Systemic Iron Homeostasis

Cites (282)

Items 201–278 of 278

1. H+-Coupled Divalent Metal-Ion Transporter-1
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2. Hepatic oxidative DNA damage correlates with iron overload in chronic hepatitis C patients
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4. Hemojuvelin-Neogenin Interaction Is Required for Bone Morphogenic Protein-4-induced Hepcidin Expression
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6. Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice
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7. The Role of Hepatocyte Hemojuvelin in the Regulation of Bone Morphogenic Protein-6 and Hepcidin Expression in Vivo
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8. Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice
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9. A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
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10. FERRITIN IN SERUM
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11. A possible role for secreted ferritin in tissue iron distribution
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12. High-throughput screening of small molecules identifies hepcidin antagonists
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13. Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice
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14. Real-World Use of Iron Chelators
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15. Liver hepcidin mRNA correlates with iron stores, but not inflammation, in patients with chronic hepatitis C.
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16. Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation
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17. Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice
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18. Evidence for the multimeric structure of ferroportin.
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19. mRNA expression of iron regulatory genes in β-thalassemia intermedia and β-thalassemia major mouse models
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20. Tocilizumab, a humanized anti-interleukin-6 receptor antibody, improved anemia in monkey arthritis by suppressing IL-6-induced hepcidin production
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21. Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling
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22. Subcellular Localization of Iron and Heme Metabolism Related Proteins at Early Stages of Erythrophagocytosis
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23. Iron nutrition in the UK: getting the balance right
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24. Hemochromatosis and Vibrio vulnificus Wound Infections
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25. A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis
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27. Known and potential roles of transferrin in iron biology
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28. Duodenal Reductase Activity and Spleen Iron Stores Are Reduced and Erythropoiesis Is Abnormal in Dcytb Knockout Mice Exposed to Hypoxic Conditions3
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29. Inherited disorders of iron metabolism
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30. Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis
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31. Vibrio vulnificus septicemia in a patient with the hemochromatosis HFE C282Y mutation
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32. Nramp1 equips macrophages for efficient iron recycling
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33. Yersinia enterocolitica Infection with Multiple Liver Abscesses Uncovering a Primary Hemochromatosis
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34. Is the iron regulatory hormone hepcidin a risk factor for alcoholic liver disease?
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35. A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats
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36. Understanding the Structure/Activity Relationships of the Iron Regulatory Peptide Hepcidin
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37. Iron Imports. V. Transport of iron through the intestinal epithelium
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38. Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs)
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39. Transgenic HFE‐dependent induction of hepcidin in mice does not require transferrin receptor‐2
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40. Mutations in the Gene Encoding DMT1: Clinical Presentation and Treatment
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41. Wild-type and mutant ferroportins do not form oligomers in transfected cells
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42. Multiple Hepatic Abscesses Due to Yersinia enterocolitica Infection Secondary to Primary Haemochromatosis
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43. Not all DMT1 mutations lead to iron overload
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44. Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice
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45. Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice
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46. Meat and health
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47. Growth differentiation factor 15 in patients with congenital dyserythropoietic anaemia (CDA) type II
    Guillem Casanovas, Dorine W. Swinkels, Sandro Altamura, Klaus Schwarz, Coby M. Laarakkers, Hans-Juergen Gross, Markus Wiesneth, H. Heimpel, Martina Ulrike Muckenthaler · 2011 · Journal of Molecular Medicine
48. Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia
    Paola Trombini, Tiziana Angela Coliva, Elizabeta Nemeth, Raffaella Mariani, Tomas Ganz, Andrea Biondi, Alberto Piperno · 2007 · Haematologica
49. Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages
    Anne Auriac, Alexandra Willemetz, François Canonne‐Hergaux · 2010 · Haematologica
50. Serum hepcidin but not prohepcidin may be an effective marker for anemia of inflammation (AI)
    Sasu, Barbra J., Li, Hongyan, Rose, Mark J., Arvedson, Tara L., Doellgast, George, Molineux, Graham · 2010 · Blood Cells Molecules and Diseases
51. The Hypoxia-Inducible Factor–C/EBPα Axis Controls Ethanol-Mediated Hepcidin Repression
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52. Natural History and Management ofHFE-Hemochromatosis
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53. Iron Stores Modulate Hepatic Hepcidin Expression by an HFE-Independent Pathway
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54. Expression of growth differentiation factor 15 is not elevated in individuals with iron deficiency secondary to volunteer blood donation
    Tanno, Toshihiko, Rabel, Antoinette, Lee, Y. Terry, Yau, Yu Ying, Leitman, Susan F., Miller, Jeffery L. · 2010 · Transfusion
55. Serum levels of the hepcidin-20 isoform in a large general population: The Val Borbera study
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56. Ferroportin is a monomer in vivo in mice
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57. Ferroportin: Lack of evidence for multimers
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58. Binding of Hepcidin to Plasma Proteins
    Outi Itkonen, Ulf‐Håkan Stenman, Jaakko Parkkinen, Rabah Soliymani, Marc Baumann, Esa K Hämäläinen · 2012 · Clinical Chemistry
59. Prohepcidin localises to the Golgi compartment and secretory pathway in hepatocytes
    Daniel F. Wallace, Lesa Summerville, Patricia E. Lusby, V. Nathan Subramaniam · 2005 · Journal of Hepatology
60. Belgrade Rats Display Liver Iron Loading
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61. Targeting the Hepcidin Pathway with RNAi Therapeutics for the Treatment of Anemia
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62. Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice
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63. Exploring the Role of Hepcidin, an Antimicrobial and Iron Regulatory Peptide, in Increased Iron Absorption in β‐Thalassemia
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64. Regulation of iron metabolism in Hamp −/− mice in response to iron-deficient diet
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65. Discovery and preclinical characterization of a novel hepcidin antagonist with tunable PK/PD properties for the treatment of anemia in different patient populations
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66. A Case of Congenital Dyserythropoietic Anemia Type 1 in a Japanese Adult with a CDAN1 Gene Mutation and an Inappropriately Low Serum Hepcidin-25 Level
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67. Impaired regulation of serum hepcidin during phlebotomy in patients with chronic hepatitis C
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68. Single and Repeated Dose First-in-Human Study with the Anti-Hepcidin Spiegelmer Nox-H94.
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69. Mining ferritin iron: 2 pathways
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70. Transcripts of ceruloplasmin but not hepcidin, both major iron metabolism genes, exhibit a decreasing pattern along the portocentral axis of mouse liver
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71. Iron balance in thalassemia.
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72. The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron.
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73. Intestinal Response to the Body's Requirement for Iron
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74. Randomized Double Blind Placebo Controlled PK/PD Study On the Effects of a Single Intravenous Dose of the Anti-Hepcidin Spiegelmer Nox-H94 On Serum Iron During Experimental Human Endotoxemia
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75. Alcohol intake and iron overload: Another role for hepcidin?
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76. Target TMPRSS6 for the Treatment of Hereditary Hemochromatosis
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77. Functional expression in Xenopus oocytes reveals that human ferroportin is an iron exporter shared with zinc
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78. Intestinal brush‐border Na + /H + exchangers are required for iron homeostasis in the mouse
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