Distractibility in AD/HD predominantly inattentive and combined subtypes: the P3a ERP component, heart rate and performance
Abstract
The current study aimed to investigate whether children and adolescents diagnosed with Attention Deficit/Hyperactivity Disorder Predominantly Inattentive (AD/HD-in; Child n = 24, Adolescent n = 33) and Combined (AD/HD-com; Child n = 30, Adolescent n = 42) subtypes were more distractible than controls (Child n = 54; Adolescents n = 75), by assessing event-related potential (ERP), performance and peripheral arousal measures. All AD/HD groups displayed smaller amplitudes and/or shorter latencies of the P3a ERP component - thought to reflect involuntary attention switching - following task-deviant novel stimuli (checkerboard patterns) embedded in a Working Memory (WM) task. The P3a results suggested that both AD/HD-in and AD/HD-com subtypes ineffectively evaluate deviant stimuli and are hence more "distractible". These abnormalities were most pronounced over the central areas. AD/HD groups did not display any abnormalities in averaged heart rate over the WM task, a measure of peripheral arousal. They did display abnormalities in performance measures from the task, but these were unrelated to P3a abnormalities. AD/HD groups also displayed a number of deficits on Switching of Attention and Verbal Memory tasks, however, the pattern of abnormality mostly reflected general cognitive deficits rather than resulting from distraction.
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Keage et al. (2006) found no HR differences between groups.
“In a study designed to measure HR and electrophysiological responses (P3a amplitude and latency) to distractor stimuli in a working memory task, Keage et al. (2006), found no HR differences between groups.”
From Is autonomic nervous system function atypical in Attention Deficit Hyperactivity Disorder (ADHD)? A systematic review of the evidence (2020) · cites this paper as Keage et al., 2006
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- Authors
- KEAGE, H. A. D., CLARK, C. R., HERMENS, D. F., KOHN, M. R., CLARKE, S., WILLIAMS, L. M., CREWTHER, D., LAMB, C., & GORDON, E.
- Affiliations
- Flinders University (AU)
- The University of Sydney (AU)
- Swinburne University of Technology (AU)
- Flinders Medical Centre (AU)
- Corresponding author
- CLARK, C. RICHARD
- ORCID
- Venue
- Journal of Integrative Neuroscience
- Publisher
- World Scientific Pub Co Pte Lt
- Published
- 2006-03
- Volume
- 05
- Issue
- 01
- Pages
- 139-158
- ISSN
- 0219-6352 (ISSN-L)
- 1757-448X
- OpenAlex
- W2088277621
- Cited by
- 30
- References
- 71
- Citations by year
- 2025: 1 · 2023: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 4 · 2012: 2
- FWCI
- 1.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Integrative Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Flinders Academic Commons (Flinders University) (submittedVersion)
- Swinburne figshare (Swinburne University of Technology) (submittedVersion)
- Funders
- Australian Research Council
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Keywords
- attention deficit hyperactivity disorder, inattentive subtype, combined subtype, distractibility, event-related potentials, heart rate, working memory, attentional shift, verbal memory, children and adolescents
- MeSH terms
- Adolescent, Analysis of Variance, Attention, Attention Deficit Disorder with Hyperactivity, Brain Neoplasms, Child, Electroencephalography, Evoked Potentials, Auditory, Female, Heart Rate, Humans, Male, Memory, Short-Term, Neuropsychological Tests, Psychomotor Performance, Reaction Time, Verbal Learning
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