Identification and Rational Design of Novel Antimicrobial Peptides for Plant Protection

Antimicrobial peptides of multicellular organisms

Zasloff, M. (2002) · Nature · doi:10.1038/415389a · Cited by 8,457

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

Brogden, K. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1098 · Cited by 5,829

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies

Hancock, R. E. W., & Sahl, H. (2006) · Nature Biotechnology · doi:10.1038/nbt1267 · Cited by 4,301

Significance of Inducible Defense-related Proteins in Infected Plants

van Loon, L. C., Rep, M., & Pieterse, C. M. J. (2006) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.44.070505.143425 · Cited by 3,401

Mechanisms of Antimicrobial Peptide Action and Resistance

Yeaman, M. R., & Yount, N. Y. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.1.2 · Cited by 2,998

Peptide Antimicrobial Agents

Jenssen, H., Hamill, P., & Hancock, R. E. W. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00056-05 · Cited by 2,605

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

Vivès, É., Brodin, P. M., & Lebleu, B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.25.16010 · Cited by 2,440

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

Schwarze, S. R., Ho, A. L., Vocero-Akbani, A. M., & Dowdy, S. F. (1999) · Science · doi:10.1126/science.285.5433.1569 · Cited by 2,418

Bacteriocins: Developing innate immunity for food

Cotter, P. D., Hill, C., & Ross, R. P. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1273 · Cited by 2,380

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.

Zasloff, M. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.15.5449 · Cited by 2,305

The third helix of the Antennapedia homeodomain translocates through biological membranes.

Derossi, D., Joliot, A., Chassaing, G., & Prochiantz, A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34080-2 · Cited by 2,034

Diversity of antimicrobial peptides and their mechanisms of action

Epand, R. M., & Vogel, H. J. (1999) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(99)00198-4 · Cited by 1,354

Cationic peptides: a new source of antibiotics

Hancock, R. E. W., & Lehrer, R. I. (1998) · Trends in biotechnology · doi:10.1016/s0167-7799(97)01156-6 · Cited by 1,341

The co-evolution of host cationic antimicrobial peptides and microbial resistance

Peschel, A., & Sahl, H. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1441 · Cited by 1,076

Tryptophan- and arginine-rich antimicrobial peptides: Structures and mechanisms of action

Chan, D. I., Prenner, E. J., & Vogel, H. J. (2006) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2006.04.006 · Cited by 1,070

A peptide carrier for the delivery of biologically active proteins into mammalian cells

Morris, M. C., Depollier, J., Méry, J., Heitz, F., & Divita, G. (2001) · Nature Biotechnology · doi:10.1038/nbt1201-1173 · Cited by 1,019

Inactivation of the dlt Operon inStaphylococcus aureus Confers Sensitivity to Defensins, Protegrins, and Other Antimicrobial Peptides

Peschel, A., Otto, M. J., Jack, R. W., Kalbacher, H., Jung, G., & Götz, F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.13.8405 · Cited by 999

Cationic peptides: effectors in innate immunity and novel antimicrobials

Hancock, R. E. (2001) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(01)00092-5 · Cited by 978

The relationship between peptide structure and antibacterial activity

Powers, J.-P. S., & Hancock, R. E. W. (2003) · Peptides · doi:10.1016/j.peptides.2003.08.023 · Cited by 947

Mode of action of linear amphipathic α-helical antimicrobial peptides

Ziv, O., & Shai, Y. (1998) · Biopolymers · doi:10.1002/(sici)1097-0282(1998)47:6 · Cited by 857

Use of the Cell Wall Precursor Lipid II by a Pore-Forming Peptide Antibiotic

Breukink, E. J., Wiedemann, I., van Kraaij, C., Kuipers, O. P., Sahl, H., & KRUIJFF, B. D. (1999) · Science · doi:10.1126/science.286.5448.2361 · Cited by 815

Mechanism of Interaction of Different Classes of Cationic Antimicrobial Peptides with Planar Bilayers and with the Cytoplasmic Membrane of Escherichia coli

Wu, M., Maier, E., Benz, R., & Hancock, R. E. W. (1999) · Biochemistry · doi:10.1021/bi9826299 · Cited by 737

Lactoferrin—a multifunctional protein with antimicrobial properties

Farnaud, S., & Evans, R. W. (2003) · Molecular Immunology · doi:10.1016/s0161-5890(03)00152-4 · Cited by 731

Antimicrobial Peptides from Plants

Broekaert, W. F., Cammue, B. P. A., Bolle, M. F. C. D., Thevissen, K., Samblanx, G. W. D., Osborn, R. W., & Nielson, K. (1997) · Critical Reviews in Plant Sciences · doi:10.1080/07352689709701952 · Cited by 678

All-D amino acid-containing channel-forming antibiotic peptides.

Wade, D. C., Boman, A., Wåhlin, B., Drain, C. M., Andreu, D., Boman, H. G., & Merrifield, R. B. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4761 · Cited by 677

Plant defensins

Thomma, B. P. H. J., Cammue, B. P. A., & Thevissen, K. (2002) · Planta · doi:10.1007/s00425-002-0902-6 · Cited by 662

Melittin: a Membrane-active Peptide with Diverse Functions

Raghuraman, H., & Chattopadhyay, A. (2006) · Bioscience Reports · doi:10.1007/s10540-006-9030-z · Cited by 652

Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine

Boman, H. G., Agerberth, B., & Boman, A. (1993) · Infection and Immunity · doi:10.1128/iai.61.7.2978-2984.1993 · Cited by 559

Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase

Bader, M. W., Sanowar, S., Daley, M. E., Schneider, A. R., Cho, U., Xu, W., Klevit, R. E., Moual, H. L., & Miller, S. I. (2005) · Cell · doi:10.1016/j.cell.2005.05.030 · Cited by 554

Lactoferricin

Gifford, J. L., Hunter, H. N., & Vogel, H. J. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-005-5373-z · Cited by 529

Transduction peptides: from technology to physiology

Joliot, A., & Prochiantz, A. (2004) · Nature Cell Biology · doi:10.1038/ncb0304-189 · Cited by 495

Mechanism of antimicrobial action of indolicidin

Subbalakshmi, C., & Sitaram, N. (1998) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1998.tb12896.x · Cited by 481

Fungal pathogen protection in potato by expression of a plant defensin peptide

Gao, A.-G., Hakimi, S. M., Mittanck, C. A., Wu, Y., Woerner, B. M., Stark, D. M., Shah, D. M., Liang, J., & Rommens, C. M. T. (2000) · Nature Biotechnology · doi:10.1038/82436 · Cited by 472

Small cysteine‐rich peptides resembling antimicrobial peptides have been under‐predicted in plants

Silverstein, K. A. T., Moskal, W. A., Wu, H. C., Underwood, B. A., Graham, M. A., Town, C. D., & VandenBosch, K. A. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03136.x · Cited by 470

Apidaecins: antibacterial peptides from honeybees.

Casteels, P., Ampè, C., Jacobs, F. H. H., Vaeck, M., & Tempst, P. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08368.x · Cited by 469

Mode of Action of the Antimicrobial Peptide Indolicidin

Falla, T. J., Karunaratne, D. N., & Hancock, R. E. W. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.32.19298 · Cited by 467

Potent Antibacterial Peptides Generated by Pepsin Digestion of Bovine Lactoferrin

TOMITA, M., Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., & Kawase, K. (1991) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(91)78608-6 · Cited by 445

Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL‐37

Schmidtchen, A., Frick, I.-M., Andersson, E., Tapper, H., & Björck, L. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.03146.x · Cited by 440

An automated quantitative assay for fungal growth inhibition

Broekaert, W. F., Terras, F. R. G., Cammue, B. P. A., & Vanderleyden, J. (1990) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1990.tb04174.x · Cited by 438

Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa

McPhee, J. B., Lewenza, S., & Hancock, R. E. W. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03673.x · Cited by 436

Cell-penetrating peptides and antimicrobial peptides: how different are they?

Henriques, S. T., Melo, M. N., & Castanho, M. A. R. B. (2006) · Biochemical Journal · doi:10.1042/bj20061100 · Cited by 433

Permeabilization of Fungal Membranes by Plant Defensins Inhibits Fungal Growth

Thevissen, K., Terras, F. R. G., & Broekaert, W. F. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.12.5451-5458.1999 · Cited by 388

Antimicrobial peptides and plant disease control

Montesinos, E. (2007) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.00683.x · Cited by 376

Defensins from Insects and Plants Interact with Fungal Glucosylceramides

Thevissen, K., Warnecke, D. C., François, I., Leipelt, M., Heinz, E., Ott, C., Zähringer, U., Thomma, B. P. H. J., Ferket, K. K. A., & Cammue, B. P. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m311165200 · Cited by 355

Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA

Hsu, C. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki725 · Cited by 337

Translocation of a Channel-Forming Antimicrobial Peptide, Magainin 2, across Lipid Bilayers by Forming a Pore

Matsuzaki, K., Murase, O., Fujii, N., & Miyajima, K. (1995) · Biochemistry · doi:10.1021/bi00019a033 · Cited by 308

A Novel Antimicrobial Peptide fromBufo bufo gargarizans

Park, C. B., Kim, M. S., & Kim, S. C. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.0071 · Cited by 301

Expression of an Antimicrobial Peptide via the Chloroplast Genome to Control Phytopathogenic Bacteria and Fungi

DeGray, G., Rajasekaran, K., Smith, F., Sanford, J., & Daniell, H. (2001) · Plant Physiology · doi:10.1104/pp.010233 · Cited by 299

Antimicrobial Peptides, Isolated from Horseshoe Crab Hemocytes, Tachyplesin II, and Polyphemusins I and II: Chemical Structures and Biological Activity1

Miyata, T., Tokunaga, F., Yoneya, T., Yoshikawa, K., Iwanaga, S., Niwa, M., Takao, T., & Shimonishi, Y. (1989) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a122913 · Cited by 294

A linguistic model for the rational design of antimicrobial peptides

Loose, C. R., Jensen, K. L., Rigoutsos, I., & Stephanopoulos, G. N. (2006) · Nature · doi:10.1038/nature05233 · Cited by 248

Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens

Osusky, M., Zhou, G., Osuska, L., Hancock, R. E. W., Kay, W. W., & Misra, S. (2000) · Nature Biotechnology · doi:10.1038/81145 · Cited by 246

Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium.

Parra-Lopez, C., Baer, M. T., & Groisman, E. A. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06089.x · Cited by 230

Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibiotics.

Lohner, K., & Blondelle, S. (2005) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207053764576 · Cited by 222

Enhanced tolerance to bacterial pathogens caused by the transgenic expression of barley lipid transfer protein LTP2

Molina, A., & García‐Olmedo, F. (1997) · The Plant Journal · doi:10.1046/j.1365-313x.1997.00669.x · Cited by 216

Polarity in filamentous fungi: moving beyond the yeast paradigm

Harris, S. D., & Momany, M. (2003) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2003.11.007 · Cited by 210

Structure-Based Design of an Indolicidin Peptide Analogue with Increased Protease Stability ,

Rozek, A., Powers, J.-P. S., Friedrich, C. L., & Hancock, R. E. W. (2003) · Biochemistry · doi:10.1021/bi035643g · Cited by 207

Expression of the α‐thionin gene from barley in tobacco confers enhanced resistance to bacterial pathogens

Carmona, M. J., Molina, A., Fernández, J. A., López‐Fando, J. J., & García‐Olmedo, F. (1993) · The Plant Journal · doi:10.1111/j.1365-313x.1993.tb00165.x · Cited by 205

The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides

Dorschner, R. A., López‐García, B., Peschel, A., Kraus, D., Morikawa, K., Nizet, V., & Gallo, R. L. (2006) · The FASEB Journal · doi:10.1096/fj.05-4406com · Cited by 191

Interactions of antifungal plant defensins with fungal membrane components

Thevissen, K., Ferket, K. K. A., François, I., & Cammue, B. P. A. (2003) · Peptides · doi:10.1016/j.peptides.2003.09.014 · Cited by 187

Cyclization Increases the Antimicrobial Activity and Selectivity of Arginine- and Tryptophan-Containing Hexapeptides

Dathe, M., Nikolenko, H., Klose, J., & Bienert, M. (2004) · Biochemistry · doi:10.1021/bi035948v · Cited by 186

Recombinant production of antimicrobial peptides in heterologous microbial systems

Ingham, A. B., & Moore, R. J. (2007) · Biotechnology and Applied Biochemistry · doi:10.1042/ba20060207 · Cited by 176

A library of linear undecapeptides with bactericidal activity against phytopathogenic bacteria

Badosa, E., Ferré, R., Planas, M., Feliu, L., Besalú, E., Cabrefiga, J., Bardajı́, E., & Montesinos, E. (2007) · Peptides · doi:10.1016/j.peptides.2007.09.010 · Cited by 173

MSI-99, a magainin analogue, imparts enhanced disease resistance in transgenic tobacco and banana

Chakrabarti, A. K., Ganapathi, T. R., Mukherjee, P. K., & Bapat, V. A. (2002) · Planta · doi:10.1007/s00425-002-0918-y · Cited by 172

Improvement of outer membrane-permeabilizing and lipopolysaccharide-binding activities of an antimicrobial cationic peptide by C-terminal modification

Piers, K. L., Brown, M. H., & Hancock, R. E. W. (1994) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.38.10.2311 · Cited by 167

Antifungal Pisum sativum Defensin 1 Interacts with Neurospora crassa Cyclin F Related to the Cell Cycle

Lobo, D. S., Pereira, I. B., Madeira, L. F., de Medeiros, L. N., Cabral, L. M., Faria, J., Bellio, M., Campos, R. C., Linden, R., & Kurtenbach, E. (2007) · Biochemistry · doi:10.1021/bi061441j · Cited by 165

Heterologous Expression of Genes Mediating Enhanced Fungal Resistance in Transgenic Wheat

Oldach, K., Becker, D., & Lörz, H. (2001) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2001.14.7.832 · Cited by 165

Expression of a Cecropin B lytic peptide analog in transgenic tobacco confers enhanced resistance to bacterial wilt caused by Pseudomonas solanacearum

Jaynes, J. M., Nagpala, P., Destéfano‐Beltrán, L., Huang, J. H., Kim, J., Denny, T. P., & Çetiner, S. (1993) · Plant Science · doi:10.1016/0168-9452(93)90169-z · Cited by 161

Cecropin A—Derived Peptides Are Potent Inhibitors of Fungal Plant Pathogens

Cavallarin, L., Andreu, D., & Segundo, B. S. (1998) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.1998.11.3.218 · Cited by 153

Stress proteins on the yeast cell surface determine resistance to osmotin, a plant antifungal protein

Yun, D., Zhao, Y., Pardo, J. M., Narasimhan, M. L., Damsz, B., Lee, H., Abad, L. R., D’Urzo, M. P., Hasegawa, P. M., & Bressan, R. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.13.7082 · Cited by 152

Antimicrobial Peptides from Food Proteins

Pellegrini, A. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033454865 · Cited by 144

Design of self-processing antimicrobial peptides for plant protection

Powell, W. A., Catranis, C. M., & Maynard, C. A. (2000) · Letters in Applied Microbiology · doi:10.1046/j.1365-2672.2000.00782.x · Cited by 143

Transgenic expression of a gene encoding a synthetic antimicrobial peptide results in inhibition of fungal growth in vitro and in planta

Cary, J. W., Rajasekaran, K., Jaynes, J. M., & Cleveland, T. E. (2000) · Plant Science · doi:10.1016/s0168-9452(00)00189-8 · Cited by 136

Two mitogen-activated protein kinase signalling cascades mediate basal resistance to antifungal plant defensins in Fusarium graminearum

Ramamoorthy, V., Zhao, X., Snyder, A. K., Xu, J., & Shah, D. M. (2007) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00887.x · Cited by 136

Membrane Translocation Mechanism of the Antimicrobial Peptide Buforin 2

Kobayashi, S., Chikushi, A., Tougu, S., Imura, Y., Nishida, M., Yano, Y., & Matsuzaki, K. (2004) · Biochemistry · doi:10.1021/bi048206q · Cited by 135

Apidaecin-Type Peptide Antibiotics Function through a Nonporeforming Mechanism Involving Stereospecificity

Casteels, P., & Tempst, P. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.1234 · Cited by 134

Enhanced resistance to the rice blast fungus Magnaporthe grisea conferred by expression of a cecropin A gene in transgenic rice

Coca, M. A., Peñas, G., Gómez‐Ariza, J., Campo, S., Bortolotti, C., Messeguer, J., & Segundo, B. S. (2005) · Planta · doi:10.1007/s00425-005-0069-z · Cited by 134

Inactivation of the sapA to sapF Locus of Erwinia chrysanthemi Reveals Common Features in Plant and Animal Bacterial Pathogenesis

López‐Solanilla, E., García‐Olmedo, F., & Rodríguez‐Palenzuela, P. (1998) · The Plant Cell · doi:10.1105/tpc.10.6.917 · Cited by 129

Transgenic expression of cecropin B, an antibacterial peptide from Bombyx mori, confers enhanced resistance to bacterial leaf blight in rice

Sharma, A. K., Sharma, R., Imamura, M., Yamakawa, M., & Machii, H. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)02106-2 · Cited by 128

The antimicrobial peptides lactoferricin B and magainin 2 cross over the bacterial cytoplasmic membrane and reside in the cytoplasm

Haukland, H. H., Ulvatne, H., Sandvik, K., & Vorland, L. H. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03100-3 · Cited by 128

Improved activity of a synthetic indolicidin analog

Falla, T. J., & Hancock, R. E. W. (1997) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.41.4.771 · Cited by 127

Lactoferricin B inhibits bacterial macromolecular synthesis in and

Ulvatne, H., Samuelsen, Ø., Haukland, H. H., KRAMER, M., & Vorland, L. H. (2004) · FEMS Microbiology Letters · doi:10.1016/j.femsle.2004.07.001 · Cited by 122

Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects

Palm‐Apergi, C., Netzereab, S., & Hällbrink, M. (2006) · Peptides · doi:10.1016/j.peptides.2006.01.006 · Cited by 122

Antibiotic activities of peptides, hydrogen peroxide and peroxynitrite in plant defence

García‐Olmedo, F., Rodríguez‐Palenzuela, P., Molina, A., Alamillo, J. M., López‐Solanilla, E., Berrocal‐Lobo, M., & Poza‐Carrión, C. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02456-5 · Cited by 115

Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge

Steffen, H. K., Rieg, S., Wiedemann, I., Kalbacher, H., Deeg, M., Sahl, H., Peschel, A., Götz, F., Garbe, C., & Schittek, B. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00181-06 · Cited by 114

The Antifungal Protein from Aspergillus giganteus Causes Membrane Permeabilization

Theis, T., Wedde, M., Meyer, V., & Ståhl, U. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.2.588-593.2003 · Cited by 113

Expression of an Engineered Cecropin Gene Cassette in Transgenic Tobacco Plants Confers Disease Resistance to Pseudomonas syringae pv. tabaci

Huang, Y. P., Nordeen, R. O., Di, M., Owens, L. D., & McBeath, J. H. (1997) · Phytopathology · doi:10.1094/phyto.1997.87.5.494 · Cited by 113

Process development and economic evaluation of recombinant human lactoferrin expressed in rice grain

Nandi, S., Yalda, D., Lu, S. M., Nikolov, Z. L., Misaki, R., Fujiyama, K., & Huang, N. (2005) · Transgenic Research · doi:10.1007/s11248-004-8120-6 · Cited by 112

Inhibition of Plant-Pathogenic Bacteria by Short Synthetic Cecropin A-Melittin Hybrid Peptides

Ferré, R., Badosa, E., Feliu, L., Planas, M., Montesinos, E., & Bardajı́, E. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.5.3302-3308.2006 · Cited by 112

Structure and Function of Membrane-Lytic Peptides

Bechinger, B. (2004) · Critical Reviews in Plant Sciences · doi:10.1080/07352680490452825 · Cited by 111

Fungicidal activity of cecropin A

DeLucca, A. J., Bland, J. M., Jacks, T. J., Grimm, C. C., Cleveland, T. E., & Walsh, T. J. (1997) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.41.2.481 · Cited by 109

Enhanced disease resistance conferred by expression of an antimicrobial magainin analog in transgenic tobacco

Li, Q. Q., Lawrence, C. B., Hong-yan, X., Babbitt, R. A., Bass, W. T., Maiti, I. B., & Everett, N. P. (2001) · Planta · doi:10.1007/s004250000480 · Cited by 109

A pathogenesis related protein, AhPR10 from peanut: an insight of its mode of antifungal activity

Chadha, P., & Das, R. H. (2006) · Planta · doi:10.1007/s00425-006-0344-7 · Cited by 109

Disease resistance conferred by the expression of a gene encoding a synthetic peptide in transgenic cotton ( Gossypium hirsutum L.) plants

Rajasekaran, K., Cary, J. W., Jaynes, J. M., & Cleveland, T. E. (2005) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2005.00145.x · Cited by 107

Transgenic Potatoes Expressing a Novel Cationic Peptide are Resistant to Late Blight and Pink Rot

Osusky, M., Osuska, L., Hancock, R. E. W., Kay, W. W., & Misra, S. (2004) · Transgenic Research · doi:10.1023/b:trag.0000026076.72779.60 · Cited by 106

Antimicrobial Peptides

Rao, A. G. (1995) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi-8-0006 · Cited by 106

Aliphatic propargylamines: New antiapoptotic drugs

Boulton, A. A., Davis, B. A., Durden, D. A., Dyck, L. E., Juorio, A. V., Li, X., Paterson, I. A., & Yu, P. H. (1997) · Drug Development Research · doi:10.1002/(sici)1098-2299(199711/12)42:3/4 · Cited by 103

Cloning, structural organization and regulation of expression of the Penicillium chrysogenum paf gene encoding an abundantly secreted protein with antifungal activity

Marx, F., Haas, H., Reindl, M., Stöffler, G., Lottspeich, F., & Redl, B. (1995) · Gene · doi:10.1016/0378-1119(95)00701-6 · Cited by 102

The Antifungal Protein AFP from Aspergillus giganteus Inhibits Chitin Synthesis in Sensitive Fungi

Hagen, S., Marx, F., Ram, A. F. J., & Meyer, V. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02497-06 · Cited by 102

Purification, characterization, and cell wall localization of an α‐fucosidase that inactivates a xyloglucan oligosaccharin

Augur, C., Benhamou, N., Darvill, A. G., & Albersheim, P. (1993) · The Plant Journal · doi:10.1046/j.1365-313x.1993.t01-24-00999.x · Cited by 102

Identification of Novel Hexapeptides Bioactive against Phytopathogenic Fungi through Screening of a Synthetic Peptide Combinatorial Library

López‐García, B., Pérez‐Payá, E., & Marcos, J. F. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.5.2453-2460.2002 · Cited by 102

Expression of giant silkmoth cecropin B genes in tobacco

Florack, D. E. A., Allefs, S. J. H. M., Bollen, R., Bosch, D., Visser, B., & Stiekema, W. J. (1995) · Transgenic Research · doi:10.1007/bf01969415 · Cited by 101

Studies on the Mode of Action of the Antifungal Hexapeptide PAF26

Muñoz, A., López‐García, B., & Marcos, J. F. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00650-06 · Cited by 96

Inhibition of Fungal and Bacterial Plant Pathogens by Synthetic Peptides: In Vitro Growth Inhibition, Interaction Between Peptides and Inhibition of Disease Progression

Ali, G. S., & Reddy, A. S. N. (2000) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2000.13.8.847 · Cited by 95

Synthetic Antimicrobial Peptide Design

Powell, W. A. (1995) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi-8-0792 · Cited by 95

Biodiversity of apidaecin-type peptide antibiotics. Prospects of manipulating the antibacterial spectrum and combating acquired resistance

Casteels, P., Romagnolo, J., Castle, M., Casteels-Josson, K., Erdjument‐Bromage, H., & Tempst, P. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47165-7 · Cited by 93

Pathogen-induced expression of a cecropin A-melittin antimicrobial peptide gene confers antifungal resistance in transgenic tobacco

Yevtushenko, D. P., Romero, R., Forward, B. S., Hancock, R. E. W., Kay, W. W., & Misra, S. (2005) · Journal of Experimental Botany · doi:10.1093/jxb/eri165 · Cited by 92

Role of chitin synthase genes in Fusarium oxysporum

Martin-Udiroz, M. (2004) · Microbiology · doi:10.1099/mic.0.27236-0 · Cited by 88

Congeners of SMAP29 Kill Ovine Pathogens and Induce Ultrastructural Damage in Bacterial Cells

Kalfa, V. C., Jia, H. P., Kunkle, R. A., McCray, P. B., Tack, B. F., & Brogden, K. A. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.11.3256-3261.2001 · Cited by 86

Bacterial disease resistance of transgenic hybrid poplar expressing the synthetic antimicrobial peptide D4E1

Mentag, R., Luckevich, M. D., Morency, M., & Séguin, A. (2003) · Tree Physiology · doi:10.1093/treephys/23.6.405 · Cited by 83

Activity of the Antifungal Protein from Aspergillus giganteus Against Botrytis cinerea

Moreno, A. B., Martínez‐del‐Pozo, Á., Borja, M., & Segundo, B. S. (2003) · Phytopathology · doi:10.1094/phyto.2003.93.11.1344 · Cited by 82

Peptide-mediated broad-spectrum plant resistance to tospoviruses

Rudolph, C., Schreier, P. H., & Uhrig, J. F. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0730832100 · Cited by 81

Evaluation of Transgenic ‘Chardonnay’ (Vitis vinifera) Containing Magainin Genes for Resistance to Crown Gall and Powdery Mildew

Vidal, J. R., Kikkert, J. R., Malnoy, M., Wallace, P. G., Barnard, J. A., & Reisch, B. I. (2006) · Transgenic Research · doi:10.1007/s11248-005-4423-5 · Cited by 80

Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1

Zhu, W. L., Lan, H., Park, I., Kim, J. I., Jin, H. Z., Hahm, K., & Shin, S. Y. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.08.094 · Cited by 79

Expression of an Antifungal Peptide in Saccharomyces: A New Approach for Biological Control of the Postharvest Disease Caused by Colletotrichum coccodes

Jones, R. W., & Prusky, D. (2002) · Phytopathology® · doi:10.1094/phyto.2002.92.1.33 · Cited by 79

Sensitivity of Bacterial and Fungal Plant Pathogens to the Lytic Peptides, MSI-99, Magainin II, and Cecropin B

Alan, A. R., & Earle, E. D. (2002) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2002.15.7.701 · Cited by 78

The Medicinal Chemistry of Short Lactoferricin-Based Antibacterial Peptides

Haug, B. E., Strøm, M. B., & Svendsen, J. S. M. (2006) · Current Medicinal Chemistry · doi:10.2174/092986707779313435 · Cited by 78

Mutants of Ralstonia (Pseudomonas) solanacearum sensitive to antimicrobial peptides are altered in their lipopolysaccharide structure and are avirulent in tobacco

Titarenko, E., López‐Solanilla, E., García‐Olmedo, F., & Rodríguez‐Palenzuela, P. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.21.6699-6704.1997 · Cited by 77

Genetic modification of potato against microbial diseases: in vitro and in planta activity of a dermaseptin B1 derivative, MsrA2

Osusky, M., Osuska, L., Kay, W. W., & Misra, S. (2005) · Theoretical and Applied Genetics · doi:10.1007/s00122-005-2056-y · Cited by 76

Identification and Characterization of a Hexapeptide with Activity Against Phytopathogenic Fungi That Cause Postharvest Decay in Fruits

López‐García, B., González-Candelas, L., Pérez‐Payá, E., & Marcos, J. F. (2000) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2000.13.8.837 · Cited by 76

Design of Host Defence Peptides for Antimicrobial and Immunity Enhancing Activities

McPhee, J. B., Scott, M. G., & Hancock, R. E. W. (2005) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207053764558 · Cited by 75

Induced Expression of Sarcotoxin IA Enhanced Host Resistance Against Both Bacterial and Fungal Pathogens in Transgenic Tobacco

Mitsuhara, I., Matsufuru, H., Ohshima, M., Kaku, H., Nakajima, Y., Murai, N., Natori, S., & Ohashi, Y. (2000) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2000.13.8.860 · Cited by 73

Increasing bacterial disease resistance in plants utilizing antibacterial genes from insects

Jaynes, J. M., Xanthopoulos, K. G., Destéfano‐Beltrán, L., & Dodds, J. H. (1987) · BioEssays · doi:10.1002/bies.950060605 · Cited by 72

A Single Amino Acid Substitution in the Antimicrobial Defense Protein Cecropin B Is Associated with Diminished Degradation by Leaf Intercellular Fluid

Owens, L. D., & Heutte, T. M. (1997) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.1997.10.4.525 · Cited by 71

Biotechnologically relevant enzymes and proteins

Moreno, A. B., Martínez‐del‐Pozo, Á., & Segundo, B. S. (2006) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0362-1 · Cited by 71

Comparison of the activity of antifungal hexapeptides and the fungicides thiabendazole and imazalil against postharvest fungal pathogens

López‐García, B., Veyrat, A., Pérez-Payá, E., González-Candelas, L., & Marcos, J. F. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(03)00118-1 · Cited by 70

In vitro inhibition of postharvest pathogens of fruit and control of gray mold of strawberry and green mold of citrus by aureobasidin A

Liu, X., Wang, J., Ping, G., Mao, C., Zhu, Z., & Li, H. (2007) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2007.07.054 · Cited by 69

Amino acid sequence and disulfide bridges of an antifungal protein isolated from Aspergillus giganteus

Nakaya, K., Omata, K., Okahashi, I., Nakamura, Y., Kolkenbrock, H., & ULBRICH, N. (1990) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1990.tb19300.x · Cited by 68

Broad-Spectrum Antimicrobial Activity in vitro of the Synthetic Peptide D4E1

Rajasekaran, K., Stromberg, K. D., Cary, J. W., & Cleveland, T. E. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010154d · Cited by 66

Surface-Active Fungicidal d -Peptide Inhibitors of the Plasma Membrane Proton Pump That Block Azole Resistance

Monk, B. C., Niimi, K., Lin, S. X., Knight, A., Kardos, T. B., Cannon, R. D., Parshot, R., King, A., Lun, D. J., & Harding, D. R. K. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.1.57-70.2005 · Cited by 66

Improvement of cyclic decapeptides against plant pathogenic bacteria using a combinatorial chemistry approach

Monroc, S., Badosa, E., Besalú, E., Planas, M., Bardajı́, E., Montesinos, E., & Feliu, L. (2006) · Peptides · doi:10.1016/j.peptides.2006.05.001 · Cited by 64

Expression of the cationic antimicrobial peptide lactoferricin fused with the anionic peptide in Escherichia coli

Kim, H.-K., Chun, D.-S., Kim, J.-S., Yun, C.-H., Lee, J.-H., Hong, S., & Kang, D. (2006) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-005-0266-5 · Cited by 62

De novo designed cyclic cationic peptides as inhibitors of plant pathogenic bacteria

Monroc, S., Badosa, E., Feliu, L., Planas, M., Montesinos, E., & Bardajı́, E. (2006) · Peptides · doi:10.1016/j.peptides.2006.04.019 · Cited by 62

Activity of cecropin SB37 against protoplasts from several plant species and their bacterial pathogens

Nordeen, R. O., Sinden, S. L., Jaynes, J. M., & Owens, L. D. (1992) · Plant Science · doi:10.1016/0168-9452(92)90012-b · Cited by 61

Biological activity of Tat (47–58) peptide on human pathogenic fungi

Jung, H. J., Park, Y., Hahm, K., & Lee, D. G. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.04.059 · Cited by 60

Synthetic peptides derived from the β2−β3 loop of Raphanus sativus antifungal protein 2 that mimic the active site

Schaaper, W. M. M., Posthuma, G. A., Meloen, R. H., Plasman, H. H., Sijtsma, L., van Amerongen, A., Fant, F., BORREMANS, F. A. M., Thevissen, K., & Broekaert, W. F. (2001) · Journal of Peptide Research · doi:10.1034/j.1399-3011.2001.00842.x · Cited by 60

Expression of a magainin-type antimicrobial peptide gene (MSI-99) in tomato enhances resistance to bacterial speck disease

Alan, A. R., Blowers, A. D., & Earle, E. D. (2004) · Plant Cell Reports · doi:10.1007/s00299-003-0702-x · Cited by 59

Activity and mode of action against fungal phytopathogens of bovine lactoferricin-derived peptides

Muñoz, A., & Marcos, J. F. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.03089.x · Cited by 59

Expression of Human Lactoferrin cDNA Confers Resistance to Ralstonia solanacearum in Transgenic Tobacco Plants

Zhang, Z., Coyne, D. P., Vidaver, A. K., & Mitra, A. (1998) · Phytopathology · doi:10.1094/phyto.1998.88.7.730 · Cited by 58

Inhibition of a plant virus infection by analogs of melittin.

Marcos, J. F., Beachy, R. N., Houghten, R. A., Blondelle, S. E., & Pérez‐Payá, E. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.26.12466 · Cited by 57

Peptide Aptamers That Bind to a Geminivirus Replication Protein Interfere with Viral Replication in Plant Cells

López-Ochoa, L., Ramírez-Prado, J. H., & Hanley-Bowdoin, L. K. (2006) · Journal of Virology · doi:10.1128/jvi.02698-05 · Cited by 57

Neuronal uptake of pesticides disrupts chemosensory cells of nematodes

Winter, M. D., McPherson, M. J., & Atkinson, H. J. (2002) · Parasitology · doi:10.1017/s0031182002002482 · Cited by 55

Synthetic Peptide Combinatorial Libraries: A Method for the Identification of Bioactive Peptides Against Phytopathogenic Fungi

Reed, J. D., Edwards, D. L., & Gonzalez, C. F. (1997) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.1997.10.5.537 · Cited by 55

Characterization of antimicrobial peptides against a US strain of the rice pathogen Rhizoctonia solani

Oard, S. V., Rush, M. C., & Oard, J. H. (2004) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2004.02291.x · Cited by 55

Rapid identification of compounds with enhanced antimicrobial activity by using conformationally defined combinatorial libraries

Blondelle, S. E., Takahashi, E., Houghten, R. A., & Pérez‐Payá, E. (1996) · Biochemical Journal · doi:10.1042/bj3130141 · Cited by 54

Fungicidal properties, sterol binding, and proteolytic resistance of the synthetic peptide D4E1

Lucca, A. J. D., Bland, J. M., Grimm, C. C., Jacks, T. J., Cary, J. W., Jaynes, J. M., Cleveland, T. E., & Walsh, T. J. (1998) · Canadian Journal of Microbiology · doi:10.1139/w98-032 · Cited by 54

Antimicrobial properties of derivatives of the cationic tryptophan-rich hexapeptide PAF26

Muñoz, A., López‐García, B., Pérez‐Payá, E., & Marcos, J. F. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.12.173 · Cited by 54

An amphibian antimicrobial peptide variant expressed in Nicotiana tabacum confers resistance to phytopathogens

Ponti, D., Mangoni, M. L., Mignogna, G., Simmaco, M., & Barra, D. (2003) · Biochemical Journal · doi:10.1042/bj20021444 · Cited by 53

The production of synthetic chemodisruptive peptides in planta disrupts the establishment of cyst nematodes

Liu, B., Hibbard, J. K., Urwin, P. E., & Atkinson, H. J. (2005) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2005.00139.x · Cited by 52

Enhanced resistance to bacterial infection byErwinia carotovora subsp.atroseptica in transgenic potato plants expressing the attacin or the cecropin SB-37 genes

Arce‐Johnson, P., Moreno, M., Gutierrez, M., Gebauer, M., Dell’Orto, P., Torres, H., Acuña, I., Oliger, P., Venegas, A., Jordana, X., et al. (1999) · American Journal of Potato Research · doi:10.1007/bf02853582 · Cited by 51

The Antimicrobial Peptide Polyphemusin Localizes to the Cytoplasm of Escherichia coli following Treatment

Powers, J.-P. S., Martin, M. M., Goosney, D. L., & Hancock, R. E. W. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.4.1522-1524.2006 · Cited by 51

Erwinia soft rot resistance of potato cultivars expressing antimicrobial peptide tachyplesin I

Allefs, S. J. H. M., de Jong, E. R., Florack, D. E. A., Hoogendoorn, C., & Stiekema, W. J. (1996) · Molecular Breeding · doi:10.1007/bf00441425 · Cited by 50

Evidence for the breakdown of cecropin B by proteinases in the intercellular fluid of peach leaves

Mills, D., Hammerschlag, F. A., Nordeen, R. O., & Owens, L. D. (1994) · Plant Science · doi:10.1016/0168-9452(94)90186-4 · Cited by 50

Response of transgenic Royal Gala apple (Malus × domestica Borkh.) shoots carrying a modified cecropin MB39 gene, to Erwinia amylovora

Liu, Q., Ingersoll, J. C., Owens, L. D., Salih, S., Meng, R., & Hammerschlag, F. A. (2001) · Plant Cell Reports · doi:10.1007/s002990100333 · Cited by 50

Enhanced resistance to the poplar fungal pathogen, Septoria musiva, in hybrid poplar clones transformed with genes encoding antimicrobial peptides

Liang, H., Catranis, C. M., Maynard, C. A., & Powell, W. A. (2002) · Biotechnology Letters · doi:10.1023/a:1014552503140 · Cited by 48

Quest for antimicrobial genes to engineer disease-resistant crops

van der Biezen, E. A. (2001) · Trends in Plant Science · doi:10.1016/s1360-1385(01)01870-2 · Cited by 46

Partial Resistance to Bacterial Wilt in Transgenic Tomato Plants Expressing Antibacterial Lactoferrin Gene

Lee, T.-J., Coyne, D. P., Clemente, T. E., & Mitra, A. (2002) · Journal of the American Society for Horticultural Science · doi:10.21273/jashs.127.2.158 · Cited by 46

Comparison of pathogen‐induced expression and efficacy of two amphibian antimicrobial peptides, MsrA2 and temporin A, for engineering wide‐spectrum disease resistance in tobacco

Yevtushenko, D. P., & Misra, S. (2007) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2007.00277.x · Cited by 44

Structure and fungicidal activity of a synthetic antimicrobial peptide, P18, and its truncated peptides

Lee, D. G., Hahm, K., & Shin, S. Y. (2004) · Biotechnology Letters · doi:10.1023/b:bile.0000015472.09542.6d · Cited by 41

Effect of an antifungal peptide from oyster enzymatic hydrolysates for control of gray mold (Botrytis cinerea) on harvested strawberries

Liu, Z., Zeng, M., Dong, S., Xu, J., Song, H., & Zhao, Y. (2007) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2007.03.013 · Cited by 41

Role of the PhoP-PhoQ System in the Virulence of Erwinia chrysanthemi Strain 3937: Involvement in Sensitivity to Plant Antimicrobial Peptides, Survival at Acid pH, and Regulation of Pectolytic Enzymes

Llama‐Palacios, A., López‐Solanilla, E., & Rodríguez‐Palenzuela, P. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.6.2157-2162.2005 · Cited by 41

Comparative Study of Antimicrobial Peptides To Control Citrus Postharvest Decay Caused by Penicillium digitatum

Muñoz, A., López‐García, B., & Marcos, J. F. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0718143 · Cited by 39

Recombinant expression of indolicidin concatamers in Escherichia coli

Morin, K. M., Arcidiacono, S. M., Beckwitt, R., & Mello, C. M. (2005) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-005-0132-5 · Cited by 37

Formation and Characterization of a Single Trp-Trp Cross-link in Indolicidin That Confers Protease Stability without Altering Antimicrobial Activity

Ősapay, K., Tran, D., Ladokhin, A. S., White, S. H., Henschen, A., & Selsted, M. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.16.12017 · Cited by 37

Structural Dissection of a Highly Knotted Peptide Reveals Minimal Motif with Antimicrobial Activity

Vila‐Perelló, M., Sánchez‐Vallet, A., García‐Olmedo, F., Molina, A., & Andreu, D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410577200 · Cited by 36

Phage-Displayed Peptides as Developmental Agonists for Phytophthora capsici Zoospores

Bishop‐Hurley, S. L., Mounter, S. A., Laskey, J. G., Morris, R. O., Elder, J., Roop, P., Rouse, C., Schmidt, F. J., & English, J. T. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.7.3315-3320.2002 · Cited by 35

Improving on Natures Defenses: Optimization & High Throughput Screening of Antimicrobial Peptides

Raventós, D., Taboureau, O., Mygind, P. H., Nielsen, J., Sönksen, C. P., & Kristensen, H. H. (2005) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207053764549 · Cited by 35

Banana (Musa sp.)

Pérez, J. B., Remy, S., Swennen, R. L., & Sági, L. (2006) · Humana Press eBooks · doi:10.1385/1-59745-131-2:167 · Cited by 33

Construction of a novel synergistic system for production and recovery of secreted recombinant proteins by the cell surface engineering

Shibasaki, S., Kawabata, A., Ishii, J., Yagi, S., Kadonosono, T., Kato, M., 福田, 展., Kondo, A., & Ueda, M. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-007-0868-1 · Cited by 33

In vitro activities of antibiotics and antimicrobial peptides against the plant pathogenic bacterium Xylella fastidiosa

Kuzina, L. V., Miller, T. A., & Cooksey, D. A. (2006) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2006.01898.x · Cited by 32

Neutral glycolipids of the filamentous fungus Neurospora crassa:altered expression in plant defensin-resistant mutants

Park, C., Bennion, B., François, I., Ferket, K. K. A., Cammue, B. P. A., Thevissen, K., & Levery, S. B. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400457-jlr200 · Cited by 30

Increased pathogen resistance and yield in transgenic plants expressing combinations of the modified antimicrobial peptides based on indolicidin and magainin

Xing, H., Lawrence, C. B., Chambers, O. D., Davies, H. M., Everett, N. P., & Li, Q. Q. (2005) · Planta · doi:10.1007/s00425-005-0143-6 · Cited by 30

Antiviral indolicidin variant peptides: Evaluation for broad-spectrum disease resistance in transgenic Nicotiana tabacum

Bhargava, A., Osusky, M., Hancock, R. E. W., Forward, B. S., Kay, W. W., & Misra, S. (2006) · Plant Science · doi:10.1016/j.plantsci.2006.10.016 · Cited by 29

In vitro toxicity of natural and designed peptides to tree pathogens and pollen

Jacobi, V., Plourde, A., Charest, P. J., & Hamelin, R. C. (2000) · Canadian Journal of Botany · doi:10.1139/cjb-78-4-455 · Cited by 28

Constitutive expression of human lactoferrin and its N-lobe in rice plants to confer disease resistance

Takase, K., Hagiwara, K., Onodera, H., Nishizawa, Y., Ugaki, M., Omura, T., Numata, S., Akutsu, K., Kumura, H., & Shimazaki, K. (2005) · Biochemistry and Cell Biology · doi:10.1139/o05-022 · Cited by 27

Independent and Synergistic Activity of Synthetic Peptides Against Thiabendazole-Resistant Fusarium sambucinum

Gonzalez, C. F., Provin, E. M., Zhu, L., & Ebbole, D. J. (2002) · Phytopathology · doi:10.1094/phyto.2002.92.8.917 · Cited by 27

Antibacterial Activity of Synthetic Peptides Against Plant Pathogenic Pectobacterium Species

Kamysz, W., Królicka, A., Bogucka, K., Ossowski, T., Łukasiak, J., & Łojkowska, E. (2005) · Journal of Phytopathology · doi:10.1111/j.1439-0434.2005.00976.x · Cited by 26

Combinatorially selected defense peptides protect plant roots from pathogen infection

Fang, Z., Laskey, J. G., Huang, S., Bilyeu, K., Morris, R. O., Schmidt, F. J., & English, J. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605542103 · Cited by 25

A Minimalist Design Approach to Antimicrobial Agents Based on a Thionin Template

Vila‐Perelló, M., Tognon, S., Sánchez‐Vallet, A., García‐Olmedo, F., Molina, A., & Andreu, D. (2005) · Journal of Medicinal Chemistry · doi:10.1021/jm050882i · Cited by 25

An integrated analysis of the effects of Esculentin 1–21 on Saccharomyces cerevisiae

Gamberi, T., Cavalieri, D., Magherini, F., Mangoni, M. L., Filippo, C. D., Borro, M., Gentile, G., Simmaco, M., & Modesti, A. (2007) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2007.04.006 · Cited by 23

Release of aqueous contents from phospholipid vesicles induced by cecropin A (1–8)‐magainin 2 (1–12) hybrid and its analogues

Kang, J. H., Shin, S. Y., Jang, S. Y., Lee, M. K., & Hahm, K. S. (1998) · Journal of Peptide Research · doi:10.1111/j.1399-3011.1998.tb00651.x · Cited by 22

Transgenic Paulownia Expressing shiva‐1 Gene Has Increased Resistance to Paulownia Witches' Broom Disease

Tao, D. U., Yao, W. A. N. G., Qin‐Xue, H. U., Chen, J., Liu, S., HUANG, W., & Mulan, L. (2005) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2005.00168.x · Cited by 22

Plant defense gene promoter enhances the reliability of shiva-1 gene-induced resistance to soft rot disease in potato

Yi, J.-Y., Seo, H. W., Yang, M., Robb, E. J., Nazar, R. N., & Lee, S. W. (2004) · Planta · doi:10.1007/s00425-004-1346-y · Cited by 22

Magainin 2 effects on the ultrastructure of five plant pathogens

Kristyanne, E. S., Kim, K. S., & Stewart, J. M. (1997) · Mycologia · doi:10.1080/00275514.1997.12026794 · Cited by 22

Expression of an Antimicrobial Peptide via the Chloroplast Genome to Control Phytopathogenic Bacteria and Fungi

DeGray, G. (2001) · PLANT PHYSIOLOGY · doi:10.1104/pp.127.3.852 · Cited by 22

In silicoanalysis of antifungal peptides

Soltani, S., Keymanesh, K., & Sardari, S. (2007) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2.6.837 · Cited by 17

A tridecapeptide possesses both antimicrobial and protease-inhibitory activities

Li, Q. Q., Lawrence, C. B., Davies, H. M., & Everett, N. P. (2002) · Peptides · doi:10.1016/s0196-9781(01)00572-1 · Cited by 17

Expression of a polyphemusin variant in transgenic tobacco confers resistance against plant pathogenic bacteria, fungi and a virus

Bhargava, A., Osusky, M., Forward, B. S., Hancock, R. E. W., Kay, W. W., & Misra, S. (2007) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-007-9204-9 · Cited by 17

Structural changes of spores of tree fungal pathogens after treatment with the designed antimicrobial peptide D2A21

Rioux, D., Jacobi, V., Simard, M., & Hamelin, R. C. (2000) · Canadian Journal of Botany · doi:10.1139/b00-007 · Cited by 16

Transgenic Paulownia Expressing shiva-1 Gene Has Increased Resistance to Paulownia Witches＇ Broom Disease

Tao, T., Du, YAO, Y., Wang, Qin-Xue, Hu, Jie, J., Chen, C., Sheng, S., Liu, et al. (2005) · Journal of Integrative Plant Biology · Cited by 16

Magainin 2 Effects on the Ultrastructure of Five Plant Pathogens

Kristyanne, E. S., Kim, K. S., & Stewart, J. M. (1997) · Mycologia · doi:10.2307/3761029 · Cited by 16

The Interaction of Endochitinase, A Synthetic Peptide and Resveratrol in Controlling Fungi in vitro

Ali, G. S., Harman, G. E., & Reisch, B. I. (2003) · European Journal of Plant Pathology · doi:10.1023/a:1024797132744 · Cited by 15

Prosystemin-antimicrobial-peptide fusion reduces tomato late blight lesion expansion

Jones, R. W., Ospina-Giraldo, M. D., & Clemente, T. E. (2004) · Molecular Breeding · doi:10.1023/b:molb.0000038001.22029.07 · Cited by 15

Synthetic Combinatorial Libraries as an Alternative Strategy for the Development of Novel Treatments for Infectious Diseases

Blondelle, S. E., Pinilla, C., & Boggiano, C. (2003) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(03)69018-x · Cited by 14

Prospects for Combinatorial Chemistry in the Agrosciences

Lindell, S. D., & Scherkenbeck, J. (2005) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/138620705774575319 · Cited by 14

Modification of a Synthetic Antimicrobial Peptide (ESF1) for Improved Inhibitory Activity

Dykes, G. A., Aimoto, S., & Hastings, J. W. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.8940 · Cited by 13

Application of the “Codon-shuffling” Method

Rao, A., Chopra, S., Ram, G., Gupta, A., & Ranganathan, A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503056200 · Cited by 13

Sinorhizobium melilotigenes involved in tolerance to the antimicrobial peptide protamine

Nogales, J., Muñoz, S., Olivares, J., & Sanjuán, J. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00445.x · Cited by 11

Identification of Cecropin A Proteolytic Cleavage Sites Resulting from Aspergillus flavus Extracellular Protease(s)

Bland, J. M., & Lucca, A. J. D. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf980638i · Cited by 8

Design and screening of in vivo expressed antimicrobial peptide library

Choi, K.-C., Kim, H., Park, Y., Park, S.-M., & Kim, J. (2002) · Biotechnology Letters · doi:10.1023/a:1014076426705 · Cited by 5

Structural changes of spores of tree fungal pathogens after treatment with the designed antimicrobial peptide D2A21

Rioux, D., Jacobi, V., Simard, M., et al. (2000) · Canadian Journal of Botany · doi:10.1139/cjb-78-4-462 · Cited by 5

Biofuels from algae: Challenges and potential

Hannon, M., Gimpel, J., Tran, M., Rasala, B., & Mayfield, S. (2010) · Biofuels · doi:10.4155/bfs.10.44 · Cited by 813

GRAS, plant- and animal-derived compounds as alternatives to conventional fungicides for the control of postharvest diseases of fresh horticultural produce

Palou, L., Ali, A., Fallik, E., & Romanazzi, G. (2016) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2016.04.017 · Cited by 286

Antimicrobial peptides and bacteriocins: alternatives to traditional antibiotics

Sang, Y., & Blecha, F. (2008) · Animal Health Research Reviews · doi:10.1017/s1466252308001497 · Cited by 260

Protease Inhibitors from Plants with Antimicrobial Activity

Kim, J. Y., Park, S., Hwang, I., Cheong, H., Nah, J., Hahm, K., & Park, Y. (2009) · International Journal of Molecular Sciences · doi:10.3390/ijms10062860 · Cited by 243

Biotechnological advances for combating Aspergillus flavus and aflatoxin contamination in crops

Bhatnagar‐Mathur, P., Sunkara, S., Bhatnagar-Panwar, M., Waliyar, F., & Sharma, K. K. (2015) · Plant Science · doi:10.1016/j.plantsci.2015.02.009 · Cited by 200

Identification and rational design of novel antimicrobial peptides for plant protection, Annu

Muñoz, A., Pérez-payá, E., Investigación, C., Felipe, P., Profile, S., Misra, S., López‐García, B., Profile, S., Protection, P. F. P., Marcos, J. F., et al. (2016)

De-Novo Design of Antimicrobial Peptides for Plant Protection

Zeitler, B., Díaz, A. H., Dangel, A., Thellmann, M., Meyer, H., Sattler, M., & Lindermayr, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071687 · Cited by 66

Design of Antifungal Peptides for Agricultural Applications

Everett, N. P. (1993) · ACS symposium series · doi:10.1021/bk-1994-0551.ch020 · Cited by 17

De Novo Design of Antimicrobial Peptides With a Special Charge Pattern and Their Application in Combating Plant Pathogens

Chen, E. H. L., Weng, C., Li, Y., Wu, M.-C., Yang, C., Lee, K., Chen, R. P. ‐., & Cheng, C. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.753217 · Cited by 18

Harnessing Plant Antimicrobial Peptides for Crop Protection: From Molecular Defence Mechanisms to Peptide Engineering and Field Applications

Nwankwo, C. T., Alhaji, A. I., Abdulsalami, M. S., Haroun, A. A., Egbe, N. E., Oyong, A. I., & Okorie, J. M. (2026) · doi:10.9734/ajbge/2026/v9i2191