The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration
Open accessAbstract
Directed cell migration is a physical process that requires dramatic changes in cell shape and adhesion to the extracellular matrix. For efficient movement, these processes must be spatiotemporally coordinated. To a large degree, the morphological changes and physical forces that occur during migration are generated by a dynamic filamentous actin (F-actin) cytoskeleton. Adhesion is regulated by dynamic assemblies of structural and signaling proteins that couple the F-actin cytoskeleton to the extracellular matrix. Here, we review current knowledge of the dynamic organization of the F-actin cytoskeleton in cell migration and the regulation of focal adhesion assembly and disassembly with an emphasis on how mechanical and biochemical signaling between these two systems regulate the coordination of physical processes in cell migration.
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Cites
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“At the level of protein structure, directional forces on FA proteins are thought to drive localized unfolding or conformational changes that unmask protein binding sites (Vogel & Sheetz 2006).”
BackgroundEffects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
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Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex
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Cited by
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
Halder, G., Dupont, S., & Piccolo, S. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3416 · Cited by 985
Mechanoreciprocity in cell migration
van Helvert, S., Storm, C., & Friedl, P. (2018) · Nature Cell Biology · doi:10.1038/s41556-017-0012-0 · Cited by 587
Actin–microtubule crosstalk in cell biology
Dogterom, M., & Koenderink, G. H. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0067-1 · Cited by 574
Cell-ECM traction force modulates endogenous tension at cell–cell contacts
Maruthamuthu, V., Sabass, B., Schwarz, U. S., & Gardel, M. L. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011123108 · Cited by 520
Self-citationRole of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction
Dupont, S. (2016) · Experimental Cell Research · doi:10.1016/j.yexcr.2015.10.034 · Cited by 449
Metadata
- Authors
- Gardel, M. L., Schneider, I. C., Aratyn-Schaus, & Waterman, C. M.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2010-11-10
- Volume
- 26
- Issue
- 1
- Pages
- 315-333
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2148454908
- Cited by
- 981
- References
- 9
- FWCI
- 2.80
- Type
- journal article
- Language
- en
- Open access
- green
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- Gardel, M. L., Schneider, I. C., Aratyn-Schaus, & Waterman, C. M. (2010). Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.011209.122036
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
