Clear Cell Adenocarcinoma Arising from Abdominal Wall Endometriosis
Open accessAbstract
Endometriosis is a frequent benign disorder. Malignancy arising in extraovarian endometriosis is a rare event. A 49-year-old woman is presented with a large painful abdominal wall mass. She underwent a myomectomy, 20 years before, for uterus leiomyoma. Computed tomography suggested that this was a desmoid tumor and she underwent surgery. Histological examination showed a clear cell adenocarcinoma associated with endometriosis foci. Pelvic ultrasound, computed tomography, and endometrial curettage did not show any malignancy or endometriosis in the uterus and ovaries. Adjuvant chemotherapy was recommended, but the patient was lost to follow up. Six months later, she returned with a recurrence of the abdominal wall mass. She was given chemotherapy and then she was reoperated.
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Some authors describe other prognostic factors such as the size of the mass at the time of diagnosis, which could play a role in a better outcome, especially if the masses range between 4 and 9 cm.
“Some authors describe other prognostic factors such as the size of the mass at the time of diagnosis, which could play a role in a better outcome, especially if the masses range between 4 and 9 cm [63,64,65,66,67,68,69,70,71,72,73,74].”
From Malignancy in Abdominal Wall Endometriosis: Is There a Way to Avoid It? A Systematic Review (2024) · cites this paper as [64]
The Case Report (p. not provided) records an 8.5 cm mass at diagnosis, but does not link its size to a better outcome; the patient later had a recurrence. The Discussion (p. not provided) links prognosis to histological type and disease location, not mass size. Searches for a size-based prognostic factor and a 4–9 cm range found no supporting passage. (LLM, conf=0.76)
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- Authors
- Achach, T., Rammeh, S., Trabelsi, A., Ltaief, R., Ben Abdelkrim, S., Mokni, M., & Korbi, S.
- Affiliations
- Hôpital Farhat Hached (TN)
- Department of Pathology, University Teaching Hospital Farhat Hached, Sousse 4000, Tunisia
- Venue
- Journal of Oncology
- Publisher
- Hindawi Limited
- Published
- 2008
- Volume
- 2008
- Pages
- 1-3
- ISSN
- 1687-8450 (ISSN-L)
- 1687-8469
- PMC
- PMC2648644
- OpenAlex
- W1980140077
- Cited by
- 26
- References
- 13
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 2 · 2012: 2
- FWCI
- 0.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Oncology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Metastasis and carcinoma case studies
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Keywords
- clear cell adenocarcinoma, endometriosis-associated cancer, abdominal wall endometriosis, aggressive fibromatosis, abdominal wall mass, leiomyoma, adjuvant chemotherapy, tumor recurrence
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