The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
Recent advances in thermoregulation
Open accessAbstract
Thermoregulation is the maintenance of a relatively constant core body temperature. Humans normally maintain a body temperature at 37°C, and maintenance of this relatively high temperature is critical to human survival. This concept is so important that control of thermoregulation is often the principal example cited when teaching physiological homeostasis. A basic understanding of the processes underpinning temperature regulation is necessary for all undergraduate students studying biology and biology-related disciplines, and a thorough understanding is necessary for those students in clinical training. Our aim in this review is to broadly present the thermoregulatory process taking into account current advances in this area. First, we summarize the basic concepts of thermoregulation and subsequently assess the physiological responses to heat and cold stress, including vasodilation and vasoconstriction, sweating, nonshivering thermogenesis, piloerection, shivering, and altered behavior. Current research is presented concerning the body's detection of thermal challenge, peripheral and central thermoregulatory control mechanisms, including brown adipose tissue in adult humans and temperature transduction by the relatively recently discovered transient receptor potential channels. Finally, we present an updated understanding of the neuroanatomic circuitry supporting thermoregulation.
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Cites
Textbook of Medical Physiology
(1966) · Annals of Internal Medicine · doi:10.7326/0003-4819-64-6-1363_2 · Cited by 9,749
The capsaicin receptor: a heat-activated ion channel in the pain pathway
Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., & Julius, D. (1997) · Nature · doi:10.1038/39807 · Cited by 9,107
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans
Saito, M., Okamatsu-Ogura, Y., Matsushita, M., Watanabe, K., Yoneshiro, T., Nio-Kobayashi, J., Iwanaga, T., Miyagawa, M., Kameya, T., Nakada, K., et al. (2009) · Diabetes · doi:10.2337/db09-0530 · Cited by 1,848
Unexpected evidence for active brown adipose tissue in adult humans
Nedergaard, J., Bengtsson, T., & Cannon, B. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00691.2006 · Cited by 1,824
A capsaicin-receptor homologue with a high threshold for noxious heat
Caterina, M. J., Rosen, T. A., Tominaga, M., Brake, A. J., & Julius, D. (1999) · Nature · doi:10.1038/18906 · Cited by 1,603
The menthol receptor TRPM8 is the principal detector of environmental cold
Bautista, D. M., Siemens, J., Glazer, J. M., Tsuruda, P. R., Basbaum, A. I., Stucky, C. L., Jordt, S.-E., & Julius, D. (2007) · Nature · doi:10.1038/nature05910 · Cited by 1,387
Influence of body temperature on the development of fatigue during prolonged exercise in the heat
González-Alonso, J., Teller, C., Andersen, S. L., Jensen, F. B., Hyldig, T., & Nielsen, B. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.86.3.1032 · Cited by 1,129
Skin blood flow in adult human thermoregulation: How it works, when it does not, and why
Charkoudian, N. (2003) · Mayo Clinic Proceedings · doi:10.4065/78.5.603 · Cited by 1,041
TRPV3 is a temperature-sensitive vanilloid receptor-like protein
Smith, G. D., Gunthorpe, M. J., Kelsell, R. E., Hayes, P. D., Reilly, P., Facer, P., Wright, J. E., Jerman, J. C., Walhin, J.-P., Ooi, L., et al. (2002) · Nature · doi:10.1038/nature00894 · Cited by 836
Adaptive thermogenesis in adipocytes: Is beige the new brown?
Wu, J., Cohen, P., & Spiegelman, B. M. (2013) · Genes & Development · doi:10.1101/gad.211649.112 · Cited by 828 · cited 1×
“There is some debate as to whether this tissue that behaves like BAT is actually true BAT or is so-called “beige adipose tissue,” which can develop from white fat cells in response to cold or 3-adrenergic agonists (77, 80).”
Cited by
Smart textiles for personalized thermoregulation
Fang, Y., Chen, G., Bick, M., & Chen, J. (2021) · Chemical Society Reviews · doi:10.1039/d1cs00003a · Cited by 423
A neuro-inspired artificial peripheral nervous system for scalable electronic skins
Lee, W. W., Tan, Y. J., Yao, H., Li, S., See, H. H., Hon, M., Ng, K. A., Xiong, B., Ho, J. S., & Tee, B. C. K. (2019) · Science Robotics · doi:10.1126/scirobotics.aax2198 · Cited by 318
Palmer, B., & DeLouise, L. (2016) · Molecules · doi:10.3390/molecules21121719 · Cited by 267
Temperature regulation in women: Effects of the menstrual cycle
Baker, F. C., Siboza, F., & Fuller, A. (2020) · Temperature · doi:10.1080/23328940.2020.1735927 · Cited by 262
Core Temperature Measurement—Principles of Correct Measurement, Problems, and Complications
Hymczak, H., Gołąb, A., Mendrala, K., Plicner, D., Darocha, T., Podsiadło, P., Hudziak, D., Gocoł, R., & Kosiński, S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182010606 · Cited by 161
Metadata
- Authors
- Tansey, E. A., & Johnson, C. D.
- Venue
- Advances in Physiology Education
- Publisher
- American Physiological Society
- Published
- 2015-09
- Volume
- 39
- Issue
- 3
- Pages
- 139-148
- ISSN
- 1043-4046 (ISSN-L)
- 1522-1229
- OpenAlex
- W2253106376
- Cited by
- 527
- References
- 80
- FWCI
- 11.62
- Type
- journal article
- Language
- en
- Open access
- green
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