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Cited by 18Adrenal and Paraganglionic TumorsMedical Imaging Techniques and ApplicationsRenal cell carcinoma treatment

MDCT in the differentiation of adrenal masses: comparison between different scan delays for the evaluation of intralesional washout

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Angelelli, Giuseppe, Mancini, Maria Elisabetta, Moschetta, Marco, Pedote, Pasquale, Pignataro, Pasquale, Scardapane, Arnaldo·2013·The Scientific World JOURNAL
DOI 10.1155/2013/957680PMC PMC3606796
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Abstract

PURPOSE: To evaluate the accuracy of the washout in the differential diagnosis between adenomas and nonadenomas and to compare the obtained results in delayed CT scans at 5, 10 and 15 minutes. METHODS: Fifty patients with adrenal masses were prospectively evaluated. CT scans were performed by using a 320-row MDCT device, before and after injection of contrast material. In 25 cases, delayed scans were performed at 5' and 10' (group 1), while in the remaining 25, at 5' and 15' (group 2). Absolute and relative wash-out percentage values (APW and RPW) were calculated. RESULTS: Differential diagnosis between adenomas and nonadenomas was obtained in 48/50 (96%) cases, with sensitivity, specificity, and accuracy values of 96%, 95%, and 96%, respectively. In group 1, APW and RPW values were, respectively, 69.8% and 67.2% at 5' and 75.9% and 73.5% at 10' for adenomas and 25.1% and 15.8% at 5' and 33.5% and 20.5% at 10' for nonadenomas. In group 2, APW and RPW values were 63% and 54.6% at 5' and 73.8% and 65.5% at 15' for adenomas and 22% and 12.5% at 5' and 35.5% and 19.9% at 15' for nonadenomas. CONCLUSIONS: The evaluation of the wash-out values in CT scans performed at 5', 10', and 15' provides comparable diagnostic results. CT scans performed at 5' are, therefore, to be preferred, since they reduce the examination time and patient discomfort.

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  • Only 1 previous study evaluated test performance of CT contrast-enhanced washout in truly incidentally discovered adrenal masses; it reported sensitivity 96% and specificity 95% for differentiating benign from malignant adrenal lesions, but considered only 50 cases.

    “However, only 1 previous study has evaluated the test performance of CT contrast-enhanced washout in the evaluation of truly incidentally discovered adrenal masses (301), that is in patients not undergoing surveillance imaging for previous nonadrenal malignancy. This study reported high sensitivity (96%) and specificity (95%) for differentiating benign from malignant adrenal lesions (301); however”

    From Adrenal incidentaloma (2020) · cites this paper as [301]

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Authors
Angelelli, G., Mancini, M. E., Moschetta, M., Pedote, P., Pignataro, P., & Scardapane, A.
Affiliations
University of Bari Aldo Moro (IT)
Corresponding author
Angelelli, Giuseppe
ORCID
Venue
The Scientific World JOURNAL
Publisher
Wiley
Published
2013-01
Volume
2013
Issue
1
Pages
957680-957680
ISSN
  • 1537-744X (ISSN-L)
  • 2356-6140
DOI
10.1155/2013/957680
PMC
PMC3606796
OpenAlex
W2140112206
Cited by
18
References
30
Citations by year
2024: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 4 · 2017: 1 · 2016: 2
FWCI
0.66
Type
journal article
Language
en
Open access
Licence
Locations
  • The Scientific World JOURNAL (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • AIRUS (submittedVersion)
  • CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Renal cell carcinoma treatment
Keywords
adrenal mass, adrenal adenoma, contrast-enhanced CT, differential diagnosis
MeSH terms
Adenoma, Adrenal Gland Neoplasms, Adrenal Glands, Adult, Aged, Aged, 80 and over, Contrast Media, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Prospective Studies, Sensitivity and Specificity, Time Factors, Tomography, X-Ray Computed, Reproducibility of Results

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