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Cited by 264

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Noninvasive Coronary Angiography with 16–Detector Row CT: Effect of Heart Rate

Hoffmann, Martin H. K., Shi, Heshui, Manzke, Robert, Schmid, Florian T., De Vries, Leon, Grass, Michael, Brambs, Hans-Jürgen, Aschoff, Andrik J.·2005·Radiology

Abstract

PURPOSE: To evaluate the effect of heart rate on the quality of coronary angiograms obtained with 16-detector row computed tomography (CT) by using temporally enhanced three-dimensional (3D) approaches. MATERIALS AND METHODS: The local ethics committee approved the study, and informed consent was obtained from all patients. Fifty patients underwent coronary CT angiography (heart rate range, 45-103 beats per minute). Raw data from helical CT and electrocardiography (ECG) were saved in a combined data set. Retrospectively ECG-gated images were reconstructed at preselected phases (50% and 80%) of the cardiac cycle. A 3D voxel-based approach with cardiac phase weighting was used for reconstruction. Testing for correlation between heart rate, cardiac phase reconstruction window, and image quality was performed with Kruskal-Wallis analysis. Image quality (freedom from cardiac motion-related artifacts) was referenced against findings at conventional angiography in a secondary evaluation step. Regression analysis was performed to calculate heart rate thresholds for future beta-blocker application. RESULTS: A significant negative correlation was observed between heart rate and image quality (r = 0.80, P < .001). Motion artifact-free images were available for 44 (88%) patients and were achieved consistently at a heart rate of 80 or fewer beats per minute (n = 39). Best image quality was achieved at 75 or fewer beats per minute. Segmental analysis revealed that 97% of arterial segments (diameter > or = 1.5 mm according to conventional angiography) were assessable at 80 or fewer beats per minute. Premature ventricular contractions and rate-contained arrhythmia did not impede diagnostic assessment of the coronary arteries in 10 (83%) of the 12 patients affected. CONCLUSION: Motion-free coronary angiograms can be obtained consistently with 16-detector row CT scanners and adaptive multicyclic reconstruction algorithms in patients with heart rates of less than 80 beats per minute.

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Metadata

Authors
Hoffmann, M. H. K., Shi, H., Manzke, R., Schmid, F. T., De Vries, L., Grass, M., Brambs, H.-J., & Aschoff, A. J.
Venue
Radiology
Published
2005-01
Volume
234
Issue
1
Pages
86-97
ISSN
  • 0033-8419 (ISSN-L)
  • 1527-1315
OpenAlex
W2130519322
Cited by
264
References
16
FWCI
31.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Noninvasive Coronary Angiography with 16–Detector Row CT: Effect of Heart Rate. https://app.cochat.ai/papers/10.1148/radiol.2341031408
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Hoffmann, M. H. K., Shi, H., Manzke, R., Schmid, F. T., De Vries, L., Grass, M., Brambs, H.-J., & Aschoff, A. J. (2005). Noninvasive Coronary Angiography with 16–Detector Row CT: Effect of Heart Rate. Radiology. https://doi.org/10.1148/radiol.2341031408

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