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Cited by 236Hormonal and reproductive studiesLGBTQ Health, Identity, and PolicyBody Composition Measurement Techniques

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Effects of sex steroid hormones on regional fat depots as assessed by magnetic resonance imaging in transsexuals

Elbers, J. M. H., Asscheman, H., Seidell, J. C., Gooren, L. J. G.·1999·American Journal of Physiology-Endocrinology and Metabolism
DOI 10.1152/ajpendo.1999.276.2.e317
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Abstract

We investigated prospectively the effect of sex steroids on regional fat depots and thigh muscle mass in adult transsexuals. Ethinyl estradiol in combination with cyproterone acetate, a progestational antiandrogen, was given to 20 male-to-female (M-F) transsexuals, and parenteral testosterone esters were given to 17 female-to-male (F-M) transsexuals. Before and after 12 mo of cross-sex hormone administration, several anthropometric measurements (weight, skinfolds, body circumferences, and bioimpedance) were performed, and transverse magnetic resonance images were obtained at the level of the abdomen, hip, and thigh to quantify fat depots (subcutaneous and visceral) and muscle areas. We observed that treatment with ethinyl estradiol in M-F transsexuals induced a significant increase in all subcutaneous fat depots, with a lesser but proportional and significant increase in the visceral fat depot and a decrease in thigh muscle area. Testosterone administration in F-M transsexuals markedly increased thigh muscle area, reduced subcutaneous fat deposition at all levels measured, but slightly increased the visceral fat area. We conclude that sex steroid hormones are important determinants of the sex-specific localization of body fat.

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Crossref · 10.1152/ajpendo.1999.276.2.e317

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Research works printed but not linked: 15

  1. Arslanian S., 1997, J. Clin. Endocrinol. Metab., 82, 3213
  2. Baumgartner R. N., 1986, Hum. Biol., 58, 719
  3. Bhasin S., 1997, J. Clin. Endocrinol. Metab., 82, 407
  4. Björkelund C., 1996, Int. J. Obes., 20, 213
  5. Björntorp P., 1996, Int. J. Obes., 20, 291
  6. Elbers J. M. H., 1997, J. Clin. Endocrinol. Metab., 82, 2044
  7. Elbers J. M. H., 1997, J. Clin. Endocrinol. Metab., 82, 3267
  8. Espeland M. A., 1997, J. Clin. Endocrinol. Metab., 82, 1549
  9. Evans D. J., 1988, Int. J. Obes., 12, 157
  10. Lovejoy J. C., 1996, J. Clin. Endocrinol. Metab., 81, 2198
  11. Lovejoy J. C., 1995, Int. J. Obes., 19, 614
  12. Mårin P., 1992, Int. J. Obes., 16, 991
  13. Mårin P., 1993, Int. J. Obes., 17, 83
  14. Rebuffé-Scrive M., 1991, Int. J. Obes., 15, 791
  15. Van Kesteren P. J. M., 1996, J. Clin. Endocrinol. Metab., 81, 2227

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Metadata

Authors
Elbers, J. M. H., Asscheman, H., Seidell, J. C., & Gooren, L. J. G.
Affiliations
  • Vrije Universiteit Amsterdam (NL)
  • National Institute for Public Health and the Environment (NL)
ORCID
Venue
American Journal of Physiology-Endocrinology and Metabolism
Publisher
American Physiological Society
Published
1999-02-01
Volume
276
Issue
2
Pages
E317-E325
ISSN
  • 0193-1849 (ISSN-L)
  • 1522-1555
DOI
10.1152/ajpendo.1999.276.2.e317
OpenAlex
W2115643460
Cited by
236
References
45
Citations by year
2026: 4 · 2025: 14 · 2024: 5 · 2023: 9 · 2022: 10 · 2021: 17 · 2020: 11 · 2019: 9 · 2018: 15 · 2017: 10 · 2016: 6 · 2015: 12 · 2014: 11 · 2013: 15 · 2012: 11
FWCI
3.23
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Physiology-Endocrinology and Metabolism (publishedVersion)
  • PubMed (publishedVersion)
  • VU Research Portal (submittedVersion)
  • Rivm (National Institute for Public Health and the Environment) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
  • Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
Keywords
sex hormones, transsexuals, gender-affirming hormone therapy, ethinyl estradiol, cyproterone acetate, testosterone esters, subcutaneous adipose tissue, visceral fat, thigh muscle mass
MeSH terms
Adipose Tissue, Adolescent, Adult, Androgen Antagonists, Anthropometry, Drug Combinations, Ethinyl Estradiol, Female, Humans, Magnetic Resonance Imaging, Male, Prospective Studies, Sex Characteristics, Transsexualism, Cyproterone Acetate, Estradiol Congeners

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