Cited by 30Attention Deficit Hyperactivity DisorderNeural and Behavioral Psychology StudiesDevelopmental and Educational Neuropsychology

Distractibility in AD/HD predominantly inattentive and combined subtypes: the P3a ERP component, heart rate and performance

KEAGE, HANNAH A. D., CLARK, C. RICHARD, HERMENS, DANIEL F., KOHN, MICHAEL R., CLARKE, SIMON, WILLIAMS, LEANNE M., CREWTHER, DAVID, LAMB, CHRIS +1 more·2006·Journal of Integrative Neuroscience

Abstract

The current study aimed to investigate whether children and adolescents diagnosed with Attention Deficit/Hyperactivity Disorder Predominantly Inattentive (AD/HD-in; Child n = 24, Adolescent n = 33) and Combined (AD/HD-com; Child n = 30, Adolescent n = 42) subtypes were more distractible than controls (Child n = 54; Adolescents n = 75), by assessing event-related potential (ERP), performance and peripheral arousal measures. All AD/HD groups displayed smaller amplitudes and/or shorter latencies of the P3a ERP component - thought to reflect involuntary attention switching - following task-deviant novel stimuli (checkerboard patterns) embedded in a Working Memory (WM) task. The P3a results suggested that both AD/HD-in and AD/HD-com subtypes ineffectively evaluate deviant stimuli and are hence more "distractible". These abnormalities were most pronounced over the central areas. AD/HD groups did not display any abnormalities in averaged heart rate over the WM task, a measure of peripheral arousal. They did display abnormalities in performance measures from the task, but these were unrelated to P3a abnormalities. AD/HD groups also displayed a number of deficits on Switching of Attention and Verbal Memory tasks, however, the pattern of abnormality mostly reflected general cognitive deficits rather than resulting from distraction.

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Crossref · 10.1142/s0219635206001070

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Authors
KEAGE, H. A. D., CLARK, C. R., HERMENS, D. F., KOHN, M. R., CLARKE, S., WILLIAMS, L. M., CREWTHER, D., LAMB, C., & GORDON, E.
Affiliations
  • Flinders University (AU)
  • The University of Sydney (AU)
  • Swinburne University of Technology (AU)
  • Flinders Medical Centre (AU)
Corresponding author
CLARK, C. RICHARD
Venue
Journal of Integrative Neuroscience
Published
2006-03
Volume
05
Issue
01
Pages
139-158
ISSN
  • 0219-6352 (ISSN-L)
  • 1757-448X
OpenAlex
W2088277621
Cited by
30
References
71
Citations by year
2025: 1 · 2023: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 4 · 2012: 2
FWCI
1.49
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Integrative Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • Flinders Academic Commons (Flinders University) (submittedVersion)
  • Swinburne figshare (Swinburne University of Technology) (submittedVersion)
Funders
Australian Research Council
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
Keywords
attention deficit hyperactivity disorder, inattentive subtype, combined subtype, distractibility, event-related potentials, heart rate, working memory, attentional shift, verbal memory, children and adolescents
MeSH terms
Adolescent, Analysis of Variance, Attention, Attention Deficit Disorder with Hyperactivity, Brain Neoplasms, Child, Electroencephalography, Evoked Potentials, Auditory, Female, Heart Rate, Humans, Male, Memory, Short-Term, Neuropsychological Tests, Psychomotor Performance, Reaction Time, Verbal Learning

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