Cited by 597Medicinal Plant ResearchMedicinal plant effects and applicationsNatural product bioactivities and synthesis

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New Substances of Plant Origin which Increase Nonspecific Resistance

Brekhman, I I, Dardymov, I V·1969·Annual Review of Pharmacology

DOI 10.1146/annurev.pa.09.040169.002223

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Effects of adaptogen supplementation on sport performance. A recent review of published studies
Domene, Á. M. (2013) · Journal of Human Sport and Exercise · doi:10.4100/jhse.2013.84.15 · Cited by 14
“…et al., 1968; Saratikov & Krasnov, 2004, Qian et al., 2012; Parisi, 2010; De Bock et al, 2004; Lee et al, 2009), Eleutherococcus senticosus (Brekhman & Dardymov, 1969; Kimura & Sumiyoshi, 2004; Huan & Rose, 2001) Schizandra chinensis (Hurynovicz et al., 1960; Panossian & Wikman, 2008),…”
BackgroundInfluential
Quality Characteristics and Antioxidant Activity of Yogurt Added with Acanthopanax Powder
Oh, H., & Kang, S.-T. (2015) · Korean Journal of Food Science and Technology · doi:10.9721/kjfst.2015.47.6.765 · Cited by 14
Effects of Acanthopanax senticosus (Rupr. & Maxim.) Harms on cerebral ischemia-reperfusion injury revealed by metabolomics and transcriptomics
Chen, R.-H., Du, W.-D., Wang, Q., Li, Z., Wang, D., Yang, S.-L., & Feng, Y. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113212 · Cited by 14
New Approaches to the Pharmacological Management of Major Depressive Disorder
Witkin, J. M., & Li, X. (2009) · Advances in pharmacology · doi:10.1016/s1054-3589(08)57009-8 · Cited by 14
Meta-analysis of Studies and Patents on Korean ginseng in Recent 5 Years in Korea and Prospective Needs
Park, S. (2006) · Journal of Ginseng Research · doi:10.5142/jgr.2006.30.4.212 · Cited by 14
The Systemic Theory of Living Systems and Relevance to CAM: The Theory (Part II)
Rangel, J. A. O. (2005) · Evidence-based Complementary and Alternative Medicine · doi:10.1093/ecam/neh093 · Cited by 14
Ocimum sanctum Linn. Extract Improves Cognitive Deficits in Olfactory Bulbectomized Mice via the Enhancement of Central Cholinergic Systems and VEGF Expression
Le, X. T., Nguyen, H. T., Nguyen, T. V., Pham, H. T. N., Nguyen, P. T., Nguyen, K. M., Nguyen, B. V., & Matsumoto, K. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/6627648 · Cited by 14
Rhodiola rosea (SHR-5), Part I
Ross, S. M. (2014) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000014 · Cited by 14
Stability Kinetics of Ginsenosides in Aqueous Solution
Miyamoto, E., Odashima, S., Kitagawa, I., et al. (1984) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600730334 · Cited by 13
Bronchodilatory activity of Curcuma longa, Zingiber officinale and Alpinia galanga based herbal formulation (AHF)
Dongre, P. R., Bhujbal, S. S., & Kumar, D. (2015) · Oriental Pharmacy and Experimental Medicine · doi:10.1007/s13596-015-0205-7 · Cited by 13
Adaptogens in chemobrain (Part III): Antitoxic effects of plant extracts towards cancer chemotherapy-induced toxicity - transcriptome-wide microarray analysis of neuroglia cells
Seo, E., Klauck, S. M., Efferth, T., & Panossian, A. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.11.011 · Cited by 14
Fermentation Characteristics of Yakju Added with Acanthopanacis cortex Extract
Kim, I. H., Kim, S. H., & Kwon, J. (2008) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2008.37.4.521 · Cited by 13
“또한 Brekhmann과 Dardymov(5)가 오가피 뿌리에서 lignan계 배당체 분리와 연구의 시작으로 인삼과 유사한 adaptogenic activity를 보 고하였고 관련 생리활성으로 항암작용(6), 항피로효과(7) 등 의 연구가 활발하게 진행되고 있다.”
Toxicological assessment of Aralia mandshurica (Araliaceae) root extract after subchronic administration in rats. A biochemical and histological study
Burgos, R. A., Hancke, J. L., Wikman, G., et al. (1994) · Phytotherapy Research · doi:10.1002/ptr.2650080102 · Cited by 13
Panax ginseng extract improves scopolamine‐induced deficits in working memory performance in the T‐maze delayed alternation task in rats
Ni, X.-H., Ohta, H., Watanabe, H., et al. (1993) · Phytotherapy Research · doi:10.1002/ptr.2650070112 · Cited by 13
Method Validation for the Determination of Eleutherosides and β-Glucan in Acanthopanax koreanum
Kim, Y.-H., Bae, D.-B., Park, S.-O., Lee, S.-J., Cho, O.-H., & Lee, O. (2013) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2013.42.9.1419 · Cited by 12
“분의 오가피속 식물과 다르게 탐라오가피는 eleutheroside B와 E가 함께 존재하는 것으로 알려져 있다(11,12).”
Recent Advances in Polysaccharides Derived from the Genus Panax: Preparation Strategies, Structural Profiles, Functional Properties and Structure–Activity Relationships
Bu, Y., Liu, Y., Zhu, L., Gan, X., Jiang, S., Zhang, X., Dilixiati, M., Bai, M., Zeng, J., Shi, S., et al. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c07918 · Cited by 12
Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event‐related potential dual task study
Koop, T., Dienel, A., Heldmann, M., & Münte, T. F. (2020) · Phytotherapy Research · doi:10.1002/ptr.6778 · Cited by 13
Stimulation of Growth Hormone Gene Expression in the Pituitary and Brain by Panax ginseng C. A. MEYER
Yoshizato, H., Fujikawa, T., Shibata, M., Tanaka, M., & Nakashima, K. (1999) · Endocrine Journal · doi:10.1507/endocrj.46.suppl_s85 · Cited by 12
Antiviral effect of flavonoids on the Dengue virus
S�nchez, I., G�mez-Garibay, F., Taboada, J., & Ruiz, B. H. (2000) · Phytotherapy Research · doi:10.1002/(sici)1099-1573(200003)14:2 · Cited by 129
Inhibition of histamine mediated responses byMirabilis jalapa: confirming traditional claims made about antiallergic and antiasthmatic activity
Maxia, A., Sanna, C., Salve, B., et al. (2010) · Natural Product Research · doi:10.1080/14786410802632804 · Cited by 12
“The eosinophile count was done in each group before drug administration and 24 h after buffalo milk injection (4mLkg 1, s.c.), as described by Brekhman and Dardymov (1969).”
Method
Traditional preparation of Phaleria nisidai, a Palauan tea, reduces exposure to toxic daphnane-type diterpene esters while maintaining immunomodulatory activity
Kulakowski, D., Kitalong, C., Negrin, A., Tadao, V., Balick, M. J., & Kennelly, E. J. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.06.023 · Cited by 12
Effects of Panax ginseng on Stress
이미정 (2008) · Journal of Ginseng Research · doi:10.5142/jgr.2008.32.1.008 · Cited by 12
Effects of red ginseng supplementation on aerobic.anaerobic performance, central and peripheral fatigue
윤성진 (2008) · Journal of Ginseng Research · doi:10.5142/jgr.2008.32.3.210 · Cited by 12
Ginseng Flowers Stimulate Progesterone Production from Bovine Luteal Cells
Wu, L., Sheu, S.-Y., Huang, C.-C., et al. (2000) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x0000043x · Cited by 12
BIOLOGICAL ACTIVE COMPONENTS OF SILENE TOMENTELLA AND THEIR PHARMACOLOGICAL PROPERTIES
Yusupova, U. Y., Ramazonov, N. S., Bobakulov, K. M., Эгамова, Ф. Р., Syrov, V. N., & Usmanov, D. A. (2021) · chemistry of plant raw material · doi:10.14258/jcprm.2021018323 · Cited by 12
Immunosuppressive activity of hexane and ethanolic extracts of Pterospermum acerifolium seeds in BALB/c mice
Pathak, M., Bano, N., Dixit, P., Soni, V. K., Kumar, P., Maurya, R., & Misra‐Bhattacharya, S. (2010) · Medicinal Chemistry Research · doi:10.1007/s00044-010-9476-1 · Cited by 11
“The concept of immunomodulation relates to non-specific activation of the function and efficiency of macrophages, granulocytes, complement, natural killer cells, lymphocytes and also to the production of various effector molecules generated by activated immune cells (Brekhman and Dardimov, 1969).”
Background
Behavioral and enzymatic bioassays with Serjania erecta Radlk., Sapindaceae, correlated with cognitive dysfunctions
Broggini, L. S. C., Fernandes, R. S., Nogueira, T., Suzano, F. R., Caetano, A. L., Buck, H. S., Couto, L. B., França, S. D. C., & Pereira, P. S. (2010) · Revista Brasileira de Farmacognosia · doi:10.1590/s0102-695x2010000400010 · Cited by 10
“…significant results in the acquisition, consolidation and evocation of memory (Kidd, 1999; Siripuraru et al. 2005), improvements in the sleep quality and in the sexual performance (Brekhman & Dardymov, 1969; Baranov, 1982) as well as normalization of acute and chronic stress in rodents (Rai, 2003).”
Background
Review of the molecular genetics in higher plants towards salidrosid and cinnamyl alcohol glycosides biosynthesis inRhodiola roseaL.
Mirmazloum, I., & György, Z. (2012) · Acta Alimentaria · doi:10.1556/aalim.41.2012.suppl.13 · Cited by 11
Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells
Seo, E., Klauck, S. M., Efferth, T., & Panossian, A. G. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.11.004 · Cited by 11
The Anti-Stress Potential of North American Ginseng (Panax quinquefoliusL.)
Awang, D. V. C. (1998) · Journal of Herbs Spices & Medicinal Plants · doi:10.1300/j044v06n02_11 · Cited by 11
Pharmacological activities onEphedra nebrodensisTineo
Ballero, M., Foddis, C., Sanna, C., et al. (2010) · Natural Product Research · doi:10.1080/14786410802680902 · Cited by 10
“Total leucocyte count was measured in each group before drug administration and 24 h after milk injection (Brekhman & Dardymov, 1969).”
BackgroundMethod
Modulation of lead toxicity bySpirulina fusiformis
Shastri, D., Kumar, M., & Kumar, A. (1999) · Phytotherapy Research · doi:10.1002/(sici)1099-1573(199905)13:3
Eleutheroside E, an active compound from Eleutherococcus senticosus, regulates adipogenesis in 3T3-L1 cells
Jung, C. H., Ahn, J., Heo, S. H., & Ha, T. Y. (2014) · Food Science and Biotechnology · doi:10.1007/s10068-014-0119-z · Cited by 10
“The stem of this plant used as an adaptogen for treatment of various ailments (1,2), contains pharmacologically active compounds, such as eleutherosides, vitamins, flavonoids, and complex polysaccharides (3).”
Background
13-Week repeated oral dose toxicity study on mixture of Korean red ginseng and deer antler extract in Sprague-Dawley rats
Suh, J. H., Seo, H. W., Han, B.-C., et al. (2019) · Toxicological Research · doi:10.1007/s43188-019-00005-5 · Cited by 10
Determination of Eleutherosides and β-Glucan Content from Different Parts and Cultivating Areas of A. senticosus and A. koreanum
Kim, Y. H., Bae, D.-B., Lee, J. S., 박선옥, Lee, S.-J., Cho, O.-H., & Lee, O. (2013) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2013.42.12.2082 · Cited by 10
Effect of traditionally designed nutraceutical on stress induced immunoglobulin changes at Antarctica
Bansal, P., Sannd, R., Srikanth, N., et al. (2009) · African Journal of Biochemistry Research · doi:10.5897/ajbr.9000095 · Cited by 10
“According to Brekhman and Dardymov (1969), an adaptogen must produce a nonspecific response that is, increase the power of resistance against multiple stressors.”
Background
Molecular Chaperones as Mediators of Stress Protective Effect of Plant Adaptogens
Panossian, A. G., Wikman, G., Kaur, P., & Asea, A. A. A. (2009) · Heat shock proteins · doi:10.1007/978-90-481-3381-9_20 · Cited by 10
“Adaptogens are medicinal plants that enhance the “state of non-specific resistance” of an organism to stress, augmenting resistance to physical, biological, chemical and psychological stresses, and increasing concentration, performance and endurance during fatigue (Brekhman and Dardymov, 1969; Panossian, 2003, 2005; P…”
Background
Efficacy of orally administered ginseng stem and leaf in chickens
Park, S., Lee, K.-Y., Cho, Y., et al. (2015) · Korean Journal of Veterinary Research · doi:10.14405/kjvr.2015.55.1.1 · Cited by 9
“인삼의 진세노사이드는 protopanaxatriol(PPT; Rg1, Re, Rf, Rh1, Rg2)계의 진세노 사이드와 protopanaxadiol(PPD; Rb1, Rc, Rb2, Rb3, Rd, Rg3, Rh2, Compound-K)계의 진세노사이드로 구성되어 있다 [3, 5].”
Protective Effects of Salidroside on Hypoxia/Reoxygenation Injury by Sodium Hydrosulfite in PC12 Cells
Chen, Z., Lü, Y., Wang, Z., et al. (2007) · Pharmaceutical Biology · doi:10.1080/13880200701538666 · Cited by 9
The Effects of Adaptogens on the Physical and Psychological Symptoms of Chronic Stress
Ajala, T. (2017) · DISCOVERY Georgia State Honors College Undergraduate Research Journal · doi:10.31922/disc4.2 · Cited by 10
“He describes them to stress (Brekhman & Dardymov, 1969).”
Effects of Eleutherococcus senticosus Cortex on Recovery from the Forced Swimming Test and Fatty Acid β-Oxidation in the Liver and Skeletal Muscle of mice
Sumiyoshi, M., & Kimura, Y. (2016) · The Natural Products Journal · doi:10.2174/2210315506999151207145020 · Cited by 10
“Brekhman and Dardmov [28] previously reported that the root bark of E. senticosus was used in Russia as an adaptogen, the properties of which increased non-specific body resistance to stress and fatigue.”
Background
Anti allergic and anti-inflammatory effects of the fruits of Randia dumetorum Lamk
Kumar, D., Mudgade, S. C., Bhat, Z. A., et al. (2011) · Oriental Pharmacy and Experimental Medicine · doi:10.1007/s13596-011-0025-3 · Cited by 9
“According to Brekhman and Dardymov (1969) the most important characteristic of an adaptogen, is that it increases resistance to adverse influences of a wide range of factors of physical, chemical and biological nature; and its normalization action, which reveals itself irrespective of the direction…”
BackgroundMethod
The Correct Name for Siberian Ginseng
Soejarto, D. D., & Farnsworth, N. R. (1978) · Botanical Museum leaflets Harvard University · doi:10.5962/p.295218 · Cited by 9
Effects of Murashige and Skoog medium strength on germination and secondary metabolites production of Eleutherococcus senticosus’s somatic embryos in bioreactor
(2013) · International Journal of Biosciences (IJB) · doi:10.12692/ijb/3.3.155-163 · Cited by 9
Ginseng saponin treatment does not alter brain or pituitary levels of beta-endorphin and dynorphin
Ho, W. K. K., Ng, T. B., Yeung, H. W., et al. (1985) · Biochemical Pharmacology · doi:10.1016/0006-2952(85)90334-x · Cited by 9
Agents that Increase Resistance to Diseases
Schulz, V., Hänsel, R., & Tyler, V. E. (2001) · Springer eBooks · doi:10.1007/978-3-642-98093-0_9 · Cited by 9
Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory cytokines/NF-KB signaling pathways
Oni, J. O., Oyenekan, D. O., Olayemi, Y. O., Irabor, O. C., Ogbuji, P., Tova, M. O., Adeleke, P. A., Abbas, G. A., & Umukoro, S. (2025) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2025.100578 · Cited by 8
Eleutherococcus root: a comprehensive review of its phytochemistry and pharmacological potential in the context of its adaptogenic effect
Patyra, A., Kołtun-Jasion, M., Kupniewska, K., Parzonko, A., & Kiss, A. K. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1683795 · Cited by 10
The Pharmacological Action of Common Herbal Remedies
Bhikha, R. (2018) · American Journal of Internal Medicine · doi:10.11648/j.ajim.20180605.13 · Cited by 8
“[15] When used by herbalists, the term refers to herbs which are more popularly known as tonics, agents which have a rejuvenating effect.”
Background
Special Feature
Mitra, R., Mitchell, B., Agricola, S., Gray, C., Baskaran, K., & Muralitharan, M. (2007) · Asia-Pacific Biotech News · doi:10.1142/s0219030307000730 · Cited by 8
Potential of some traditionally used edible plants for prevention and cure of diabesity associated comorbidities
Kumar, V., Thakur, A. K., Verma, S., Yadav, V., & Chatterjee, S. S. (2015) · TANG [HUMANITAS MEDICINE] · doi:10.5667/tang.2014.0026 · Cited by 8
Resistance for Strength
Ross, S. M. (2020) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000408 · Cited by 9
Clinician perspectives and understanding of the adaptogenic concept: A focus group study with Naturopaths and Western Herbalists
Gerontakos, S., Casteleijn, D., & Wardle, J. (2020) · Integrative Medicine Research · doi:10.1016/j.imr.2020.100433 · Cited by 8
Evaluation of Anti-Asthmatic Activity of Ethanolic Extract of Argemone mexicana Stems
Singh, R. M., Chaubey, N., & Mishra, R. K. (2021) · Saudi Journal of Medical and Pharmaceutical Sciences · doi:10.36348/sjmps.2021.v07i01.007 · Cited by 8
“Neuber’s chamber was charged with above fluid and eosinophil count was done [16].”
Method
Trait Energy and Fatigue Modify Acute Ingestion of an Adaptogenic-Rich Beverage on Neurocognitive Performance
Boolani, A., Fuller, D. T., Mondal, S., & Gumpricht, E. (2022) · Applied Sciences · doi:10.3390/app12094466 · Cited by 8
An unique solvent assisted ‘green’ hydrotropic precipitation and response surface optimization for isolation of the dietary micronutrient β-sitosterol- d -glucopyranoside from Desmostachya bipinnata
Subramaniam, S., Palanisamy, A., & Sivasubramanian, A. (2014) · RSC Advances · doi:10.1039/c4ra13923b · Cited by 8
Differential effects of Rhodiola rosea on regulatory T cell differentiation and interferon-γ production in vitro and in vivo
Xu, X., Li, P., Zhang, P., Chu, M., Liu, H., Chen, X., & Ge, Q. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5278 · Cited by 8
“Greater than 20 compounds are present in the R. rosea root, including salidroside (rhodioloside), rosavins and p-tyrosol, which are understood to have important therapeutic activities (2).”
The liquorice root derivative glycyrrhetinic acid can ameliorate ionoregulatory disturbance in rainbow trout ( Oncorhynchus mykiss ) abruptly exposed to ion-poor water
Chen, C. C., Kolosov, D., & Kelly, S. P. (2016) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2016.05.020 · Cited by 8
SCREENING FOR ANTI-INFLAMMATORY AND ANTI-ALLERGIC ACTIVITY OF BHARANGI {CLERODENDRUM SERRRATUM (LINN.) MOON} IN ANIMALS
N.K.Bhangare, Pansare, T. A., Ghongane, B. B., et al. (2012) · Cited by 8
Effect of Acanthopanax senticosus Extracts on Alcohol Degradation and Anti-Inflammatory Activity in Mice
Yoon, T. J., & Jo, S. Y. (2010) · The Korean Journal of Food And Nutrition · Cited by 8
Nutraceuticals: New Era of Medicine and Health
-, P. J., -, L. K., & -, S. K. (2023) · International Journal For Multidisciplinary Research · doi:10.36948/ijfmr.2023.v05i04.5788 · Cited by 8
Protective effects ofAcanthopanax divaricatusextract in mouse models of Alzheimer's disease
Yan, J.-J., Ahn, W.-G., Jung, J., Kim, H., Hasan, M. A., & Song, D. (2014) · Nutrition Research and Practice · doi:10.4162/nrp.2014.8.4.386 · Cited by 9
“Acanthopanax, which has been regarded as having ginseng like activity, has been known as an adaptogen [7], and has been used in the Far East in treatment of various disorders, including stress-induced physiological changes, inflammation, hypertension, and cancer [8].”
Background
The Effects on the Blood Lipid Profiles and Body Fat by Long Term Administration of Red Ginseng Product
김성수 (2002) · Journal of Ginseng Research · doi:10.5142/jgr.2002.26.2.067 · Cited by 8
Anti-inflammatory and anti-nociceptive activities of methanolic leaf extract of Indigofera cassioides Rottl. Ex. DC.
Kumar, R. S., Balasubramanian, R., & Perumal, P. (2013) · Journal of Acute Disease · doi:10.1016/s2221-6189(13)60152-3 · Cited by 8
“In Indian system of medicine, a large number of drugs from herbal or mineral origin have been advocated for various types of diseases and other different unwanted conditions in humans[1].”
Background
Drug-biomacromolecule interaction I
Kim, C., & Ahn, H. Y. (1981) · Archives of Pharmacal Research · doi:10.1007/bf02855752 · Cited by 8
Inhibitory effect of arginine-derivatives from ginseng extract and basic amino acids on protein-arginine N-methyltransferase
Yool, B. C., Park, G. H., Okuda, H., et al. (1999) · Amino Acids · doi:10.1007/bf01361664 · Cited by 8
“Several active compounds extracted from ginseng have been characterized to be consistently effective on the cardiovascular and central nervous systems (Brekhman and Dardymov, 1969) and also as an antioxidant (Kim et al.”
Background
Synthesis and Pharmacological Activity of Aminoketones and Aminoalcohols of the Imidazo[1,2-a]benzimidazole Series
Анисимова, В. А., Avdyunina, N. I., Спасов, А. А., et al. (2002) · Pharmaceutical Chemistry Journal · doi:10.1023/a:1021096114589 · Cited by 8
Eleutherococcus Senticosus
Sonnenbora, U., & Hänsel, R. (1993) · Adverse effects of herbal drugs · doi:10.1007/978-3-642-48906-8_12 · Cited by 8
The Acute Effects of a Multi-Ingredient Herbal Supplement on Performance Fatigability: A Double-Blind, Randomized, and Placebo-Controlled Trial
Ryan, E. D., Gerstner, G. R., Mota, J. A., Trexler, E. T., Giuliani, H. K., Blue, M. N. M., Hirsch, K. R., & Smith-Ryan, A. E. (2021) · Journal of Dietary Supplements · doi:10.1080/19390211.2020.1790709 · Cited by 7
“Interestingly, previous authors (Kokoska and Janovska 2009; Brekhman and Dardymov 1969) have suggested RCE is an adaptogen which may also improve fatigue resistance, although we are unaware of any previous studies that have examined the influence of acute RCE supplementation on performance…”
Background
Effects of an herbal adaptogen feed-additive on feeding-related hypothalamic neuropeptides in chronic cyclic heat-stressed chickens
Greene, E. S., Ardakani, M. A., & Dridi, S. (2024) · Neuropeptides · doi:10.1016/j.npep.2024.102439 · Cited by 7
Isolation and Identification of α-Glucosidase Inhibitory Compounds, Hyperoside, and Isoquercetin from Eleutherococcus senticosus Leaves
Lee, K. Y., Hong, S. Y., Jeong, H. J., et al. (2014) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2014.43.12.1858 · Cited by 7
Preparation of Functional Healthy Drinks by Acanthopanax senticosus Extracts
Sung, M.-S., Jung, H., Choi, J.-H., et al. (2014) · Journal of Life Science · doi:10.5352/jls.2014.24.9.959 · Cited by 7
“저하, 전립선 기능 강화, 간 기능 개선, 항암효과[4, 12]와, eleutheroside B의 골질환 예방, 항산화 활성, 항암작용, 항스 트레스 작용, 항피로작용 등이 알려져 있다[40].”
Influential
Development of Functional Food Materials from Acanthopanax senticosus-Fermented Mushroom Mycelia
Cho, J., Choi, G.-H., Park, I.-J., et al. (2014) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2014.43.3.411 · Cited by 7
Immunomodulatory Activity of Bioactive Fraction (PBC) from Phyllostachys bambusoides
Kumar, S., Sharma, G., & Kumar, A. (2017) · Pharmacognosy Journal · doi:10.5530/pj.2017.6.123 · Cited by 7
Antioxidant, anti-inflammatory, and adaptogenic activity of Asparagus acutifolius extract
Kasture, S. B., Kasture, A. S., Ballero, M., et al. (2009) · Oriental Pharmacy and Experimental Medicine · doi:10.3742/opem.2009.9.1.083 · Cited by 7
“After 24 h the leukocyte count was repeated as described by Brekhman and Dardymove (1969).”
BackgroundMethod
Analysis of the Effective Fraction of Sun Ginseng Extract in Selenite Induced Cataract Rat Model
Lee, S. M., Sun, J. M., Jeong, J. H., et al. (2010) · Journal of the Korean Ophthalmological Society · doi:10.3341/jkos.2010.51.5.733 · Cited by 7
ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ETHANOL EXTRACT OF INDIGOFERA TRITA LINN.
Kumar, R., Balasubramanian, R., Perumal, P., et al. (2009) · Cited by 7
Chemical Investigation of the Crude Drugs Stored in Shosoin for over Twelve Hundred Years
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Authors: Brekhman, I. I., & Dardymov, I. V.
Venue: Annual Review of Pharmacology
Publisher: Annual Reviews
Published: 1969-04
Volume: 9
Issue: 1
Pages: 419-430
ISSN: 0066-4251 (ISSN-L)
DOI: 10.1146/annurev.pa.09.040169.002223
OpenAlex: W2102596758
Cited by: 595
References: 0
Citations by year: 2026: 7 · 2025: 11 · 2024: 12 · 2023: 19 · 2022: 12 · 2021: 24 · 2020: 27 · 2019: 6 · 2018: 18 · 2017: 15 · 2016: 10 · 2015: 15 · 2014: 23 · 2013: 24 · 2012: 26
FWCI: 1.45
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Pharmacology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Health Sciences › Medicine › Complementary and alternative medicine › Medicinal plant effects and applications
Physical Sciences › Chemistry › Organic Chemistry › Natural product bioactivities and synthesis
Keywords: plant extracts, non-specific immunity, immunostimulants, phytochemicals, host defense
MeSH terms: Animals, Chemistry, Drug Resistance, Microbial, Glycosides, Nucleic Acids, Plant Extracts, Plants, Protein Biosynthesis, Mice, Chemical Phenomena

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