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Cited by 57Obstructive Sleep Apnea ResearchSleep and related disordersTemporomandibular Joint Disorders

Independent validation of the Sleep Apnoea Quality of Life Index

Open access
Lacasse, Y·2002·Thorax
DOI 10.1136/thorax.57.6.483PMC PMC1746356
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Abstract

BACKGROUND: Obstructive sleep apnoea (OSA) affects important domains of quality of life which remain unexplored by conventional sleep recordings. The objective of this study was to examine the measurement properties (both discriminative and evaluative) of the Sleep Apnoea Quality of Life Index (SAQLI), a new OSA specific quality of life questionnaire. METHODS: Consecutive patients recently diagnosed with OSA completed a French version of the SAQLI twice over a 3 month period. Its construct validity and responsiveness were tested by comparing baseline and change scores obtained in each domain (symptoms, activities, emotions, social interactions) with those of questionnaires measuring related constructs (SF-36, Epworth Scale, Beck Depression Inventory, and Symptom Checklist 90). The symptoms scores were also correlated with physiological measures obtained at baseline polysomnographic recording. RESULTS: Forty seven patients (40 men) of mean (SD) age 53 (10) years and mean (SD) apnoea/hypopnoea index 38 (21) participated in the study. During the study period 33 of the 47 patients were treated for OSA (31 with nasal CPAP, one with uvulopalatopharyngoplasty, and one with an oral appliance). Moderate to high correlations were found between the scores in each domain of the SAQLI and the corresponding instruments. There were significant differences in change scores between patients who were treated and those who were not, moderate correlations between SAQLI change scores and changes in the corresponding instruments, and no correlation between the symptoms scores and the baseline nocturnal features. Most of these correlations met the a priori predictions made regarding their magnitude. CONCLUSION: The SAQLI has strong construct validity and is responsive to change in quality of life but has the disadvantage of having to be administered by an interviewer.

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Crossref · 10.1136/thorax.57.6.483

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  • Validated functional status and quality-of-life measures most used in clinical and research settings include the ESS, SAQLI, FOSQ, and PSQI.

    “Validated functional status and QOL measures most used in the clinical and research settings include the ESS,436 Sleep Apnea Quality of Life Index (SAQLI),437–441 Functional Outcomes of Sleep Questionnaire (FOSQ),437,441,442 and the Pittsburgh Sleep Quality Index (PSQI).443”

    From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [440]

    The SAQLI and Discriminative properties sections describe the SAQLI as an obstructive-sleep-apnoea quality-of-life measure and report evidence for its validity. The introduction mentions the FOSQ as an emerging sleep-specific questionnaire, but this paper does not validate it or establish that these measures are among the most used in clinical and research settings. The cited paper’s contribution therefore supports the SAQLI portion, not the full claim. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

  • The FOSQ and SAQLI demonstrated excellent internal consistency (α ≥ 0.9).

    “while the FOSQ and SAQLI demonstrated excellent internal consistency (α ≥ 0.9).437,438,440,442”

    From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [440]

    The Reliability and internal consistency section (page not specified) reports SAQLI Cronbach’s alpha values of 0.94, 0.90, and 0.93 for three domains. The paper mentions the FOSQ but does not report its internal consistency, so it supports only the SAQLI part of the claim. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

  • The SAQLI includes 35 questions across four domains: daily functioning, social interactions, emotional functioning, and symptoms, and can be combined with a fifth domain assessing negative treatment impacts.

    “The SAQLI includes 35 questions across four domains: daily functioning, social interactions, emotional functioning, and symptoms and can be combined with a fifth domain that assesses negative impacts of treatment.”

    From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [440]

    The SAQLI section (page not specified) describes a 35-item questionnaire with the four named core domains. Our copy does not describe an optional fifth domain assessing negative treatment impacts, so that part of the claim is unsupported. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

  • The SAQLI and FOSQ both demonstrated the ability to detect change over time after treatment initiation.

    “The SAQLI and FOSQ both demonstrated the ability to detect change over time after treatment initiation.”

    From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [440]

    The Discussion reports that the SAQLI detected changes in quality of life over three months among patients receiving OSA-specific treatment. The Evaluative properties section compares the SAQLI with the SF-36, not the FOSQ; the retrieved passages do not support the FOSQ part of the claim. Page numbers were not supplied in our copy. (LLM, conf=0.90)

    Experimental — accuracy not yet measured

  • The SAQLI showed moderate correlations (0.3 ≤ r < 0.7) with related domains of general health-status questionnaires such as SF-36 and the Global QOL Scale.

    “The SAQLI showed moderate correlations (0.3 ≤ r < 0.7) with related domains of general health-status questionnaires such as the 36-item Short Form (SF-36) and the Global QOL Scale.”

    From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [440]

    The Discriminative properties section reports good correlations between the SAQLI and related measures. Table 4 reports several moderate correlations with SF-36 domains and a global rating of change, but its SF-36 vitality correlations are 0.76 and 0.88—above the claimed range. The paper calls the global measure a rating of change, not a “Global QOL Scale.” (LLM, conf=0.88)

    Experimental — accuracy not yet measured

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Cites

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Research works printed but not linked: 2

  1. [15]15. Derogatis LR, Cleary PA. Confirmation of the dimensional structure of the SCL-90: a study in construct validity. J Clin Psychol 1977;33:981-9.
  2. [27]27. Flemons WW, Reimer MA. The Calgary sleep apnea quality of life index: determining the minimal important difference. Am J Respir Crit Care Med 1999;159:A769.

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Authors
Lacasse, Y.
Affiliations
Institut universitaire de cardiologie et de pneumologie de Québec (CA)
Corresponding author
Lacasse, Y
ORCID
Lacasse, Y
Venue
Thorax
Publisher
BMJ
Published
2002-06-01
Volume
57
Issue
6
Pages
483-488
ISSN
0040-6376 (ISSN-L)
DOI
10.1136/thorax.57.6.483
PMC
PMC1746356
OpenAlex
W2129468836
Semantic Scholar
ef98ef2cdaf81e5002a794c0d644f98318155c32
Cited by
57
References
33
Citations by year
2026: 1 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 4 · 2018: 1 · 2017: 5 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 3 · 2012: 4
FWCI
3.19
Type
journal article
Language
en
Open access
Locations
  • Thorax (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
Keywords
obstructive sleep apnea, quality of life, construct validity, responsiveness to change, questionnaire validation, French adaptation, CPAP therapy, polysomnography, SF-36, Epworth Sleepiness Scale, Beck Depression Inventory, SCL-90
MeSH terms
Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Sleep Apnea Syndromes, Reproducibility of Results

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