Hyaluronan in Tissue Injury and Repair

A Toll-like receptor recognizes bacterial DNA

Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature · doi:10.1038/35047123 · Cited by 6,491

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., & Akira, S. (1999) · Immunity · doi:10.1016/s1074-7613(00)80119-3 · Cited by 3,680

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Hayashi, F., Smith, K. D., Ozinsky, A., Hawn, T. R., Yi, E. C., Goodlett, D. R., Eng, J. K., Akira, S., Underhill, D. M., & Aderem, A. A. (2001) · Nature · doi:10.1038/35074106 · Cited by 3,605

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., & Reis e Sousa, C. (2004) · Science · doi:10.1126/science.1093616 · Cited by 3,444

CD44 is the principal cell surface receptor for hyaluronate

Aruffo, A. A., Stamenkovic, I., Melnick, M., Underhill, C. B., & Seed, B. (1990) · Cell · doi:10.1016/0092-8674(90)90694-a · Cited by 2,439

Hyaluronan: its nature, distribution, functions and turnover.

Fraser, J. R. E., Laurent, T. C., & Laurent, U. B. G. (1997) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1997.00170.x · Cited by 2,031

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

Medzhitov, R., Preston-Hurlburt, P., Kopp, E., Stadlen, A., Chen, C.-Q., Ghosh, S., & Janeway, C. (1998) · Molecules and Cells · doi:10.1016/s1097-2765(00)80136-7 · Cited by 1,783

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

Ohashi, K., Burkart, V., Flohé, S. B., & Kolb, H. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.2.558 · Cited by 1,607

LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan

Banerji, S., Ni, J., Wang, S.-X., Clasper, S., Su, J. Y., Tammi, R., Jones, M., & Jackson, D. G. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.4.789 · Cited by 1,586

Postoperative effects of intra-alveolar application of 0.2% chlorhexidine or 1% hyaluronic acid bioadhesive gels after mandibular third molar extraction: a double-blind randomized controlled clinical trial

Muñoz-Cámara, D., Zamora, G. P., & Camacho‐Alonso, F. (2020) · Clinical Oral Investigations · doi:10.1007/s00784-020-03522-y · Cited by 19

Protein kinase a mediated anti‐inflammatory effects exerted by adenosine treatment in mouse chondrocytes stimulated with IL‐1β

Campo, G. M., Avenoso, A., D’Ascola, A., Prestipino, V., Scuruchi, M., Nastasi, G., Calatroni, A., & Campo, S. (2012) · BioFactors · doi:10.1002/biof.1040 · Cited by 19

Expression profiling in exercised mdx suggests a role for extracellular proteins in the dystrophic muscle immune response

Coles, C. A., Gordon, L., Hunt, L. C., Webster, T., Piers, A. T., Kintakas, C., Woodman, K. G., Touslon, S. L., Smythe, G. M., White, J. D., et al. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz266 · Cited by 20

Microencapsulated Chitosan-Based Nanocapsules: A New Platform for Pulmonary Gene Delivery

Fernández-Paz, E., Feijoo-Siota, L., Gaspar, M. M., Csaba, N., & Remuñán‐López, C. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13091377 · Cited by 18

3’UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension

Tseng, V., Collum, S. D., Allawzi, A. M., Crotty, K. M., Yeligar, S. M., Trammell, A. W., Smith, M. R., Kang, B., Sutliff, R. L., Ingram, J. L., et al. (2022) · Matrix Biology · doi:10.1016/j.matbio.2022.06.001 · Cited by 18

Metabolite‐derived damage‐associated molecular patterns in immunological diseases

Kang, N., Ji, Z., Li, Y., Gao, J., Wu, X., Zhang, X., Duan, Q., Zhu, C., Xu, Y., Wen, L., et al. (2023) · FEBS Journal · doi:10.1111/febs.16902 · Cited by 20

Hyaluronan Binding Identifies a Functionally Distinct Alveolar Macrophage–like Population in Bone Marrow–Derived Dendritic Cell Cultures

Poon, G. F. T., Dong, Y., Marshall, K. C., Arif, A., Deeg, C., Dosanjh, M., & Johnson, P. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402506 · Cited by 18

A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates

Gold, H., Munneke, S., Dinkelaar, J., Overkleeft, H. S., Aerts, J. M. F. G., Codée, J. D. C., & van der MAREL, G. A. (2011) · Carbohydrate Research · doi:10.1016/j.carres.2011.03.042 · Cited by 18

Reducing the Foreign Body Reaction by Surface Modification with Collagen/Hyaluronic Acid Multilayered Films

Hsieh, C. Y. C., Hu, F.-W., Chen, W., & Tsai, W. (2014) · ISRN Biomaterials · doi:10.1155/2014/718432 · Cited by 19

Hyaluronic Acid Induces COX-2 Expression via CD44 in Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy

Lim, H. S., Back, K. O., Kim, H. J., Choi, Y., Park, Y., & Kook, K. H. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-14873 · Cited by 18

Gelation time, homogeneity, and rupture testing of alginate‐calcium carbonate‐hydrogen peroxide gels for use as wound dressings

Alexander, B. R., Murphy, K. E., Gallagher, J., Farrell, G. F., & Taggart, G. (2011) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31965 · Cited by 18

Extracellular Vesicles from Caveolin-Enriched Microdomains Regulate Hyaluronan-Mediated Sustained Vascular Integrity

Mirzapoiazova, T., Lennon, F. E., Mambetsariev, B., Allen, M., Riehm, J., Poroyko, V. A., & Singleton, P. A. (2015) · International Journal of Cell Biology · doi:10.1155/2015/481493 · Cited by 18

Maintenance of stem cell viability and differentiation potential following cryopreservation within 3-dimensional hyaluronic acid hydrogels

Khetan, S., & Corey, O. (2019) · Cryobiology · doi:10.1016/j.cryobiol.2019.08.001 · Cited by 18

Toll-Like Receptors 2 and 4 Polymorphisms in Age-Related Macular Degeneration

Güven, M., Batar, B., Mutlu, T., Bostancı, M., Mete, M., Aras, C., & Ünal, M. (2015) · Current Eye Research · doi:10.3109/02713683.2015.1067326 · Cited by 19

Alteration in immune responses toward N-deacetylation of hyaluronic acid

Zhang, W., Mu, H., Dong, D., Wang, D., Zhang, A., & Duan, J. (2014) · Glycobiology · doi:10.1093/glycob/cwu079 · Cited by 18

Toll like receptor 2 mediates bleomycin-induced acute lung injury, inflammation and fibrosis in mice.

刘含智, 杨红振, 米粟, 崔冰, 花芳, & Hu, Z. (2010) · PubMed · Cited by 18

Hyaluronan coated cerium oxide nanoparticles modulate CD44 and reactive oxygen species expression in human fibroblasts

Lord, M. S., Farrugia, B. L., Yan, C. M. Y., Vassie, J. A., & Whitelock, J. M. (2016) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35704 · Cited by 18

Hyaluronan supplementation as a mechanical regulator of cartilage tissue development under joint-kinematic-mimicking loading

Wu, Y., Stoddart, M. J., Wuertz‐Kozak, K., Grad, S., Alini, M., & Ferguson, S. J. (2017) · Journal of The Royal Society Interface · doi:10.1098/rsif.2017.0255 · Cited by 18

Molecular insights into the effects of sodium hyaluronate preparations in keratinocytes

Colella, G., Vicidomini, A., Soro, V., Lanza, A., & Cirillo, N. (2012) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.2011.04279.x · Cited by 18

Inflammatory reactions and drug response: importance of cytochrome P450 and membrane transporters

Dumais, G., Iovu, M. O., & du Souich, P. (2008) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.1.5.627 · Cited by 18

Recent Use of Hyaluronic Acid in Dental Medicine

Malcangi, G., Inchingolo, A. D., Trilli, I., Ferrante, L., Casamassima, L., Nardelli, P., Inchingolo, F., Palermo, A., Severino, M., Inchingolo, A. M., et al. (2025) · Materials · doi:10.3390/ma18081863 · Cited by 17

Cx43-Dependent Skeletal Phenotypes Are Mediated by Interactions between the Hapln1a-ECM and Sema3d during Fin Regeneration

Govindan, J., Tun, K. M., & Iovine, M. K. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148202 · Cited by 17

Polysaccharides for protein and peptide conjugation

Ferguson, E. L., Varache, M., Stokniene, J., & Thomas, D. W. (2019) · Elsevier eBooks · doi:10.1016/b978-0-444-64081-9.00019-x · Cited by 17

The Pro-fibrotic Response of Mesenchymal Leader Cells to Lens Wounding Involves Hyaluronic Acid, Its Receptor RHAMM, and Vimentin

Menko, A. S., Romisher, A., & Walker, J. L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.862423 · Cited by 17

Micro/nanostructured inhalable formulation based on polysaccharides: Effect of a thermoprotectant on powder properties and protein integrity

Al‐Qadi, S., Taboada, P., & Remuñán‐López, C. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.08.049 · Cited by 17

Cancer-on-a-chip for Drug Screening

Lee, I. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666190206235233 · Cited by 17

Imaging of Homeostatic, Neoplastic, and Injured Tissues by HA-Based Probes

Veiseh, M., Breadner, D. A., Ma, J., Akentieva, N., Savani, R. C., Harrison, R. E., Mikilus, D., Collis, L., Gustafson, S., Lee, T.-Y., et al. (2011) · Biomacromolecules · doi:10.1021/bm201143c · Cited by 16

Hyaluronan deposition and co-localization with inflammatory cells and collagen in a murine model of fungal allergic asthma

Ghosh, S., Samarasinghe, A. E., Hoselton, S. A., Dorsam, G. P., & Schuh, J. M. (2014) · Inflammation Research · doi:10.1007/s00011-014-0719-3 · Cited by 16

Quantification of hyaluronan (HA) using a simplified fluorophore-assisted carbohydrate electrophoresis (FACE) procedure ☆

Midura, R. J., Cali, V., Lauer, M. E., Calabro, A. R., & Hascall, V. (2017) · Methods in cell biology · doi:10.1016/bs.mcb.2017.08.017 · Cited by 16

High molecular weight hyaluronic acid: a two‐pronged protectant against infection of the urogenital tract?

Mowbray, C., Shams, S., Chung, G., Stanton, A., Aldridge, P. D., Suchenko, A., Pickard, R. S., Ali, A., & Hall, J. (2018) · Clinical & Translational Immunology · doi:10.1002/cti2.1021 · Cited by 17

Importance of biomaterials in biomedical engineering

Yousaf, S. S., Houacine, C., Khan, I., Ahmed, W., & Jackson, M. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819712-7.00011-5 · Cited by 16

Biocompatibility of Materials for Biomedical Engineering

Tyan, Y., Yang, M., Chang, C.-C., & Chung, T. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-3262-7_9 · Cited by 16

Absorption, distribution, metabolism and excretion of hyaluronic acid during pregnancy: a matter of molecular weight

Unfer, V., Tilotta, M., Kaya, C., Noventa, M., Török, P., Alkatout, İ., Gitas, G., Bilotta, G., & Laganà, A. S. (2021) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2021.1931682 · Cited by 16

The role of hyaluronan synthesis and degradation in the critical respiratory illness COVID-19

Albtoush, N., & Petrey, A. C. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00071.2022 · Cited by 16

Hyaluronan oligosaccharides perturb lymphocyte slow rolling on brain vascular endothelial cells: Implications for inflammatory demyelinating disease

Winkler, C. W., Foster, S. C., Itakura, A., Matsumoto, S. G., Asari, A., McCarty, O. J. T., & Sherman, L. S. (2013) · Matrix Biology · doi:10.1016/j.matbio.2013.01.002 · Cited by 16

Hyaluronidase-Loaded PLGA Microparticles as a New Strategy for the Treatment of Pulmonary Fibrosis

Bitencourt, C. D. S., Gelfuso, G. M., Pereira, P. A. T., de Assis, P. A., Tefé‐Silva, C., Ramos, S. G., Arantes, E. C., & Faccioli, L. H. (2014) · Tissue Engineering Part A · doi:10.1089/ten.tea.2013.0403 · Cited by 16

Pharmacokinetics and Pharmacodynamics of Hyaluronan Infused into Healthy Human Volunteers

Hamilton, S. R., Veiseh, M., Tölg, C., Tirona, R. G., Richardson, J., Brown, R., Ángel-González, M., Vanzieleghem, M. A., Anderson, P. S., Asculai, S. S., et al. (2009) · The Open Drug Metabolism Journal · doi:10.2174/1874073100903010043 · Cited by 16

Deciphering Drug Resistance: Investigating the Emerging Role of Hyaluronan Metabolism and Signaling and Tumor Extracellular Matrix in Cancer Chemotherapy

Vitale, D. L., Parnigoni, A., Viola, M., Karousou, E. G., Sevic, I., Moretto, P., Passi, A. G., Alaniz, L. D., & Vigetti, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147607 · Cited by 15

Biomaterials for on-chip organ systems

Hassan, S., Heinrich, M. A., Çeçen, B., Prakash, J., & Zhang, Y. S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102906-0.00019-2 · Cited by 18

A dZnONPs Enhanced Hybrid Injectable Photocrosslinked Hydrogel for Infected Wounds Treatment

Chen, Y., Xiang, Y., Zhu, T., Chen, S., Du, J., Luo, J., & Yan, X. (2022) · Gels · doi:10.3390/gels8080463 · Cited by 15

Increased hyaluronan levels and decreased dendritic cell activation are associated with tumor invasion in murine lymphoma cell lines

Russo, R. I. C., Ernst, G., Lompardía, S. L., Blanco, G. A. C., Álvarez, É., García, M. G., & Hajos, S. E. (2011) · Immunobiology · doi:10.1016/j.imbio.2011.12.006 · Cited by 15

A link between smooth muscle cell death and extracellular matrix degradation during vascular atrophy

Kenagy, R. D., Min, S.-K., Mulvihill, E. R., & Clowes, A. W. (2011) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2010.12.070 · Cited by 15

Oral Administration of Hyaluronan Reduces Bone Turnover in Ovariectomized Rats

Ma, J., Granton, P. V., Holdsworth, D. W., & Turley, E. A. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf300651d · Cited by 15

Differential effects of hyaluronan synthase 3 deficiency after acute vs chronic liver injury in mice

McCracken, J. M., Jiang, L., Deshpande, K., O’Neil, M. F., & Pritchard, M. T. (2016) · Fibrogenesis & Tissue Repair · doi:10.1186/s13069-016-0041-5 · Cited by 15

Hang on tight: reprogramming the cell with microstructural cues

Le, L. V., Mkrtschjan, M. A., Russell, B., & Desai, T. A. (2019) · Biomedical Microdevices · doi:10.1007/s10544-019-0394-9 · Cited by 15

Targeting the Stromal Pro-Tumoral Hyaluronan-CD44 Pathway in Pancreatic Cancer

Koltai, T., Reshkin, S. J., Carvalho, T. M. A., & Cardone, R. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083953 · Cited by 15

Exosomes from MicroRNA-125b-Modified Adipose-Derived Stem Cells Promote Wound Healing of Diabetic Foot Ulcers

Guo, E., Wang, L., Wu, J., & Chen, Q. (2024) · Current Stem Cell Research & Therapy · doi:10.2174/011574888x287173240415050555 · Cited by 14

Phototuning of Hyaluronic‐Acid‐Based Hydrogel Properties to Control Network Formation in Human Vascular Endothelial Cells

Elvitigala, K. C. M. L., Mohan, L., Mubarok, W., & Sakai, S. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303787 · Cited by 14

Role of the endothelial cell glycocalyx in sepsis-induced acute kidney injury

Wang, Y., Zhang, Z., Qu, X., & Zhou, G. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1535673 · Cited by 14

Relationship of Circulating Hyaluronic Acid Levels to Disease Control in Asthma and Asthmatic Pregnancy

Eszes, N., Toldi, G., Bohács, A., Ivancsó, I., Müller, V., Rigó, J., Losonczy, G., Vásárhelyi, B., & Tamási, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094678 · Cited by 14

Cytokine Binding by Polysaccharide−Antibody Conjugates

Sun, L. T., Buchholz, K. S., Lotze, M. T., & Washburn, N. R. (2010) · Molecular Pharmaceutics · doi:10.1021/mp100150z · Cited by 14

High-Performance Agent-Based Modeling Applied to Vocal Fold Inflammation and Repair

Seekhao, N., Shung, C., JáJá, J. F., Mongeau, L., & Li‐Jessen, N. Y. K. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00304 · Cited by 14

Improved physical and osteoinductive properties of demineralized bone matrix by gelatin methacryloyl formulation

Ramis, J. M., Blasco‐Ferrer, M., Calvo, J., Villa, O., Cladera, M. M., Corbillo, C., Gayà, A., & Monjo, M. (2020) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.3012 · Cited by 14

Hyaluronan induces migration of multidrug-resistant lymphoma cell lines in vitro through Tiam1 activation by a PI3K-dependent mechanism

Russo, R. I. C., Alaniz, L. D., Saccodossi, N., Lompardía, S. L., Blanco, G. A. C., Álvarez, É., García, M. G., & Hajos, S. E. (2010) · Leukemia Research · doi:10.1016/j.leukres.2010.02.020 · Cited by 14

Fabrication, characterization, and biological assessment of multilayer DNA coatings on sandblasted‐dual acid etched titanium surface

Liu, L., Song, L., Yang, G., Zhao, S., & He, F. (2011) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.33059 · Cited by 14

The Role of Nonocclusive Sources of Acute Gut Injury in Cardiac Surgery

Karhausen, J., & Stafford‐Smith, M. (2013) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2013.04.016 · Cited by 14

Biomaterial applications in neural therapy and repair

Ghuman, H., & Modo, M. (2016) · Chinese Neurosurgical Journal · doi:10.1186/s41016-016-0057-0 · Cited by 14

A Hyaluronan-binding Peptide (P15-1) Reduces Inflammatory and Catabolic Events in IL-1β-treated Human Articular Chondrocytes

Shortt, C., Luyt, L. G., Turley, E. A., Cowman, M. K., & Kirsch, T. (2020) · Scientific Reports · doi:10.1038/s41598-020-57586-7 · Cited by 14

Immune effects of mesenchymal stem cells: Implications for Charcot–Marie–Tooth disease

Leal, A., Ichim, T. E., Marleau, A. M., Lara, F., Kaushal, S., & Riordan, N. H. (2008) · Cellular Immunology · doi:10.1016/j.cellimm.2008.06.003 · Cited by 14

Advancements in dual-targeting nanoparticle strategies for enhanced atherosclerosis therapy: Overcoming limitations of single-targeting approaches

Yang, C., Mo, L., Zhang, G., Dai, Y., Li, B., Tan, Z., Guo, Y., Lu, S., Hong, Y., He, H., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.09.023 · Cited by 13

Curcumin-loaded γ -cyclodextrin-grafted hyaluronic acid nanoassimblies: In vitro investigation of anti-proliferative, wound healing, and anti-inflammatory potential

Adaileh, F., Alshaer, W., Nsairat, H., Alqudah, D. A., Wehaibi, S., Daoud, F., Albuqain, R., Alsotari, S. T., Bawab, A. A., & Odeh, F. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104886 · Cited by 14

Middle Ear Packing

Lipan, M. J., Alava, I., Abi-Hachem, R. N., Vernon, S. E., Water, T. R. V. D., & Angeli, S. I. (2011) · Otolaryngology · doi:10.1177/0194599810395115 · Cited by 13

Dental pulp stem cells express proteins involved in the local invasiveness of odontogenic myxoma

Miyagi, S. P. H., Maranduba, C. M. D. C., Silva, F. D. S., & Marques, M. M. (2012) · Brazilian Oral Research · doi:10.1590/s1806-83242012000200009 · Cited by 13

Cyclooxygenase inhibitors repress vascular hyaluronan‐synthesis in murine atherosclerosis and neointimal thickening

Marzoll, A., Nagy, N., Wördehoff, L., Dai, G., Fries, S., Lindner, V., Großer, T., & Fischer, J. W. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00736.x · Cited by 13

Analysis of Hyaluronan Synthase Activity

Vigetti, D., Karousou, E. G., Viola, M., & Passi, A. G. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1714-3_18 · Cited by 13

Update in Diffuse Parenchymal Lung Disease 2008

Behr, J., & Thannickal, V. J. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200901-0011up · Cited by 13

Initial Experience Using a Hyaluronate-Iodine Complex for Wound Healing

Brenes, R. A., Ajemian, M. S., Macaron, S. H., Panait, L., & Dudrick, S. J. (2011) · The American Surgeon · doi:10.1177/000313481107700329 · Cited by 13

The Amazing Power of Cancer Cells to Recapitulate Extraembryonic Functions: The Cuckoo's Tricks

Arias, J. I., Aller, M., Prieto, I., Arias, A., de Julian, Z., Yang, H., & Árias, J. (2011) · Journal of Oncology · doi:10.1155/2012/521284 · Cited by 13

Polymer-conjugated inhibitors of tumor necrosis factor-α for local control of inflammation

Washburn, N. R., Prata, J. E., Friedrich, E. E., Ramadan, M. H., Elder, A. N., & Sun, L. T. (2013) · Biomatter · doi:10.4161/biom.25597 · Cited by 13

Hyaluronan: Structure, Metabolism, and Biological Properties

Passi, A. G., & Vigetti, D. (2019) · Biologically-inspired systems · doi:10.1007/978-3-030-12919-4_4 · Cited by 14

Low molecular weight hyaluronan inhibits lung epithelial ion channels by activating the calcium-sensing receptor

Lazrak, A., Song, W., Yu, Z., Zhang, S., Nellore, A., Hoopes, C. W., Woodworth, B. A., & Matalon, S. (2023) · Matrix Biology · doi:10.1016/j.matbio.2023.02.002 · Cited by 12

The significant role of glycosaminoglycans in tooth development

Inubushi, T., Nag, P., Sasaki, J., Shiraishi, Y., & Yamashiro, T. (2024) · Glycobiology · doi:10.1093/glycob/cwae024 · Cited by 12

Characterization of Biocompatible Scaffolds Based on Gelatin and Hyaluronic Acid for Fibroblasts Culture

Zhou, Z., Yang, Z., Huang, T., Liu, L., Liu, Q., Zeng, W., Cao, D., & Ma, S. (2012) · Polymers and Polymer Composites · doi:10.1177/096739111202000904 · Cited by 12

Hydrogel-Supported, Engineered Model of Vocal Fold Epithelium

Ravikrishnan, A., Fowler, E. W., Stuffer, A. J., & Jia, X. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c01741 · Cited by 12

Preliminary study of efficacy of hyaluronic acid on caustic esophageal burns in an experimental rat model

Çevik, M., Demi̇r, T., Karadağ, Ç. A., Ketani, M. A., Çelık, H., Kaplan, D. S., & Böleken, M. E. (2013) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2012.08.015 · Cited by 12

Plant-Derived Lactobacillus paracasei IJH-SONE68 Improves Chronic Allergy Status: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Noda, M., Kanno, K., Danshiitsoodol, N., Higashikawa, F., & Sugiyama, M. (2021) · Nutrients · doi:10.3390/nu13114022 · Cited by 12

Gene expression profile of a newly established choriocarcinoma cell line, iC3-1, compared to existing choriocarcinoma cell lines and normal placenta

Kobayashi, Y., Banno, K., Shimizu, T., Ueki, A., Tsuji, K., Masuda, K., Kisu, I., Nomura, H., Tominaga, E., Nagano, O., et al. (2012) · Placenta · doi:10.1016/j.placenta.2012.11.003 · Cited by 12

Clearance Kinetics of Biomaterials Affects Stem Cell Retention and Therapeutic Efficacy

Lai, C. Y., Wu, P. J., Roffler, S. R., Lee, S. T., Hwang, S.-M., Wang, S., Wang, K., & Hsieh, P. C. H. (2013) · Biomacromolecules · doi:10.1021/bm401583b · Cited by 12

Inflammation, Wound Healing, and Fibrosis

Ghatak, S., Hascall, V., Moreno‐Rodriguez, R. A., Markwald, R. R., & Misra, S. (2017) · Wiley eBooks · doi:10.1002/9781119282518.ch15 · Cited by 12

NFAT signaling in human mesenchymal stromal cells affects extracellular matrix remodeling and antifungal immune responses

Tidu, F., Zuani, M. D., Jose, S. S., Bendíčková, K., Kubala, L., Caruso, F., Cavalieri, F., Forte, G., & Frič, J. (2021) · iScience · doi:10.1016/j.isci.2021.102683 · Cited by 11

Preparation of novel hybrid gels from polyaspartamides and natural alginate or hyaluronate by click reaction

Bui, Q. T., Jeon, Y. S., Um, S. H., Chung, D. J., & Kim, J. (2015) · Journal of Polymer Research · doi:10.1007/s10965-014-0649-3 · Cited by 11

Balance Between Tooth Size and Tooth Number Is Controlled by Hyaluronan

Sánchez, N., González-Ramírez, M. C., Contreras, E. G., Ubilla, A., Li, J., Valencia, A., Wilson, A., Green, J. B. A., Tucker, A. S., & Gaete, M. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00996 · Cited by 11

Substrate-induced phenotypic switches of human smooth muscle cells: an in vitro study of in-stent restenosis activation pathways

Guildford, A. L., Helen, S., Morris, C., & Santin, M. (2010) · Journal of The Royal Society Interface · doi:10.1098/rsif.2010.0532 · Cited by 11

Endothelial glycocalyx of blood circulation system. I. Detection, components, and structural organization

Maksimenko, A. V., & Turashev, A. D. (2014) · Russian Journal of Bioorganic Chemistry · doi:10.1134/s1068162014020113 · Cited by 11

Catabolism of hyaluronan: Involvement of transition metals

Šoltés, L., & Kogan, G. (2009) · Interdisciplinary Toxicology · doi:10.2478/v10102-009-0026-y · Cited by 11

High Molecular Weight Hyaluronan Promotes Corneal Nerve Growth in Severe Dry Eyes

van Setten, G. B., Stachs, O., Dupas, B., Turhan, S. A., Seitz, B., Reitsamer, H. A., Winter, K., Horwath‐Winter, J., Guthoff, R. F., & Müller‐Lierheim, W. G. K. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9123799 · Cited by 11

Poloxamer-based hydrogel with EGCG and rhEGF for diabetic foot ulcer treatment

Mo, A., Li, L., & Yu, M. (2025) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-025-06917-z · Cited by 10

Various Coated Barrier Membranes for Better Guided Bone Regeneration: A Review

Kim, J.-Y., & Park, J. (2022) · Coatings · doi:10.3390/coatings12081059 · Cited by 10

Surface‐modified silicone T ‐tubes for prevention of tracheal stenosis in a rabbit model

Choi, J., Lim, J., Park, I. S., Seo, S. Y., Joung, Y. K., Han, D. K., & Kim, Y. (2014) · The Laryngoscope · doi:10.1002/lary.25044 · Cited by 10

MERS versus Standard Surgical Approaches for Porcine Vocal Fold Scarring with Adipose Stem Cell Constructs

Woo, J. H., King, S. N., Hoffman, H. T., Dailey, S. H., Wang, S., Christensen, M. B., & Thibeault, S. L. (2016) · Otolaryngology · doi:10.1177/0194599816645772 · Cited by 10

Topical hyaluronan alone promotes corneal epithelial cell migration whereas combination with benzalkonium chloride impairs epithelial wound healing

Seino, S., Matsuoka, R., Masuda, Y., Kunou, M., Okada, Y., & Saika, S. (2019) · Cutaneous and Ocular Toxicology · doi:10.1080/15569527.2019.1673402 · Cited by 10

Hyaluronan stimulates ex vivo B lymphocyte chemotaxis and cytokine production in a murine model of fungal allergic asthma

Ghosh, S., Hoselton, S. A., Wanjara, S., Carlson, J. H., McCarthy, J. B., Dorsam, G. P., & Schuh, J. M. (2015) · Immunobiology · doi:10.1016/j.imbio.2015.01.011 · Cited by 10

In SilicoPhylogenetic and Structural Analyses of Plant Endogenous Danger Signaling Molecules upon Stress

Pavlopoulou, A., Karaca, E., Balestrazzi, A., & Georgakilas, A. G. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/8683054 · Cited by 10

CD44 Can Compensate for IgSF11 Deficiency by Associating with the Scaffold Protein PSD-95 during Osteoclast Differentiation

Kim, H., Takegahara, N., Walsh, M. C., & Choi, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072646 · Cited by 10

Human mesenchymal stem cells respond differentially to platelet preparations and synthesize hyaluronic acid in nucleus pulposus extracellular matrix

Dregalla, R. C., Uribe, Y., & Bodor, M. (2020) · The Spine Journal · doi:10.1016/j.spinee.2020.06.011 · Cited by 10

Common Cosmetic Compounds Can Reduce Air Pollution-Induced Oxidative Stress and Pro-Inflammatory Response in the Skin

Hergesell, K., Valentová, K., Velebný, V., Vávrová, K., & Dolečková, I. (2022) · Skin Pharmacology and Physiology · doi:10.1159/000522276 · Cited by 10

Lovastatin Inhibits Low Molecular Weight Hyaluronan Induced Chemokine Expression via LFA-1 and Decreases Bleomycin-Induced Pulmonary Fibrosis

Hamblin, M. J., Eberlein, M. H., Black, K. E., Hallowell, R. W., Collins, S. L., Chan‐Li, Y., & Horton, M. R. (2014) · International Journal of Biomedical Science · doi:10.59566/ijbs.2014.10146 · Cited by 10

The effects of female sexual hormones on the endothelial glycocalyx

Potje, S. R., Martins, N. S., Benatti, M. N., Rodrigues, D., Bonato, V. L. D., & Tostes, R. C. (2023) · Current topics in membranes · doi:10.1016/bs.ctm.2023.02.005 · Cited by 9

Hyaluronate Protects From Benzalkonium Chloride-Induced Ocular Surface Toxicity

Vereertbrugghen, A., Pizzano, M., Sabbione, F., del Papa, M. S., Rodríguez, G., Passerini, M. S., & Galletti, J. G. (2024) · Translational Vision Science & Technology · doi:10.1167/tvst.13.10.31 · Cited by 9

Role of toll-like receptors in pulmonary immunity: mechanisms and therapeutic implications

Qu, Z., Guo, Z., Yang, C., Guan, X., Cheng, M., Wang, P., & Xu, D. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1682649 · Cited by 9

Matrix Regulation of Lung Injury, Inflammation, and Repair: The Role of Innate Immunity

Noble, P. W., & Jiang, D. (2006) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200604-097aw · Cited by 107

Matrix Regulation of Lung Injury, Inflammation, and Repair

Noble, P. W., & Jiang, D. (2012) · Proceedings of the American Thoracic Society · Cited by 1

Hyaluronan as an Immune Regulator in Human Diseases

Jiang, D., Liang, J., & Noble, P. W. (2011) · Physiological Reviews · doi:10.1152/physrev.00052.2009 · Cited by 1,060

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

Jiang, D., Liang, J., Fan, J., Yu, S., Chen, S., Luo, Y., Prestwich, G. D., Mascarenhas, M. M., Garg, H. G., Quinn, D. A., et al. (2005) · Nature Medicine · doi:10.1038/nm1315 · Cited by 1,401

Hyaluronan Fragments Stimulate Endothelial Recognition of Injury through TLR4

Taylor, K. R., Trowbridge, J. M., Rudisill, J. A., Termeer, C. C., Simon, J. C., & Gallo, R. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310859200 · Cited by 545