The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Translational Regulation and RNA Localization in Drosophila Oocytes and Embryos
Abstract
▪ Abstract Translational control is a prevalent means of gene regulation during Drosophila oogenesis and embryogenesis. Multiple maternal mRNAs are localized within the oocyte, and this localization is often coupled to their translational regulation. Subsequently, translational control allows maternally deposited mRNAs to direct the early stages of embryonic development. In this review we outline some general mechanisms of translational regulation and mRNA localization that have been uncovered in various model systems. Then we focus on the posttranscriptional regulation of four maternal transcripts in Drosophila that are localized during oogenesis and are critical for embryonic patterning: bicoid (bcd), nanos (nos), oskar (osk), and gurken (grk). Cis- and trans-acting factors required for the localization and translational control of these mRNAs are discussed along with potential mechanisms for their regulation.
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Cites
Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells
HSU, M.-T., & COCA-PRADOS, M. (1979) · Nature · doi:10.1038/280339a0 · Cited by 1,021
Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E.-M., & Mandelkow, E. (1997) · Cell · doi:10.1016/s0092-8674(00)80208-1 · Cited by 878
Cytoplasmic Polyadenylation in Development and Beyond
Richter, J. D. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.2.446-456.1999 · Cited by 299
Simon, R., Tassan, J. P., & Richter, J. D. (1992) · Genes & Development · doi:10.1101/gad.6.12b.2580 · Cited by 156
Fridell, R. A., Harding, L. S., Bogerd, H. P., & Cullen, B. R. (1995) · Virology · doi:10.1006/viro.1995.1266 · Cited by 129 · cited 1×
“This domain has not been assigned a molecular function, but it is present in several proteins implicated in RNA processing (64, 65, 207).”
BackgroundAudic, Y., Omilli, F., & Osborne, H. B. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.1.209 · Cited by 73
Cited by
BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
Bramham, C. R., & Messaoudi, E. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.06.003 · Cited by 1,193
mRNA localization: Gene expression in the spatial dimension
Martin, K. C., & Ephrussi, A. (2009) · Cell · doi:10.1016/j.cell.2009.01.044 · Cited by 1,048
Molecular mechanisms of translational control
Gebauer, F., & Hentze, M. W. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1488 · Cited by 991
Anderson, P., & Kedersha, N. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200512082 · Cited by 984
Mechanisms and Consequences of Alternative Polyadenylation
Di Giammartino, D. C., Nishida, K., & Manley, J. L. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.017 · Cited by 737
Metadata
- Authors
- Johnstone, O., & Lasko, P.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 2001-12
- Volume
- 35
- Issue
- 1
- Pages
- 365-406
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2166840544
- Cited by
- 322
- References
- 6
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- closed
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