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Cited by 28Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and LipoproteinsCardiovascular and exercise physiology

Exercise, postprandial triacylglyceridemia, and cardiovascular disease risk.

Graham, Terry E.·2004·Canadian Journal of Applied Physiology
DOI 10.1139/h04-051
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Abstract

An elevation of plasma triacylglycerides (TAG) is a well recognized cardiovascular risk factor. Less appreciated is that high and prolonged elevations in TAG in the postprandial (PP) phase is also a risk factor. Given that we spend approximately 18 hrs a day in the PP state, this is particularly critical. The elevation is due to both cylomicron and very low density lipoprotein TAG. It is thought that enhancing the concentrations of these lipoproprotein fractions increases the production of smaller, more dense low density lipoprotein and that this leads to increased cardiovascular disease risk. The PP TAG response is greater in men, in obese individuals, and in type 2 diabetics. It has been reported repeatedly that exercise the day before ingestion of a high fat meal is associated with a marked dampening of the PP TAG rise. The mechanisms for this are not clear and do not appear to be due to changes in the exercised muscle itself. There is some speculation that the production of plasma TAG may be decreased. The exercise benefits are lost within 3 days. The minimum exercise required has not been determined, but even 30 min of intermittent aerobic exercise or mild resistance exercise has a positive effect. This demonstrates a clear benefit from an active lifestyle and one that does not require intense exercise or months of training.

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Crossref · 10.1139/h04-051

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52 of 52 references verified0 citation errors · 0 not checkable

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  • Exercise the day before ingestion of a high-fat meal is associated with a marked dampening of the postprandial triglyceride increase.

    “It has been reported that exercise the day before ingestion of a high-fat meal is associated with a marked dampening of the postprandial triglyceride increase.”

    From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [158]

  • A period of 30-60 min of intermittent aerobic exercise or mild resistance exercise has been shown to be effective in lowering plasma and VLDL triglycerides.

    “The minimum exercise required to reduce a postprandial triglyceride increase has not been determined, but a period of 30 -60 min of intermittent aerobic exercise or mild resistance exercise has been shown to be effective in lowering plasma and VLDL triglycerides.”

    From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [158]

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Authors
Graham, T. E.
Affiliations
University of Guelph (CA)
Corresponding author
Graham, Terry E.
Venue
Canadian Journal of Applied Physiology
Publisher
Canadian Science Publishing
Published
2004-12-01
Volume
29
Issue
6
Pages
781-799
ISSN
1066-7814 (ISSN-L)
DOI
10.1139/h04-051
OpenAlex
W2063017415
Cited by
28
References
52
Citations by year
2022: 1 · 2020: 1 · 2017: 1 · 2016: 5 · 2015: 2 · 2014: 5 · 2013: 3 · 2012: 2
FWCI
0.29
Type
journal article
Language
en
Open access
closed
Licence
www.nrcresearchpress.com/page/about/CorporateTextAndDataMining (tdm)
Locations
  • Canadian Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
physical activity, cardiovascular risk, VLDL, chylomicrons, low-density lipoprotein, high-fat meal, obesity, type 2 diabetes, sex differences, aerobic exercise, resistance training
MeSH terms
Cardiovascular Diseases, Diabetes Mellitus, Type 2, Female, Humans, Life Style, Male, Obesity, Risk Factors, Sex Characteristics, Triglycerides, Exercise, Postprandial Period

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