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The role of mast cells in functional GI disorders
Open accessAbstract
Functional gastrointestinal disorders (FGIDs) are characterized by chronic complaints arising from disorganized brain-gut interactions leading to dysmotility and hypersensitivity. The two most prevalent FGIDs, affecting up to 16–26% of worldwide population, are functional dyspepsia and irritable bowel syndrome. Their etiopathogenic mechanisms remain unclear, however, recent observations reveal low-grade mucosal inflammation and immune activation, in association with impaired epithelial barrier function and aberrant neuronal sensitivity. These findings come to challenge the traditional view of FGIDs as pure functional disorders, and relate the origin to a tangible organic substrate. The mucosal inflammatory infiltrate is dominated by mast cells, eosinophils and intraepithelial lymphocytes in the intestine of FGIDs. It is well established that mast cell activation can generate epithelial and neuro-muscular dysfunction and promote visceral hypersensitivity and altered motility patterns in FGIDs, postoperative ileus, food allergy and inflammatory bowel disease. This review will discuss the role of mucosal mast cells in the gastrointestinal tract with a specific focus on recent advances in disease mechanisms and clinical management in irritable bowel syndrome and functional dyspepsia.
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Citations
Cites
Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis
Lovell, R. M., & Ford, A. C. (2012) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2012.02.029 · Cited by 2,155
Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G. S., Santini, D., Pasquinelli, G., Morselli-Labate, A. M., Grady, E. F., Bunnett, N. W., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.055 · Cited by 1,475
Spiller, R. C., Jenkins, D., Thornley, J. P., Hebden, J. M., Wright, T., Skinner, M., & Neal, K. R. (2000) · Gut · doi:10.1136/gut.47.6.804 · Cited by 1,155
Mast cell-orchestrated immunity to pathogens
Abraham, S. N., & John, A. L. S. (2010) · Nature reviews. Immunology · doi:10.1038/nri2782 · Cited by 959
Activation of the mucosal immune system in irritable bowel syndrome
Chadwick, V. S., Chen, W., Shu, D., Paulus, B., Bethwaite, P., Tie, A., & Wilson, I. (2002) · Gastroenterology · doi:10.1053/gast.2002.33579 · Cited by 833
Mast Cell-Dependent Excitation of Visceral-Nociceptive Sensory Neurons in Irritable Bowel Syndrome
Barbara, G., Wang, B., Stanghellini, V., de Giorgio, R., Cremon, C., Di Nardo, G., Trevisani, M., Campi, B., Geppetti, P., Tonini, M., et al. (2007) · Gastroenterology · doi:10.1053/j.gastro.2006.11.039 · Cited by 783
Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
Galli, S. J., Grimbaldeston, M. A., & Tsai, M. M. (2008) · Nature reviews. Immunology · doi:10.1038/nri2327 · Cited by 757
Böhn, L., Störsrud, S., Törnblom, H., Bengtsson, U., & Simrén, M. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.105 · Cited by 655
da Silva, E. Z. M., Jamur, M. C., & Oliver, C. (2014) · Journal of Histochemistry & Cytochemistry · doi:10.1369/0022155414545334 · Cited by 645
Bischoff, S. C. (2007) · Nature reviews. Immunology · doi:10.1038/nri2018 · Cited by 631
Cited by
Sorted by citations
Items 101–200 of 307
Clinical efficacy and safety of ketotifen in treating irritable bowel syndrome with diarrhea
Wang, J., Wang, Y., Zhou, H., Gu, W., Wang, X., & Yang, J. (2020) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000001737 · Cited by 31
Salvo‐Romero, E., Rodiño‐Janeiro, B. K., Albert-Bayo, M., Lobo, B., Santos, J., Farré, R., Martínez, C., & Vicario, M. (2022) · Cells · doi:10.3390/cells11101644 · Cited by 32
Self-citationNanagas, V. C., & Kovalszki, A. (2018) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-018-8695-y · Cited by 31
Tangible pathologies in functional dyspepsia
Walker, M. M., Potter, M. D. E., & Talley, N. J. (2019) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2019.101650 · Cited by 30
Daddam, J. R., Sreenivasulu, B., Peddanna, K., & Katike, U. (2020) · RSC Advances · doi:10.1039/c9ra09245e · Cited by 30
High-throughput screening of cell-free riboswitches by fluorescence-activated droplet sorting
Tabuchi, T., & Yokobayashi, Y. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac152 · Cited by 30
Mischopoulou, M., D’Ambrosio, M., Bigagli, E., Luceri, C., Farrugia, G., & Cipriani, G. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.02.017 · Cited by 31
Therapeutic Potentials of A2B Adenosine Receptor Ligands: Current Status and Perspectives
Chandrasekaran, B., Samarneh, S., Jaber, A. M. Y., Kassab, G. H., & Agrawal, N. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190717105834 · Cited by 29
Guilarte, M., Vicario, M., Martínez, C., de Torres, I., Lobo, B., Pigrau, M., González-Castro, A., Rodiño-Janeiro, B., Salvo-Romero, E., Fortea, M., et al. (2020) · American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000789 · Cited by 28
Self-citationSodium Sulfite-Induced Mast Cell Pyroptosis and Degranulation
Liu, M., Lu, J., Chen, Y., Shi, X., Li, Y., Yang, S., Yu, J. Y., & Guan, S. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c02436 · Cited by 29
Sui, C., Tao, L., Bai, C., Shao, L., Miao, J., Chen, K., Wang, M., Hu, Q., & Wang, F. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.929901 · Cited by 28
Hagiwara, S., Kaushal, E., Paruthiyil, S., Pasricha, P. J., Hasdemir, B., & Bhargava, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0203704 · Cited by 28
Aziz, Q., Harris, L. A., Goodman, B. P., Simrén, M., & Shin, A. (2025) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2025.02.015 · Cited by 27
Lee, E. H., Yang, H. R., & Lee, H. S. (2018) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm18050 · Cited by 29
Kamphuis, J. B. J., Reber, L. L., Eutamène, H., & Théodorou, V. (2022) · The FASEB Journal · doi:10.1096/fj.202100494rrr · Cited by 27
Chun, E., Yoon, S., Parveen, A., & Jin, M. (2018) · Nutrients · doi:10.3390/nu10101475 · Cited by 28
Mohammadi, M., Mirzaei, H., & Motallebi, M. (2021) · Anaerobe · doi:10.1016/j.anaerobe.2021.102501 · Cited by 26
Towards a new paradigm of microscopic colitis: Incomplete and variant forms
Guagnozzi, D., Landolfi, S., & Vicario, M. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i38.8459 · Cited by 25
Self-citationImpact of Prebiotics on Enteric Diseases and Oxidative Stress
Gao, J., Azad, M. A. K., Han, H. L., Wan, D., & Li, T. (2020) · Current Pharmaceutical Design · doi:10.2174/1381612826666200211121916 · Cited by 26
Neuro-innate immune interactions in gut mucosal immunity
Kulkarni, S., Kurapati, S., & Bogunovic, M. (2020) · Current Opinion in Immunology · doi:10.1016/j.coi.2020.09.007 · Cited by 25
The role of intestinal mast cell infiltration in irritable bowel syndrome
Cheng, L., Luo, Q., & Chen, S. (2021) · Journal of Digestive Diseases · doi:10.1111/1751-2980.12971 · Cited by 25
Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain
Rahman-Enyart, A., Yang, W., Yaggie, R. E., White, B. A., Welge, M. E., Auvil, L. S., Berry, M. S., Bushell, C., Rosen, J. M., Rudick, C. N., et al. (2021) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00106.2021 · Cited by 25
Singh, R., Zogg, H., & Ro, S. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11101021 · Cited by 25
di Vito, R., Mezza, A. D., Conte, C., & Traina, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24044157 · Cited by 25
Mast Cells Exert Anti-Inflammatory Effects in an IL10−/−Model of Spontaneous Colitis
Lennon, E. M., Borst, L. B., Edwards, L., & Moeser, A. J. (2018) · Mediators of Inflammation · doi:10.1155/2018/7817360 · Cited by 26
Berg, L. K., Goll, R., Fagerli, E., Ludviksen, J. K., Fure, H., Moen, O. S., Sørbye, S. W., Mollnes, T. E., & Florholmen, J. (2020) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2020.1754455 · Cited by 24
The Role of Leaky Gut in Functional Dyspepsia
Wauters, L. I., Ceulemans, M., Schol, J., Farré, R., Tack, J. F., & Vanuytsel, T. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.851012 · Cited by 24
Gong, L., Li, J., Tang, Y., Han, T., Wei, C., Yu, X., Li, J., Wang, R., Ma, X., Liu, K., et al. (2016) · Scientific Reports · doi:10.1038/srep31452 · Cited by 24
Shin, D. W., Yoon, H., Kim, H. S., Choi, Y. J., Shin, C. M., Park, Y. S., Kim, N., & Lee, D. H. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/9147914 · Cited by 26
Zhang, L., Song, J., Bai, T., Wang, R., & Hou, X. (2018) · Neurogastroenterology & Motility · doi:10.1111/nmo.13430 · Cited by 24
Zhu, C., Zhao, L., Zhao, J., & Zhang, S. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4394 · Cited by 24
Kodani, M., Fukui, H., Tomita, T., Oshima, T., Watari, J., & Miwa, H. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.8926 · Cited by 23
van Bergenhenegouwen, J., Braber, S., Loonstra, R., Buurman, N., Rutten, L., Knipping, K., Savelkoul, P. J. M., Harthoorn, L. F., Jahnsen, F. L., Garssen, J., et al. (2018) · Nutrition Research · doi:10.1016/j.nutres.2018.07.005 · Cited by 23
Zhong, C., Liu, K., Wang, K., Liu, H., Su, H., Wu, J., & Duan, L. (2018) · Diseases of the Esophagus · doi:10.1093/dote/doy039 · Cited by 22
Coeliac Disease and Mast Cells
Frossi, B., Carli, M., & Calabrò, A. S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143400 · Cited by 22
Zhang, L., Song, J., Bai, T., Qian, W., & Hou, X. (2017) · Scientific Reports · doi:10.1038/s41598-017-05064-y · Cited by 21
Synthesis of anti-allergic drugs
Zhou, S., & Huang, G. (2020) · RSC Advances · doi:10.1039/c9ra10659f · Cited by 21
Alonso, C., Abril-Gil, M., Albert-Bayo, M., Mall, J. G., Expósito, E., González-Castro, A. M., Lobo, B., & Santos, J. (2021) · Advances in Therapy · doi:10.1007/s12325-021-01676-z · Cited by 23
Self-citationRole of inflammation in pediatric irritable bowel syndrome
Nardo, G. D., Cremon, C., Staiano, A., Stanghellini, V., Borrelli, O., Strisciuglio, C., Romano, C., Mallardo, S., Scarpato, E., Marasco, G., et al. (2022) · Neurogastroenterology & Motility · doi:10.1111/nmo.14365 · Cited by 21
Santos, M. L. C., Júnior, R. T. D. S., de Brito, B. B., da Silva, F. A. F., Marques, H. S., Gonçalves, V. L. D. S., dos Santos, T. C., Cirne, C. L., Silva, N. O. E., Oliveira, M. V., et al. (2022) · World Journal of Clinical Pediatrics · doi:10.5409/wjcp.v11.i2.105 · Cited by 21
Class A and C GPCR Dimers in Neurodegenerative Diseases
Moreira, I. S., Caniceiro, A. B., Bueschbell, B., & Schiedel, A. C. (2022) · Current Neuropharmacology · doi:10.2174/1570159x20666220327221830 · Cited by 18
Rodiño‐Janeiro, B. K., Martínez, C., Fortea, M., Lobo, B., Pigrau, M., Nieto, A., González-Castro, A. M., Salvo‐Romero, E., Guagnozzi, D., Pardo‐Camacho, C., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-20540-9 · Cited by 20
Self-citationLi, Y., Yang, T., Yao, Q., Li, S., Fang, E., Li, Y., Liu, C., & Li, W.-M. (2019) · Neurogastroenterology & Motility · doi:10.1111/nmo.13556 · Cited by 21
Migraine associated with gastrointestinal disorders: A pathophysiological explanation
Noghani, M. T., & Namdar, H. (2019) · Medical Hypotheses · doi:10.1016/j.mehy.2019.02.041 · Cited by 21
Fungal feelings in the irritable bowel syndrome: the intestinal mycobiome and abdominal pain
van Thiel, I. A. M., de Jonge, W., & van den Wijngaard, R. M. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2168992 · Cited by 20
Losso, J. N. (2021) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-062520-090235 · Cited by 18
Song, X., Pi, S., Gao, Y., Zhou, F., Yan, S., Chen, Y., Qiao, L., Dou, X., Shao, D., & Xu, C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.723173 · Cited by 18
Zhang, H., Wang, G., Xiong, Z., Liao, Z., Qian, Y., Song, X., Sui, L., Ai, L., & Xia, Y. (2023) · Food Science and Human Wellness · doi:10.26599/fshw.2022.9250059 · Cited by 18
Shao, M., Yuan, F., Liu, J., & Luo, H. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s383812 · Cited by 17
miR‐10b‐5p rescues leaky gut linked with gastrointestinal dysmotility and diabetes
Zogg, H., Singh, R., Ha, S. E., Wang, Z., Jin, B., Ha, M., Dafinone, M. E., Batalon, T., Hoberg, N., Poudrier, S. M., et al. (2023) · United European Gastroenterology Journal · doi:10.1002/ueg2.12463 · Cited by 17
Effects of Lizhong Tang on gastrointestinal motility in mice
Lee, M. C., Ha, W.-R., Park, J., Kim, J., Jung, Y., & Kim, B. J. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i34.7778 · Cited by 17
Functional gastrointestinal disorders in children: What is new?
Nightingale, S. L., & Sharma, A. (2020) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.14857 · Cited by 18
Clinical potential of eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome
Sobolewska-Włodarczyk, A., Włodarczyk, M., Storr, M., & Fichna, J. (2016) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s83722 · Cited by 18
Gut Non-Bacterial Microbiota: Emerging Link to Irritable Bowel Syndrome
Liu, A., Gao, W., Zhu, Y., Hou, X., & Chu, H. (2022) · Toxins · doi:10.3390/toxins14090596 · Cited by 18
The proteolytic activity in inflammatory bowel disease: insight from gut microbiota
Hou, J., Ding, L., Yang, T., Yang, Y.-F., Jin, Y., Zhang, X., Ma, A.-H., & Qin, Y. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.106560 · Cited by 20
The Emerging Role of Mast Cells in Irritable Bowel Syndrome.
Boeckxstaens, G. E. (2018) · Europe PMC (PubMed Central) · Cited by 16
The relationship between gut microbiota and proteolytic activity in irritable bowel syndrome
Hou, J., Wang, X., Li, Y., Su, S., Wang, Y., & Wang, B. (2021) · Microbial Pathogenesis · doi:10.1016/j.micpath.2021.104995 · Cited by 18
Polyphenols from Olive-Mill Wastewater and Biological Activity: Focus on Irritable Bowel Syndrome
Curci, F., Corbo, F., Clodoveo, M. L., Salvagno, L., Rosato, A., Corazza, I., Budriesi, R., Micucci, M., & Mattioli, L. (2022) · Nutrients · doi:10.3390/nu14061264 · Cited by 15
Vanheel, H., Vicario, M., Beeckmans, D., Cocca, S., Wauters, L. I., Accarie, A., Tóth, J. G., Rodewald, H.-R., Hertogh, G. D., Matteoli, G., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-74491-1 · Cited by 15
Self-citationLocalisation of Cannabinoid and Cannabinoid-Related Receptors in the Horse Ileum
Galiazzo, G., Tagliavia, C., Giancola, F., Rinnovati, R., Sadeghinezhad, J., Bombardi, C., Grandis, A., Pietra, M., & Chiocchetti, R. (2021) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2021.103688 · Cited by 17
Effects of Immune Cells on Intestinal Stem Cells: Prospects for Therapeutic Targets
Ma, L., Yu, J., Zhang, H., Zhao, B. T., Zhang, J., Yang, D., Luo, F., Wang, B., Jin, B., & Liu, J. (2022) · Stem Cell Reviews and Reports · doi:10.1007/s12015-022-10347-7 · Cited by 15
Gastrointestinal Motility, Mucosal Mast Cell, and Intestinal Histology in Rats: Effect of Prednisone
de Lima, M. B., Gama, L. A., Hauschildt, A. T., Dall’Agnol, D. J. R., Corá, L. A., & Américo, M. F. (2017) · BioMed Research International · doi:10.1155/2017/4637621 · Cited by 15
Han, Y., Peng, X.-M., Zhang, H.-X., Chen, S., & Zhang, L.-Y. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/1975228 · Cited by 14
Accarie, A., Tóth, J. G., Wauters, L. I., Farré, R., Tack, J. F., & Vanuytsel, T. (2022) · Cells · doi:10.3390/cells11071214 · Cited by 14
Sciuto, M., & Catanzaro, R. (2023) · Acta Microbiologica et Immunologica Hungarica · doi:10.1556/030.2023.02134 · Cited by 15
Parisio, C., Lucarini, E., Micheli, L., Toti, A., Bellumori, M., Cecchi, L., Calosi, L., Bani, D., Mannelli, L. D. C., Mulinacci, N., et al. (2020) · Food & Function · doi:10.1039/d0fo02293d · Cited by 15
Progress on the Mechanism of Visceral Hypersensitivity in Nonerosive Reflux Disease
Xu, C., & Niu, X. (2022) · Gastroenterology Research and Practice · doi:10.1155/2022/4785077 · Cited by 14
What Is the Value of Counting Mast Cells in Gastrointestinal Mucosal Biopsies?
Panarelli, N. C., Hornick, J. L., & Yantiss, R. K. (2023) · Modern Pathology · doi:10.1016/j.modpat.2022.100005 · Cited by 17
Role of mast cell-miR-490-5p in irritable bowel syndrome
Ren, H., Zhang, F., Luo, H., Zhang, G., & Liang, L. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i1.93 · Cited by 14
Wang, Z., Hao, M., Wu, L., He, Y., & Sun, X. (2022) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2022.2141075 · Cited by 13
Steinsvik, E. K., Hausken, T., Fluge, Ø., Mella, O., & Gilja, O. H. (2023) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2023.2173533 · Cited by 13
Staller, K. D., Olén, O., Söderling, J. K., Roelstraete, B., Törnblom, H., Kuo, B., Nguyen, L. H., & Ludvigsson, J. F. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17736 · Cited by 15
Lembo, A. J., Chey, W., Harris, L. A., Frazier, R. D., Brenner, D. M., Chang, L., Lacy, B. E., Edelstein, S., Yang, Y., Zhao, S.-L., et al. (2024) · American Journal of Gastroenterology · doi:10.14309/ajg.0000000000002685 · Cited by 13
Ballout, J., Ott, D., & Diener, M. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00329 · Cited by 13
Anticolitic Effect ofViscum coloratumthrough Suppression of Mast Cell Activation
Yoo, J., Park, K., & Yeul, J. (2019) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x19500101 · Cited by 13
Pruritogenic mechanisms and gut sensation: putting the “irritant” into irritable bowel syndrome
Brizuela, M., Castro, J., Harrington, A. M., & Brierley, S. M. (2021) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00331.2020 · Cited by 12
Mast Cell Activation Syndrome and Gut Dysfunction: Diagnosis and Management
Hamilton, M. J. (2024) · Current Gastroenterology Reports · doi:10.1007/s11894-024-00924-w · Cited by 12
Šojat, D., Volarić, M., Keškić, T., Volarić, N., Cerovečki, V., & Majnarić, L. T. (2024) · Biomedicines · doi:10.3390/biomedicines12030702 · Cited by 12
Asano, T., & Takenaga, M. (2017) · Journal of Clinical Medicine · doi:10.3390/jcm6110104 · Cited by 12
The antagonistic activity of H1 receptor antagonists as medicinal foods
Zhou, S., Huang, G., & Chen, G. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.08.018 · Cited by 12
Irritable bowel syndrome is strongly associated with the primary and idiopathic mast cell disorders
Kurin, M., Elangovan, A., Alikhan, M. M., Dulaijan, B. A., Silver, E., Kaelber, D. C., & Cooper, G. S. (2021) · Neurogastroenterology & Motility · doi:10.1111/nmo.14265 · Cited by 13
Utilizing mast cells in a positive manner to overcome inflammatory and allergic diseases
Zhang, Z., Ernst, P. B., Kiyono, H., & Kurashima, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.937120 · Cited by 12
Establishment and Characterization of a Murine Mucosal Mast Cell Culture Model
Kakinoki, A., Kameo, T., Shoko, Y., Furuta, K., & Tanaka, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010236 · Cited by 11
Jahng, J., & Kim, Y. S. (2016) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm16043 · Cited by 12
Gu, M., Fan, R., Dai, X., Gu, C. J., Wang, A., Wei, W., & Yang, S. (2023) · Animals · doi:10.3390/ani13040586 · Cited by 11
Increased Mast Cell Activation in Mongolian Gerbils Infected by Hepatitis E Virus
Liu, T., Xiao, P., Li, R., She, R., Tian, J., Wang, J., Mao, J., Yin, J., & Shi, R. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02226 · Cited by 11
Mast cells in human digestive tube in normal and pathological conditions
Rizzi, A., Enrico Crivellato, B., Benagiano, V., & Ribatti, D. (2016) · Immunology Letters · doi:10.1016/j.imlet.2016.07.002 · Cited by 11
Kress, I. U., Paslakis, G., & Erim, Y. (2018) · Zeitschrift für psychosomatische Medizin und Psychotherapie · doi:10.13109/zptm.2018.64.1.4 · Cited by 11
Lucarini, E., Micheli, L., Pagnotta, E., Toti, A., Ferrara, V., Ciampi, C., Margiotta, F., Martelli, A., Testai, L., Calderone, V., et al. (2022) · Nutrients · doi:10.3390/nu14153137 · Cited by 10
Shao, M., Liu, J., Liu, J., Yuan, F., & Deng, Y. (2022) · Experimental Physiology · doi:10.1113/ep090635 · Cited by 9
Annexin A1 Mimetic Peptide Ac2-26 Modulates the Function of Murine Colonic and Human Mast Cells
de Oliveira, M. P., Prates, J., Gimenes, A. D., Correa, S. G., & Oliani, S. M. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.689484 · Cited by 9
Microbiome and Gut Immunity: Innate Immune Cells
Strowig, T., Thiemann, S., & Diefenbach, A. (2018) · Springer eBooks · doi:10.1007/978-3-319-90545-7_8 · Cited by 9
Increased Mast Cell Counts and Degranulation in Microscopic Colitis
Chi, Z., Xu, J., & Saxena, R. (2020) · Gastroenterology Research and Practice · doi:10.1155/2020/9089027 · Cited by 9
Metabolic biomarkers in irritable bowel syndrome diagnosis
Vakili, O., Sedeh, P. A., & Pourfarzam, M. (2024) · Clinica Chimica Acta · doi:10.1016/j.cca.2024.119753 · Cited by 8
Harris, L. A., Cash, B. D., Moftah, K., & Franklin, H. (2021) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001567 · Cited by 8
[Neuroimmunomodulation in allergic rhinitis].
Cai, S., & Lou, H. (2021) · PubMed Central · doi:10.13201/j.issn.2096-7993.2021.09.021 · Cited by 8
Mucosal Mast Cell Distribution in the Gastrointestinal Tract of Children
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Shulman, R. J., Öhman, L., Stridsberg, M., Cain, K. C., Simrén, M., & Heitkemper, M. M. (2018) · Neurogastroenterology & Motility · doi:10.1111/nmo.13486 · Cited by 8
Cheng, Y.-C., Lee, H.-L., Hwang, Y., & Kim, S. W. (2022) · Journal of Animal Science · doi:10.1093/jas/skac396 · Cited by 7
Yang, Q., Zhao, Y., Zhao, X., Sun, S., Chen, Y., Chen, J., Zou, D., & Zhang, L. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116701 · Cited by 8
Metadata
- Authors
- Wouters, M. M., Vicario, M., & Santos, J.
- Affiliations
- Universitair Ziekenhuis Leuven (BE)
- Neuro-immuno-gastroenterology Laboratory, Digestive Diseases Research Unit. Vall d'Hebron Institut de Recerca, Department of Gastroenterology, Hospital Universitari Vall d'Hebron & Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain
- Universitat Autònoma de Barcelona (ES)
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2015-07-20
- Volume
- 65
- Issue
- 1
- Pages
- 155-168
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W1897161389
- Cited by
- 308
- References
- 144
- Citations by year
- 2026: 15 · 2025: 15 · 2024: 23 · 2023: 26 · 2022: 47 · 2021: 38 · 2020: 33 · 2019: 29 · 2018: 31 · 2017: 26 · 2016: 23 · 2015: 2
- FWCI
- 4.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- PubMed (publishedVersion)
- Lirias (submittedVersion, other-oa)
- Funders
- Fonds Wetenschappelijk Onderzoek (1248513 N)
- Ministerio de Economía y Competitividad (CP10/00502 &, CP10/00502, PI14/, PI11/00716 &, PI11/00716, PI14/00944, PI13/00935)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CB06/04/0021)
- Instituto de Salud Carlos III (PI13/00935, CB06/04/0021, PI11/, PI14/)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Immunology and Microbiology › Immunology › Mast cells and histamine
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Keywords
- mast cells, functional gastrointestinal disorders, irritable bowel syndrome, functional dyspepsia, visceral hypersensitivity, intestinal motility, mucosal inflammation, epithelial barrier function, eosinophils, intraepithelial lymphocytes, gut-brain axis, postoperative ileus, food allergy, inflammatory bowel disease
- MeSH terms
- Dyspepsia, Gastrointestinal Motility, Humans, Hypersensitivity, Intestinal Mucosa, Mast Cells, Phenotype, Irritable Bowel Syndrome
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