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A Comprehensive Overview of Large Language Models
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Large Language Models (LLMs) have recently demonstrated remarkable capabilities in natural language processing tasks and beyond. This success of LLMs has led to a large influx of research contributions in this direction. These works encompass diverse topics such as architectural innovations, better training strategies, context length improvements, fine-tuning, multimodal LLMs, robotics, datasets, benchmarking, efficiency, and more. With the rapid development of techniques and regular breakthroughs in LLM research, it has become considerably challenging to perceive the bigger picture of the advances in this direction. Considering the rapidly emerging plethora of literature on LLMs, it is imperative that the research community is able to benefit from a concise yet comprehensive overview of the recent developments in this field. This article provides an overview of the literature on a broad range of LLM-related concepts. Our self-contained comprehensive overview of LLMs discusses relevant background concepts along with covering the advanced topics at the frontier of research in LLMs. This review article is intended to provide not only a systematic survey but also a quick, comprehensive reference for the researchers and practitioners to draw insights from extensive, informative summaries of the existing works to advance the LLM research.
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“Indeed, LLMs are large (Bender et al., 2021; for a detailed comparison of the number of parameters, see Naveed et al., 2025) and transform text 4 well; however, one must be careful not to demand too much from them.”
From There is no such thing as conscious artificial intelligence (2025) · cites this paper as Naveed et al., 2025
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BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding
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PyTorch: An Imperative Style, High-Performance Deep Learning Library
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Language Models are Few-Shot Learners
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LoRA: Low-Rank Adaptation of Large Language Models
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Deep Contextualized Word Representations
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Lieberum, J.-L., Toews, M., Metzendorf, M.-I., Heilmeyer, F., Siemens, W., Haverkamp, C., Böhringer, D., Meerpohl, J. J., & Eisele-Metzger, A. (2025) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2025.111746 · Cited by 148
Generative Artificial Intelligence in Education: Advancing Adaptive and Personalized Learning
Guettala, M., Bourekkache, S., Kazar, O., & Harous, S. (2024) · Acta Informatica Pragensia · doi:10.18267/j.aip.235 · Cited by 218
From text to insight: large language models for chemical data extraction
Schilling-Wilhelmi, M., Ríos-García, M., Shabih, S., Gil, M. V., Miret, S., Koch, C. T., Marquez, J. A., & Jablonka, K. M. (2024) · Chemical Society Reviews · doi:10.1039/d4cs00913d · Cited by 178
Large language models for reticular chemistry
Zheng, Z., Rampal, N., Inizan, T. J., Borgs, C., Chayes, J. T., & Yaghi, O. M. (2025) · Nature Reviews Materials · doi:10.1038/s41578-025-00772-8 · Cited by 134
Large Language Models for UAVs: Current State and Pathways to the Future
Javaid, S., Fahim, H., He, B., & Saeed, N. (2024) · IEEE Open Journal of Vehicular Technology · doi:10.1109/ojvt.2024.3446799 · Cited by 170
Revolutionizing Health Care: The Transformative Impact of Large Language Models in Medicine
Zhang, K., Meng, X., Yan, X., Ji, J., Liu, J., Xu, H., Zhang, H., Liu, D., Wang, J., Wang, X., et al. (2024) · Journal of Medical Internet Research · doi:10.2196/59069 · Cited by 148
Large Language Model Assisted Software Engineering: Prospects, Challenges, and a Case Study
Belzner, L., Gabor, T., & Wirsing, M. (2023) · Lecture notes in computer science · doi:10.1007/978-3-031-46002-9_23 · Cited by 130
A survey of multilingual large language models
Qin, L., Chen, Q., Zhou, Y., Zhi, C., Li, Y., Liao, L., Li, M., Che, W., & Yu, P. S. (2025) · Patterns · doi:10.1016/j.patter.2024.101118 · Cited by 282
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Evolution and Prospects of Foundation Models: From Large Language Models to Large Multimodal Models
Chen, Z., Xu, L., Zheng, H., Chen, L., Tolba, A. K. R., Zhao, L., Yu, K., & Feng, H. (2024) · Computers, materials & continua/Computers, materials & continua (Print) · doi:10.32604/cmc.2024.052618 · Cited by 126
Roles and potential of Large language models in healthcare: A comprehensive review
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Thinking in Space: How Multimodal Large Language Models See, Remember, and Recall Spaces
Yang, J., Yang, S., Gupta, A. W., Han, R., Fei-Fei, L., & Xie, S. (2025) · 2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr52734.2025.00994 · Cited by 120
“While Large Language Models (LLMs) [3, 6, 9, 36, 61, 67, 68, 77, 81, 82, 88, 105] have advanced linguistic intelligence, visual-spatial intelligence remains under-explored, despite its relevance to robotics [7, 8, 21, 64], autonomous driving [79], and AR/VR [12, 27, 55].”
Integrating LLMs With ITS: Recent Advances, Potentials, Challenges, and Future Directions
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Large Language Models in Cybersecurity: State-of-the-Art
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“Xuan Yuan 2.0, a Chinese financial chat model [59, 97], AlexaTM [80], PaLM-2 [5], as well as GLM-130B [96] are a few instances of general purpose pre-trained LLMs.”
InfluentialLarge language models in food science: Innovations, applications, and future
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UAVs meet LLMs: Overviews and perspectives towards agentic low-altitude mobility
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On protecting the data privacy of Large Language Models (LLMs) and LLM agents: A literature review
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A review of AI edge devices and lightweight CNN and LLM deployment
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Large language models for life cycle assessments: Opportunities, challenges, and risks
Preuss, N., Alshehri, A. S., & You, F. (2024) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2024.142824 · Cited by 71
Text clustering with large language model embeddings
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Multi-Modal LLMs in Agriculture: A Comprehensive Review
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Beyond Traditional Assessment: Exploring the Impact of Large Language Models on Grading Practices
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Introduction to large language models (LLMs) for dementia care and research
Treder, M. S., Lee, S., & Tsvetanov, K. A. (2024) · Frontiers in Dementia · doi:10.3389/frdem.2024.1385303 · Cited by 63
A review of LLMs and their applications in the architecture, engineering and construction industry
Kampelopoulos, D., Tsanousa, A., Vrochidis, S., & Kompatsiaris, I. (2025) · Artificial Intelligence Review · doi:10.1007/s10462-025-11241-7 · Cited by 69
Large language models reduce public knowledge sharing on online Q&A platforms
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Are Large Language Models a Threat to Digital Public Goods? Evidence from Activity on Stack Overflow
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A guide to prompt design: foundations and applications for healthcare simulationists
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El Agente: An autonomous agent for quantum chemistry
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Natural Language Processing for Dialects of a Language: A Survey
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Contextual feature extraction hierarchies converge in large language models and the brain
Mischler, G., Li, Y. A., Bickel, S., Mehta, A. D., & Mesgarani, N. (2024) · Nature Machine Intelligence · doi:10.1038/s42256-024-00925-4 · Cited by 70
Conversing with business process-aware large language models: the BPLLM framework
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Schlosser, L., Rana, D., Pflüger, P. M., Katzenburg, F., & Glorius, F. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c01352 · Cited by 50
A Survey on Hybrid-CNN and LLMs for Intrusion Detection Systems: Recent IoT Datasets
Elouardi, S., Motii, A., Jouhari, M., Amadou, A. N. H., & Hedabou, M. (2024) · IEEE Access · doi:10.1109/access.2024.3506604 · Cited by 43
Generative AI as a tool to accelerate the field of ecology
Rafiq, K., Beery, S., Palmer, M. S., Harchaoui, Z., & Abrahms, B. L. (2025) · Nature Ecology & Evolution · doi:10.1038/s41559-024-02623-1 · Cited by 49
Leveraging Large Language Models for Intelligent Control of 6G Integrated TN-NTN With IoT Service
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Artificial intelligence in rheumatology research: what is it good for?
Sequí-Sabater, J. M., & Benavent, D. (2025) · RMD Open · doi:10.1136/rmdopen-2024-004309 · Cited by 43
CE-CoLLM: Efficient and Adaptive Large Language Models Through Cloud-Edge Collaboration
Jin, H., & Wu, Y. (2025) · IEEE International Conference on Web Services (ICWS) · doi:10.1109/icws67624.2025.00046 · Cited by 39
Sevgi, M., Antaki, F., & Keane, P. A. (2024) · British Journal of Ophthalmology · doi:10.1136/bjo-2023-325046 · Cited by 42
Large language models "ad referendum": How good are they at machine translation in the legal domain?
Brivá-Iglesias, V., Doğru, G., & Camargo, J. L. C. (2024) · MonTi Monografías de Traducción e Interpretación · doi:10.6035/monti.2024.16.02 · Cited by 83
Cook, A., & Karakuş, O. (2024) · Knowledge-Based Systems · doi:10.1016/j.knosys.2024.112219 · Cited by 42
A Comprehensive Overview and Analysis of Large Language Models: Trends and Challenges
Mohammed, A., & Kora, R. (2025) · IEEE Access · doi:10.1109/access.2025.3573955 · Cited by 45
Remote Sensing Spatiotemporal Vision–Language Models: A comprehensive survey
Liu, C., Zhang, J. Q., Chen, K., Wang, M., Zou, Z., & Shi, Z. (2025) · IEEE Geoscience and Remote Sensing Magazine · doi:10.1109/mgrs.2025.3598283 · Cited by 54
Khadija, M. A., Aziz, A., & Nurharjadmo, W. (2023) · International Conference on Computer, Control, Informatics and its Applications · doi:10.1109/ic3ina60834.2023.10285808 · Cited by 36
A survey on deep learning-based algorithms for the traveling salesman problem
Sui, J., Ding, S., Huang, X., Yu, Y., Liu, R., Xia, B., Ding, Z., Xu, L., Zhang, H., Yu, C., et al. (2024) · Frontiers of Computer Science · doi:10.1007/s11704-024-40490-y · Cited by 43
Navigating the Ethical Terrain of AI-Generated Text Tools: A Review
Mohamed, Y. A., Mohamed, A. H. H. M., Khanan, A., Bashir, M., Adiel, M. A. E., & Elsadig, M. A. (2024) · IEEE Access · doi:10.1109/access.2024.3521945 · Cited by 44
Automatic Construction Accident Report Analysis Using Large Language Models (LLMs)
Ahmadi, E., Muley, S., & Wang, C. (2025) · Journal of Intelligent Construction · doi:10.26599/jic.2024.9180039 · Cited by 35
Linardon, J., Jarman, H. K., McClure, Z., Anderson, C., Liu, C., & Messer, M. (2025) · JMIR Mental Health · doi:10.2196/80371 · Cited by 40
Evidence-Based Learning Strategies in Medicine Using AI
Arango-Ibañez, J. P., Posso-Nuñez, J. A., Díaz-Solórzano, J. P., & Cruz, G. (2024) · JMIR Medical Education · doi:10.2196/54507 · Cited by 43
Pashangpour, S., & Nejat, G. (2024) · Robotics · doi:10.3390/robotics13080112 · Cited by 42
Meshkin, H., Zirkle, J., Arabidarrehdor, G., Chaturbedi, A., Chakravartula, S., Mann, J., Thrasher, B., & Li, Z. (2024) · Briefings in Bioinformatics · doi:10.1093/bib/bbae354 · Cited by 41
Rungruangjit, W., Mongkol, K., Piriyakul, I., & Charoenpornpanichkul, K. (2024) · Computers in Human Behavior Reports · doi:10.1016/j.chbr.2024.100523 · Cited by 55
Advancing depression detection on social media platforms through fine-tuned large language models
Shah, S. M., Gillani, S. A., Baig, M. R., Saleem, M. A., & Siddiqui, M. (2025) · Online Social Networks and Media · doi:10.1016/j.osnem.2025.100311 · Cited by 34
Zsidai, B., Kaarre, J., Narup, E., Senorski, E. H., Pareek, A., Grassi, A., Ley, C., Longo, U. G., Herbst, E., Hirschmann, M. T., et al. (2024) · Journal of Experimental Orthopaedics · doi:10.1002/jeo2.12025 · Cited by 33
Failure Management Overview in Optical Networks
Cruzes, S. (2024) · IEEE Access · doi:10.1109/access.2024.3498704 · Cited by 41
Warr, M., & Heath, M. K. (2025) · Journal of Teacher Education · doi:10.1177/00224871251325073 · Cited by 35
Knowledge graph construction for heart failure using large language models with prompt engineering
Xu, T., Gu, Y., Xue, M., Gu, R., Li, B., & Gu, X. (2024) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2024.1389475 · Cited by 35
The Evolution of Large Language Model: Models, Applications and Challenges
Sindhu, B., Prathamesh, R. P., Sameera, M. B., & Kumaraswamy, S. (2024) · International Conference on Current Trends in Advanced Computing (ICCTAC) · doi:10.1109/icctac61556.2024.10581180 · Cited by 41
Deep Representation Learning: Fundamentals, Technologies, Applications, and Open Challenges
Payandeh, A., Baghaei, K. T., Fayyazsanavi, P., Ramezani, S. B., Chen, Z., & Rahimi, S. (2023) · IEEE Access · doi:10.1109/access.2023.3335196 · Cited by 49
On future power system digital twins: A vision towards a standard architecture
Zomerdijk, W., Pálenský, P., AlSkaif, T. A., & Vergara, P. P. (2024) · Digital twins and applications. · doi:10.1049/dgt2.12020 · Cited by 35
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Setälä, M., Heilala, V., Sikström, P., & Kärkkäinen, T. (2025) · ACM Symposium on Applied Computing · doi:10.1145/3672608.3707817 · Cited by 51
Abu-Rasheed, H., Jumbo, C., Amin, R. A., Weber, C., Wiese, V., Obermaisser, R., & Fathi, M. (2025) · IEEE Global Engineering Education Conference (EDUCON) · doi:10.1109/educon62633.2025.11016377 · Cited by 30
Object detection with multimodal large vision-language models: An in-depth review
Sapkota, R., & Karkee, M. (2025) · Information Fusion · doi:10.1016/j.inffus.2025.103575 · Cited by 61
Making the case for introducing generative artificial intelligence (AI) into design curricula
Fleischmann, K. (2024) · Art Design & Communication in Higher Education · doi:10.1386/adch_00088_1 · Cited by 29
Sun, Z., Hong, W., Xue, C., & Dong, N. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.175971 · Cited by 31
McLean, A. L., & Hristidis, V. (2025) · Journal of Cancer Education · doi:10.1007/s13187-025-02592-4 · Cited by 29
Kozlowski, A. C., & Evans, J. A. (2025) · Sociological Methods & Research · doi:10.1177/00491241251337316 · Cited by 49
Banad, Y. M., Sharifi, S., & Rezaei, Z. (2025) · Energy Conversion and Management X · doi:10.1016/j.ecmx.2025.101329 · Cited by 45
Benchmark Evaluations, Applications, and Challenges of Large Vision Language Models: A SurveyPreprint
Li, Z., Wu, X., Du, H., Nghiem, H. T., & Shi, G. (2025) · Qeios · doi:10.32388/gxr68q · Cited by 33
Photonic probabilistic machine learning using quantum vacuum noise
Choi, S., Salamin, Y., Roques‐Carmes, C., Dangovski, R., Luo, D., Chen, Z., Horodynski, M., Sloan, J., Uddin, S. Z., & Marin Soljacic, A. (2024) · Nature Communications · doi:10.1038/s41467-024-51509-0 · Cited by 32
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Yang, H., Hu, M., Most, A. K., Hawkins, W. A., Murray, B., Smith, S. E., Li, S., & Sikora, A. N. (2025) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2024.1514896 · Cited by 28
Agentic AI Security: Threats, Defenses, Evaluation, and Open Challenges
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“• Personalized support: When equipped with memory and adaptive reasoning, agentic systems can function as persistent digital concierges that track user preferences over time.”
Kholodna, N., Julka, S., Khodadadi, M., Gumus, M. N., & Granitzer, M. (2024) · Lecture notes in computer science · doi:10.1007/978-3-031-70381-2_25 · Cited by 40
SeedLLM·Rice: A large language model integrated with rice biological knowledge graph
Yang, F., Kong, H., Ying, J., Chen, Z., Luo, T., Jiang, W., Yuan, Z., Wang, Z., Ma, Z., Wang, S., et al. (2025) · Molecular Plant · doi:10.1016/j.molp.2025.05.013 · Cited by 29
Prompt engineering for accurate statistical reasoning with large language models in medical research
Vilakati, S. (2025) · Frontiers in Artificial Intelligence · doi:10.3389/frai.2025.1658316 · Cited by 30
LLMs in Cyber Security: Bridging Practice and Education
Atlam, H. F. (2025) · Big Data and Cognitive Computing · doi:10.3390/bdcc9070184 · Cited by 27
SCAR: Power Side-Channel Analysis at RTL Level
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Streamlining geoscience data analysis with an LLM-driven workflow
Zhang, J., Clairmont, C., Que, X., Li, W., Chen, W., Li, C., & Ma, X. (2024) · Applied Computing and Geosciences · doi:10.1016/j.acags.2024.100218 · Cited by 33
Exploring Embodied Multimodal Large Models: Development, datasets, and future directions
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Capability of multimodal large language models to interpret pediatric radiological images
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Large-scale foundation models and generative AI for BigData neuroscience
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Metadata
- Authors
- Naveed, H., Khan, A. U., Qiu, S., Saqib, M., Anwar, S., Usman, M., Akhtar, N., Barnes, N., & Mian, A.
- Affiliations
- The University of Sydney (AU)
- University of Engineering and Technology Lahore (PK)
- Chinese University of Hong Kong (HK)
- University of Technology Sydney (AU)
- King Fahd University of Petroleum and Minerals (SA)
- Ontario Tech University (CA)
- The University of Melbourne (AU)
- Australian National University (AU)
- The University of Western Australia (AU)
- ORCID
- Venue
- ACM Transactions on Intelligent Systems and Technology
- Published
- 2025-08-18
- Volume
- 16
- Issue
- 5
- Pages
- 1-72
- ISSN
- 2157-6904 (ISSN-L)
- 2157-6912
- OpenAlex
- W4411403346
- Cited by
- 1,257
- References
- 245
- Citations by year
- 2026: 527 · 2025: 488
- FWCI
- 407.12
- Type
- journal article
- Language
- en
- Open access
- green
- arxiv.org
- Licence
- cc-by
- Locations
- ACM Transactions on Intelligent Systems and Technology (publishedVersion)
- arXiv (Cornell University) (submittedVersion, cc-by)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- arXiv (Cornell University) (cc-by)
- Funders
- King Fahd University of Petroleum and Minerals
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
- Physical Sciences › Computer Science › Artificial Intelligence › Natural Language Processing Techniques
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
- Keywords
- large language models, LLM architecture, context length, fine-tuning, multimodal large language models, LLM benchmarking
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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