The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Three-dimensional transmural organization of perimysial collagen in the heart
Open accessAbstract
There is strong support for the view that the ventricular myocardium has a laminar organization in which myocytes are grouped into branching layers separated by cleavage planes. However, understanding of the extent and functional implications of this architecture has been limited by the lack of a systematic three-dimensional description of the organization of myocytes and associated perimysial collagen. We imaged myocytes and collagen across the left ventricular wall at high resolution in seven normal rat hearts using extended volume confocal microscopy. We developed novel reconstruction and segmentation techniques necessary for the quantitative analysis of three-dimensional myocyte and perimysial collagen organization. The results confirm that perimysial collagen has an ordered arrangement and that it defines a laminar organization. Perimysial collagen is composed of three distinct forms: extensive meshwork on laminar surfaces, convoluted fibers connecting adjacent layers, and longitudinal cords. While myolaminae are the principal form of structural organization throughout most of the wall, they are not seen in the subepicardium, where perimysial collagen is present only as longitudinal cords.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In the native heart, overlapping myocardial fibers are arranged into distinct laminae four to six myocytes thick and separated from adjacent laminae by an extracellular collagen network42.”
From A tissue-engineered scale model of the heart ventricle (2018) · cites this paper as [42]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cardiac interstitium in health and disease: The fibrillar collagen network
Weber, K. T. (1989) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(89)90360-4 · Cited by 1,060
LeGrice, I. J., Smaill, B. H., Chai, L. Z., Edgar, S. G., Gavin, J. B., & Hunter, P. J. (1995) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1995.269.2.h571 · Cited by 841
Self-citationCollagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium.
Weber, K. T., Janicki, J. S., Shroff, S. G., Pick, R., Chen, R. M., & Bashey, R. I. (1988) · Circulation Research · doi:10.1161/01.res.62.4.757 · Cited by 556
Whittaker, P., Kloner, R. A., Boughner, D. R., & Pickering, J. G. (1994) · Basic Research in Cardiology · doi:10.1007/bf00788278 · Cited by 496
Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle.
Jalil, J., DOERING, C. W., Janicki, J. S., Pick, R., Shroff, S. G., & Weber, K. T. (1989) · Circulation Research · doi:10.1161/01.res.64.6.1041 · Cited by 491
(1979) · PubMed · Cited by 470
Shear properties of passive ventricular myocardium
Dokos, S., Smaill, B. H., Young, A. A., & LeGrice, I. J. (2002) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00111.2002 · Cited by 368
Self-citationCellular mechanisms of myocardial infarct expansion.
Weisman, H. F., Bush, D. E., Mannisi, J. A., Weisfeldt, M. L., & HEALY, B. P. (1988) · Circulation · doi:10.1161/01.cir.78.1.186 · Cited by 333
LeGrice, I. J., Takayama, Y., & Covell, J. W. (1995) · Circulation Research · doi:10.1161/01.res.77.1.182 · Cited by 316
Self-citationLaminar fiber architecture and three-dimensional systolic mechanics in canine ventricular myocardium
Costa, K. D., Takayama, Y., McCulloch, A. D., & Covell, J. W. (1999) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1999.276.2.h595 · Cited by 313
Cited by
Sorted by citations
Items 101–200 of 203
Schmid, H., Wang, Y., Ashton, J. L., Ehret, A. E., Krittian, S. B., Nash, M. P., & Hunter, P. J. (2008) · Computer Methods in Biomechanics & Biomedical Engineering · doi:10.1080/10255840802459420 · Cited by 17
A biophysical model for cardiac microimpedance measurements
Pollard, A. E., & Barr, R. C. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01131.2009 · Cited by 16
Studying the Microanatomy of the Heart in Three Dimensions: A Practical Update
Jarvis, J. C., & Stephenson, R. S. (2013) · Frontiers in Pediatrics · doi:10.3389/fped.2013.00026 · Cited by 16
Cardiac Tissue Engineering: From Matrix Design to the Engineering of Bionic Hearts
Fleischer, S., Feiner, R., & Dvir, T. (2017) · Regenerative Medicine · doi:10.2217/rme-2016-0150 · Cited by 18
A heart for fibrillin: spatial arrangement in adult wild-type murine myocardial tissue
Steijns, F., van Hengel, J., Sips, P. Y., Backer, J. F. A. D., & Renard, M. (2018) · Histochemistry and Cell Biology · doi:10.1007/s00418-018-1686-5 · Cited by 16
Microstructurally Motivated Constitutive Modeling of Heart Failure Mechanics
Hasaballa, A. I., Wang, V. Y., Sands, G. B., Wilson, A. J., Young, A. A., LeGrice, I. J., & Nash, M. P. (2019) · Biophysical Journal · doi:10.1016/j.bpj.2019.09.038 · Cited by 16
Self-citationImage-driven constitutive modeling of myocardial fibrosis
Wang, V. Y., Niestrawska, J. A., Wilson, A. J., Sands, G. B., Young, A. A., LeGrice, I. J., & Nash, M. P. (2016) · International Journal for Computational Methods in Engineering Science and Mechanics · doi:10.1080/15502287.2015.1082675 · Cited by 15
Self-citationMyocardial Fibrosis in a 3D Model: Effect of Texture on Wave Propagation
Dokuchaev, A., Panfilov, A. V., & Solovyova, O. E. (2020) · Mathematics · doi:10.3390/math8081352 · Cited by 15
Applying Harmonic Optical Microscopy for Spatial Alignment of Atrial Collagen Fibers
Chiu, Y. W., Lo, M. T., Tsai, M., Chang, Y.-C., Rb, H., Yu, H.-Y., Sun, C., & Ho, Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013917 · Cited by 15
On the structural origin of the anisotropy in the myocardium: Multiscale modeling and analysis
Tueni, N., Allain, J., & Genet, M. (2022) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2022.105600 · Cited by 14
Interstitial Collagen Loss, Myocardial Remodeling, and Function in Primary Mitral Regurgitation
Ahmed, M. I., Andrikopoulou, E., Zheng, J., Ulasova, E., Pat, B., Kelley, E. E., Powell, P. C., Denney, T. S., Lewis, C. T. P., Davies, J. E., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.04.014 · Cited by 14
Reconstruction of coronary circulation networks: A review of methods
Vigneshwaran, V., Sands, G. B., LeGrice, I. J., Smaill, B. H., & Smith, N. P. (2019) · Microcirculation · doi:10.1111/micc.12542 · Cited by 14
Self-citationIt's clearly the heart! Optical transparency, cardiac tissue imaging, and computer modelling
Sands, G. B., Ashton, J. L., Trew, M. L., Baddeley, D., Walton, R. D., Benoîst, D., Efimov, I. R., Smith, N. P., Bernus, O., & Smaill, B. H. (2021) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2021.06.005 · Cited by 14
Self-citationCardiac Magnetic Resonance Quantification of Structure-Function Relationships in Heart Failure
Nguyen, K., Hu, P., & Finn, J. P. (2020) · Heart Failure Clinics · doi:10.1016/j.hfc.2020.08.001 · Cited by 13
Juncos, J. X. M., Shakil, S., Bradley, W. E., Wei, C., Zafar, I., Powell, P. C., Mariappan, N., Louch, W. E., Ford, D. A., Ahmad, A. M., et al. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02919-8 · Cited by 12
Pearce, D., Nemcek, M. T., & Witzenburg, C. M. (2023) · Biophysical Reviews · doi:10.1007/s12551-023-01068-3 · Cited by 12
Gilbert, S., Sands, G. B., LeGrice, I. J., Smaill, B. H., Bernus, O., & Trew, M. L. (2012) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2012.6346859 · Cited by 12
Self-citationPalchesko, R. N., Sun, Y., Zhang, L., Szymanski, J. M., Jallerat, Q., & Feinberg, A. W. (2013) · Springer eBooks · doi:10.1007/978-3-642-20595-8_27 · Cited by 12
Dibb, R., & Liu, C. (2016) · Magnetic Resonance in Medicine · doi:10.1002/mrm.26321 · Cited by 12
Assessing Myocardial Architecture: The Challenges and Controversies
Agger, P., & Stephenson, R. S. (2020) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd7040047 · Cited by 11
Cardiomyopathy in Genetic Aortic Diseases
Mosquera, L. M., & Backer, J. F. A. D. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.682390 · Cited by 11
Wang, S., Varray, F., Liu, W., Clarysse, P., & Magnin, I. E. (2021) · Medical Image Analysis · doi:10.1016/j.media.2021.102269 · Cited by 11
Histological architecture of cardiac myofibers composing the left ventricle of murine heart
Gouda, Z. A., Elewa, Y. H. A., & Selim, A. O. (2015) · Journal of Histology and Histopathology · doi:10.7243/2055-091x-2-2 · Cited by 11
Magat, J., Fouillet, A., Constantin, M., Haliot, K., Naulin, J., Hamrani, D. E., Benoîst, D., Charron, S., Walton, R. D., Bernus, O., et al. (2021) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-020-00905-w · Cited by 10
Three-dimensional cardiac architecture determined by two-photon microtomy
Huang, H., MacGillivray, C., Kwon, H.-S., Lammerding, J., Robbins, J. M., Lee, R. T., & So, P. T. C. (2009) · Journal of Biomedical Optics · doi:10.1117/1.3200939 · Cited by 9
Fang, Y., Lu, B., Sun, R., Yang, P., Ye, Y., Ye, M., Zhang, Z., Yang, Y., Liu, Z., Xia, J., et al. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100306 · Cited by 8
Label‐free imaging of healthy and infarcted fetal sheep hearts by two‐photon microscopy
Sorvina, A., Bader, C. A., Lock, M. C., Brooks, D. A., Morrison, J. L., & Plush, S. E. (2017) · Journal of Biophotonics · doi:10.1002/jbio.201600296 · Cited by 8
Three-Dimensional Quantification of Myocardial Collagen Morphology from Confocal Images
Hasaballa, A. I., Sands, G. B., Wilson, A. J., Young, A. A., Wang, V. Y., LeGrice, I. J., & Nash, M. P. (2017) · Lecture notes in computer science · doi:10.1007/978-3-319-59448-4_1 · Cited by 8
Self-citationMyocardial Laminar Organization Is Retained in Angiotensin-Converting Enzyme Inhibitor Treated SHRs
Wilson, A. J., Sands, G. B., Wang, V. Y., Hasaballa, A. I., Pontré, B. P., Young, A. A., Nash, M. P., & LeGrice, I. J. (2020) · Experimental Mechanics · doi:10.1007/s11340-020-00622-4 · Cited by 8
Self-citationRoy, R., Warren, E., Xu, Y., Yow, C., Madhurapantula, R. S., Orgel, J. P. R. O., & Lister, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186503 · Cited by 8
Microarchitecture of the hearts in term and former‐preterm lambs using diffusion tensor imaging
Lê, B., Ferreira, P., Merchant, S. S., Zheng, G., Sutherland, M. R., Dahl, M. J., Albertine, K. H., & Black, M. J. (2020) · The Anatomical Record · doi:10.1002/ar.24516 · Cited by 8
Statistical analysis of transmural laminar microarchitecture of the human left ventricle
Mirea, I., Wang, L., Varray, F., Zhu, Y., Serrano, E. E. D., & Magnin, I. E. (2016) · International Conference on Signal Processing · doi:10.1109/icsp.2016.7877795 · Cited by 8
Lashgari, M., Ravikumar, N., Teh, I., Li, J., Buckley, D. L., Schneider, J. E., & Frangi, A. F. (2022) · Medical Image Analysis · doi:10.1016/j.media.2022.102592 · Cited by 7
Diffusion tensor cardiovascular magnetic resonance
Khalique, Z., & Pennell, D. J. (2019) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2019-136429 · Cited by 7
Multiphysics Computational Modelling of the Cardiac Ventricles
Bakir, A. A., Abed, A. A., Lovell, N. H., & Dokos, S. (2021) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2021.3093042 · Cited by 7
Anatomic considerations and examination of cardiovascular specimens (excluding devices)
Maleszewski, J. J., Lai, C. K., Nair, V., & Veinot, J. P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822224-9.00013-x · Cited by 7
Fish Heart Growth and Function: From Gross Morphology to Cell Signaling and Back
Tota, B., & Garofalo, F. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3387-3_3 · Cited by 7
Evaluation of left ventricular systolic function in young adults with mitral valve prolapse
Malev, E. G. (2014) · Europe PMC (PubMed Central) · doi:10.6084/m9.figshare.1104384 · Cited by 7
Faizan, A., Soe, S. P., Albon, J., Errington, R. J., & Theobald, P. S. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.09.044 · Cited by 6
Gilbert, S., Smaill, B. H., Walton, R. D., Trew, M. L., & Bernus, O. (2013) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6609596 · Cited by 6
Self-citationPreoperative left ventricular function in degenerative mitral valve disease
Malev, E. G., Kim, G., Mitrofanova, L. B., & Zemtsovsky, E. V. (2013) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e328362784f · Cited by 6
Left ventricular remodelling and diastolic dysfunction in mitral valve prolapse
Malev, E. G., Pshepiy, A., Васильевна, В. Л., Вениаминовна, Р. С., Timofeev, E. V., Korshunova, A., & Zemtsovsky, E. V. (2013) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2013-2-12-17 · Cited by 6
Oscillation of the orientation of cardiomyocyte aggregates in human left ventricle free wall
Wang, S., Cui, J., Jing, Y., & Varray, F. (2022) · Journal of Anatomy · doi:10.1111/joa.13795 · Cited by 6
Kienast, R., Handler, M. S., Stöger, M., Baumgarten, D., Hanser, F., & Baumgärtner, C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0182979 · Cited by 6
Self-preservation ability and residential fire emergencies.
MacEachron, A. E., & Janicki, M. P. (1983) · PubMed · Cited by 6
Malev, E. G., Борисовна, Л. Е., Вениаминовна, Р. С., Тимофеев, Е. В., Omelchenko, M. Y., & Zemtsovsky, E. V. (2021) · Progress in Pediatric Cardiology · doi:10.1016/j.ppedcard.2021.101347 · Cited by 5
Advancing Engineered Heart Muscle Tissue Complexity with Hydrogel Composites
Dickerson, D. A. (2022) · Advanced Biology · doi:10.1002/adbi.202200067 · Cited by 5
Schmid, H., Wang, W., Hunter, P. J., & Nash, M. P. (2009) · Computer Methods in Biomechanics & Biomedical Engineering · doi:10.1080/10255840902870427 · Cited by 5
Bioengineered Human Cardiac Ventricular Model with Transmural Helical Remodeling
Williams, N. P., Beussman, K. M., Foster, J. R., Rhodehamel, M., Williams, C. A., Tsui, J. H., Smith, A. S. T., Mengsteab, P. Y., Park, H., Mack, D. L., et al. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202502005 · Cited by 4
Osouli, K., Gaetano, F. D., Costantino, M. L., & Peirlinck, M. (2025) · Biomechanics and Modeling in Mechanobiology · doi:10.1007/s10237-025-01995-y · Cited by 4
Engineering the cardiac tissue microenvironment
Ronan, G., Bahcecioglu, G., Aliyev, N., & Zorlutuna, P. (2024) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/ad0ea7 · Cited by 4
A Mean-field Model of Ventricular Muscle Tissue
Hussan, J. R., Trew, M. L., & Hunter, P. J. (2012) · Journal of Biomechanical Engineering · doi:10.1115/1.4006850 · Cited by 4
Virtual Sources and Sinks During Extracellular Field Shocks in Cardiac Cell Cultures
Kondratyev, A. A., Didon, J.-P., Oberer, H., Lemay, M., Kučera, J., & Kléber, A. G. (2012) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.968180 · Cited by 4
Wang, S., Li, Z., Yuan, F., & Varray, F. (2023) · Journal of Morphology · doi:10.1002/jmor.21650 · Cited by 4
Wang, S., Varray, F., Yuan, F., & Magnin, I. E. (2021) · Lecture notes in computer science · doi:10.1007/978-3-030-78710-3_16 · Cited by 4
Dynamics of wave fronts and filaments in anisotropic cardiac tissuePreprint
Dierckx, H. (2015) · arXiv (Cornell University) · doi:10.48550/arxiv.1511.03685 · Cited by 4
Multiscale modeling of ventricular–vascular dysfunction in pulmonary arterial hypertension
Vélez‐Rendón, D., & Valdez‐Jasso, D. (2019) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2019.09.004 · Cited by 3
Nano‐ and Microstructured ECM and Biomimetic Scaffolds for Cardiac Tissue Engineering
Jallerat, Q., Szymanski, J. M., & Feinberg, A. W. (2014) · Wiley eBooks · doi:10.1002/9781118843499.ch12 · Cited by 3
Telle, Å., Maleckar, M. M., Wall, S., Powers, J. D., Augustin, C. M., Sundnes, J., & Boyle, P. M. (2025) · Journal of Biomechanical Engineering · doi:10.1115/1.4070346 · Cited by 2
Role of the Cardiac Sodium Current in Excitability and Conduction
Kléber, A. G. (2014) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2014.07.004 · Cited by 2
Analysis of Location-Dependent Cardiomyocyte Branching
Wilson, A. J., Sands, G. B., & Ennis, D. B. (2021) · Lecture notes in computer science · doi:10.1007/978-3-030-78710-3_19 · Cited by 2
Self-citationRelationship Between Structure and Mechanics for Membranous Tissues
Jor, J. W. Y., Gamage, T. P. B., Nielsen, P. M. F., Nash, M. P., & Hunter, P. J. (2016) · Springer eBooks · doi:10.1007/978-1-4899-7630-7_8 · Cited by 2
Lange, M., Hirahara, A. M., Ranjan, R., Stoddard, G. J., & Dosdall, D. J. (2021) · PLoS ONE · doi:10.1371/journal.pone.0258285 · Cited by 2
Intercellular Communication and Impulse Propagation
Kléber, A. G. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-2856-5.00027-3 · Cited by 2
Ventricular Helix Angle Trends and Long-Range Connectivity
Wilson, A. J., Han, Q., Perotti, L. E., & Ennis, D. B. (2023) · Lecture notes in computer science · doi:10.1007/978-3-031-35302-4_7 · Cited by 2
Second harmonic generation imaging of the collagen in myocardium for atrial fibrillation diagnosis
Tsai, M., Chiou, Y.-W., & Sun, C. (2009) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.809950 · Cited by 2
Kléber, A. G., & Janse, M. J. (2019) · Wiley eBooks · doi:10.1002/9781119152637.ch29 · Cited by 2
Williams, N. P., Beussman, K. M., Foster, J. R., Rhodehamel, M., Williams, C. A., Tsui, J. H., Smith, A. S. T., Mack, D. L., Murry, C. E., Sniadecki, N. J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.18.504345 · Cited by 2
Advanced electroactive nanofibrous patches for cardiac tissue regeneration: a comprehensive review
Doustvandi, B., Edrisi, F., Imani, R., & Yousefzadeh, M. (2026) · Biomedical Physics & Engineering Express · doi:10.1088/2057-1976/ae7803 · Cited by 1
Photoacoustic microscopy of myocardial sheet architecture in unfixed and unstained mammalian hearts
Zhang, C., Cheng, Y., Yao, D.-K., Wickline, S. A., & Wang, L. V. (2012) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.906208 · Cited by 1
de Lima, E. M. M., Santana, M. I. S., de Castro, M. B., Bombonato, P. P., Benedicto, H. G., & Vianna, A. R. D. C. B. (2011) · Ciência Rural · doi:10.1590/s0103-84782011000600018 · Cited by 1
Intelligent Surfaces for Cell and Tissue Delivery
Takahashi, H., & Okano, T. (2013) · Royal Society of Chemistry eBooks · doi:10.1039/9781849734318-00290 · Cited by 1
(2009) · The Internet Journal of Laboratory Medicine · doi:10.5580/10d9 · Cited by 1
Cell-to-Cell Communication and Impulse Propagation
Kléber, A. G. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-44733-1.00027-4 · Cited by 1
Submicron-resolution Photoacoustic Microscopy of Endogenous Light-absorbing Biomolecules
Zhang, C. (2014) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7jm27m4 · Cited by 1
Wang, Z., Wang, W., Liu, J., & Yang, J. Q. (2024) · Springer eBooks · doi:10.1007/978-981-19-7712-1_10 · Cited by 1
Myocardial Microstructure and Contractile Apparatus
Tarvala, U., & Khalique, Z. (2019) · Learning materials in biosciences · doi:10.1007/978-3-030-24219-0_4 · Cited by 1
Investigating Heart Failure Using Ventricular Imaging and Modelling
Wang, V. Y., Young, A. A., & Nash, M. P. (2010) · Lecture notes in computer science · doi:10.1007/978-3-642-15835-3_17 · Cited by 1
Dynamic Materials Mimic Developmental and Disease Changes in Tissues
Ondeck, M. G., & Engler, A. J. (2014) · Wiley eBooks · doi:10.1002/9781118843499.ch2
Strategies and Challenges for Bio‐inspired Cardiovascular Biomaterials
Lee, E. L., & Wong, J. Y. (2014) · Wiley eBooks · doi:10.1002/9781118843499.ch13
Multiscale topographical approaches for cell mechanobiology studies
Uto, K., Fisher, E., Kim, H. N., Seo, C. H., & Kim, D. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781139939751.006
Left ventricular function in mitral valve prolapse and severe mitral regurgitation
Malev, E. G., Kim, G. I., Mitrofanova, L. B., Omelchenko, M. Y., & Zemtsovsky, E. V. (2013) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2013-1-37-42
Towards reliable diffusion MRI of the in vivo human heart
Deuster, V., & von Deuster, C. (2016) · Research Portal (King's College London)
Directed cell alignment via extrusion-based 3D bioprinting for cardiac tissue engineering
Lee, J. M. (2018) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/75094
Quantitative descriptions of extended volume cardiac tissue architecture from multiple large hearts
Trew, M. L., Caldwell, B. J., & Smaill, B. H. (2018) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2018.8512309
Self-citationThe Role of Microscopic Tissue Structure in Defibrillation
Kléber, A. G., & Gillis, A. M. (2021) · Springer eBooks · doi:10.1007/978-3-030-63355-4_11
Faculty Opinions recommendation of A tissue-engineered scale model of the heart ventricle.
Radisic, M. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733680169.793554004
Faculty Opinions recommendation of A tissue-engineered scale model of the heart ventricle.
Truskey, G. A. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733680169.793549351
Flandes‐Iparraguirre, M. (2023) · Deposito Adademico Digital Universidad De Navarra (University of Navarra) · doi:10.15581/10171/69152
Yang, J., Xu, F., Jin, H., Zhou, Z., Wu, H., Zhang, W., Xue, M., Qiu, B., Gao, Q., Lin, B., et al. (2024) · Journal of Applied Polymer Science · doi:10.1002/app.56311
Pearce, D., Zheng, T., Campagnola, P. J., & Witzenburg, C. M. (2026) · Acta Biomaterialia · doi:10.1016/j.actbio.2026.07.003
Li, Z., Wang, S., Li, K., Gui, H., Yuan, F., Clarysse, P., & Varray, F. (2025) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2025.109058
Dell’Italia, L. J., Kane, M. S., Zheng, J., Huang, S.-W., Pat, B., & Denney, T. S. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.125.043558
Woven elastic interlayer for 3D‑printed hygroscopic tiles
Barnoin, J. A. H., Sabin, J. E., & Butcher, J. T. (2026) · Architectural Intelligence · doi:10.1007/s44223-025-00110-6
Faizan, A., Barnett, J. P., Bienemann, A., Janes, C.-A., & Theobald, P. S. (2026) · Annals of Biomedical Engineering · doi:10.1007/s10439-026-04143-4
Metadata
- Authors
- Pope, A. J., Sands, G. B., Smaill, B. H., & LeGrice, I. J.
- Affiliations
- University of Auckland (NZ)
- Venue
- American Journal of Physiology-Heart and Circulatory Physiology
- Publisher
- American Physiological Society
- Published
- 2008-09
- Volume
- 295
- Issue
- 3
- Pages
- H1243-H1252
- ISSN
- 0363-6135 (ISSN-L)
- 1522-1539
- PMC
- PMC2544485
- OpenAlex
- W2117433444
- Cited by
- 205
- References
- 51
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 4 · 2023: 8 · 2022: 9 · 2021: 16 · 2020: 16 · 2019: 14 · 2018: 12 · 2017: 10 · 2016: 11 · 2015: 15 · 2014: 12 · 2013: 15 · 2012: 18
- FWCI
- 7.55
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Physiology-Heart and Circulatory Physiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- ResearchSpace (University of Auckland) (submittedVersion)
- Funders
- National Heart Foundation of New Zealand
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiomyopathy and Myosin Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- left ventricular wall, 3D reconstruction, collagen fiber arrangement, subepicardium, rat heart
- MeSH terms
- Animals, Collagen, Endocardium, Heart Ventricles, Image Processing, Computer-Assisted, Male, Myocardium, Pericardium, Rats, Inbred WKY, Rats, Wistar, Microscopy, Confocal, Myocytes, Cardiac, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
