The DOI matches its Crossref record; 79 of the 81 references it cites were found in a registry or an index.
Physicochemical Foundations and Structural Design of Hydrogels in Medicine and Biology
Abstract
▪ Abstract Hydrogels are cross-linked hydrophilic polymers that can imbibe water or biological fluids. Their biomedical and pharmaceutical applications include a very wide range of systems and processes that utilize several molecular design characteristics. This review discusses the molecular structure, dynamic behavior, and structural modifications of hydrogels as well as the various applications of these biohydrogels. Recent advances in the preparation of three-dimensional structures with exact chain conformations, as well as tethering of functional groups, allow for the preparation of promising new hydrogels. Meanwhile, intelligent biohydrogels with pH- or temperature-sensitivity continue to be important materials in medical applications.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Hydrophilic surface modifications, such as the PEG modified surfaces discussed above, have also been widely characterized in the literature and have demonstrated excellent anti-adhesive properties for bacteria cells and proteins.44”
From Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO) (2016) · cites this paper as [44]
Citations
Cites
Principles of Polymer Chemistry.
Huggins, M. L. (1954) · Journal of the American Chemical Society · doi:10.1021/ja01639a090 · Cited by 16,658
Principles of polymer chemistry
(1995) · Choice Reviews Online · doi:10.5860/choice.33-2140 · Cited by 15,292
Statistical Mechanics of Cross-Linked Polymer Networks II. Swelling
Flory, P. J., & Rehner, J. (1943) · The Journal of Chemical Physics · doi:10.1063/1.1723792 · Cited by 3,972
Hydrophilic gels for biological use
WICHTERLE, O., & LÍM, D. (1960) · Nature · doi:10.1038/185117a0 · Cited by 2,996
Wulff, G. (1995) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199518121 · Cited by 2,373
Polymerized colloidal crystal hydrogel films as intelligent chemical sensing materials
Holtz, J. H., & Asher, S. A. (1997) · Nature · doi:10.1038/39834 · Cited by 2,003
Comb-type grafted hydrogels with rapid deswelling response to temperature changes
Yoshida, R., Uchida, K., Kaneko, Y., Sakai, K., Kikuchi, A., Sakurai, Y., & Okano, T. (1995) · Nature · doi:10.1038/374240a0 · Cited by 1,257
Graft copolymers that exhibit temperature-induced phase transitions over a wide range of pH
Chen, G., & Hoffman, A. S. (1995) · Nature · doi:10.1038/373049a0 · Cited by 1,221
A reversibly antigen-responsive hydrogel
Miyata, T., Asami, N., & Uragami, T. (1999) · Nature · doi:10.1038/21619 · Cited by 1,175
Tethered chains in polymer microstructures
Halperin, A., Tirrell, M., & Lodge, T. P. (2006) · Springer eBooks · doi:10.1007/bfb0051635 · Cited by 1,139
Flagged first, then by citations
2 of the 81 references couldn’t be matched to a known paper.
Research works printed but not linked: 11
- Lowman AM, Peppas NA. 1999. Hydrogels. In Encyclopedia of Controlled Drug Delivery , ed. E Mathiowitz, pp. 397–418. New York: Wiley
- Peppas NA, 1986, Hydrogels in Medicine and Pharmacy, Vols. 1, 2.
- Andrews AT, 1986, Electrophoresis.
- Chaikof EL, 1996, Chemtech, 26, 17
- Bell CL, 1995, Adv. Polym. Sci., 122, 126
- Okano T, 1998, Biorelated Polymers and Gels.
- Tanaka N, 1989, Adv. Chromatogr., 30, 81
- Peppas NA. 1996. Hydrogels. In Biomaterials Science , ed. BD Ratner, AS Hoffman, FJ Schoen, JE Lemons, pp. 60–64. San Diego, CA: Academic
- Hoffman AS. 1995. Intelligent polymers. In Polymeric Materials Encyclopedia , ed. JC Salamone, pp. 3282–92. Boca Raton, FL: CRC
- Tanaka T, 1996, Faraday Discuss., 102, 201
- Chen J, 1998, Proc. Int. Symp. Control. Release Bioact. Mater., 25, 60
Cited by
Sorted by citations
Items 301–400 of 999
Cabral, J. D., Roxburgh, M., Shi, Z., Liu, L., McConnell, M. A., Williams, G., Evans, N., Hanton, L. R., Simpson, J., Moratti, S. C., et al. (2014) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-014-5292-3 · Cited by 54
Liu, Z., Xiao, L., Xu, B., Zhang, Y., Mak, A. F. T., Li, Y., Man, W.-Y., & Yang, M. (2012) · Biomicrofluidics · doi:10.1063/1.4704522 · Cited by 53
Macromolecular Diffusion in Self-Assembling Biodegradable Thermosensitive Hydrogels
Vermonden, T., Jena, S. S., Barriet, D., Censi, R., van der Gucht, J., Hennink, W. E., & Siegel, R. A. (2009) · Macromolecules · doi:10.1021/ma902186e · Cited by 53
Akhtar, M. F., Ranjha, N. M., & Hanif, M. A. (2015) · DARU Journal of Pharmaceutical Sciences · doi:10.1186/s40199-015-0123-8 · Cited by 54
Farhat, W., Hasan, A., Lucia, L. A., Becquart, F., Ayoub, A. S., & Kobeissy, F. H. (2018) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2018.2824335 · Cited by 53
Huber, T., Feast, S., Dimartino, S., Cen, W., & Fee, C. J. (2019) · Materials · doi:10.3390/ma12071066 · Cited by 53
Kuang, M., Wang, D., & Möhwald, H. (2005) · Advanced Functional Materials · doi:10.1002/adfm.200500141 · Cited by 53
Glucomannan-poly(N-vinyl pyrrolidinone) bicomponent hydrogels for wound healing
Shahbuddin, M., Bullock, A. J., MacNeil, S., & Rimmer, S. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb21640c · Cited by 52
Ibrahim, S., Kothapalli, C. R., Kang, Q. K., & Ramamurthi, A. (2010) · Acta Biomaterialia · doi:10.1016/j.actbio.2010.08.006 · Cited by 52
Wu, J., He, C., He, H., Cheng, C., Zhu, J., Xiao, Z., Zhang, H., Li, X., Zheng, J., & Xiao, J. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb00757d · Cited by 52
Tailoring Properties of Biocompatible PEG-DMA Hydrogels with UV Light
Bäckström, S., Benavente, J., Berg, R. W., Stibius, K. B., Larsen, M. S., Bohr, H. G., & Hélix‐Nielsen, C. (2012) · Materials Sciences and Applications · doi:10.4236/msa.2012.36060 · Cited by 51
Mussel-inspired pH-triggered reversible foamed multi-responsive gel – the surprising effect of water
Vatankhah‐Varnoosfaderani, M., GhavamiNejad, A., Hashmi, S., & Stadler, F. J. (2013) · Chemical Communications · doi:10.1039/c3cc41332b · Cited by 51
Onuki, Y., Hoshi, M., Okabe, H., Fujikawa, M., Morishita, M., & Takayama, K. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.08.022 · Cited by 51
Guo, K., & Chu, C. C. (2007) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856207780852569 · Cited by 51
Pan, J., Liao, H., Gong, G., He, Y., Wang, Q., Qin, L., Zhang, Y., Ejima, H., Tardy, B. L., Richardson, J. J., et al. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.07.003 · Cited by 50
Drying and storage effects on poly(ethylene glycol) hydrogel mechanical properties and bioactivity
Luong, P., Browning, M. B., Bixler, R. S., & Cosgriff‐Hernandez, E. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34977 · Cited by 50
B12-Mediated, Long Wavelength Photopolymerization of Hydrogels
Rodgers, Z. L., Hughes, R. M., Doherty, L. M., Shell, J. R., Molesky, B. P., Brugh, A. M., Forbes, M. D. E., Moran, A. M., & Lawrence, D. S. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b00182 · Cited by 50
Fluorescent Nanogel of Arsenic Sulfide Nanoclusters
Wang, J., Loh, K. P., Wang, Z., Yan, Y., Zhong, Y. L., Xu, Q., & Ho, P. C. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900586 · Cited by 50
Synthesis and Characterization of Radiopaque Iodine-containing Degradable PVA Hydrogels
Mawad, D., Poole-Warren, L. A., Martens, P. J., Koole, L. H., Slots, T., & van Hooy‐Corstjens, C. S. J. (2007) · Biomacromolecules · doi:10.1021/bm700754m · Cited by 50
Sepulveda, A. F., Kumpgdee-Vollrath, M., Franco, M. K. K. D., Yokaichiya, F., & de Araújo, D. R. (2022) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2022.10.064 · Cited by 49
Thin Hydrogel Films With Nanoconfined Surface Reactivity by Photoinitiated Chemical Vapor Deposition
Montero, L., Baxamusa, S. H., Borrós, S., & Gleason, K. K. (2008) · Chemistry of Materials · doi:10.1021/cm802737m · Cited by 49
Münster, L., Vı́cha, J., Klofáč, J., Masař, M., Hurajová, A., & Kuřitka, I. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.06.035 · Cited by 49
Fabrication of 3D Tubular Hydrogel Materials through On-Site Surface Free Radical Polymerization
Ma, S., Rong, M., Peng, L., Bao, M., Xie, J., Wang, X., Huck, W. T. S., Zhou, F., & Liu, W. (2018) · Chemistry of Materials · doi:10.1021/acs.chemmater.8b02532 · Cited by 49
Chitosan hydrogel synthesis to remove arsenic and fluoride ions from groundwater
Burillo, J. C., Ballinas‐Casarrubias, L., Burillo, G., Guerrero-Lestarjette, E., Lardizábal‐Gutiérrez, D., & Hidalgo, H. S. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.126070 · Cited by 49
Zhang, G., Wang, D., Gu, Z.-Z., Hartmann, J., & Möhwald, H. (2005) · Chemistry of Materials · doi:10.1021/cm050414x · Cited by 49
Swelling and Diffusion in Polymerized Ionic Liquids-Based Hydrogels
Jastram, A., Lindner, T., Luebbert, C., Sadowski, G., & Kragl, U. (2021) · Polymers · doi:10.3390/polym13111834 · Cited by 53
Hydrogel-Based Scaffolds in Oral Tissue Engineering
Ayala-Ham, A. D. R., López-Gutiérrez, J., Bermúdez, M., Aguilar‐Medina, M., Sarmiento‐Sánchez, J. I., López‐Camarillo, C., Sánchez‐Schmitz, G., & Ramos‐Payán, R. (2021) · Frontiers in Materials · doi:10.3389/fmats.2021.708945 · Cited by 48
Robust Self-Healing Hydrogels Assisted by Cross-Linked Nanofiber Networks
Fang, Y., Wang, C., Zhang, Z., Shao, H., & Chen, S. (2013) · Scientific Reports · doi:10.1038/srep02811 · Cited by 48
Roy, S. G., & De, P. (2014) · Polymer · doi:10.1016/j.polymer.2014.08.072 · Cited by 48
Phase-Transition Thermodynamics of N-Isopropylacrylamide Hydrogels
Rice, C. V. (2006) · Biomacromolecules · doi:10.1021/bm060607t · Cited by 48
Deming, T. J. (2014) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1262 · Cited by 48
Radhakrishnan, A., Jose, G. M., & Kurup, G. M. (2015) · Progress in Biomaterials · doi:10.1007/s40204-015-0041-3 · Cited by 48
Designing Bioactive Delivery Systems for Tissue Regeneration
Davis, H. E., & Leach, J. K. (2010) · Annals of Biomedical Engineering · doi:10.1007/s10439-010-0135-y · Cited by 47
Deiber, J. A., Ottone, M. L., Piaggio, M. V., & Peirotti, M. B. (2009) · Polymer · doi:10.1016/j.polymer.2009.10.046 · Cited by 47
Schmitt, S., Silvestre, M. E., Tsotsalas, M. M., Winkler, A.-L., Shahnas, A., Grosjean, S., Laye, F., Gliemann, H., Lahann, J., Bräse, S., et al. (2015) · ACS Nano · doi:10.1021/acsnano.5b00483 · Cited by 47
Niu, C., Li, X., Wang, Y., Liu, X., Shi, J. Y., & Wang, X. (2019) · RSC Advances · doi:10.1039/c9ra09344c · Cited by 47
Deng, C., Chen, X., Sun, J., Lu, T., Wang, W., & Jing, X. (2007) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.22071 · Cited by 47
Preparation and characterization of hydrogels with potential for use as biomaterials
Thürmer, M. B., Diehl, C. E., Brum, F. J. B., & dos Santos, L. A. (2014) · Materials Research · doi:10.1590/1516-1439.223613 · Cited by 46
Nykänen, V. P. S., Nykänen, A., Puska, M. A., Silva, G. G., & Ruokolainen, J. (2011) · Soft Matter · doi:10.1039/c0sm01000f · Cited by 46
Lux, C. D. G., Lux, J., Collet, G., He, S., Chan, M., Olejniczak, J., Foucault‐Collet, A., & Almutairi, A. (2015) · Biomacromolecules · doi:10.1021/acs.biomac.5b00950 · Cited by 46
Whitehead, F. A., Paramita, V. D., Teimouri, S., Young, S. A., & Kasapis, S. (2018) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2018.10.026 · Cited by 46
Articular and Artificial Cartilage, Characteristics, Properties and Testing Approaches—A Review
Mostakhdemin, M., Nand, A. V., & Ramezani, M. (2021) · Polymers · doi:10.3390/polym13122000 · Cited by 47
Hussain, T., Ansari, M., Ranjha, N. M., Khan, I. U., & Shahzad, Y. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/340737 · Cited by 48
Influence of crosslinking on the stiffness and degradation of dermis‐derived hydrogels
Pilipchuk, S. P., Vaicik, M. K., Larson, J. C., Gazyakan, E., Cheng, M., & Brey, E. M. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34602 · Cited by 45
Pickering Stabilized Peptide Gel Particles as Tunable Microenvironments for Biocatalysis
Scott, G. G., Roy, S., Abul‐Haija, Y. M., Fleming, S., Bai, S., & Ulijn, R. V. (2013) · Langmuir · doi:10.1021/la403448s · Cited by 45
Facile formation of dynamic hydrogel microspheres for triggered growth factor delivery
King, W. J., Toepke, M. W., & Murphy, W. L. (2010) · Acta Biomaterialia · doi:10.1016/j.actbio.2010.10.026 · Cited by 45
Enzymatically cross-linked poly(γ-glutamic acid) hydrogel with enhanced tissue adhesive property
Kim, M. H., Lee, J. N., Lee, J., Lee, H., & Park, W. H. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c00411 · Cited by 45
Thermoresponsive Behavior of Poly(N-Isopropylacrylamide) Hydrogels Containing Gold Nanostructures
Pong, F. Y., Lee, M., Bell, J. R., & Flynn, N. T. (2006) · Langmuir · doi:10.1021/la0534165 · Cited by 45
Murphy, D. J., Sankalia, M. G., Loughlin, R. G., Donnelly, R. F., Jenkins, M. G., & McCarron, P. A. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.11.018 · Cited by 45
Progress and challenges of the bioartificial pancreas
Hwang, P. T. J., Shah, D. K., Garcia, J. A., Bae, C. Y., Lim, D., Huiszoon, R. C., Alexander, G. C., & Jun, H. (2016) · Nano Convergence · doi:10.1186/s40580-016-0088-4 · Cited by 44
Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds
Hsu, C., George, J. H., Waller, S., Besnard, C., Nagel, D. A., Hill, E. J., Coleman, M. D., Korsunsky, A. M., Cui, Z., & Ye, H. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.07.008 · Cited by 44
Glucose‐Responsive Charge‐Switchable Lipid Nanoparticles for Insulin Delivery
Liu, Y., Wang, Y., Yao, Y., Zhang, J., Liu, W., Ji, K., Wei, X., Wang, Y., Liu, X., Zhang, S., et al. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202303097 · Cited by 43
Self-citationLubasová, D., Niu, H., Zhao, X., & Lin, T. (2015) · RSC Advances · doi:10.1039/c5ra07514a · Cited by 43
Physics of engineered protein hydrogels
Kim, M., Tang, S., & Olsen, B. D. (2013) · Journal of Polymer Science Part B Polymer Physics · doi:10.1002/polb.23270 · Cited by 42
Modulating growth factor release from hydrogels via a protein conformational change
King, W. J., Mohammed, J. S., & Murphy, W. L. (2009) · Soft Matter · doi:10.1039/b819060g · Cited by 43
Demirdirek, B., & Uhrich, K. E. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.05.047 · Cited by 43
Combined Cononsolvency and Temperature Effects on Adsorbed PNIPAM Microgels
Backes, S., Krause, P., Tabaka, W., Witt, M. U., & von Klitzing, R. (2017) · Langmuir · doi:10.1021/acs.langmuir.7b02903 · Cited by 43
Fabrication of Hydrogel Materials for Biomedical Applications
Yang, J., Olanrele, O. S., Zhang, X., & Hsu, C. C. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0947-2_12 · Cited by 45
Why Chain Length of Hyaluronan in Eye Drops Matters
Müller‐Lierheim, W. G. K. (2020) · Diagnostics · doi:10.3390/diagnostics10080511 · Cited by 45
Improved Mechanical Properties of Zwitterionic Hydrogels with Hydroxyl Groups
He, Y., Tsao, H., & Jiang, S. (2012) · The Journal of Physical Chemistry B · doi:10.1021/jp300205m · Cited by 42
Smart hydrogel with shape memory for biomedical applications
Kabir, M. H., Hazama, T., Watanabe, Y., Gong, J., Murase, K., Sunada, T., & Furukawa, H. (2014) · Journal of the Taiwan Institute of Chemical Engineers · doi:10.1016/j.jtice.2014.09.035 · Cited by 42
Bioengineering Methods for Analysis of Cells In Vitro
Underhill, G. H., Galie, P. A., Chen, C. S., & Bhatia, S. N. (2012) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-101011-155709 · Cited by 41
Multi-scale characterization of surface-crosslinked superabsorbent polymer hydrogel spheres
Chang, S., Kim, M., Oh, S., Min, J. H., Kang, D., Han, C., Ahn, T., Koh, W., & Lee, H. (2018) · Polymer · doi:10.1016/j.polymer.2018.04.073 · Cited by 44
Rakovsky, A., Marbach, D., Lotan, N., & Lanir, Y. (2008) · Journal of Applied Polymer Science · doi:10.1002/app.29420 · Cited by 42
Anionic and cationic dextran hydrogels for post-loading and release of proteins
Schillemans, J. P., Verheyen, E., Barendregt, A., Hennink, W. E., & van Nostrum, C. F. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.11.027 · Cited by 41
Bae, M., Gemeinhart, R. A., Divan, R., Suthar, K. J., & Mancini, D. C. (2010) · Journal of Vacuum Science & Technology B Nanotechnology and Microelectronics Materials Processing Measurement and Phenomena · doi:10.1116/1.3517716 · Cited by 41
Uygun, M., Uygun, D. A., Özçalışkan, E., Akgöl, S., & Deni̇zli̇, A. (2012) · Journal of Chromatography B · doi:10.1016/j.jchromb.2012.01.014 · Cited by 41
Mechanical Behaviors of Highly Swollen Supramolecular Hydrogels Mediated by Pseudorotaxanes
Li, Z., Zhang, Y., Wang, H.-Y., Li, H., & Liu, Y. (2017) · Macromolecules · doi:10.1021/acs.macromol.6b02459 · Cited by 41
Patton, J. N., & Palmer, A. F. (2006) · Langmuir · doi:10.1021/la052883j · Cited by 41
Cho, N., Elazar, M., Xiong, A., Lee, W., Chiao, E. T., Baker, J. C., Frank, C. W., & Glenn, J. S. (2008) · Biomedical Materials · doi:10.1088/1748-6041/25/1/011001 · Cited by 40
Gels: From Soft Matter to BioMatter
Shibayama, M., Li, X., & Sakai, T. (2017) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.7b04614 · Cited by 40
Nonlinear Elasticity and Swelling of Comb and Bottlebrush Networks
Jacobs, M., Liang, H., Dashtimoghadam, E., Morgan, B. J., Sheiko, S. S., & Dobrynin, A. V. (2019) · Macromolecules · doi:10.1021/acs.macromol.9b00956 · Cited by 40
Preparation and characterization of mucinated agarose: A mucin–agarose physical crosslink
Builders, P. F., Kunle, O. O., & Adikwu, M. U. (2008) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2008.01.006 · Cited by 40
Bai, S., Wu, C., Gawlitza, K., von Klitzing, R., Ansorge‐Schumacher, M. B., & Wang, D. (2010) · Langmuir · doi:10.1021/la102042m · Cited by 40
Pourjavadi, A., & Barzegar, S. (2009) · Starch - Stärke · doi:10.1002/star.200800032 · Cited by 39
Matsumura, K., Hayami, T., Hyon, S., & Tsutsumi, S. (2009) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32448 · Cited by 39
Berdichevski, A., Shachaf, Y., Wechsler, R., & Seliktar, D. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.11.015 · Cited by 40
Enhanced adsorption capacity of cryogel bed by incorporating polymeric resin particles
Wang, C., Dong, X., Jiang, Z., & Sun, Y. P. (2012) · Journal of Chromatography A · doi:10.1016/j.chroma.2012.11.059 · Cited by 39
Famili, A., & Rajagopal, K. (2017) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.7b00067 · Cited by 42
Cooperativity in a Chemomechanical Polymer: A Chemically Induced Macroscopic Logic Gate
Schneider, H., Tianjun, L., Lomadze, N., & Palm, B. S. (2004) · Advanced Materials · doi:10.1002/adma.200306249 · Cited by 39
Thermal analysis characterization of PAAm-co-MC hydrogels
Alves, T. V. G., Tavares, E. J. M., Aouada, F. A., Negrão, C. A. B., Oliveira, M. E. C., Duarte, A. P., da Costa, C. E. F., Júnior, J. O. C. S., & Ribeiro-Costa, R. M. (2011) · Journal of Thermal Analysis and Calorimetry · doi:10.1007/s10973-011-1572-z · Cited by 39
Aziz, M. A., Cabral, J. D., Brooks, H. J. L., McConnell, M. A., Fitzpatrick, C., Hanton, L. R., & Moratti, S. C. (2014) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.33206 · Cited by 39
HaqAsif, A., Karnakar, R. R., Sreeharsha, N., Gite, V. V., Borane, N., Al-Dhubiab, B. E., Kaliyadan, F., Rasool, T., Nanjappa, S. H., & Meravanige, G. (2021) · Journal of Polymers and the Environment · doi:10.1007/s10924-020-01934-1 · Cited by 38
Qu, X., Yan, L., Liu, S., Tan, Y., Xiao, J., Cao, Y., Chen, K., Xiao, W., Li, B., & Liao, X. (2021) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2021.1932070 · Cited by 38
Engineered Synthetic Matrices for Human Intestinal Organoid Culture and Therapeutic Delivery
Mulero‐Russe, A., & García, A. J. (2023) · Advanced Materials · doi:10.1002/adma.202307678 · Cited by 42
Structure-Property Relationships in Hydrogels
Borzacchiello, A., & Ambrosio, L. (2009) · Springer eBooks · doi:10.1007/978-88-470-1104-5_2 · Cited by 38
Critical factors affecting cell encapsulation in superporous hydrogels
Desai, E., Tang, M. Y., Ross, A. E., & Gemeinhart, R. A. (2012) · Biomedical Materials · doi:10.1088/1748-6041/7/2/024108 · Cited by 38
Wenceslau, A. C., dos Santos, F. G., Ramos, É. R. F., Nakamura, C. V., Rubira, A. F., & Muniz, E. C. (2012) · Materials Science and Engineering C · doi:10.1016/j.msec.2012.04.001 · Cited by 38
New l-valine-based hydrogelators: formation of supramolecular hydrogels
Suzuki, M., Owa, S., Yumoto, M., Kimura, M., Shirai, H., & Hanabusa, K. (2004) · Tetrahedron Letters · doi:10.1016/j.tetlet.2004.05.056 · Cited by 38
Smith, T. J., Kennedy, J. E., & Higginbotham, C. L. (2008) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2008.10.003 · Cited by 38
Bhat, V. T., James, N. R., & Jayakrishnan, A. (2007) · Polymer International · doi:10.1002/pi.2332 · Cited by 38
Siegrist, J., Kazarian, T., Ensor, M., Joel, S., Madou, M. J., Wang, P., & Daunert, S. (2010) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2010.06.031 · Cited by 37
Molecular Recognition in a Supramolecular Polymer System Translated into Mechanical Motion
Schneider, H., Tianjun, L., & Lomadze, N. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200219965 · Cited by 37
Transport of biological molecules in surfactant–alginate composite hydrogels
Stoppel, W. L., White, J. C., Horava, S. D., Bhatia, S. R., & Roberts, S. C. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.07.009 · Cited by 37
Confocal Microscopy and Albumin Penetration into Contact Lenses
Luensmann, D., Glasier, M.-A., Zhang, F., Bantseev, V., SIMPSON, T. L., & Jones, L. (2007) · Optometry and Vision Science · doi:10.1097/opx.0b013e3181559ea4 · Cited by 36
Wang, R., Li, Q. F., Chi, B., Wang, X., Xu, Z., Xu, Z., Chen, S., & Xu, H. L. (2017) · Chemical Communications · doi:10.1039/c6cc09326d · Cited by 36
Zehtabi, F., Ispas‐Szabo, P., Djerir, D., Sivakumaran, L., Annabi, B., Soulez, G., Mateescu, M. A., & Lerouge, S. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.09.021 · Cited by 36
Banerjee, S. L., Swift, T., Hoskins, R., Rimmer, S., & Singha, N. K. (2019) · Journal of Materials Chemistry B · doi:10.1039/c8tb02852d · Cited by 36
Fabrication of micropatterns of nanoarrays on a polymeric gel surface
Liu, P., Sun, J., Huang, J., Peng, R., Tang, J., & Ding, J. (2009) · Nanoscale · doi:10.1039/b9nr00124g · Cited by 36
Synthesis and properties of coumarin-derived organogelators
Yu, H., Mizufune, H., Uenaka, K., Moritoki, T., & Koshima, H. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.07.003 · Cited by 36
Metadata
- Authors
- Peppas, N. A., Huang, Y., Torres-Lugo, M., Ward, J. H., & Zhang, J.
- Affiliations
- Purdue University West Lafayette (US)
- Program on Therapeutic and Diagnostic Devices, Biomaterials and Drug Delivery Laboratories, School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907-1283;
- Venue
- Annual Review of Biomedical Engineering
- Publisher
- Annual Reviews
- Published
- 2000-08
- Volume
- 2
- Issue
- 1
- Pages
- 9-29
- ISSN
- 1523-9829 (ISSN-L)
- 1545-4274
- OpenAlex
- W2157220384
- Cited by
- 1,016
- References
- 81
- Citations by year
- 2026: 17 · 2025: 24 · 2024: 23 · 2023: 26 · 2022: 28 · 2021: 41 · 2020: 42 · 2019: 36 · 2018: 61 · 2017: 53 · 2016: 57 · 2015: 56 · 2014: 56 · 2013: 65 · 2012: 65
- FWCI
- 1.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Keywords
- hydrogels, biohydrogel, chain conformation, pH-responsive hydrogels, thermosensitive hydrogel, stimuli-responsive hydrogels
- MeSH terms
- Biomedical Engineering, Chemistry, Physical, Diffusion, Surface Properties, Molecular Structure, Hydrogels, Chemical Phenomena
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review