The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Relationship between Serum and Brain Carotenoids,α-Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study
Open accessAbstract
Oxidative stress is involved in age-related cognitive decline. The dietary antioxidants, carotenoids, tocopherols, and vitamin A may play a role in the prevention or delay in cognitive decline. In this study, sera were obtained from 78 octogenarians and 220 centenarians from the Georgia Centenarian Study. Brain tissues were obtained from 47 centenarian decedents. Samples were analyzed for carotenoids,α-tocopherol, and retinol using HPLC. Analyte concentrations were compared with cognitive tests designed to evaluate global cognition, dementia, depression and cognitive domains (memory, processing speed, attention, and executive functioning). Serum lutein, zeaxanthin, andβ-carotene concentrations were most consistently related to better cognition (P<0.05) in the whole population and in the centenarians. Only serum lutein was significantly related to better cognition in the octogenarians. In brain, lutein andβ-carotene were related to cognition with lutein being consistently associated with a range of measures. There were fewer significant relationships forα-tocopherol and a negative relationship between brain retinol concentrations and delayed recognition. These findings suggest that the status of certain carotenoids in the old may reflect their cognitive function. The protective effect may not be related to an antioxidant effect given thatα-tocopherol was less related to cognition than these carotenoids.
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Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Sheikh (1986) · doi:10.1300/j018v05n01_09 · Cited by 7,236
The Global Deterioration Scale for assessment of primary degenerative dementia
(1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.9.1136 · Cited by 4,986
Wechsler Adult Intelligence Scale-III
Ryan, J. J., & Lopez, S. J. (2001) · Understanding Psychological Assessment · doi:10.1007/978-1-4615-1185-4_2 · Cited by 3,731
Antioxidant activity of carotenoids
Stahl, W., & Sies, H. (2003) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(03)00030-x · Cited by 1,414
Wyss-Coray (2006) · doi:10.1038/nm1484 · Cited by 1,284
The Control of Short-Term Memory
Atkinson, R. C., & Shiffrin, R. M. (1971) · Scientific American · doi:10.1038/scientificamerican0871-82 · Cited by 1,252
Annual Review of Gerontology and Geriatrics
(1988) · Springer eBooks · doi:10.1007/978-3-662-38443-5 · Cited by 1,188
Snodderly, D. (1995) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.6.1448s · Cited by 799
Morris, M. C. (2002) · JAMA · doi:10.1001/jama.287.24.3230 · Cited by 678
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Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan
Johnson, E. J. (2014) · Nutrition Reviews · doi:10.1111/nure.12133 · Cited by 438
Self-citationThe Effect of Lutein on Eye and Extra-Eye Health
Buscemi, S., Corleo, D., Di Pace, F., Petroni, M. L., Satriano, A., & Marchesini, G. (2018) · Nutrients · doi:10.3390/nu10091321 · Cited by 260
Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study
Morris, M. C., Wang, Y., Barnes, L. L., Bennett, D. A., Dawson-Hughes, B., & Booth, S. L. (2018) · Neurology · doi:10.1212/wnl.0000000000004815 · Cited by 252
Moran, N. E., Mohn, E. S., Hason, N., Erdman, J. W., & Johnson, E. J. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy025 · Cited by 205
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Metadata
- Authors
- Johnson, E. J., Vishwanathan, R., Johnson, M. A., Hausman, D. B., Davey, A., Scott, T. M., Green, R. C., Miller, L. S., Gearing, M., Woodard, J., Nelson, P. T., Chung, H.-Y., Schalch, W., Wittwer, J., & Poon, L. W.
- Venue
- Journal of Aging Research
- Publisher
- Wiley
- Published
- 2013
- Volume
- 2013
- Pages
- 1-13
- ISSN
- 2090-2204 (ISSN-L)
- 2090-2212
- OpenAlex
- W2141325921
- Cited by
- 264
- References
- 64
- FWCI
- 11.48
- Type
- journal article
- Language
- en
- Open access
- gold
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- Johnson, E. J., Vishwanathan, R., Johnson, M. A., Hausman, D. B., Davey, A., Scott, T. M., Green, R. C., Miller, L. S., Gearing, M., Woodard, J., Nelson, P. T., Chung, H.-Y., Schalch, W., Wittwer, J., & Poon, L. W. (2013). Relationship between Serum and Brain Carotenoids,α-Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study. Journal of Aging Research. https://doi.org/10.1155/2013/951786
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