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Cited by 532

The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.

Applications of Acoustics and Cavitation to Noninvasive Therapy and Drug Delivery

Coussios, Constantin C., Roy, Ronald A.·2008·Annual Review of Fluid Mechanics

Abstract

Biomedical acoustics is rapidly evolving from a diagnostic modality into a therapeutic tool, and acoustic cavitation is often the common denominator in a wide range of new therapeutic applications. High-intensity focused ultrasound (HIFU) waves generated outside the body can be used to deposit heat deep within the body. Through a quantitative analysis of heat deposition by ultrasound, it is shown that inertial cavitation can help address some of the major challenges of HIFU therapy by providing a means of enhancing and monitoring treatment noninvasively. In the context of drug delivery, both inertial and stable cavitation play roles in enhancing drug activity and uptake. In particular, shape oscillations arising during stable cavitation provide an effective micropumping mechanism for enhanced mass transport across inaccessible interfaces.

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Crossref · 10.1146/annurev.fluid.40.111406.102116

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Metadata

Authors
Coussios, C. C., & Roy, R. A.
Venue
Annual Review of Fluid Mechanics
Published
2008-01-01
Volume
40
Issue
1
Pages
395-420
ISSN
  • 0066-4189 (ISSN-L)
  • 1545-4479
OpenAlex
W2012179147
Cited by
532
References
47
FWCI
0.98
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Applications of Acoustics and Cavitation to Noninvasive Therapy and Drug Delivery. https://app.cochat.ai/papers/10.1146/annurev.fluid.40.111406.102116
The paper
Coussios, C. C., & Roy, R. A. (2008). Applications of Acoustics and Cavitation to Noninvasive Therapy and Drug Delivery. Annual Review of Fluid Mechanics. https://doi.org/10.1146/annurev.fluid.40.111406.102116

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.