Cited by 197Chronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory Support and MechanismsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

The DOI matches its Crossref record.

Effect of aging alone on mechanical properties of the normal adult human lung

Knudson, R. J., Clark, D. F., Kennedy, T. C., Knudson, D. E.·1977·Journal of Applied Physiology

DOI 10.1152/jappl.1977.43.6.1054

Open this paper in CoChat — free account

Abstract

For plethysmographic studies of respiratory mechanics, we selected, from a general population, 51 subjects, aged 25-75 yr, who had never smoked, had no present or past cardiorespiratory symptoms or disease, were alpha1-antitrypsin MM phenotypes, and were normal by physical examination, vectorcardiography, and chest roentgenography. Approximately equal numbers of men and women were represented in each of three age groups; 25-35, 36-64, and 65-75. Both sexes demonstrated loss of lung elastic recoil with age, most significant at high lung volumes, but the rate of loss was less than previously reported. Males had higher lung recoil than females of comparable age, but if lung size was taken into account, there were no sex differences in bulk elastic properties. Maximum expiratory flow diminished with age only at low volumes, suggesting that equal pressure points are more centrally located at low lung volumes in the elderly.

Integrity signals

Registry

Crossref · 10.1152/jappl.1977.43.6.1054

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Still being checked.

Sorted by citations

Improvement in Pulmonary Function and Elastic Recoil after Lung-Reduction Surgery for Diffuse Emphysema
Sciurba, F. C., Rogers, R. M., Keenan, R. J., Slivka, W. A., Gorcsan, J., Ferson, P. F., Holbert, J. M., Brown, M. L., & Landreneau, R. J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199604253341704 · Cited by 461
Tissue elasticity and the ageing elastic fibre
Sherratt, M. J. (2009) · AGE · doi:10.1007/s11357-009-9103-6 · Cited by 342
Titration of Tidal Volume and Induced Hypercapnia in Acute Respiratory Distress Syndrome
Roupie, É., DAMBROSIO, M., Servillo, G., Mentec, H., Atrous, S. E., Beydon, L., Brun‐Buisson, C., Lemaire, F., & Brochard, L. J. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.152.1.7599810 · Cited by 321
Incidence of exercise-induced bronchospasm in Olympic winter sport athletes
Wilber, R. L., Rundell, K. W., SZMEDRA, L., JENKINSON, D. M., Im, J., & Drake, S. D. (2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200004000-00003 · Cited by 265
A simple method to detect expiratory flow limitation during spontaneous breathing
Koulouris, N. G., Valta, P., Lavoie, A., Corbeil, C., Chasse, M., Braidy, J., & Milic‐Emili, J. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08020306 · Cited by 249
Lung Mechanics in Disease
Pride, N. B., & Macklem, P. T. (1986) · Comprehensive physiology · doi:10.1002/cphy.cp030337 · Cited by 197
Risk Factors for Growth and Decline of Lung Function in Asthmatic Individuals up to Age 42 years: A 30-year Follow-up Study
GROL, M. H., Gerritsen, J., Vonk, J. M., Schouten, J. P., Koëter, G. H., Rijcken, B., & Postma, D. S. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.6.9812100 · Cited by 180
Neutrophils and low-grade inflammation in the seemingly normal aging human lung
Meyer, K. C., Rosenthal, N. S., Soergel, P., & Peterson, K. (1998) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(98)00065-7 · Cited by 179
Immune dysregulation in the aging human lung
Meyer, K. C., Ershler, W., Rosenthal, N. S., Lu, X. G., & Peterson, K. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.153.3.8630547 · Cited by 173
Mechanisms of airway hyper‐responsiveness in asthma: the past, present and yet to come
Chapman, D. G., & Irvin, C. G. (2015) · Clinical & Experimental Allergy · doi:10.1111/cea.12506 · Cited by 180
Effects of age on elastic moduli of human lungs
LAI-FOOK, S. J., & Hyatt, R. E. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.163 · Cited by 170
Increase in Pulmonary Ventilation–Perfusion Inequality with Age in Healthy Individuals
CARDÚS, J., BURGOS, F., DIAZ, O., ROCA, J., BARBERÁ, J. A., MARRADES, R. M., RODRIGUEZ-ROISIN, R., & WAGNER, P. D. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.2.9606016 · Cited by 165
State of the Art. A Structural and Functional Assessment of the Lung via Multidetector-Row Computed Tomography: Phenotyping Chronic Obstructive Pulmonary Disease
Hoffman, E. A., Simon, B. A., & McLennan, G. (2006) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200603-086ms · Cited by 159
The Aging Voice: A Review, Treatment Data and Familial and Genetic Perspectives
Ramig, L. O., Gray, S. G., Baker, K. K., Corbin-Lewis, K., Buder, E. H., Luschei, E. S., Coon, H., & Smith, M. E. (2001) · Folia Phoniatrica et Logopaedica · doi:10.1159/000052680 · Cited by 157
Effect of alveolar recruitment maneuver in early acute respiratory distress syndrome according to antiderecruitment strategy, etiological category of diffuse lung injury, and body position of the patient*
Lim, C., Jung, H., Koh, Y., Lee, J. S., Shim, T. S., Lee, S., Kim, W., Kim, D. S., & Kim, W. D. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000048631.88155.39 · Cited by 147
Improved pulmonary function in systemic sclerosis after treatment with cyclophosphamide
Åkesson, A., Scheja, A., Lundin, A., & Wollheim, F. A. (1994) · Arthritis & Rheumatism · doi:10.1002/art.1780370518 · Cited by 150
Expiratory Computed Tomography for Assessment of Suspected Pulmonary Emphysema
Knudson, R. J., Standen, J. R., Kaltenborn, W. T., Knudson, D. E., Rehm, K., Habib, M. P., & Newell, J. D. (1991) · CHEST Journal · doi:10.1378/chest.99.6.1357 · Cited by 149
Self-citation
Prediction equations for plethysmographic lung volumes
Roca, J., Burgos, F., Barberà, J. A., Sunyer, J., Rodriguez‐Roisin, R., Castellsagué, J., Sanchis, J., Antóo, J. M., Casán, P., & Clausen, J. L. (1998) · Respiratory Medicine · doi:10.1016/s0954-6111(98)90291-8 · Cited by 138
EFFECT OF AGING ON RESPIRATORY SKELETAL MUSCLES
Tolep, K. A., & Kelsen, S. G. (1993) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(21)00901-1 · Cited by 134
Aging and the respiratory system
Rossi, A., Ganassini, A., Tantucci, C., & Grassi, V. (1996) · Aging Clinical and Experimental Research · doi:10.1007/bf03339671 · Cited by 132
The Aging Lung and Chronic Obstructive Pulmonary Disease: Similarity and Difference
Fukuchi, Y. (2009) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200909-099rm · Cited by 126
A Descriptive Analysis of the Growth and Decline of the FVC and FEV1
Burrows, B. A., Cline, M. G., Knudson, R. J., Taussig, L. M., & Lehowitz, M. D. (1983) · CHEST Journal · doi:10.1378/chest.83.5.717 · Cited by 123
Self-citation
IMPACT OF THE AGING PULMONARY SYSTEM ON THE RESPONSE TO EXERCISE
Johnson, B. D., Badr, M. S., & Dempsey, J. A. (1994) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(21)01070-4 · Cited by 115
Normative aging of the respiratory system
Zeleznik, J. (2003) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(02)00063-0 · Cited by 108
Asthma and Chronic Obstructive Pulmonary Disease
Postma, D. S., Reddel, H. K., ten Hacken, N. H. T., & van den Berge, M. (2013) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2013.09.010 · Cited by 106
Pulmonary Gas Exchange and Acid‐Base Balance During Exercise
Stickland, M. K., Lindinger, M. I., Olfert, I. M., Heigenhauser, G. J. F., & Hopkins, S. R. (2013) · Comprehensive physiology · doi:10.1002/cphy.c110048 · Cited by 106
Effect of obesity on respiratory mechanics during rest and exercise in COPD
Ora, J., Laveneziana, P., Wadell, K., Preston, M., Webb, K. A., & O'Donnell, D. E. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01131.2010 · Cited by 101
Impaired Bronchodilator Response to Albuterol in Healthy Elderly Men and Women
Connolly, M. J., Crowley, J. J., Charan, N. B., Nielson, C., & Vestal, R. E. (1995) · CHEST Journal · doi:10.1378/chest.108.2.401 · Cited by 97
Inspiratory muscle force in normal subjects and patients with interstitial lung disease.
Troyer, A. D., & Yernault, J. C. (1980) · Thorax · doi:10.1136/thx.35.2.92 · Cited by 92
Special Problems in the Elderly
Oskvig, R. M. (1999) · CHEST Journal · doi:10.1378/chest.115.suppl_2.158s · Cited by 90
The Aging Respiratory System
Krumpe, P. E., Knudson, R. J., Parsons, G. H., & Reiser, K. M. (1985) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(18)30963-7 · Cited by 93
Self-citation
Respiratory Mechanics in Children
Bryan, A. C., & Wohl, M. E. B. (1986) · Comprehensive physiology · doi:10.1002/cphy.cp030312 · Cited by 77
Thoracic Dimensions at Maximum Lung Inflation in Normal Subjects and in Patients With Obstructive and Restrictive Lung Diseases
Bellemare, J.-F., Cordeau, M., Leblanc, P., & Bellemare, F. (2001) · CHEST Journal · doi:10.1378/chest.119.2.376 · Cited by 72
The Aging Lung
Mahler, D. A., Rosiello, R., & Loke, J. S. O. (1986) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(18)30878-4 · Cited by 72
Aging and the Respiratory System
Brandstetter, R. D., & Kazemi, H. (1983) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)31212-3 · Cited by 67
Effects of age on pulmonary perfusion heterogeneity measured by magnetic resonance imaging
Levin, D. L., Buxton, R. B., Spiess, J. P., Arai, T. J., Balouch, J., & Hopkins, S. R. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00512.2006 · Cited by 61
Spirometry After Transplantation: How Much Better Are Two Lungs Than One?
Mason, D. P., Rajeswaran, J., Murthy, S. C., McNeill, A. M., Budev, M. M., Mehta, A. C., Pettersson, G., & Blackstone, E. H. (2008) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2007.12.023 · Cited by 61
Aging effects on airflow dynamics and lung function in human bronchioles
Kim, J.-W., Heise, R. L., Reynolds, A., & Pidaparti, R. M. V. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183654 · Cited by 61
Mechanism of reduced maximal expiratory flow with aging
Babb, T. G., & Rodarte, J. R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.2.505 · Cited by 58
Predictors of Airway Hyperresponsiveness Differ Between Old and Young Patients With Asthma
Hardaker, K. M., Downie, S. R., Kermode, J. A., Farah, C. S., Brown, N. J., Berend, N., King, G. G., & Salome, C. M. (2011) · CHEST Journal · doi:10.1378/chest.10-1839 · Cited by 55
Speech Breathing in Senescent and Younger Women During Oral Reading
Sperry, E. E., & Klich, R. J. (1992) · Journal of Speech Language and Hearing Research · doi:10.1044/jshr.3506.1246 · Cited by 55
Sexual dimorphism of human ribs
Bellemare, F., Fuamba, T., & Bourgeault, A. (2005) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2005.04.002 · Cited by 54
Aging Adults and Seasonal Influenza: Does the Vitamin D Status (H)Arm the Body?
Lang, P. O., & Samaras, D. (2011) · Journal of Aging Research · doi:10.1155/2012/806198 · Cited by 53
Evaluation of lung elastic recoil by exponential curve analysis
Knudson, R. J., & Kaltenborn, W. T. (1981) · Respiration Physiology · doi:10.1016/0034-5687(81)90066-9 · Cited by 51
Self-citation
Post-mortem lung volumes.
Thurlbeck, W. M. (1979) · Thorax · doi:10.1136/thx.34.6.735 · Cited by 50
Respiratory Rate during Acute Asthma
Kesten, S., Maleki-Yazdi, M. R., Sanders, B. R., Wells, J. A., McKillop, S. L., Chapman, K. R., & Rebuck, A. S. (1990) · CHEST Journal · doi:10.1378/chest.97.1.58 · Cited by 48
Measurement of Pulmonary Density by Means of X-ray Computerized Tomography
Wollmer, P., Albrechtsson, U., Brauer, K., Eriksson, L. T., Jonson, B., & Tylén, U. (1986) · CHEST Journal · doi:10.1378/chest.90.3.387 · Cited by 48
Joint Indian Chest Society-National College of Chest Physicians (India) guidelines for spirometry
Aggarwal, A. N., Agarwal, R., Dhooria, S., Prasad, K. T., Sehgal, I. S., Muthu, V., Singh, N., Behera, D., Jindal, S. K., Singh, V., et al. (2019) · Lung India · doi:10.4103/lungindia.lungindia_300_18 · Cited by 46
Reduced lung elastic recoil and fixed airflow obstruction in asthma
Tonga, K. O., Chapman, D. G., Farah, C. S., Oliver, B. G. G., Zimmermann, S. C., Milne, S. B., Sanai, F., Jetmalani, K., Berend, N., Thamrin, C., et al. (2019) · Respirology · doi:10.1111/resp.13688 · Cited by 44
Anaesthesia for the geriatric dog and cat
Hughes, J. M. L. (2008) · Irish Veterinary Journal · doi:10.1186/2046-0481-61-6-380 · Cited by 45
Airspace Enlargement With Airway Cell Apoptosis in Klotho Mice: A Model of Aging Lung
Ishii, M., Yamaguchi, Y., Yamamoto, H., Hanaoka, Y., & Ouchi, Y. (2008) · The Journals of Gerontology Series A · doi:10.1093/gerona/63.12.1289 · Cited by 42
Demographics of health and disease in the geriatric horse
Paradis, M. R. (2002) · Veterinary Clinics of North America Equine Practice · doi:10.1016/s0749-0739(02)00021-4 · Cited by 41
Cardiovascular consequences of the inspiratory muscle metaboreflex: effects of age and sex
Smith, J. R., Alexander, A. M., Hammer, S. M., Didier, K. D., Kurti, S. P., Broxterman, R. M., Barstow, T. J., & Harms, C. A. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00818.2016 · Cited by 41
Tests of Mechanical Function
Anthonisen, N. R. (1986) · Comprehensive physiology · doi:10.1002/cphy.cp030344 · Cited by 40
Ventilatory constraints and dyspnea during exercise in chronic obstructive pulmonary disease
Laveneziana, P., Parker, C. M., & O’Donnell, D. E. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-119 · Cited by 39
Evaluation of the Normal Airway Morphology Using Optical Coherence Tomography
Su, Z., Guan, W., Li, S., Feng, J., Zhou, Z., Chen, Y., Zhong, M., & Zhong, N. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.06.009 · Cited by 38
Pharmacogeriatrics
Pucino, F., Beck, C. L., Seifert, R. L., Strommen, G. L., Sheldon, P. A., & Silbergleit, I. L. (1985) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/j.1875-9114.1985.tb03437.x · Cited by 38
Elastic recoil changes in early emphysema
Silvers, G. W., Petty, T. L., & Stanford, R. E. (1980) · Thorax · doi:10.1136/thx.35.7.490 · Cited by 37
Age and Sex Dependence of Forced Expiratory Central Airway Collapse in Healthy Volunteers
O’Donnell, C. R., Litmanovich, D. E., Loring, S. H., & Boiselle, P. M. (2011) · CHEST Journal · doi:10.1378/chest.11-2361 · Cited by 37
Peripheral mononuclear leucocyte beta adrenoceptors and non-specific bronchial responsiveness to methacholine in young and elderly normal subjects and asthmatic patients.
Connolly, M. J., Crowley, J. J., Nielson, C., Charan, N. B., & Vestal, R. E. (1994) · Thorax · doi:10.1136/thx.49.1.26 · Cited by 37
Facteurs influençant les variables ventilatoires des Tunisiennes âgées de 45 ans et plus
Saad, H. B., Tfifha, M., Harrabi, I., Tabka, Z., Guénard, H. J.-P., Hayot, M., & Zbidi, A. (2006) · Revue des Maladies Respiratoires · doi:10.1016/s0761-8425(06)71598-4 · Cited by 36
Resistive and elastic work of breathing in older and younger adults during exercise
Smith, J. R., Cross, T. J., Iterson, E. H. V., Johnson, B. D., & Olson, T. P. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01105.2017 · Cited by 35
Quantifying the shape of the maximal expiratory flow–volume curve in mild COPD
Dominelli, P. B., Foster, G. E., Guenette, J. A., Haverkamp, H. C., Eves, N. D., Dominelli, G. S., Henderson, W. R., O’Donnell, D. E., & Sheel, A. W. (2015) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2015.08.002 · Cited by 34
Effect of increased inspiratory muscle work on blood flow to inactive and active limbs during submaximal dynamic exercise
Katayama, K., Goto, K., Shimizu, K., Saito, M., Ishida, K., Zhang, L., Shiozawa, K., & Sheel, A. W. (2018) · Experimental Physiology · doi:10.1113/ep087380 · Cited by 34
An Analytical Model for Estimating Alveolar Wall Elastic Moduli From Lung Tissue Uniaxial Stress-Strain Curves
Jawde, S. B., Takahashi, A., Bates, J. H. T., & Suki, B. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00121 · Cited by 34
Effects of age and exercise on physiological dead space during simulated dives at 2.8 ATA
Mummery, H. J., Stolp, B. W., Dear, G. D. L., Doar, P. O., Natoli, M. J., Boso, A. E., Archibald, J. D., Hobbs, G. W., El-Moalem, H. E., & Moon, R. E. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00367.2002 · Cited by 34
Comparison of the functional results of single lung transplantation for pulmonary fibrosis and chronic airway obstruction
Chacon, R. A., Corris, P. A., Dark, J. H., & Gibson, G. J. (1998) · Thorax · doi:10.1136/thx.53.1.43 · Cited by 34
Assessment of alpha-1-antitrypsin deficiency heterozygosity as a risk factor in the etiology of emphysema. Physiological comparison of adult normal and heterozygous protease inhibitor phenotype subjects from a random population.
McDonagh, D. J., Nathan, S. P., Knudson, R. J., & Lebowitz, M. D. (1979) · Journal of Clinical Investigation · doi:10.1172/jci109303 · Cited by 33
Self-citation
Airway wall thickness on HRCT scans decreases with age and increases with smoking
Telenga, E. D., Oudkerk, M., van Ooijen, P. M. A., Vliegenthart, R., ten Hacken, N. H. T., Postma, D. S., & van den Berge, M. (2017) · BMC Pulmonary Medicine · doi:10.1186/s12890-017-0363-0 · Cited by 31
Neonatal pulmonary oxygen toxicity in the rat and lung changes with aging
Thibeault, D. W., Mabry, S. M., & Rezaiekhaligh, M. (1990) · Pediatric Pulmonology · doi:10.1002/ppul.1950090207 · Cited by 31
Expiratory flow limitation and operating lung volumes during exercise in older and younger adults
Smith, J. R., Kurti, S. P., Meskimen, K., & Harms, C. A. (2017) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2016.12.016 · Cited by 30
New physiological insights into dyspnea and exercise intolerance in chronic obstructive pulmonary disease patients
Laveneziana, P., Guenette, J. A., Webb, K. A., & O’Donnell, D. E. (2012) · Expert Review of Respiratory Medicine · doi:10.1586/ers.12.70 · Cited by 31
Biochemical characteristics of lungs in senescence-accelerated mouse (SAM)
Teramoto, S., Fukuchi, Y., Uejima, Y., Teramoto, K., & Orimo, H. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08030450 · Cited by 28
Original article: Long-term effects on pulmonary function of mantle radiotherapy in patients with Hodgkin’s disease
Gustavsson, A., ESKILSSON, J., Landberg, T. G., Larusdottir, H., Svahn‐Tapper, G., White, T., & Wollmer, P. (1992) · Annals of Oncology · doi:10.1093/oxfordjournals.annonc.a058234 · Cited by 28
[Age-related changes in static maximal inspiratory and expiratory pressures].
Suzuki, M., Teramoto, S., Sudo, E., Ogawa, K., Namekawa, T., Motrita, K., Matsuse, T., Takizawa, H., Ouchi, Y., & Fukuchi, Y. (1997) · PubMed · Cited by 27
Influences of inhaled tobacco smoke on the senescence accelerated mouse (SAM)
Uejima, Y., Fukuchi, Y., Nagase, T., Matsuse, T., Yamaoka, M., Tabata, R., & Orimo, H. (1990) · European Respiratory Journal · doi:10.1183/09031936.93.03091029 · Cited by 25
Age-related changes in the antioxidant screen of the distal lung in mice
Teramoto, S., Fukuchi, Y., Uejima, Y., Teramoto, K., Ito, H., & Orimo, H. (1994) · Lung · doi:10.1007/bf00164439 · Cited by 25
Subclinical Effects of Smoking
Knudson, R. J., Bloom, J. W., Knudson, D. E., & Kaltenborn, W. T. (1984) · CHEST Journal · doi:10.1378/chest.86.1.20 · Cited by 25
Self-citation
Speech Breathing Across the Life Span and in Disease
Huber, J. E., & Stathopoulos, E. T. (2015) · doi:10.1002/9781118584156.ch2 · Cited by 24
Does increased baseline ventilation heterogeneity following chest wall strapping predispose to airway hyperresponsiveness?
Chapman, D. G., Berend, N., Horlyck, K. R., King, G. G., & Salome, C. M. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01582.2011 · Cited by 23
A new murine model of aging lung: The senescence accelerated mouse (SAM)-P
Uejima, Y., Fukuchi, Y., Nagase, T., Tabata, R., & Orimo, H. (1991) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(91)90057-7 · Cited by 23
Measurement of Lung Density By X-ray Computed Tomography
Wollmer, P., Jakobsson, K., Albin, M. C., Albrechtsson, U., Brauer, K., Eriksson, L. T., Jonson, B., Skerfving, S., & Tylén, U. (1987) · CHEST Journal · doi:10.1378/chest.91.6.865 · Cited by 23
Pulmonary Gas Exchange and Acid‐Base Balance During Exercise
Stickland, M. K., Lindinger, M. I., Olfert, I. M., Heigenhauser, G. J. F., & Hopkins, S. R. (2013) · Comprehensive physiology · doi:10.1002/j.2040-4603.2013.tb00500.x · Cited by 22
Respiratory mechanics after heart-lung and bilateral lung transplantation
Chacon, R. A., Corris, P. A., Dark, J. H., & Gibson, G. J. (1997) · Thorax · doi:10.1136/thx.52.8.718 · Cited by 22
Effects of chronic cigarette smoke inhalation on the development of senile lung in senescence-accelerated mouse
Teramoto, S., Uejima, Y., Oka, T., Teramoto, K., Matsuse, T., Ouchi, Y., & Fukuchi, Y. (1997) · Research in Experimental Medicine · doi:10.1007/s004330050050 · Cited by 21
Senescent Expression of Genes Coding Tropoelastin, Elastase, Lysyl Oxidase, and Tissue Inhibitors of Metalloproteinases in Rat Vocal Folds
Ding, H., & Gray, S. D. (2001) · Journal of Speech Language and Hearing Research · doi:10.1044/1092-4388(2001/026 · Cited by 21
Pulmonary Function and Expiratory Flow Limitation in Acute Cervical Spinal Cord Injury
Alvisi, V., Marangoni, E., Zannoli, S., Uneddu, M., Uggento, R., Farabegoli, L., Ragazzi, R., Milic‐Emili, J., Belloni, G. P., Alvisi, R., et al. (2012) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2012.04.015 · Cited by 20
Ventilatory limitations in patients with HFpEF and obesity
Babb, T. G., Balmain, B. N., Tomlinson, A. R., Hynan, L. S., Levine, B. D., MacNamara, J. P., & Sarma, S. (2023) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2023.104167 · Cited by 18
Improved lung function and quality of life following increased elastic recoil after lung volume reduction surgery in emphysema
Norman, M., Hillerdal, G., Orre, L., Jorfeldt, L., LARSEN, F. F., Cederlund, K., Zetterberg, G., & Unge, G. (1998) · Respiratory Medicine · doi:10.1016/s0954-6111(98)90513-3 · Cited by 18
Biomechanics of the Aging Lung Parenchyma
Suki, B., & Bartolák‐Suki, E. (2014) · Engineering materials and processes · doi:10.1007/978-3-319-03970-1_5 · Cited by 17
Maximum volumes in excised human lungs: effects of age, emphysema, and formalin inflation.
Berend, N., Skoog, C., Waszkiewicz, L., & Thurlbeck, W. M. (1980) · Thorax · doi:10.1136/thx.35.11.859 · Cited by 17
A Survey of Practices of Pulmonary Function Interpretation in Laboratories in Northeast Ohio
Mohanka, M. R., McCarthy, K. J., Xu, M., & Stoller, J. K. (2011) · CHEST Journal · doi:10.1378/chest.11-1141 · Cited by 16
Aspects physiologiques du vieillissement respiratoire
Guénard, H. J.-P., & Rouatbi, S. (2004) · Revue des Maladies Respiratoires · doi:10.1016/s0761-8425(04)71558-2 · Cited by 16
Non-small cell lung cancer therapy: safety and efficacy in the elderly
Fabian, T., Glotzer, Bakhos, & Chandramouli, M. (2013) · Drug Healthcare and Patient Safety · doi:10.2147/dhps.s41199 · Cited by 15
Influence of Kyphosis on the Age-Related Decline in Pulmonary Function.
Teramoto, S., Suzuki, M., Matsuse, T., Ohga, E., Katayama, H., Nagase, T., Fukuchi, Y., & Ouchi, Y. (1998) · Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics · doi:10.3143/geriatrics.35.23 · Cited by 15
The Aging Respiratory System: Anesthetic Strategies to Minimize Perioperative Pulmonary Complications
Cartin‐Ceba, R., Šprung, J., Gajic, O., & Warner, D. O. (2008) · Springer eBooks · doi:10.1007/978-0-387-72527-7_11 · Cited by 15
Long-term Evaluation of Penicillamine or Cyclofenil in Systemic Sclerosis:Results from a Two-year Randomized Study
Åkesson, A., Blom-Bülow, B., Scheja, A., Wollmer, P., Valind, S., & Wollheim, F. A. (1992) · Scandinavian Journal of Rheumatology · doi:10.3109/03009749209099231 · Cited by 15
Causal Effects of Body Mass Index on Airflow Obstruction and Forced Mid-Expiratory Flow: A Mendelian Randomization Study Taking Interactions and Age-Specific Instruments Into Consideration Toward a Life Course Perspective
Probst-Hensch, N. M., Jeong, A., Stolz, D., Pons, M., Soccal, P. M., Bettschart, R. W., Jarvis, D., Holloway, J. W., Kronenberg, F., Imboden, M., et al. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.584955 · Cited by 15
Frequency dependence of dynamic compliance in patients with rheumatoid arthritis.
Hills, E. A., Davies, S., & Geary, M. (1979) · Thorax · doi:10.1136/thx.34.6.755 · Cited by 14
Lobar pressure-volume characteristics of excised human lungs.
Berend, N., Skoog, C., & Thurlbeck, W. M. (1981) · Thorax · doi:10.1136/thx.36.4.290 · Cited by 14

Authors: Knudson, R. J., Clark, D. F., Kennedy, T. C., & Knudson, D. E.
Venue: Journal of Applied Physiology
Publisher: American Physiological Society
Published: 1977-12-01
Volume: 43
Issue: 6
Pages: 1054-1062
ISSN: 0161-7567 (ISSN-L)
8750-7587
1522-1601
DOI: 10.1152/jappl.1977.43.6.1054
OpenAlex: W2336497260
Cited by: 197
References: 0
Citations by year: 2026: 4 · 2025: 4 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 8 · 2018: 4 · 2017: 5 · 2016: 3 · 2015: 6 · 2014: 2 · 2013: 6 · 2012: 5
FWCI: 4.56
Type: journal article
Language: en
Open access: closed
Locations: Journal of Applied Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Keywords: aging, lung elastic recoil, respiratory mechanics, plethysmography, maximal expiratory flow, lung volume, sex differences, older adults, alpha-1-antitrypsin
MeSH terms: Adult, Aged, Aging, Female, Humans, Lung, Lung Compliance, Male, Maximal Expiratory Flow Rate, Middle Aged, Sex Factors, Total Lung Capacity, Vital Capacity

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effect of aging alone on mechanical properties of the normal adult human lung

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks