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Cited by 400

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Nuclear Actin and Actin-Related Proteins in Chromatin Remodeling

Olave, Ivan A., Reck-Peterson, Samara L., Crabtree, Gerald R.·2002·Annual Review of Biochemistry

Abstract

▪ Abstract The existence and function of actin in the nucleus has been hotly debated for forty years. Recently, β-actin was found to be a component of mammalian SWI/SNF-like BAF chromatin remodeling complexes and still more recently other SWI/SNF-related chromatin remodeling complexes in yeast, flies, and man. Although the function of actin in these chromatin remodeling complexes is only starting to be explored, the fact that actin is one of the most regulated proteins in the cell suggests that control of nuclear actin may be a critical regulatory point in the control of chromatin remodeling. Actin rapidly shuttles between the nucleus and the cytoplasm offering additional sites and modes of regulation. In addition, actin-related proteins (Arps) are also components of these chromatin remodeling complexes and have been implicated in transcriptional control in yeast. The observation that the BAF chromatin remodeling complex in which actin was originally identified, is also a human tumor suppressor complex necessary for the actions of the retinoblastoma protein indicates that the study of nuclear actin is likely to contribute to understanding cell growth control.

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Metadata

Authors
Olave, I. A., Reck-Peterson, S. L., & Crabtree, G. R.
Venue
Annual Review of Biochemistry
Published
2002-06
Volume
71
Issue
1
Pages
755-781
ISSN
  • 0066-4154 (ISSN-L)
  • 1545-4509
OpenAlex
W2130873698
Cited by
400
References
4
FWCI
1.93
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Nuclear Actin and Actin-Related Proteins in Chromatin Remodeling. https://app.cochat.ai/papers/10.1146/annurev.biochem.71.110601.135507
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Olave, I. A., Reck-Peterson, S. L., & Crabtree, G. R. (2002). Nuclear Actin and Actin-Related Proteins in Chromatin Remodeling. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.71.110601.135507

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.