Cited by 1,812Meta-analysis and systematic reviewsDelphi Technique in ResearchClinical practice guidelines implementation

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis

Open access

Puhan, M. A., Schunemann, H. J., Murad, M. H., Li, T., Brignardello-Petersen, R., Singh, J. A., Kessels, A. G., Guyatt, G. H., for the GRADE Working Group·2014·BMJ

DOI 10.1136/bmj.g5630

Open this paper in CoChat — free account Open PDF

Abstract

Network meta-analysis (NMA), combining direct and indirect comparisons, is increasingly being used to examine the comparative effectiveness of medical interventions. Minimal guidance exists on how to rate the quality of evidence supporting treatment effect estimates obtained from NMA. We present a four-step approach to rate the quality of evidence in each of the direct, indirect, and NMA estimates based on methods developed by the GRADE working group. Using an example of a published NMA, we show that the quality of evidence supporting NMA estimates varies from high to very low across comparisons, and that quality ratings given to a whole network are uninformative and likely to mislead.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1136/bmj.g5630

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

GRADE guidelines: 3. Rating the quality of evidence
Balshem, H., Helfand, M., Schünemann, H. J., Oxman, A. D., Kunz, R., Brozek, J., Vist, G. E., Falck-Ytter, Y., Meerpohl, J., & Norris, S. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.015 · Cited by 8,285
Self-citation
GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology
Guyatt, G. H., Oxman, A. D., Schünemann, H. J., Tugwell, P., & Knottnerus, A. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.09.011 · Cited by 3,094
Self-citation
GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
Guyatt, G. H., Oxman, A. D., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P., Montori, V., Akl, E. A., Djulbegovic, B., & Falck-Ytter, Y. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.017 · Cited by 2,798
Self-citation
GRADE guidelines 6. Rating the quality of evidence—imprecision
Guyatt, G. H., Oxman, A. D., Kunz, R., Brozek, J., Alonso-Coello, P., Rind, D., Devereaux, P. J., Montori, V. M., Freyschuss, B., Vist, G., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.01.012 · Cited by 2,693
Self-citation
Checking consistency in mixed treatment comparison meta-analysis
Dias, S., Welton, N. J., Caldwell, D. M., & Ades, A. E. (2010) · Statistics in Medicine · doi:10.1002/sim.3767 · Cited by 2,521
Graphical tools for network meta-analysis in STATA
Chaimani, A., Higgins, J. P. T., Mavridis, D., Spyridonos, P., & Salanti, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076654 · Cited by 2,473
GRADE guidelines: 7. Rating the quality of evidence—inconsistency
Guyatt, G. H., Oxman, A. D., Kunz, R., Woodcock, J., Brozek, J., Helfand, M., Alonso-Coello, P., Glasziou, P., Jaeschke, R., Akl, E. A., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.03.017 · Cited by 2,320
Self-citation
Combination of direct and indirect evidence in mixed treatment comparisons
Lu, G., & Ades, A. E. (2004) · Statistics in Medicine · doi:10.1002/sim.1875 · Cited by 2,172
Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies
Higgins, J. P. T., Jackson, D., Barrett, J. K., Lu, G., Ades, A. E., & White, I. R. (2012) · Research Synthesis Methods · doi:10.1002/jrsm.1044 · Cited by 2,098
GRADE guidelines: 8. Rating the quality of evidence—indirectness
Guyatt, G. H., Oxman, A. D., Kunz, R., Woodcock, J., Brozek, J., Helfand, M., Alonso-Coello, P., Falck-Ytter, Y., Jaeschke, R., Vist, G., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.04.014 · Cited by 1,843
Self-citation

Show all 39 references

Sorted by citations

Items 101–200 of 1,001

Mass deworming to improve developmental health and wellbeing of children in low-income and middle-income countries: a systematic review and network meta-analysis
Welch, V. A., Ghogomu, E. A. T., Hossain, A., Awasthi, S., Bhutta, Z. A., Cumberbatch, C., Fletcher, R. H., McGowan, J., Krishnaratne, S., Kristjansson, E., et al. (2016) · The Lancet Global Health · doi:10.1016/s2214-109x(16)30242-x · Cited by 130
Use of network meta-analysis in clinical guidelines
Kanters, S., Ford, N., Druyts, E., Thorlund, K., Mills, E. J., & Bansback, N. (2016) · Bulletin of the World Health Organization · doi:10.2471/blt.16.174326 · Cited by 121
Identifying the Need for Good Practices in Health Technology Assessment: Summary of the ISPOR HTA Council Working Group Report on Good Practices in HTA
Kristensen, F. B., Husereau, D., Huić, M., Drummond, M., Berger, M. L., Bond, K., Augustovski, F., Booth, A., Bridges, J. F. P., Grimshaw, J., et al. (2018) · Value in Health · doi:10.1016/j.jval.2018.08.010 · Cited by 134
Duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stent: systematic review and network meta-analysis
Yin, S., Xu, P., Wang, B., Lu, Y., Wu, Q., Zhou, M.-L., Wu, J., Cai, J., Sun, X., & Yuan, H. (2019) · BMJ · doi:10.1136/bmj.l2222 · Cited by 121
Interventions for necrotising pancreatitis
Gurusamy, K. S., Belgaumkar, A. P., Haswell, A., Pereira, S. P., & Davidson, B. R. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011383.pub2 · Cited by 118
Prophylaxis against covid-19: living systematic review and network meta-analysis
Bartoszko, J. J., Siemieniuk, R. A., Kum, E., Qasim, A., Zeraatkar, D., Martinez, J. P. D., Azab, M., Ibrahim, S., Izcovich, A., Soto, G. B., et al. (2021) · BMJ · doi:10.1136/bmj.n949 · Cited by 113
Self-citation
Pharmacological treatment of oro‐facial pain – health technology assessment including a systematic review with network meta‐analysis
Häggman‐Henrikson, B., Alstergren, P. J., Davidson, T., Högestätt, E. D., Östlund, P., Tranæus, S., Vitols, S., & List, T. (2017) · Journal of Oral Rehabilitation · doi:10.1111/joor.12539 · Cited by 128
“The SBU system uses different terminology compared to the GRADE working group replacing ‘high quality’ with ‘strong evidence’, ‘moderate quality’ with ‘moderately strong evidence’, ‘low quality’ with ‘limited evidence’ and ‘very low quality’ with ‘insufficient evidence’ (23).”
Lifestyle Interventions for Weight Management in People With Serious Mental Illness: A Systematic Review With Meta-Analysis, Trial Sequential Analysis, and Meta-Regression Analysis Exploring the Mediators and Moderators of Treatment Effects
Speyer, H., Jakobsen, A. S., Westergaard, C., Nørgaard, H. C. B., Pisinger, C., Krogh, J., Hjorthøj, C., Nordentoft, M., Gluud, C., Correll, C. U., et al. (2019) · Psychotherapy and Psychosomatics · doi:10.1159/000502293 · Cited by 116
Methods to decrease blood loss during liver resection: a network meta-analysis
Moggia, E., Rouse, B., Simillis, C., Li, T., Vaughan, J., Davidson, B. R., & Gurusamy, K. S. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010683.pub3 · Cited by 112
Self-citation
Interventions for central serous chorioretinopathy: a network meta-analysis
Salehi, M., Wenick, A. S., Law, H. A., Evans, J. R., & Gehlbach, P. L. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011841.pub2 · Cited by 141
Systematic review and network meta‐analysis: efficacy of drugs for functional dyspepsia
Ford, A. C., Moayyedi, P., Black, C. J., Yuan, Y., Veettil, S. K., Mahadeva, S., Kengkla, K., Chaiyakunapruk, N., & Lee, Y. Y. (2020) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.16072 · Cited by 119
Comparative Effectiveness of Plain Balloon Angioplasty, Bare Metal Stents, Drug-Coated Balloons, and Drug-Eluting Stents for the Treatment of Infrapopliteal Artery Disease
Katsanos, K. H., Kitrou, P. M., Spiliοpoulos, S., Διαμαντόπουλος, Α., & Karnabatidis, D. (2016) · Journal of Endovascular Therapy · doi:10.1177/1526602816671740 · Cited by 112
Cardiovascular and Renal Outcomes of Renin–Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses
Catalá-López, F., Macías Saint-Gerons, D., González-Bermejo, D., Rosano, G. M., Davis, B. R., Ridao, M., Zaragoza, A., Montero-Corominas, D., Tobías, A., de la Fuente-Honrubia, C., et al. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1001971 · Cited by 109
“the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology [61,62] to evaluate the quality of evidence for each outcome (high, moderate, low, or very low quality).”
Method
Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Children: A Systematic Review and Network Meta- Analysis of Randomized Controlled Trials
Sun, M., Lai, H., Na, F., Li, S., Qiu, X., Tian, J., Zhang, Z., & Ge, L. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.0023 · Cited by 122
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: an abridged Cochrane network meta‐analysis
Weibel, S., Schaefer, M. S., Raj, D., Rücker, G., Pace, N. L., Schlesinger, T., Meybohm, P., Kienbaum, P., Eberhart, L. H. J., & Kranke, P. (2020) · Anaesthesia · doi:10.1111/anae.15295 · Cited by 110
“In making inferences regarding the choice of an intervention, recognising the certainty of each comparison is far more valuable than ranking efficacy alone [38].”
Background
Evidence-based clinical practice: Overview of threats to the validity of evidence and how to minimise them
Garattini, S. K., Jakobsen, J. C., Wetterslev, J., Bertelè, V., Banzi, R., Rath, A., Neugebauer, E. A. M., Laville, M., Masson, Y., Hivert, V., et al. (2016) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2016.03.020 · Cited by 112
Assessment of Postnatal Corticosteroids for the Prevention of Bronchopulmonary Dysplasia in Preterm Neonates
Ramaswamy, V. V., Bandyopadhyay, T., Nanda, D., Bandiya, P., Ahmed, J., Garg, A., Roehr, C. C., & Nangia, S. (2021) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2020.6826 · Cited by 114
Network Meta-Analysis
Schwarzer, G., Carpenter, J. R., & Rücker, G. (2015) · Use R! · doi:10.1007/978-3-319-21416-0_8 · Cited by 109
Living network meta-analysis compared with pairwise meta-analysis in comparative effectiveness research: empirical study
Nikolakopoulou, A., Mavridis, D., Furukawa, T. A., Cipriani, A., Tricco, A. C., Straus, S. E., Siontis, G. C. M., Egger, M., & Salanti, G. (2018) · BMJ · doi:10.1136/bmj.k585 · Cited by 109
Fluid type and the use of renal replacement therapy in sepsis: A systematic review and network meta-analysis.
for the FISSH Group (Fluids in Sepsis and Septic Shock), Rochwerg, B., Alhazzani, W., Gibson, A., Ribic, C. M., Sindi, A., Heels-Ansdell, D., Thabane, L., Fox-Robichaud, A., Mbuagbaw, L., et al. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3794-1 · Cited by 106
Self-citation
Dressings and topical agents for treating pressure ulcers
Westby, M. J., Dumville, J. C., Soares, M. O., Stubbs, N. C., & Norman, G. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011947.pub2 · Cited by 117
Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis
Ma, H., Lin, Y., Dai, L.-Z., Lin, C., Huang, Y., & Liu, S.-Y. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-061807 · Cited by 125
Functional somatic symptoms
Roenneberg, C., Sattel, H., Schaefert, R., Henningsen, P., & Hausteiner-Wiehle, C. (2019) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2019.0553 · Cited by 111
Comparative efficacy of different methods for difficult biliary cannulation in ERCP: systematic review and network meta-analysis
Facciorusso, A., Ramai, D., Gkolfakis, P., Khan, S. R., Papanikolaou, I. S., Τriantafyllou, Κ., Tringali, A., Chandan, S., Mohan, B. P., & Adler, D. G. (2021) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2021.09.010 · Cited by 104
Treatment of idiopathic pulmonary fibrosis: a network meta-analysis
Rochwerg, B., Neupane, B., Zhang, Y., Garcia, C. C., Raghu, G., Richeldi, L., Brozek, J., Beyene, J., & Schünemann, H. (2016) · BMC Medicine · doi:10.1186/s12916-016-0558-x · Cited by 101
“The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach specific to NMA served to assess the certainty in the evidence (quality of evidence) associated with specific comparisons, including direct, indirect, and final network meta-analysis estimates [20].”
BackgroundMethodSelf-citation
Efficacy of noninvasive respiratory support modes for primary respiratory support in preterm neonates with respiratory distress syndrome: Systematic review and network meta‐analysis
Ramaswamy, V. V., More, K., Roehr, C. C., Bandiya, P., & Nangia, S. (2020) · Pediatric Pulmonology · doi:10.1002/ppul.25011 · Cited by 105
“The confidence in the final estimates for all the outcomes was assessed using the GRADE approach as recommended by the GRADE working group.(22) 2.”
Method
Progestogens for preventing miscarriage: a network meta-analysis
Devall, A., Papadopoulou, A., Podesek, M., Haas, D. M., Price, M. J., Coomarasamy, A., & Gallos, I. D. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013792.pub2 · Cited by 111
“We used the GRADE working group's approach (Brignardello-Petersen 2018; Puhan 2014) for rating the certainty of the analysis eLect estimates for all the comparisons and all outcomes.”
Method
Very early versus delayed mobilisation after stroke
Langhorne, P., Collier, J. M., Bate, P. J., Thuy, M. N. T., & Bernhardt, J. A. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006187.pub3 · Cited by 103
Twenty years of network meta‐analysis: Continuing controversies and recent developments
Ades, A. E., Welton, N. J., Dias, S., Phillippo, D., & Caldwell, D. M. (2024) · Research Synthesis Methods · doi:10.1002/jrsm.1700 · Cited by 115
“67 The rating attached to each indirect estimate would be the lowest of the ratings of its two direct components.”
Influential
WHO recommendations on uterotonics for postpartum haemorrhage prevention: what works, and which one?
Vogel, J. P., Williams, M. J., Gallos, I. D., Althabe, F., & Oladapo, O. T. (2019) · BMJ Global Health · doi:10.1136/bmjgh-2019-001466 · Cited by 106
Comparative Efficacy of Treatment Options for Minimal Hepatic Encephalopathy: A Systematic Review and Network Meta-Analysis
Dhiman, R. K., Thumburu, K. K., Verma, N., Chopra, M., Rathi, S., Dutta, U., Singal, A. K., Taneja, S., Duseja, A. K., & Singh, M. (2019) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2019.08.047 · Cited by 100
GRADE guidelines 33: Addressing imprecision in a network meta-analysis
Brignardello‐Petersen, R., Guyatt, G. H., Mustafa, R. A., Chu, D. K., Hultcrantz, M., Schünemann, H. J., & TOMLINSON, G. A. (2021) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2021.07.011 · Cited by 103
Self-citation
Effectiveness and safety of prenatal valacyclovir for congenital cytomegalovirus infection: systematic review and meta‐analysis
D'Antonio, F., Marinceu, D., Prasad, S., & Khalil, A. A. (2022) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.26136 · Cited by 99
Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients With Moderate to Severe Acute Respiratory Distress Syndrome
Aoyama, H., Uchida, K., Aoyama, K., Pechlivanoglou, P., Englesakis, M. F., Yamada, Y., & Fan, E. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.8116 · Cited by 98
Treatments for Metastatic Hormone-sensitive Prostate Cancer: Systematic Review, Network Meta-analysis, and Benefit-harm assessment
Menges, D., Yebyo, H. G., Sivec-Muniz, S., Haile, S. R., Barbier, M. C., Tomonaga, Y., Schwenkglenks, M. M., & Puhan, M. A. (2022) · European Urology Oncology · doi:10.1016/j.euo.2022.04.007 · Cited by 99
Self-citation
Network meta-analysis on the effects of finerenone versus SGLT2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus and chronic kidney disease
Zhang, Y., Jiang, L., Wang, J., Wang, T., Chien, C., Huang, W., Fu, X., Xiao, Y., Fu, Q., Wang, S., et al. (2022) · Cardiovascular Diabetology · doi:10.1186/s12933-022-01676-5 · Cited by 96
Probiotics, Prebiotics, Lactoferrin, and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants
Wang, Y., Flórez, I. D., Morgan, R. L., Foroutan, F., Chang, Y., Crandon, H. N., Zeraatkar, D., Bała, M. M., Mao, R. Q., Tao, B. K.-L., et al. (2023) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2023.3849 · Cited by 103
Self-citation
Which Surgical Treatment for Open Tibial Shaft Fractures Results in the Fewest Reoperations? A Network Meta-analysis
Foote, C. J., Guyatt, G. H., Vignesh, N. K., Mundi, R., Chaudhry, H., Heels‐Ansdell, D., Thabane, L., Tornetta, P., & Bhandari, M. (2015) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-015-4224-y · Cited by 96
“We dealt with this issue by first identifying the sources of inconsistency (Tables 4 and 5), and second, by using only the highest confidence comparisons as the best estimate of effect, as recommended by the GRADE working group [32].”
MethodSelf-citation
Association of glucagon-like peptide 1 analogs and agonists administered for obesity with weight loss and adverse events: a systematic review and network meta-analysis
Vosoughi, K., Atieh, J., Khanna, L., Khoshbin, K., Prokop, L. J., Davitkov, P., Murad, M. H., & Camilleri, M. (2021) · eClinicalMedicine · doi:10.1016/j.eclinm.2021.101213 · Cited by 97
“Certainty in the pooled estimates was assessed using the GRADE approach for network meta-analysis [21].”
MethodSelf-citation
Comparative efficacy and safety of reperfusion therapy with fibrinolytic agents in patients with ST-segment elevation myocardial infarction: a systematic review and network meta-analysis
Jinatongthai, P., Kongwatcharapong, J., Foo, C. Y., Phrommintikul, A., Nathisuwan, S., Thakkinstian, A., Reid, C. M., & Chaiyakunapruk, N. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31441-1 · Cited by 96
Meta-Analysis and Meta-Synthesis Methodologies: Rigorously Piecing Together Research
Leary, H., & Walker, A. E. (2018) · TechTrends · doi:10.1007/s11528-018-0312-7 · Cited by 95
“Finally, results include the ranking probability for each treatment (Puhan et al. 2014) in two different forms (see Table 2 below).”
BackgroundMethodInfluential
Management of Acute Pain From Non–Low Back, Musculoskeletal Injuries
Busse, J. W., Sadeghirad, B., Oparin, Y., Chen, E., Goshua, A., May, C., Hong, P. J., Agarwal, A., Chang, Y., Ross, S. A., et al. (2020) · Annals of Internal Medicine · doi:10.7326/m19-3601 · Cited by 104
Self-citation
Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis
Wang, Y., Ye, Z., Ge, L., Siemieniuk, R. A. C., Wang, X., Wang, Y., Hou, L., Ma, Z., Agoritsas, T., Vandvik, P. O., et al. (2020) · BMJ · doi:10.1136/bmj.l6744 · Cited by 98
Self-citation
Management of people with early- or very early-stage hepatocellular carcinoma
Majumdar, A., Roccarina, D., Thorburn, D., Davidson, B. R., Tsochatzis, E. A., & Gurusamy, K. S. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011650.pub2 · Cited by 95
Network Meta-Analysis
Watt, J. A., & Giovane, C. D. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1566-9_12 · Cited by 97
Systematic review with network meta-analysis: comparative efficacy of pharmacologic therapies for fibrosis improvement and resolution of NASH
Majzoub, A. M., Nayfeh, T., Barnard, A., Munaganuru, N., Dave, S., Singh, S., Murad, M. H., & Loomba, R. (2021) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.16583 · Cited by 92
Self-citation
Risks of malignancies related to tofacitinib and biological drugs in rheumatoid arthritis: Systematic review, meta-analysis, and network meta-analysis
Maneiro, J. R., Souto, A., & Gómez-Reino, J. J. (2017) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2017.02.007 · Cited by 93
Biologics or tofacitinib for rheumatoid arthritis in incomplete responders to methotrexate or other traditional disease-modifying anti-rheumatic drugs: a systematic review and network meta-analysis.
Singh, J. A., Hossain, A., Tanjong-Ghogomu, E., Kotb, A., Christensen, R., Mudano, A., Maxwell, L. J., Shah, N. P., Tugwell, P., & Wells, G. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012183 · Cited by 88
Self-citation
Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis
Dulai, P. S., Singh, S., Marquez, E. O., Khera, R., Prokop, L. J., Limburg, P. J., Gupta, S. N., & Murad, M. H. (2016) · BMJ · doi:10.1136/bmj.i6188 · Cited by 92
Self-citation
Network meta-analysis: the highest level of medical evidence?
Faltinsen, E. G., Storebø, O. J., Jakobsen, J. C., Boesen, K., Lange, T., & Gluud, C. N. (2018) · BMJ Evidence-Based Medicine · doi:10.1136/bmjebm-2017-110887 · Cited by 89
“14 Salanti and colleagues further supported the use of a contribution matrix to summarise the quality input of each trial to a given indirect estimate,(14) an approach not advocated by Puhan and colleagues at the time.(12) Recent advances by the GRADE working group further challenged the assumption that quality rating…”
BackgroundMethodInfluential
Systemic Immunomodulatory Treatments for Atopic Dermatitis
Drucker, A. M., Lam, M., Prieto‐Merino, D., Malek, R., Ellis, A. G., Yiu, Z. Z. N., Rochwerg, B. N., Giorgio, S. D., Arents, B. W. M., Mohan, T., et al. (2024) · JAMA Dermatology · doi:10.1001/jamadermatol.2024.2192 · Cited by 102
Antivirals for treatment of severe influenza: a systematic review and network meta-analysis of randomised controlled trials
Gao, Y., Guyatt, G. H., Uyeki, T. M., Liu, M., Chen, Y., Zhao, Y., Shen, Y., Xu, J., Zheng, Q., Li, Z., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01307-2 · Cited by 100
Self-citation
Comparative efficacy and acceptability of cognitive behavioral therapy delivery formats for insomnia in adults: A systematic review and network meta-analysis
Gao, Y., Ge, L., Liu, M., Niu, M., Chen, Y., Sun, Y., Chen, J., Yao, L., Wang, Q., Li, Z., et al. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2022.101648 · Cited by 89
Comparative Efficacy of Colonoscope Distal Attachment Devices in Increasing Rates of Adenoma Detection: A Network Meta-analysis
Facciorusso, A., Prete, V. D., Buccino, R. V., Valle, N. D., Nacchiero, M. C., Monica, F., Cannizzaro, R., & Muscatiello, N. (2017) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2017.11.007 · Cited by 89
“We used Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria for network metaanalysis to appraise quality of evidence.(11)”
Method
Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation
Brazzelli, M. G., Javanbakht, M., Imamura, M., Hudson, J., Moloney, E., Becker, F., Wallace, S. A., Omar, M. I., Shimonovich, M., MacLennan, G., et al. (2019) · Health Technology Assessment · doi:10.3310/hta23140 · Cited by 89
Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: a systematic review and network meta-analysis
Florez, I. D., Veroniki, A.-A., Al Khalifah, R., Yepes-Nuñez, J. J., Sierra, J. M., Vernooij, R. W. M., Acosta-Reyes, J., Granados, C. M., Pérez-Gaxiola, G., Cuello-Garcia, C., et al. (2018) · PLOS ONE · doi:10.1371/journal.pone.0207701 · Cited by 87
Self-citation
Desensitizing Toothpastes for Dentin Hypersensitivity: A Network Meta-analysis
Martins, C. C., Firmino, R. T., Riva, J. J., Ge, L., Carrasco‐Labra, A., Brignardello‐Petersen, R., Colunga‐Lozano, L. E., Granville‐Garcia, A. F., Costa, F. O., Yepes-Núñez, J. J., et al. (2020) · Journal of Dental Research · doi:10.1177/0022034520903036 · Cited by 91
Self-citation
Probiotic Supplementation during the Perinatal and Infant Period: Effects on gut Dysbiosis and Disease
Navarro‐Tapia, E., Sebastiani, G., Sailer, S., Almeida-Toledano, L., Serra-Delgado, M., García‐Algar, Ó., & Andreu-Férnández, V. (2020) · Nutrients · doi:10.3390/nu12082243 · Cited by 86
“The colonization of pathogenic microbes, which leads to dysbiosis in preterm infants, is linked to the delayed introduction of human milk, early antibiotic intervention, a high rate of caesarean delivery, and total parenteral nutrition [152].”
Background
Perineural and intravenous dexamethasone and dexmedetomidine: network meta‐analysis of adjunctive effects on supraclavicular brachial plexus block
Sehmbi, H., Brull, R., Ceballos, K. R., Shah, U. J., Martin, J. E., Tobı́as, A., Solo, K., & Abdallah, F. W. (2020) · Anaesthesia · doi:10.1111/anae.15288 · Cited by 93
Comparative efficacy of exercise therapy and oral non-steroidal anti-inflammatory drugs and paracetamol for knee or hip osteoarthritis: a network meta-analysis of randomised controlled trials
Weng, Q., Goh, S.-L., Wu, J., Persson, M. S. M., Wei, J., Sarmanova, A., Li, X., Hall, M., Doherty, M., Jiang, T., et al. (2023) · British Journal of Sports Medicine · doi:10.1136/bjsports-2022-105898 · Cited by 84
Compared Abilities of Endoscopic Techniques to Increase Colon Adenoma Detection Rates: A Network Meta-analysis
Facciorusso, A., Τriantafyllou, Κ., Murad, M. H., Prokop, L. J., Tziatzios, G., Muscatiello, N., & Singh, S. (2018) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2018.11.058 · Cited by 84
Self-citation
Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta‐analysis
Tan‐Lim, C. S. C., Esteban‐Ipac, N. A. R., Mantaring, J. B. V., Shih‐Yen, E. C., Recto, M. S. T., Sison, O. T., & Alejandria, M. M. (2020) · Pediatric Allergy and Immunology · doi:10.1111/pai.13305 · Cited by 85
Comparative efficacy of various endoscopic techniques for the treatment of common bile duct stones: a network meta-analysis
Park, C. H., Jung, J. H., Nam, E., Kim, E. H., Kim, M. G., Kim, J. H., & Park, S. W. (2017) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2017.07.038 · Cited by 82
Systematic review with network meta‐analysis: comparative effectiveness and safety of strategies for preventing NSAID ‐associated gastrointestinal toxicity
Yuan, J.-Q., Tsoi, K. K. F., Yang, M. G., Wang, J. Y., Threapleton, D. E., Yang, Z., Zou, B., Mao, C., Tang, J. L., & Chan, F. K. L. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13642 · Cited by 86
“The quality of evidence was graded as ‘high’, ‘moderate’, ‘low’ and ‘very low’ based on the fundamental study design and additional methodological factors.(21) For network meta-analysis, we firstly rated the quality of the direct and indirect evidence separately.”
BackgroundMethod
Efficacy and Tolerability of Sodium-Glucose Co-Transporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists: A Systematic Review and Network Meta-Analysis
Hussein, H., Zaccardi, F., Khunti, K., Davies, M. J., Patsko, E., Dhalwani, N. N., Kloecker, D. E., Ioannidou, E., & Gray, L. J. (2020) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.14008 · Cited by 82
“Quality of evidence for the primary outcome was assessed using the GRADE working group approach for the primary outcome.(26) Design-by-treatment models were fitted to assess inconsistency, where possible.”
Method
Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis
Siemieniuk, R. A., Bartoszko, J. J., Díaz Martinez, J. P., Kum, E., Qasim, A., Zeraatkar, D., Izcovich, A., Mangala, S., Ge, L., Han, M. A., et al. (2021) · BMJ · doi:10.1136/bmj.n2231 · Cited by 79
“14 Two methodologists with experience in using GRADE rated each domain for each comparison independently, resolving discrepancies by discussion.”
Self-citation
Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta-analysis.
Singh, J. A., Hossain, A., Tanjong-Ghogomu, E., Mudano, A., Maxwell, L. J., Buchbinder, R., Lopez-Olivo, M., Suarez-Almazor, M., Tugwell, P., & Wells, G. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012591 · Cited by 65
Self-citation
Efficacy and tolerability of atypical antipsychotics for acute bipolar depression: a network meta-analysis
Kadakia, A., Dembek, C., Heller, V., Singh, R., Uyei, J., Hagi, K., Nosaka, T., & Loebel, A. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03220-3 · Cited by 79
“Ratings were based on the following domains: study design, risk of bias, inconsistency, indirectness, imprecision, and publication bias [28].”
Method
Therapeutic Options for Neuroendocrine Tumors
Kaderli, R. M., Spanjol, M., Kollár, A., Bütikofer, L., Gloy, V., Dumont, R. A., Seiler, C. A., Christ, E., Radojewski, P., Briel, M., et al. (2019) · JAMA Oncology · doi:10.1001/jamaoncol.2018.6720 · Cited by 83
Treatment of newly diagnosed glioblastoma in the elderly: a network meta-analysis
Hanna, C. R., Lawrie, T. A., Rogozińska, E., Kernohan, A., Jefferies, S., Bulbeck, H., Ali, U. M., Robinson, T., & Grant, R. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013261.pub2 · Cited by 79
Comparative Effectiveness of Calcimimetic Agents for Secondary Hyperparathyroidism in Adults: A Systematic Review and Network Meta-analysis
Palmer, S. C., Mavridis, D., Johnson, D. W., Tonelli, M. A., Ruospo, M., & Strippoli, G. F. (2020) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2020.02.439 · Cited by 85
Negative Symptom Interventions in Youth at Risk of Psychosis: A Systematic Review and Network Meta-analysis
Devoe, D. J. A., Peterson, A. M., & Addington, J. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx139 · Cited by 82
Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a network meta-analysis
Piechotta, V., Adams, A., Haque, M., Scheckel, B., Kreuzberger, N., Monsef, I., Jordan, K., Kuhr, K., & Skoetz, N. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012775.pub2 · Cited by 79
Comparative diagnostic performance of different techniques for EUS-guided fine-needle biopsy sampling of solid pancreatic masses: a network meta-analysis
Facciorusso, A., Crinò, S. F., Ramai, D., Madhu, D., Fugazza, A., Carrara, S., Spadaccini, M., Mangiavillano, B., Gkolfakis, P., Mohan, B. P., et al. (2023) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2023.01.024 · Cited by 80
Attenuated psychotic symptom interventions in youth at risk of psychosis: A systematic review and meta‐analysis
Devoe, D. J. A., Farris, M. S., Townes, P., & Addington, J. (2018) · Early Intervention in Psychiatry · doi:10.1111/eip.12677 · Cited by 86
“In the NMA, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to evaluate the quality of evidence associated with the results in the NMA at each time point (Puhan et al., 2014).”
Method
Preoxygenation before intubation in adult patients with acute hypoxemic respiratory failure: a network meta-analysis of randomized trials
Fong, K. M., Au, S. Y., & Ng, G. W. Y. (2019) · Critical Care · doi:10.1186/s13054-019-2596-1 · Cited by 79
“When both direct and indirect evidence were available, we chose the higher of the two quality ratings for the NMA estimate [17].”
BackgroundMethod
Efficacy of noninvasive respiratory support modes as postextubation respiratory support in preterm neonates: A systematic review and network meta‐analysis
Ramaswamy, V. V., Bandyopadhyay, T., Nanda, D., Bandiya, P., More, K., Oommen, V. I., & Gupta, A. (2020) · Pediatric Pulmonology · doi:10.1002/ppul.25007 · Cited by 79
“Surface under the cumulative ranking curve (SUCRA) plots were used to rank the different NRS modalities for all the outcomes.19 The quality of evidence was graded using the GRADE approach for NMA.20”
MethodInfluential
Biologics or tofacitinib for people with rheumatoid arthritis naive to methotrexate: a systematic review and network meta-analysis.
Singh, J. A., Hossain, A., Mudano, A., Tanjong-Ghogomu, E., Suarez-Almazor, M., Buchbinder, R., Maxwell, L. J., Tugwell, P., & Wells, G. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012657 · Cited by 71
Self-citation
Prescribed exercise programs may not be effective in reducing impairments and improving activity during upper limb fracture rehabilitation: a systematic review
Bruder, A. M., Shields, N., Dodd, K., & Taylor, N. F. (2017) · Journal of physiotherapy · doi:10.1016/j.jphys.2017.08.009 · Cited by 78
Comparative Effectiveness of Phosphate Binders in Patients with Chronic Kidney Disease: A Systematic Review and Network Meta-Analysis
Sekercioglu, N., Thabane, L., Martinez, J. P. D., NESRALLAH, G. E., Longo, C. J., Busse, J. W., Akhtar‐Danesh, N., Agarwal, A., Khalifah, R. A. A., Iorio, A., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156891 · Cited by 80
Self-citation
Treatment for hepatorenal syndrome in people with decompensated liver cirrhosis: a network meta-analysis
Best, L. M., Freeman, S. C., Sutton, A. J., Cooper, N. J., Tng, E.-L., Csenar, M., Hawkins, N., Pavlov, C. S., Davidson, B. R., Thorburn, D., et al. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013103.pub2 · Cited by 79
“Puhan 2014 Puhan MA, Schünemann HJ, Murad MH, Li T, BrignardelloPetersen R, Singh JA, et al. A GRADE Working Group approach for rating the quality of treatment eEect estimates from network meta-analysis.”
Influential
Interventions for the Management of Computer Vision Syndrome
Singh, S., McGuinness, M. B., Anderson, A. J., & Downie, L. E. (2022) · Ophthalmology · doi:10.1016/j.ophtha.2022.05.009 · Cited by 87
Some conservative interventions are more effective than others for people with chronic non-specific neck pain: a systematic review and network meta-analysis
Castellini, G., Pillastrini, P., Vanti, C., Bargeri, S., Giagio, S., Bordignon, E., Fasciani, F., Marzioni, F., Innocenti, T., Chiarotto, A., et al. (2022) · Journal of physiotherapy · doi:10.1016/j.jphys.2022.09.007 · Cited by 95
Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta‐analysis of randomized clinical trials
Nagendrababu, V., Pulikkotil, S. J., Suresh, A., Veettil, S. K., Bhatia, S., & Setzer, F. C. (2019) · International Endodontic Journal · doi:10.1111/iej.13072 · Cited by 79
“The quality of evidence was rated as ‘high’, ‘moderate’, ‘low’ and ‘very low’ (Puhan et al. 2014).”
Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials
Dayyani, M., Sadeghirad, B., Grotta, J. C., Zabihyan, S., Ahmadvand, S., Wang, Y., Guyatt, G. H., & Amin‐Hanjani, S. (2022) · Stroke · doi:10.1161/strokeaha.121.035699 · Cited by 80
Self-citation
Comparative efficacy of mepolizumab, benralizumab, and dupilumab in eosinophilic asthma: A Bayesian network meta-analysis
Akenroye, A. T., Lassiter, G., Jackson, J. W., Keet, C. A., Segal, J. B., Alexander, G. C., & Hong, H. (2022) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2022.05.024 · Cited by 79
Minimally Invasive Treatments for Benign Prostatic Obstruction: A Systematic Review and Network Meta-analysis
Cornu, J., Zantek, P. F., Burtt, G., Martin, C., Martin, A. E., Springate, C., & Chughtai, B. I. (2023) · European Urology · doi:10.1016/j.eururo.2023.02.028 · Cited by 76
Delivery Room Interventions for Hypothermia in Preterm Neonates
Abiramalatha, T., Ramaswamy, V. V., Bandyopadhyay, T., Pullattayil, A. K., Thanigainathan, S., Trevisanuto, D., & Roehr, C. C. (2021) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2021.0775 · Cited by 79
Management of patellar tendinopathy: a systematic review and network meta-analysis of randomised studies
Challoumas, D., Pedret, C., Biddle, M., Ng, N. Y. B., Kirwan, P., Cooper, B., Nicholas, P., Wilson, S., Clifford, C., & Millar, N. L. (2021) · BMJ Open Sport & Exercise Medicine · doi:10.1136/bmjsem-2021-001110 · Cited by 75
“8 9 Strength of evidence assessment was performed by DC and MB independently and any disagreements were resolved by discussion and involvement of a third assessor (NLM).”
Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta-analysis
Rodriguez, M. B., Dias, S., Jordan, V., Lethaby, A. E., Lensen, S. F., WISE, M. R., Wilkinson, J., Brown, J., & Farquhar, C. M. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013180.pub2 · Cited by 82
Systematic Review and Meta-Analysis Examining the Effectiveness of Mobile Health Technologies in Using Self-Monitoring for Pediatric Weight Management
Darling, K. E., & Sato, A. F. (2017) · Childhood Obesity · doi:10.1089/chi.2017.0038 · Cited by 75
Pharmacological interventions for non-alcohol related fatty liver disease (NAFLD)
Lombardi, R., Onali, S., Thorburn, D., Davidson, B. R., Gurusamy, K. S., & Tsochatzis, E. A. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011640.pub2 · Cited by 74
Comparison between general, spinal, epidural, and combined spinal-epidural anesthesia for cesarean delivery: a network meta-analysis
Kim, W. H., Hur, M. S., Park, S.-K., Yoo, S., Lim, T. Y., Yoon, H., Kim, J., & Bahk, J.-H. (2018) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2018.09.012 · Cited by 88
Use of corticoids and non-steroidal anti-inflammatories in the treatment of rheumatoid arthritis: Systematic review and network meta-analysis
Paglia, M. D. G., Silva, M. T., Lopes, L. C., Barberato-Filho, S., Mazzei, L. G., Abe, F. C., & Bergamaschi, C. D. C. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248866 · Cited by 81
“We followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to appraise the confidence in estimates derived from network meta-analysis of outcomes [34, 37].”
Method
Threshold Analysis as an Alternative to GRADE for Assessing Confidence in Guideline Recommendations Based on Network Meta-analyses
Phillippo, D., Dias, S., Welton, N. J., Caldwell, D. M., Taske, N., & Ades, A. E. (2019) · Annals of Internal Medicine · doi:10.7326/m18-3542 · Cited by 71
“GRADE NMA then combines these judgements in a subjective manner to reach an overall judgement, whereas Salanti GRADE uses an objective statistical rationale to reach an overall judgement.”
Influential
The Changing Therapeutic Role of Chemo-radiotherapy for Loco-regionally Advanced Nasopharyngeal Carcinoma from Two/Three-Dimensional Radiotherapy to Intensity-Modulated Radiotherapy: A Network Meta-Analysis
You, R., Cao, Y.-S., Huang, P., Chen, L., Yang, Q., Liu, Y.-P., Zou, X., Zhang, Y.-N., Jiang, R., Zhang, M., et al. (2017) · Theranostics · doi:10.7150/thno.21815 · Cited by 72
Methods for managing miscarriage: a network meta-analysis
Ghosh, J., Papadopoulou, A., Devall, A., Jeffery, H. C., Beeson, L. E., Do, V., Price, M. J., Tobı́as, A., Tunçalp, Ö., Lavelanet, A. F., et al. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012602.pub2 · Cited by 74
Topical Fluoride to Prevent Root Caries: Systematic Review with Network Meta-analysis
Zhang, J., Sardana, D., Li, K. Y., Leung, K., & Lo, E. C. M. (2020) · Journal of Dental Research · doi:10.1177/0022034520906384 · Cited by 80
“For indirect comparison, intransitivity, imprecision, and the lowest-certainty ratings for the direct comparisons formed the first-order loop (Puhan et al. 2014).”
Background
Comparison of Antiviral Agents for Seasonal Influenza Outcomes in Healthy Adults and Children
Liu, J.-W., Lin, S.-H., Wang, L.-C., Chiu, H.-Y., & Lee, J. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.19151 · Cited by 73
Living cumulative network meta-analysis to reduce waste in research: A paradigmatic shift for systematic reviews?
Vandvik, P. O., Brignardello-Petersen, R., & Guyatt, G. H. (2016) · BMC Medicine · doi:10.1186/s12916-016-0596-4 · Cited by 69
“Authors have already presented two systems based on GRADE principles for making quality of evidence ratings in NMAs [21, 22].”
InfluentialSelf-citation

Authors: Puhan, M. A., Schunemann, H. J., Murad, M. H., Li, T., Brignardello-Petersen, R., Singh, J. A., Kessels, A. G., Guyatt, G. H., & for the GRADE Working Group
Affiliations: University of Zurich (CH)
Mayo Clinic (US)
Johns Hopkins University (US)
University of Alabama (US)
Maastricht University (NL)
McMaster University (CA)
Corresponding author: Puhan, M. A.
ORCID: Puhan, M. A.
Murad, M. H.
Li, T.
Singh, J. A.
Guyatt, G. H.
Venue: BMJ
Publisher: BMJ
Published: 2014-09-24
Volume: 349
Issue: sep24 5
Pages: g5630-g5630
ISSN: 1756-1833 (ISSN-L)
DOI: 10.1136/bmj.g5630
OpenAlex: W2155798268
Cited by: 1,812
References: 39
Citations by year: 2026: 160 · 2025: 177 · 2024: 216 · 2023: 175 · 2022: 205 · 2021: 276 · 2020: 201 · 2019: 128 · 2018: 96 · 2017: 72 · 2016: 63 · 2015: 36 · 2014: 4
FWCI: 57.15
Type: journal article
Language: en
Update notices: correction (2015-06-17)
Open access: bronze
doi.org
Locations: BMJ (publishedVersion)
PubMed (publishedVersion)
Research Publications (Maastricht University) (publishedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
HighWire Press Open Archive (submittedVersion)
Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
Research Publications (Maastricht University) (submittedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich)
Topics: Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Social Sciences › Sociology and Political Science › Delphi Technique in Research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Keywords: network meta-analysis, quality of evidence, GRADE, treatment effect estimates, comparative effectiveness
MeSH terms: Humans, Quality Assurance, Health Care, Meta-Analysis as Topic, Practice Guidelines as Topic, Evidence-Based Medicine, Guideline Adherence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks