Long term follow up of radiofrequency catheter ablation of atrial flutter: clinical course and predictors of atrial fibrillation occurrence
Open accessAbstract
OBJECTIVES: To evaluate the time to onset and the predictors of atrial fibrillation (AF) during long term follow up of patients with typical atrial flutter (AFL) treated with transisthmic ablation. DESIGN: Prospective multicentre study. METHODS AND RESULTS: 383 patients (75.4% men, mean (SD) age 61.7 (11.1) years) who underwent transisthmic ablation for typical AFL were investigated. In 239 patients (62.4%) AF was present before ablation. Ablation proved successful in 367 patients (95.8%). During a mean (SD) follow up of 20.5 (12.4) months, 41.5% of patients reported AF. The cumulative probability of postablation AF increased continuously as time passed: it was 22% at six months, 36% at one year, 50% at two years, 58% at three years, and 63% at four years. CONCLUSIONS: AF occurred in a large proportion of patients after transisthmic catheter ablation of typical AFL. The occurrence of AF was progressive during follow up. Preablation AF, age < 65 years, and left atrial size > 50 mm are associated with postablation AF occurrence.
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Many patients diagnosed with atrial flutter develop AF.
“Furthermore, many patients diagnosed with atrial flutter develop AF. [993][994][995]”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [993]
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- Authors
- Bertaglia, E., Zoppo, F., Bonso, A., Proclemer, A., Verlato, R., Corò, L., Mantovan, R., D’Este, D., Zerbo, F., & Pascotto, P.
- Affiliations
- Ospedale di Mirano (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Ca' Foncello Hospital (IT)
- Corresponding author
- Bertaglia, E
- ORCID
- Bertaglia, E
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2003-12-15
- Volume
- 90
- Issue
- 1
- Pages
- 59-63
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- PMC
- PMC1768035
- OpenAlex
- W2170479933
- Cited by
- 88
- References
- 32
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 5 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 10 · 2015: 5 · 2014: 11 · 2013: 4 · 2012: 3
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Heart (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- atrial flutter, atrial fibrillation, radiofrequency catheter ablation, predictors of atrial fibrillation, left atrial size, age, long-term follow-up
- MeSH terms
- Atrial Fibrillation, Atrial Flutter, Electrocardiography, Female, Follow-Up Studies, Humans, Male, Middle Aged, Postoperative Complications, Prospective Studies, Recurrence, Time Factors, Catheter Ablation, Disease-Free Survival
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