Smaller muscle ATP reduction in women than in men by repeated bouts of sprint exercise.
Abstract
It was hypothesized that the reduction of high-energy phosphates in muscle after repeated sprints is smaller in women than in men. Fifteen healthy and physically active women and men with an average age of 25 yr (range of 19-42 yr) performed three 30-s cycle sprints (Wingate test) with 20 min of rest between sprints. Repeated blood and muscle samples were obtained. Freeze-dried pooled muscle fibers of types I and II were analyzed for high-energy phosphates and their breakdown products and for glycogen. Accumulation of plasma ATP breakdown products, plasma catecholamines, and blood lactate, as well as glycogen reduction in type I fibers, was all lower in women than in men during sprint exercise. Repeated sprints induced smaller reduction of ATP and smaller accumulation of IMP and inosine in women than in men in type II muscle fibers, with no gender differences in changes of ATP and its breakdown products during the bouts of exercise themselves. This indicates that the smaller ATP reduction in women than in men during repeated sprints was created during recovery periods between the sprint exercises and that women possess a faster recovery of ATP via reamination of IMP during these recovery periods.
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Three bouts of 30 s all-out cycling with 20 min rest between sprints decreased glycogen content by approximately 50%.
“Three bouts of 30 s all-out cycling with 20 min rest between sprints decreased glycogen content by approximately 50%”
From Effect of Exercise Training on Fat Loss—Energetic Perspectives and the Role of Improved Adipose Tissue Function and Body Fat Distribution (2021) · cites this paper as Esbjörnsson-Liljedahl et al., 2002
A single 30-second Wingate sprint can reduce muscle glycogen stores in the vastus lateralis by 20-30%.
“It has consistently been shown that a single 30-second Wingate sprint can reduce muscle glycogen stores in the vastus lateralis by 20-30% (Esbjornsson-Liljedahl et al. 1999;Parolin et al. 1999;Esbjornsson-Liljedahl et al. 2002;Gibala et al. 2009).”
From Towards the minimal amount of exercise for improving metabolic health: beneficial effects of reduced-exertion high-intensity interval training (2012) · cites this paper as Esbjornsson-Liljedahl et al. 2002
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- Authors
- Esbjörnsson-Liljedahl, M., Bodin, K., & Jansson, E.
- Affiliations
- Karolinska Institutet, Department of Medical Laboratory Sciences and Technology, Division of Clinical Physiology, Huddinge University Hospital, 141 86 Stockholm, Sweden
- Karolinska Institutet (SE)
- ORCID
- Jansson, Eva
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 2002-09-01
- Volume
- 93
- Issue
- 3
- Pages
- 1075-1083
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2169034533
- Cited by
- 142
- References
- 32
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 14 · 2023: 13 · 2022: 8 · 2021: 13 · 2020: 10 · 2019: 5 · 2018: 6 · 2017: 5 · 2016: 5 · 2015: 7 · 2014: 7 · 2013: 6 · 2012: 4
- FWCI
- 2.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- high-energy phosphates, muscle ATP, repeated sprint exercise, sex differences, women, men, inosine, muscle glycogen, type I muscle fibers, fast-twitch muscle, catecholamines, blood lactate, Wingate test
- MeSH terms
- Adenosine Triphosphate, Adult, Blood, Female, Humans, Male, Oxidation-Reduction, Physical Endurance, Sex Characteristics, Time Factors, Exercise, Muscle, Skeletal
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