ypsy.2010.10.082 · Cited by 34
Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study
Ruhrmann, S., Schultze-Lutter, F., Salokangas, R. K. R., Heinimaa, M., LINSZEN, D. H., Dingemans, P. M. A. J., Birchwood, M. J., Patterson, P., Juckel, G., Heinz, A., et al. (2010) · Bern Open Repository and Information System (University of Bern) · Cited by 29
Self-citation
Delusional ideation, manic symptomatology and working memory in a cohort at clinical high-risk for psychosis: A longitudinal study
Broome, M. R., Day, F., Valli, I., Valmaggia, L., Johns, L., Howes, O. D., Garety, P. A., & McGuire, P. K. (2010) · European Psychiatry · doi:10.1016/j.eurpsy.2010.07.008 · Cited by 25
Philosophical Issues in the Prodromal Phase of Psychosis
Broome, M. R., & Fusar‐Poli, P. (2012) · Current Pharmaceutical Design · doi:10.2174/138161212799316190 · Cited by 13
[No Title]
Vergouwen, A. C. M., & Bakker, A. (2002) · The British Journal of Psychiatry · doi:10.1192/bjp.181.1.78-a · Cited by 13
The PsyGrid Experience
Ainsworth, J., & Harper, R. A. (2007) · International Journal of Healthcare Information Systems and Informatics · doi:10.4018/jhisi.2007040101 · Cited by 12
DSM‐5 and the ‘Psychosis Risk Syndrome’: Whose best interests would it serve?
Morrison, A. P., Byrne, R. E., & Bentall, R. P. (2010) · Psychosis · doi:10.1080/17522431003759982 · Cited by 11
Self-citation
ECONOMIC IMPACT OF EARLY INTERVENTION IN PEOPLE AT HIGH RISK OF PSYCHOSIS
Valmaggia, L., McCrone, P., Knapp, M. R. J., Broome, M. R., Power, P., & McGuire, P. K. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.02.484 · Cited by 8
Randomized controlled trial of interventions for young people at ultra high risk for psychosis: 6-Month analysis
(13100928), A. Y., (14448537), L. P., (7742435), B. N., (14450370), S. F., (13453860), H. P., (14537771), M. S., (14461491), M. R., (9854699), D. K., (12976641), K. B., (10229753), G. A., et al. (2024) · Figshare · Cited by 7
Patient adherence with antidepressant treatment
Lawton-Smith, S. H. (2002) · The British Journal of Psychiatry · doi:10.1192/bjp.181.1.78 · Cited by 6
International Early Psychosis Association
Addington, J. (2012) · Early Intervention in Psychiatry · doi:10.1111/eip.12006 · Cited by 6
Therapist treatment adherence in CBT for people at ultra-high risk for psychosis: Development of a new rating scale.
Bell, K. M., Startup, M., French, P., Morrison, A. P., Bucci, S., & Fowler, D. G. (2008) · Research Explorer (The University of Manchester) · Cited by 5
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[10]Cognitive behaviour therapy for acute schizophrenia: a controlled trial. British Psychological Society Annual Conference; 1994; Brighton, UK.

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Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide
Hoffmann, T. C., Glasziou, P. P., Boutron, I., Milne, R., Perera, R., Moher, D., Altman, D. G., Barbour, V., Macdonald, H., Johnston, M., et al. (2014) · BMJ · doi:10.1136/bmj.g1687 · Cited by 10,548
Risk of Mental Illness in Offspring of Parents With Schizophrenia, Bipolar Disorder, and Major Depressive Disorder: A Meta-Analysis of Family High-Risk Studies
Rasic, D., Hajek, T., Alda, M., & Uher, R. (2014) · Schizophrenia Bulletin · doi:10.1093/schbul/sbt114 · Cited by 758
The Lancet Psychiatry Commission on psychological treatments research in tomorrow's science
Holmes, E. A., Ghaderi, A., Harmer, C. J., Ramchandani, P. G., Cuijpers, P., Morrison, A. P., Roiser, J. P., Bockting, C. L. H., O'Connor, R. C., Shafran, R., et al. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(17)30513-8 · Cited by 624
Self-citation
Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated recommendations from the British Association for Psychopharmacology
Barnes, T. R. E., Drake, R., Paton, C., Cooper, S. J., Deakin, J. F. W., Ferrier, I. N., Gregory, C. J., Haddad, P. M., Howes, O. D., Jones, I. R., et al. (2019) · Journal of Psychopharmacology · doi:10.1177/0269881119889296 · Cited by 615
Self-citation
EPA guidance on the early intervention in clinical high risk states of psychoses
Schmidt, S. J., Schultze-Lutter, F., Schimmelmann, B. G., Maric, N. P., Salokangas, R. K. R., Riecher-Rössler, A., van der Gaag, M., Meneghelli, A., Nordentoft, M., Marshall, M., et al. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2015.01.013 · Cited by 585
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Authors: Morrison, A. P., French, P., Stewart, S. L. K., Birchwood, M., Fowler, D., Gumley, A. I., Jones, P. B., Bentall, R. P., Lewis, S. W., Murray, G. K., Patterson, P., Brunet, K., Conroy, J., Parker, S., Reilly, T., Byrne, R., Davies, L. M., & Dunn, G.
Affiliations: Greater Manchester Mental Health NHS Foundation Trust (GB)
University of Manchester (GB)
University of Birmingham (GB)
University of East Anglia (GB)
University of Glasgow (GB)
University of Cambridge (GB)
University of Liverpool (GB)
Birmingham and Solihull Mental Health NHS Foundation Trust (GB)
Cambridgeshire and Peterborough NHS Foundation Trust (GB)
Corresponding author: Morrison, A. P.
ORCID: Morrison, A. P.
French, P.
Stewart, S. L. K.
Birchwood, M.
Fowler, D.
Gumley, A. I.
Jones, P. B.
Bentall, R. P.
Lewis, S. W.
Murray, G. K.
Patterson, P.
Parker, S.
Byrne, R.
Davies, L. M.
Dunn, G.
Venue: BMJ
Publisher: BMJ
Published: 2012-04-05
Volume: 344
Issue: apr05 1
Pages: e2233-e2233
ISSN: 1756-1833 (ISSN-L)
DOI: 10.1136/bmj.e2233
PMC: PMC3320714
OpenAlex: W2095692398
Cited by: 332
References: 89
Citations by year: 2026: 3 · 2025: 8 · 2024: 11 · 2023: 15 · 2022: 14 · 2021: 21 · 2020: 23 · 2019: 47 · 2018: 27 · 2017: 25 · 2016: 21 · 2015: 29 · 2014: 19 · 2013: 45 · 2012: 23
FWCI: 26.41
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
Locations: BMJ (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
PubMed Central (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
Research Explorer (The University of Manchester) (publishedVersion)
edoc (University of Basel) (acceptedVersion, other-oa)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion)
Figshare (submittedVersion, cc-by)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
University of Warwick (cc-by)
Funders: National Institute for Health and Care Research
Medical Research Council (G0500264)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords: psychosis prevention, clinical high risk for psychosis, cognitive therapy, transition to psychosis, youth, mental state monitoring, psychotic symptom severity, distress, schizophrenia, early intervention
MeSH terms: Adolescent, Adult, Mental Disorders, Humans, Psychotic Disorders, Cognitive Behavioral Therapy, Single-Blind Method, Treatment Outcome, Early Diagnosis, Young Adult

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Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial

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