Ultra-high-risk paradigm: lessons learnt and new directions
Open accessAbstract
Within the embryonic early psychosis field in the early 1990s, the conceptualisation and definition of an at-risk or ultra-high-risk (UHR) mental state for psychosis was a breakthrough which transformed the clinical and research landscape in psychiatry. Twenty-five years later, we have a new evidence base that has illuminated the neurobiology of the onset phase of psychotic disorder, delivered Cochrane level 1 evidence showing that the onset of full-threshold sustained psychotic disorder can be at least delayed, and is paving the way to a new generation of transdiagnostic research. Here, we document the contribution of the UHR approach to understanding the underlying mechanisms of psychosis onset as well as the long-term outcomes. Particularly, we highlight that psychosis onset can be delayed in those meeting UHR criteria and that these criteria have a higher valence for subsequent psychotic disorders and some valence for persistent non-psychotic syndromes. Critiques have helped to identify some of the limitations of this paradigm, which are acknowledged. These include evidence that psychotic disorders can emerge more acutely and from other, as yet undefined, precursor states. Rather than defending, or alternatively questioning the value of, the UHR approach, we propose a broader, transdiagnostic staging model that is consistent with the pluripotent and variably comorbid trajectories for mental disorders. This approach moves beyond psychosis to capture a wider range of subthreshold symptoms and full-threshold disorders, thus enhancing prediction for the emergence and progression of a range of mental disorders, as well as providing new avenues for early intervention and prevention.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A trans-diagnostic clinical high-risk mental state (CHARMS) paradigm may increase capacity to intercept a wider range of lower risk cases than those with attenuated psychotic symptoms only, including people with sub-threshold bipolar and borderline personality symptoms as well as mild-moderate depression.
“a trans-diagnostic clinical high-risk mental state (CHARMS) paradigm may increase capacity to intercept a wider range of lower risk cases than those with attenuated psychotic symptoms only, including people with sub-threshold bipolar and borderline personality symptoms as well as mild-moderate depression [22]”
From Prevention and early intervention in youth mental health: is it time for a multidisciplinary and trans-diagnostic model for care? (2020) · cites this paper as [22]
Progress has been made for psychotic disorders due to successful application of an at-risk mental state concept.
“While progress has been made for psychotic disorders, also due to the successful application of an at-risk mental state concept [22]”
From Prevention and early intervention in youth mental health: is it time for a multidisciplinary and trans-diagnostic model for care? (2020) · cites this paper as [22]
Pathways to mental disorders are pluripotent and trans-diagnostic.
“increasingly clear evidence that pathways to mental disorders are pluripotent and trans-diagnostic [22]”
From Prevention and early intervention in youth mental health: is it time for a multidisciplinary and trans-diagnostic model for care? (2020) · cites this paper as [22]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Predicting Psychosis: Meta-analysis of Transition Outcomes in Individuals at High Clinical Risk
Fusar-Poli, P. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1472 · Cited by 1,361 · see citing works
Linscott, R. J., & van Os, J. (2013) · Psychological Medicine · doi:10.1017/s0033291712001626 · Cited by 1,181 · see citing works
McGorry, P. D., Hickie, I. B., Yung, A. R., Pantelis, C., & Jackson, H. J. (2006) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2006.01860.x · Cited by 919 · see citing works
Self-citationResearch Domain Criteria: cognitive systems, neural circuits, and dimensions of behavior
Morris, S. E., & Cuthbert, B. N. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.1/smorris · Cited by 638 · see citing works
Psychotic Experiences in the General Population
McGrath, J. J., Saha, S., Al-Hamzawi, A., Alonso, J., Bromet, E. J., Bruffaerts, R., Caldas‐de‐Almeida, J. M., Chiu, W. T., de Jonge, P., Fayyad, J. A., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.0575 · Cited by 597 · see citing works
Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry
McGorry, P. D., Hartmann, J. A., Spooner, R., & Nelson, B. (2018) · World Psychiatry · doi:10.1002/wps.20514 · Cited by 488 · see citing works
Self-citation(2014) · Choice Reviews Online · doi:10.5860/choice.51-3280 · Cited by 449 · see citing works
Declining Transition Rate in Ultra High Risk (Prodromal) Services: Dilution or Reduction of Risk?
Yung, A. R., Yuen, H. P., Berger, G. E., Francey, S. M., Hung, T.-C., Nelson, B., Phillips, L., & McGorry, P. D. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm015 · Cited by 412 · see citing works
Self-citationvan der Gaag, M., Smit, F., Bechdolf, A., French, P., Linszen, D. H., Yung, A. R., McGorry, P., & Cuijpers, P. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.07.004 · Cited by 384 · see citing works
Self-citationA paradigm shift in psychiatric classification: the Hierarchical Taxonomy Of Psychopathology (HiTOP)
Kotov, R., Krueger, R. F., & Watson, D. (2018) · World Psychiatry · doi:10.1002/wps.20478 · Cited by 317 · see citing works
Biomarkers and clinical staging in psychiatry
McGorry, P. D., Keshavan, M. S., Goldstone, S. D., Amminger, G. P., Allott, K., Berk, M., Lavoie, S., Pantelis, C., Yung, A. R., Wood, S. J., et al. (2014) · World Psychiatry · doi:10.1002/wps.20144 · Cited by 305 · see citing works
Self-citationIntegrated (one‐stop shop) youth health care: best available evidence and future directions
Hetrick, S. E., Bailey, A. P., Smith, K. E., Malla, A., Mathias, S., Singh, S. P., O'Reilly, A., Verma, S. K., Benoit, L., Fleming, T. M., et al. (2017) · Medical Journal of Australia · doi:10.5694/mja17.00694 · Cited by 288 · see citing works
Self-citationOutcomes of Nontransitioned Cases in a Sample at Ultra-High Risk for Psychosis
Lin, A., Wood, S. J., Nelson, B., Beavan, A., McGorry, P., & Yung, A. R. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.13030418 · Cited by 277 · see citing works
Self-citationFusar-Poli, P., Rocchetti, M., Sardella, A., Avila, A., Brandizzi, M., Caverzasi, E., Politi, P., Ruhrmann, S., & McGuire, P. (2015) · British Journal of Psychiatry · doi:10.1192/bjp.bp.114.157115 · Cited by 272 · see citing works
McGorry, P. D., Nelson, B., Markulev, C., Yuen, H. P., Schäfer, M. R., Mossaheb, N., Schlögelhofer, M., Smesny, S., Hickie, I. B., Berger, G. E., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.2902 · Cited by 262 · see citing works
Self-citationA critique of the “ultra‐high risk” and “transition” paradigm
van Os, J., & Guloksuz, S. (2017) · World Psychiatry · doi:10.1002/wps.20423 · Cited by 261 · see citing works
Cultures for mental health care of young people: an Australian blueprint for reform
McGorry, P. D., Goldstone, S. D., Parker, A. G., Rickwood, D. J., & Hickie, I. B. (2014) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00082-0 · Cited by 221 · see citing works
Self-citationCuijpers, P. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.8.1385 · Cited by 217 · see citing works
van Os, J., & Linscott, R. J. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr188 · Cited by 213 · see citing works
McGorry, P., & Nelson, B. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.2868 · Cited by 211 · see citing works
Self-citationRickwood, D. J., Telford, N. R., Parker, A. G., Tanti, C. J., & McGorry, P. D. (2014) · Medical Journal of Australia · doi:10.5694/mja13.11235 · Cited by 207 · see citing works
Self-citationKelleher, I., Devlin, N. M., Wigman, J. T. W., Kehoe, A., Murtagh, A., Fitzpatrick, C., & Cannon, M. D. (2013) · Psychological Medicine · doi:10.1017/s0033291713002122 · Cited by 174 · see citing works
Randomized Controlled Trial of Interventions for Young People at Ultra-High Risk of Psychosis
McGorry, P. D., Nelson, B., Phillips, L., Yuen, H. P., Francey, S. M., Thampi, A., Berger, G. E., Amminger, G. P., Simmons, M. B., Kelly, D., et al. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12m07785 · Cited by 142 · see citing works
Self-citationHartmann, J., Nelson, B., Spooner, R., Amminger, G. P., Chanen, A. M., Davey, C. G., McHugh, M. J., Ratheesh, A., Treen, D., Yuen, H. P., et al. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12483 · Cited by 97 · see citing works
Self-citationThe Ultra-High Risk Concept—A Review
Yung, A. R., & Nelson, B. (2013) · The Canadian Journal of Psychiatry · doi:10.1177/070674371305800103 · Cited by 94 · see citing works
Valmaggia, L., Byrne, M., Day, F., Broome, M. R., Johns, L., Howes, O. D., Power, P., Badger, S., Fusar‐Poli, P., & McGuire, P. K. (2015) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.114.150623 · Cited by 82 · see citing works
Clinical trajectories in the ultra-high risk for psychosis population
Polari, A. R., Lavoie, S., Yuen, H. P., Amminger, G. P., Berger, G. E., Chen, E. Y. H., de Haan, L., Hartmann, J., Markulev, C., Melville, F., et al. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.01.022 · Cited by 82 · see citing works
Self-citationShah, J. L., Crawford, A., Mustafa, S., Iyer, S. N., Joober, R., & MALLA, A. K. (2017) · Psychiatric Services · doi:10.1176/appi.ps.201600304 · Cited by 80 · see citing works
Mapping prodromal psychosis: A critical review of neuroimaging studies
Fusar‐Poli, P., McGuire, P. K., & Borgwardt, S. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2011.06.006 · Cited by 75 · see citing works
Nelson, B., Amminger, G. P., Yuen, H. P., Wallis, N., Kerr, M., Dixon, L. B., Carter, C., Loewy, R. L., Niendam, T. A., Shumway, M., et al. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12459 · Cited by 75 · see citing works
Self-citationPurcell, R., Jorm, A. F., Hickie, I. B., Yung, A. R., Pantelis, C., Amminger, G. P., Glozier, N., Killackey, E. J., Phillips, L., Wood, S. J., et al. (2014) · Early Intervention in Psychiatry · doi:10.1111/eip.12133 · Cited by 67 · see citing works
Self-citationLee, T. Y., Lee, J., Kim, M., Choe, E., & Kwon, J. S. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx173 · Cited by 62 · see citing works
Woods, S. W., Powers, A. R., Taylor, J. H., Davidson, C. A., Johannesen, J., Addington, J., Perkins, D. O., Bearden, C. E., Cadenhead, K. S., Cannon, T. D., et al. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx138 · Cited by 57 · see citing works
Henry, L. P., Harris, M., Amminger, G. P., Yuen, H. P., Harrigan, S., Lambert, M., Conus, P., Schwartz, O., Prosser, A. L., Farrelly, S. E., et al. (2007) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2007.00008.x · Cited by 48 · see citing works
Self-citationPhillips, L., Cotton, S., Mihalopoulos, C., Shih, S. T. F., Yung, A. R., Carter, R., & McGorry, P. D. (2009) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2008.00106.x · Cited by 37 · see citing works
Self-citationFirst episode psychosis : looking backwards and forwards
Ajnakina, O. (2017) · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Colizzi, M., Lasalvia, A., & Ruggeri, M. (2020) · International Journal of Mental Health Systems · doi:10.1186/s13033-020-00356-9 · Cited by 727 · see citing works
Koutsouleris, N., Dwyer, D. B., Degenhardt, F., Maj, C., Urquijo-Castro, M. F., Sanfelici, R., Popovic, D., Oeztuerk, O., Haas, S. S., Weiske, J., et al. (2021) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2020.3604 · Cited by 275 · see citing works
Hartmann, J., McGorry, P. D., Destrée, L., Amminger, G. P., Chanen, A. M., Davey, C. G., Ghieh, R., Polari, A. R., Ratheesh, A., Yuen, H. P., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.553578 · Cited by 86 · see citing works
Self-citationGuloksuz, S., Pries, L., ten Have, M., de Graaf, R., van Dorsselaer, S., Klingenberg, B., Bak, M., Lin, B. D., van Eijk, K. R., Delespaul, P., et al. (2020) · World Psychiatry · doi:10.1002/wps.20755 · Cited by 72 · see citing works
Annual Research Review: Translational machine learning for child and adolescent psychiatry
Dwyer, D., & Koutsouleris, N. (2022) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13545 · Cited by 65 · see citing works
Raballo, A., Poletti, M., Preti, A., & McGorry, P. D. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.03.063 · Cited by 59 · see citing works
Self-citationLång, U., Ramsay, H., Yates, K., Veijola, J., Gyllenberg, D., Clarke, M., Leacy, F., Gissler, M., & Kelleher, I. (2022) · World Psychiatry · doi:10.1002/wps.21009 · Cited by 56 · see citing works
Lång, U., Yates, K., Leacy, F. P., Clarke, M. C., McNicholas, F., Cannon, M. D., & Kelleher, I. (2021) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2021.07.593 · Cited by 56 · see citing works
The ‘Parma‐Early Psychosis’ programme: Characterization of help‐seekers with first episode psychosis
Landi, G., Leuci, E., Quattrone, E., Azzali, S., Pellegrini, C., Pellegrini, P., & Pelizza, L. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.12968 · Cited by 32 · see citing works
Gender-Oriented Mental Health Prevention: A Reappraisal
Comacchio, C., Antolini, G., Ruggeri, M., & Colizzi, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19031493 · Cited by 27 · see citing works
Self‐esteem in individuals at ultra‐high risk for psychosis: A systematic review and meta‐analysis
Bemrose, H. V., Akande, I., & Cullen, A. E. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13034 · Cited by 22 · see citing works
Berendsen, S., Van, H. L., van der Paardt, J. W., de Peuter, O. R., van Bruggen, M., Nusselder, H., Jalink, M., Peen, J., Dekker, J., & de Haan, L. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13006 · Cited by 22 · see citing works
Silverstein, S. M., Thompson, J. L., Gold, J. M., Schiffman, J. E., Waltz, J. A., Williams, T. F., Zinbarg, R. E., Mittal, V. A., Ellman, L. M., Strauss, G. P., et al. (2021) · Schizophrenia · doi:10.1038/s41537-021-00156-1 · Cited by 21 · see citing works
Puntis, S., Oliver, D., & Fusar-Poli, P. (2021) · Schizophrenia Research · doi:10.1016/j.schres.2021.01.005 · Cited by 21 · see citing works
Poletti, M., Azzali, S., Paterlini, F., Garlassi, S., Scazza, I., Chiri, L. R., Pupo, S., Raballo, A., & Pelizza, L. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.552282 · Cited by 20 · see citing works
Transcending false dichotomies and diagnostic silos to reduce disease burden in mental disorders
McGorry, P. D., Nelson, B., Wood, S. J., Shah, J. L., MALLA, A. K., & Yung, A. R. (2020) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-020-01913-w · Cited by 19 · see citing works
Self-citationWijnen, B. F. M., Thielen, F. W. F., Konings, S. R. A., Feenstra, T., van der Gaag, M., Veling, W., de Haan, L., Ising, H. K., Hiligsmann, M., Evers, S., et al. (2019) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1080/14737167.2019.1632194 · Cited by 18 · see citing works
The Autism–Psychosis Continuum Conundrum: Exploring the Role of the Endocannabinoid System
Colizzi, M., Bortoletto, R., Costa, R., Bhattacharyya, S., & Balestrieri, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19095616 · Cited by 14 · see citing works
de Jong, Y., Boon, A., Gouw, D., van der Gaag, M., & Mulder, C. (2022) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-022-00459-w · Cited by 9 · see citing works
Lee, T. Y., Lee, J., Lee, H. J., Lee, Y., Rhee, S. J., Park, D. Y., Paek, M. J., Kim, E. Y., Kim, E., Roh, S., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00340 · Cited by 10 · see citing works
Breaking the web: life beyond the at-risk mental state for psychosis
Pérez, J., & Jones, P. B. (2019) · Psychological Medicine · doi:10.1017/s0033291719002605 · Cited by 10 · see citing works
Berhe, O., Höflich, A. S., Moessnang, C., Reichert, M., Kremer, T. L., Gan, G., Ma, R., Braun, U., Reininghaus, U., Ebner‐Priemer, U., et al. (2022) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.06.009 · Cited by 8 · see citing works
Broadening the Parameters of Clinical High Risk for Psychosis
Cotter, D., Healy, C., Staines, L., Mongan, D., & Cannon, M. D. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20220612 · Cited by 8 · see citing works
Illness Phase as a Key Assessment and Intervention Window for Psychosis
Kohler, C. G., Wolf, D. H., Abi‐Dargham, A., Anticevic, A., Cho, Y., Fonteneau, C., Gil, R. B., Girgis, R. R., Gray, D. L., Grinband, J., et al. (2022) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2022.05.009 · Cited by 8 · see citing works
Giordano, G. M., Palumbo, D., Pontillo, M., Mucci, A., Galderisi, S., & Vicari, S. (2022) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgac025 · Cited by 7 · see citing works
Berendsen, S., van der Paardt, J. W., Van, H. L., van Bruggen, M., Nusselder, H., Jalink, M., de Peuter, O. R., Peen, J., van Tricht, M. J., & de Haan, L. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109856 · Cited by 7 · see citing works
Colizzi, M., Basaldella, M., Candolo, A., Garzitto, M., Palermo, A., Scipioni, C., Tavian, G., Balestrieri, M., Bortoletto, R., & Comacchio, C. (2024) · Early Intervention in Psychiatry · doi:10.1111/eip.13604 · Cited by 6 · see citing works
Song, W., Xu, L., Zhang, T., Wang, W., Fu, Y., Xu, Q., Yuan, R., Ning, A., Wang, J., Lin, G. N., et al. (2022) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13346 · Cited by 5 · see citing works
Ologundudu, O. M., Palaniyappan, L. K., Cipriano, L. E., Wijnen, B. F. M., Anderson, K. K., & Ali, S. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.09.015 · Cited by 5 · see citing works
van Aubel, E., Vaessen, T., van Winkel, R., Lafit, G., Klippel, A., Viechtbauer, W., Batink, T., van der Gaag, M., van Amelsvoort, T., Marcelis, M. C., et al. (2022) · medRxiv · doi:10.1101/2022.01.19.22269524 · Cited by 5 · see citing works
Lisi, A. D., Leuci, E., Quattrone, E., Azzali, S., Paulillo, G., Pupo, S., Pellegrini, P., Marco, M., & Pelizza, L. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.09.005 · Cited by 4 · see citing works
Asadiof, F., Zamanpour, M., Al-Hussainy, A. F., Shalal, A. A. A.-H., Ubaid, M., Aluquaily, Z. H., & Hashemian, S. H. (2024) · Iranian Journal of Psychiatry · doi:10.18502/ijps.v20i1.17405 · Cited by 3 · see citing works
Schematic beliefs, negative affect and paranoia in at‐risk youth
Crowter, L., Banerjee, R. A., Berry, C., & Fowler, D. G. (2022) · British Journal of Clinical Psychology · doi:10.1111/bjc.12373 · Cited by 2 · see citing works
Magnani, L., Carmisciano, L., Dell’Orletta⋄, F., Bettinardi, O., Chiesa, S., Imbesi, M., Limonta, G., Montagna, E., Turone, I., Martinasso, D., et al. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-066642 · Cited by 3 · see citing works
Ten priorities that are shaping the future of mental health prevention
Colizzi, M. (2025) · Discover Mental Health · doi:10.1007/s44192-025-00290-7 · Cited by 4 · see citing works
Karakuş, O. B., Doganer, M. Z., Turhan, İ. Y., Cesur, T. D., Çakır, E. Ö., Yüksel, A. S., Çek, D., Sevin, İ. B., ESİN, İ. S., & Rizvi, S. J. (2025) · Psychiatric Quarterly · doi:10.1007/s11126-025-10177-z · Cited by 1 · see citing works
Cognitive Impairment in Schizophrenia: Definition, Classification, and Course
Penadés, R., Mezquida, G., Forte, M. F., & Ayesa, R. (2025) · Comprehensive approach to psychiatry · doi:10.1007/978-3-032-06209-3_8 · Cited by 1 · see citing works
de Jong, Y., Boon, A., Mulder, C. L., & van der Gaag, M. (2024) · Early Intervention in Psychiatry · doi:10.1111/eip.13597 · Cited by 1 · see citing works
Bortoletto, R., Garzitto, M., Piscitelli, F., Fornasaro, S., Scipioni, C., Sepulcri, O., Fabris, M., Curcio, F., Balestrieri, M., & Colizzi, M. (2024) · Brain Sciences · doi:10.3390/brainsci14121230 · Cited by 1 · see citing works
Cortese, S., Carlson, G. A., & James, A. C. (2018) · Evidence-Based Mental Health · doi:10.1136/ebmental-2018-300066 · Cited by 1 · see citing works
The effectiveness and feasibility of preventive interventions for psychoses
Dorofeikova, M., & Петрова, Н. Н. (2019) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro2019119081108
Clinical staging in depression
de la Fuente-Tomás, L., & García‐Portilla, M. P. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-817933-8.00026-8
Some changes in white blood cells in fasting rats after total-body irradiation.
Šamánek, M., Hampl, V., & Tušl, M. (1967) · PubMed
Müller, S., Hellenschmidt, T., & Kölch, M. G. (2020) · Springer eBooks · doi:10.1007/978-3-662-58418-7_14
Is There Room for Anti-stigma Interventions in Mental Health Preventive Programmes?
Lasalvia, A. (2022) · Springer eBooks · doi:10.1007/978-3-030-97906-5_10
Esordi psicotici in adolescenza e giovane età adulta: prospettive teoriche e di trattamento
Paterlini, F. (2022) · RIVISTA SPERIMENTALE DI FRENIATRIA · doi:10.3280/rsf2022-003003
Bortoletto, R., Garzitto, M., Piscitelli, F., Comacchio, C., Curcio, F., Fabris, M., Sepulcri, O., Balestrieri, M., & Colizzi, M. (2024) · Research Square · doi:10.21203/rs.3.rs-3814137/v1
High-risk state for psychosis: psychometric screening tools
Царьков, И. Е., Новоселова, А. Э., Zhilyaeva, T. V., & Mazo, G. E. (2024) · V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY · doi:10.31363/2313-7053-2024-832
Recent Insights in the Treatment for Clinical High Risk for Psychosis and Recent Onset Psychosis
Park, S., Jo, Y. T., Lee, J. S., Lee, J. S., & Park, I. H. (2024) · Korean Journal of Schizophrenia Research · doi:10.16946/kjsr.2024.27.2.35
Chen, Y., Ereshefsky, S., Yau, S., González, Á. D. S., Joo, S., Niendam, T. A., & Shapiro, D. I. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07597-3
Brady, F., Stanojlovic, A., Naughton, S., Clarke, M., Gaynor, K., & Kessler, K. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.09.040
Melillo, A., Micheli, A. D., Nandha, S., Gadelrab, R., Jauhar, S., Young, A. H., Azis, M., Manchia, M., Pfennig, A., Mucci, A., et al. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1773189
- Authors
- McGorry, P. D., & Mei, C.
- Affiliations
- The University of Melbourne (AU)
- Corresponding author
- McGorry, Patrick D
- Venue
- Evidence Based Mental Health
- Publisher
- BMJ
- Published
- 2018-10-24
- Volume
- 21
- Issue
- 4
- Pages
- 131-133
- ISSN
- 1362-0347 (ISSN-L)
- 1468-960X
- PMC
- PMC10270365
- OpenAlex
- W2898193019
- Cited by
- 52
- References
- 36
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 8 · 2023: 2 · 2022: 14 · 2021: 6 · 2020: 11 · 2019: 3 · 2018: 1
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Evidence-Based Mental Health (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- National Health and Medical Research Council
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- transition to psychosis, early psychosis, psychosis risk syndromes, subthreshold symptoms, long-term outcomes, early intervention, prevention, comorbidities
- MeSH terms
- Humans, Psychotic Disorders, Disease Progression, Risk Assessment, Prodromal Symptoms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
