The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Active muscle and whole body lactate kinetics after endurance training in men
Abstract
We evaluated the hypotheses that endurance training decreases arterial lactate concentration ([lactate]a) during continuous exercise by decreasing net lactate release (L˙) and appearance rates (R a) and increasing metabolic clearance rate (MCR). Measurements were made at two intensities before [45 and 65% peak O 2 consumption (V˙o 2 peak)] and after training [65% pretrainingV˙o 2 peak, same absolute workload (ABT), and 65% posttrainingV˙o 2 peak, same relative intensity (RLT)]. Nine men (27.4 ± 2.0 yr) trained for 9 wk on a cycle ergometer, 5 times/wk at 75%V˙o 2 peak. Compared with the 65%V˙o 2 peak pretraining condition (4.75 ± 0.4 mM), [lactate]a decreased at ABT (41%) and RLT (21%) ( P < 0.05). L˙ decreased at ABT but not at RLT. Leg lactate uptake and oxidation were unchanged at ABT but increased at RLT. MCR was unchanged at ABT but increased at RLT. We conclude that 1) active skeletal muscle is not solely responsible for elevated [lactate]a; and 2) training increases leg lactate clearance, decreases whole body and leg lactate production at a given moderate-intensity power output, and increases both whole body and leg lactate clearance at a high relative power output.
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Citations
Cites
Glucose metabolism during leg exercise in man
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Disposal of blood [1-13c] lactate in humans during rest and exercise
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“(31) reported 82% oxidation of lactate Rd at 50% maximal O2 consumption and 78% oxidation at 75% maximal O2 consumption.”
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Metadata
- Authors
- Bergman, B. C., Wolfel, E. E., Butterfield, G. E., Lopaschuk, G. D., Casazza, G. A., Horning, M. A., & Brooks, G. A.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1999-11-01
- Volume
- 87
- Issue
- 5
- Pages
- 1684-1696
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2199833104
- Cited by
- 279
- References
- 3
- FWCI
- 10.79
- Type
- journal article
- Language
- en
- Open access
- closed
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