Cited by 69Artificial Intelligence in Healthcare and EducationCardiac Imaging and DiagnosticsArtificial Intelligence in Healthcare

Use of AI in Cardiac CT and MRI: A Scientific Statement from the ESCR, EuSoMII, NASCI, SCCT, SCMR, SIIM, and RSNA

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Mastrodicasa, Domenico, van Assen, Marly, Huisman, Merel, Leiner, Tim, Williamson, Eric E., Nicol, Edward D., Allen, Bradley D., Saba, Luca +2 more·2025·Radiology

Abstract

Artificial intelligence (AI) offers promising solutions for many steps of the cardiac imaging workflow, from patient and test selection through image acquisition, reconstruction, and interpretation, extending to prognostication and reporting. Despite the development of many cardiac imaging AI algorithms, AI tools are at various stages of development and face challenges for clinical implementation. This scientific statement, endorsed by several societies in the field, provides an overview of the current landscape and challenges of AI applications in cardiac CT and MRI. Each section is organized into questions and statements that address key steps of the cardiac imaging workflow, including ethical, legal, and environmental sustainability considerations. A technology readiness level range of 1 to 9 summarizes the maturity level of AI tools and reflects the progression from preliminary research to clinical implementation. This document aims to bridge the gap between burgeoning research developments and limited clinical applications of AI tools in cardiac CT and MRI.

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  • Studies did not discuss workflow elements of confirming AI-CAC reports, acting on results, or monitoring and correcting drift across longitudinal model performance.

    “Studies did not discuss workflow elements of confirming AI-CAC reports, acting on results, or monitoring and correcting drift across longitudinal model performance, which is important to ensure that deployment leads to the intended outcomes and maintains robust performance over time.18”

    From Prognostication and clinical opportunities with AI for coronary artery calcium: a scoping review (2026) · cites this paper as [18]

    The Current Limitations and Potential Solutions section identifies a lack of longitudinal monitoring strategies and says performance assessment is needed to maintain robust results over time. The Detection of Incidental Findings section calls for a plan to communicate coronary calcium findings and management recommendations. Neither passage establishes that studies failed to discuss confirming AI-CAC reports or acting on results. (LLM, conf=0.85)

    Experimental — accuracy not yet measured
  • The literature suggests that AI-CAC has reached advanced stages of technology readiness, reflecting substantial technical development and validation, but is still in relatively early stages of translational maturity with limited implementation and downstream clinical impact.

    “Overall, the literature suggests that AI-CAC has reached advanced stages of technology readiness,18 reflecting substantial technical development and validation, but is still in relatively early stages of translational maturity with limited implementation and downstream clinical impact.”

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Research works printed but not linked: 1

  1. Vaid A, Lampert J, Lee J, et al. Generative Large Language Models are autono- mous practitioners of evidence-based medicine. arXiv 2401.02851 [preprint] https://arxiv.org/abs/2401.02851. Posted January 5, 2024. Accessed February 7, 2024. · arXiv

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Authors
Mastrodicasa, D., van Assen, M., Huisman, M., Leiner, T., Williamson, E. E., Nicol, E. D., Allen, B. D., Saba, L., Vliegenthart, R., & Hanneman, K.
Affiliations
Mayo Clinic (US)
Corresponding author
  • Mastrodicasa, Domenico
  • Vliegenthart, Rozemarijn
  • Hanneman, Kate
Venue
Radiology
Published
2025-01-01
Volume
314
Issue
1
Pages
e240516-e240516
ISSN
  • 0033-8419 (ISSN-L)
  • 1527-1315
OpenAlex
W4406904445
Cited by
69
References
145
Citations by year
2026: 46 · 2025: 23
FWCI
4.08
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Radiology (publishedVersion, other-oa)
  • PubMed (publishedVersion)
  • PubMed Central (submittedVersion, other-oa)
  • Radboud Repository (Radboud University) (submittedVersion, other-oa)
  • UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
Funders
National Heart, Lung, and Blood Institute (R01HL168700)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
Keywords
artificial intelligence, cardiac CT, cardiac MRI, clinical implementation of AI, technology readiness level, image reconstruction, image interpretation, outcome prediction, legal and ethical considerations, environmental sustainability
MeSH terms
Artificial Intelligence, Heart, Heart Diseases, Humans, Magnetic Resonance Imaging, Societies, Medical, Tomography, X-Ray Computed, Cardiac Imaging Techniques

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