Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

Matrix elasticity directs stem cell lineage specification

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Role of YAP/TAZ in mechanotransduction

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Geometric Control of Cell Life and Death

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Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

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Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

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Tensional homeostasis and the malignant phenotype

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Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

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TEAD mediates YAP-dependent gene induction and growth control

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Role of cell shape in growth control

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Local force and geometry sensing regulate cell functions

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The Hippo Signaling Pathway in Development and Cancer

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A ROCK inhibitor permits survival of dissociated human embryonic stem cells

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Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

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Cell adhesion: integrating cytoskeletal dynamics and cellular tension

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The Biology of YAP/TAZ: Hippo Signaling and Beyond

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Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

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A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

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Mechanotransduction gone awry

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The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

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Actin dynamics control SRF activity by regulation of its coactivator MAL

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Mechanotransduction in vascular physiology and atherogenesis

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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

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Piezo1 integration of vascular architecture with physiological force

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Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer

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Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

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Hippo signaling: growth control and beyond

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TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation

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Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis

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Balancing forces: architectural control of mechanotransduction

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Transduction of mechanical and cytoskeletal cues by YAP and TAZ

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Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

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α-Catenin as a tension transducer that induces adherens junction development

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Cell–matrix adhesion

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Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

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Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

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Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

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Hippo pathway regulation by cell morphology and stress fibers

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Sensing the environment: a historical perspective on integrin signal transduction

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Mechanotransduction in development: a growing role for contractility

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Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

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Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikisPreprint

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Metabolic control of YAP and TAZ by the mevalonate pathway

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Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL

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Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

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TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

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Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

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Mechanically Activated Ion Channels

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The integrin adhesome: from genes and proteins to human disease

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Use the force: membrane tension as an organizer of cell shape and motility

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The Hippo Pathway Regulates Wnt/β-Catenin Signaling

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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

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Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

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Fibrotic extracellular matrix activates a profibrotic positive feedback loop

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E-cadherin junctions as active mechanical integrators in tissue dynamics

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Mechanical strain induces E-cadherin–dependent Yap1 and β-catenin activation to drive cell cycle entry

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A mechanosensitive transcriptional mechanism that controls angiogenesis

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The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase

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Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor ProgressionPreprint

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Role of TAZ as mediator of Wnt signaling.

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Fibronectin controls capillary endothelial cell growth by modulating cell shape.

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Engineering gene expression and protein synthesis by modulation of nuclear shape

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Vascular remodeling of the mouse yolk sac requires hemodynamic force

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Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.

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Hematopoietic Stem Cell Development Is Dependent on Blood Flow

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Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

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Collective and single cell behavior in epithelial contact inhibition

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Modulating F‐actin organization induces organ growth by affecting the Hippo pathway

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Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of <i>Yap65</i>

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The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases.

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Forcing Stem Cells to Behave: A Biophysical Perspective of the Cellular Microenvironment

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Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

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Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

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Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

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YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

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Aerobic glycolysis tunes YAP/TAZ transcriptional activity

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LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

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Cell shape controls terminal differentiation of human epidermal keratinocytes.

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The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

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Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization

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Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis

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Cell-Extracellular Matrix Interactions in Normal and Diseased Skin

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