Cited by 2,061Motor Control and AdaptationVisual perception and processing mechanismsMultisensory perception and integration

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Posterior parietal association cortex of the monkey: command functions for operations within extrapersonal space

Mountcastle, V. B., Lynch, J. C., Georgopoulos, A., Sakata, H., Acuna, C.·1975·Journal of Neurophysiology

DOI 10.1152/jn.1975.38.4.871

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Abstract

Experiments were made on the posterior parietal association cortical areas 5 and in 17 hemispheres of 11 monkeys, 6 M. mulatta and 5 M. arctoides. The electrical signs of the activity of single cortical cells were recorded with microelectrodes in waking animals as they carried out certain behavioral acts in response to a series of sensory cues. The behavioral paradigms were one for detection alone, and a second for detection plus projection of the arm to contact a stationary or moving target placed at arm's length. Of the 125 microelectrode penetrations made, 1,451 neurons were identified in terms of the correlation of their activity with the behavioral acts and their sensitivity or lack of it to sensory stimuli delivered passively; 180 were studied quantitatively. The locations of cortical neurons were identified in serial sections; 94 penetrations and 1,058 neurons were located with certainty. About two-thirds of the neurons of area 5 were activated by passive rotation of the limbs at their joints; of these, 82% were related to single, contralateral joints, 10% to two or more contralateral joints, 6% to ipsilateral, and 2% to joints on both sides of the body. A few of the latter were active during complex bodily postures. A large proportion of area 5 neurons were relatively insensitive to passive joint rotations, as compared with similar neurons of the postcentral gyrus, but were driven to high rates of discharge when the same joint was rotated during an active movement of the animal...

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“neurophysiological perspective, thus providing a ‘positive image’ of some of the disorders of parietal patients (Mountcastle et al., 1975).”
BackgroundSelf-citation
The effects of bilateral frontal eye-field, posterior parietal or superior collicular lesions on visual search in the rhesus monkey
Latto, R. (1978) · Brain Research · doi:10.1016/0006-8993(78)90216-0 · Cited by 90
The history of the neurophysiology and neurology of the parietal lobe
Berlucchi, G., & Vallar, G. (2018) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63622-5.00001-2 · Cited by 89
Somatosensory cortex participates in the consolidation of human motor memory
Kumar, N., Manning, T. F., & Ostry, D. J. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000469 · Cited by 95
“There is also considerable evidence for the involvement of parietal cortex more generally in the control of movement [38, 39] (see Kalaska [40] for review) and each participant, and bars indicate the average across participants for each group.”
Background
Transmitter receptors reveal segregation of cortical areas in the human superior parietal cortex: Relations to visual and somatosensory regions
Scheperjans, F., Palomero‐Gallagher, N., Grefkes, C., Schleicher, A., & Zilles, K. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.06.028 · Cited by 89
“1) (Mountcastle et al., 1975; Vogt and Vogt, 1919).”
Background
Somatosensory evoked potentials following proprioceptive stimulation of finger in man
Mima, T., Terada, K., Maekawa, M., Nagamine, T., Ikeda, A., & Shibasaki, H. (1996) · Experimental Brain Research · doi:10.1007/bf00227300 · Cited by 89
Overlapping representation of fingers in the somatosensory cortex (area 2) of the conscious monkey
Iwamura, Y., Tanaka, M., & Hikosaka, O. (1980) · Brain Research · doi:10.1016/0006-8993(80)91139-7 · Cited by 89
Specialized subregions in the cat motor cortex: A single unit analysis in the behaving animal
Vicario, D. S., Martin, J. H., & Ghez, C. P. (1983) · Experimental Brain Research · doi:10.1007/bf00237872 · Cited by 89
Time‐varying coupling of EEG oscillations predicts excitability fluctuations in the primary motor cortex as reflected by motor evoked potentials amplitude: An EEG‐TMS study
Ferreri, F., Vecchio, F., Ponzo, D., Pasqualetti, P., & Rossini, P. M. (2013) · Human Brain Mapping · doi:10.1002/hbm.22306 · Cited by 91
“…in the delta range might therefore partially represent this functional unbinding of the motor cortex from the posterior areas’ inhibitory control when a highly excitable or active condition is required [see also the active centroinhibitory surround organization by Mountcastle et al., 1975].”
Background
Graspable Objects Grab Attention More Than Images Do
Gómez, M. A., Skiba, R. M., & Snow, J. C. (2017) · Psychological Science · doi:10.1177/0956797617730599 · Cited by 97
“The key question is whether real objects interfere with attention because they afford grasping (Gallivan et al., 2009; Iriki et al., 1996; Mountcastle et al., 1975) or whether they require more detailed and richer visual processing (and incongruence in the visual domain results in greater competition).”
Background
Top-down modulation of attention by emotion
Mohanty, A., & Sussman, T. J. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00102 · Cited by 101
“IPL and IPS (area LIP) neurons are sensitive to the motivational value of stimuli in monkeys (Mountcastle et al., 1975; Bushnell et al., 1981; Sugrue et al., 2004) and limbic regions such as amygdala are important in assessing the motivational salience of stimuli in humans (Pessoa et al.”
The Brain and Human Behavior
Teuberi, H.-L. (1978) · Springer eBooks · doi:10.1007/978-3-642-46354-9_28 · Cited by 87
Response fields of intraparietal neurons quantified with multiple saccadic targets
Platt, M. L., & Glimcher, P. W. (1998) · Experimental Brain Research · doi:10.1007/s002210050438 · Cited by 86
“In at least two previous reports (Mountcastle et al. 1975; Blatt et al. 1990), neurons with visual and saccade-associated”
Partially Mixed Selectivity in Human Posterior Parietal Association Cortex
Zhang, C. Y., Aflalo, T., Revechkis, B., Rosario, E. R., Ouellette, D. S., Pouratian, N., & Andersen, R. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.040 · Cited by 91
“…these inputs for processing more cognitive functions such as spatial awareness, attention, and action planning, and delivers the outcomes of the associative process to more motor regions of the frontal cortex (Balint, 1909; Holmes, 1918; Mountcastle et al., 1975; Ungerleider and Mishkin, 1982).”
Background
Activation of human mesial cortex during somatosensory target detection task
Forss, N., Merlet, I., Vanni, S., Hämäläinen, M., Mauguı̀ere, F., & Hari, R. (1996) · Brain Research · doi:10.1016/0006-8993(96)00633-6 · Cited by 86
Visuo‐motor transformations for arm reaching
Lacquaniti, F., & Caminiti (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00040.x · Cited by 87
“during reaction time or movement time, reflecting a preplanned desired position or ‘command function’ (Mountcastle et al., 1975), rather than current kinematics.”
BackgroundInfluential
Adaptation and learning in control of voluntary movement by the central nervous system
Kawato, M. (1988) · Advanced Robotics · doi:10.1163/156855389x00127 · Cited by 85
Reach and Gaze Representations in Macaque Parietal and Premotor Grasp Areas
Lehmann, S. J., & Scherberger, H. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5568-12.2013 · Cited by 86
“The posterior parietal cortex is known to process visual information for the guidance of actions (Hyvärinen and Poranen, 1974; Mountcastle et al., 1975; Jeannerod et al., 1995).”
Background
Been There, Seen That: A Neural Mechanism for Performing Efficient Visual Search
Mirpour, K., Arcizet, F., Ong, W. S., & Bisley, J. W. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00688.2009 · Cited by 88
Hierarchical versus parallel processing in tactile object recognition: A behavioural-neuroanatomical study of aperceptive tactile agnosia
Bohlhalter, S. (2002) · Brain · doi:10.1093/brain/awf245 · Cited by 84
PET Study of Pointing With Visual Feedback of Moving Hands
Inoue, K., Kawashima, R., Satoh, K., Kinomura, S., Goto, R., Koyama, M., Sugiura, M., Ito, M., & Fukuda, H. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.117 · Cited by 86
The superior parietal lobule of primates: a sensory-motor hub for interaction with the environment
Passarelli, L., Gamberini, M., & Fattori, P. (2021) · Journal of Integrative Neuroscience · doi:10.31083/j.jin.2021.01.334 · Cited by 91
“that SPL is not only a structure deputed to the integration of diverse types of sensory information [54, 81, 82], particularly somatic and visual, but it also plays a role in the control of so-”
Background
Audio-Spatial Deficits in Humans: Differential Effects Associated with Left Versus Right Hemisphere Parietal Damage
Pinek, B., Duhamel, J., Cavé, C., & Brouchon, M. (1989) · Cortex · doi:10.1016/s0010-9452(89)80035-8 · Cited by 83
The role of the supplementary motor area in externally timed movement: the influence of predictability of movement timing
Thickbroom, G. W., Byrnes, M. L., Sacco, P., Ghosh, S., Morris, I. T., & Mastaglia, F. L. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02588-9 · Cited by 83
Feeling form: the neural basis of haptic shape perception
Yau, J. M., Kim, S. S., Thakur, P. H., & Bensmaı̈a, S. J. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00598.2015 · Cited by 84
Neglect, Extinction, and the Cortical Streams of Visual Processing
Milner, A. D. (1997) · Springer eBooks · doi:10.1007/978-3-642-60661-8_1 · Cited by 83
Opiate receptor distribution in the cerebral cortex of the Rhesus monkey.
Wise, S., & Herkenham, M. (1982) · Science · doi:10.1126/science.6289441 · Cited by 85
Removing the superior colliculus silences eye movements normally evoked from stimulation of the parietal and occipital eye fields
Keating, E. G., Gooley, S. G., Pratt, S. E., & Kelsey, J. E. (1983) · Brain Research · doi:10.1016/0006-8993(83)90971-x · Cited by 84
Activity of postcentral cortical neurons of the monkey during conditioned movements of a deafferented limb
Bioulac, B. H., & Lamarre, Y. (1979) · Brain Research · doi:10.1016/0006-8993(79)90576-6 · Cited by 78
The human posterior parietal cortex: effective connectome, and its relation to function
Rolls, E. T., Deco, G., Huang, C., & Feng, J. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac266 · Cited by 85
“Further evidence that the reward value of touch and related visual stimuli are not represented in parietal cortex is that “visual fixation neurons” (Mountcastle et al. 1975) do not reflect the reward value of visual stimuli measured by a devaluation experiment in which macaques were fed to satiety, and the neurons did…”
BackgroundMethod
Neural Systems Activated during Visual Mental Imagery
Thompson, W. L., & Kosslyn, S. M. (2000) · Elsevier eBooks · doi:10.1016/b978-012692545-6/50020-9 · Cited by 82

Authors: Mountcastle, V. B., Lynch, J. C., Georgopoulos, A., Sakata, H., & Acuna, C.
ORCID: Lynch, J. C.
Venue: Journal of Neurophysiology
Publisher: American Physiological Society
Published: 1975-07-01
Volume: 38
Issue: 4
Pages: 871-908
ISSN: 0022-3077 (ISSN-L)
1522-1598
DOI: 10.1152/jn.1975.38.4.871
OpenAlex: W2177960617
Cited by: 2,061
References: 40
Citations by year: 2026: 11 · 2025: 10 · 2024: 13 · 2023: 17 · 2022: 21 · 2021: 28 · 2020: 32 · 2019: 51 · 2018: 25 · 2017: 31 · 2016: 32 · 2015: 37 · 2014: 29 · 2013: 43 · 2012: 39
FWCI: 23.34
Type: journal article
Language: en
Open access: closed
Locations: Journal of Neurophysiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
Keywords: area 5, extrapersonal space, single-unit recording, joint rotation, passive limb movement, arm reaching, target detection, postcentral gyrus, macaque, marmoset
MeSH terms: Animals, Haplorhini, Brain Mapping, Exploratory Behavior, Eye Movements, Joints, Macaca, Mechanoreceptors, Models, Neurological, Motor Skills, Neural Pathways, Neurons, Orientation, Parietal Lobe, Posture, Proprioception, Skin, Space Perception, Time Factors, Visual Perception

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Posterior parietal association cortex of the monkey: command functions for operations within extrapersonal space

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