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Cited by 365

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Etiology of Exercise-Induced Muscle Damage

Clarkson, Priscilla M., Sayers, Stephen P.·1999·Canadian Journal of Applied Physiology
DOI 10.1139/h99-020
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Abstract

Muscle damage is caused by strenuous and unaccustomed exercise, especially exercise involving eccentric muscle contractions, where muscles lengthen as they exert force. Damage can be observed both directly at the cellular level and indirectly from changes in various indices of muscle function. Several mechanisms have been offered to explain the etiology of the damage/repair process, including mechanical factors such as tension and strain, disturbances in calcium homeostasis. the inflammatory response, and the synthesis of stress proteins (heat shock proteins). Changes in muscle function following eccentric exercise have been observed at the cellular level as an impairment in the amount and action of transport proteins for glucose and lactate/H+, and at the systems level as an increase in muscle stiffness and a prolonged loss in the muscle's ability to generate force. This paper will briefly review factors involved in the damage/repair process and alterations in muscle function following eccentric exercise. Key words: eccentric exercise, inflammation, stress proteins, muscle function

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Metadata

Authors
Clarkson, P. M., & Sayers, S. P.
Venue
Canadian Journal of Applied Physiology
Publisher
Canadian Science Publishing
Published
1999-06-01
Volume
24
Issue
3
Pages
234-248
ISSN
1066-7814 (ISSN-L)
DOI
10.1139/h99-020
OpenAlex
W2081951179
Cited by
365
References
6
FWCI
11.10
Type
journal article
Language
en
Open access
closed

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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