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Brain Glucose Transporters: Relationship to Local Energy Demand
Abstract
Glucose, the major fuel in the brain, is transported across the cell membranes by facilitated diffusion mediated by glucose transporter proteins. Essentially two types of glucose transporters are localized in the membranes of brain endothelial cells, astrocytes, and neurons. Their densities are well adjusted to changes in local energy demand.
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Glut3 handles most glucose uptake in neurons.
“Glucose transporter 3 (Glut3) handles most glucose uptake in neurons.”
From Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington’s disease mice (2014) · cites this paper as [10]
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Research works printed but not linked: 17
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- 10.1002/jnr.490220413 · DOI
- 10.1074/jbc.275.7.4607 · DOI
- 10.1042/bj3330713 · DOI
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- 10.1097/00004647-199601000-00008 · DOI
- 10.2337/diab.39.9.1040 · DOI · Paper page
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- 10.1046/j.1471-4159.1994.62010240.x · DOI
- 10.1152/ajpendo.1994.267.4.E605 · DOI
- 10.1016/0165-3806(95)00177-8 · DOI
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Metadata
- Authors
- Duelli, R., & Kuschinsky, W.
- Affiliations
- R. Duelli and W. Kuschinsky are in the Department of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany.
- Venue
- Physiology
- Publisher
- American Physiological Society
- Published
- 2001-04
- Volume
- 16
- Issue
- 2
- Pages
- 71-76
- ISSN
- 1548-9213
- 1548-9221
- Cited by
- 85
- References
- 0
- Language
- en
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