Cited by 120Neurogenesis and neuroplasticity mechanismsMaternal Mental Health During Pregnancy and PostpartumNeuroendocrine regulation and behavior

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The Maternal Brain: An Organ with Peripartal Plasticity

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Hillerer, Katharina Maria, Jacobs, Volker Rudolf, Fischer, Thorsten, Aigner, Ludwig·2014·Neural Plasticity

DOI 10.1155/2014/574159PMC PMC4026981

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Abstract

The time of pregnancy, birth, and lactation, is characterized by numerous specific alterations in several systems of the maternal body. Peripartum-associated changes in physiology and behavior, as well as their underlying molecular mechanisms, have been the focus of research since decades, but are still far from being entirely understood. Also, there is growing evidence that pregnancy and lactation are associated with a variety of alterations in neural plasticity, including adult neurogenesis, functional and structural synaptic plasticity, and dendritic remodeling in different brain regions. All of the mentioned changes are not only believed to be a prerequisite for the proper fetal and neonatal development, but moreover to be crucial for the physiological and mental health of the mother. The underlying mechanisms apparently need to be under tight control, since in cases of dysregulation, a certain percentage of women develop disorders like preeclampsia or postpartum mood and anxiety disorders during the course of pregnancy and lactation. This review describes common peripartum adaptations in physiology and behavior. Moreover, it concentrates on different forms of peripartum-associated plasticity including changes in neurogenesis and their possible underlying molecular mechanisms. Finally, consequences of malfunction in those systems are discussed.

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321
Astrocytes, from brain glue to communication elements: the revolution continues
Volterra, A., & Meldolesi, J. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1722 · Cited by 1,837
The role of medial prefrontal cortex in memory and decision making
Euston, D. R., Gruber, A. J., & McNaughton, B. L. (2012) · Neuron · doi:10.1016/j.neuron.2012.12.002 · Cited by 1,541
Immune modulation of learning, memory, neural plasticity and neurogenesis
Yirmiya, R., & Goshen, I. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.10.015 · Cited by 1,483
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
Snyder, J. S., Soumier, A., Brewer, M., Pickel, J., & Cameron, H. A. (2011) · Nature · doi:10.1038/nature10287 · Cited by 1,473
Adult neurogenesis and functional plasticity in neuronal circuits
Lledo, P., Alonso, M., & Grubb, M. S. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1867 · Cited by 1,425
Implantation and the placenta: key pieces of the development puzzle
Cross, J. C., Werb, Z., & Fisher, S. J. (1994) · Science · doi:10.1126/science.7985020 · Cited by 1,354
Pathogenesis and genetics of pre-eclampsia
Roberts, J., & Cooper, D. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03577-7 · Cited by 1,279
Natural killer cells and pregnancy
Moffett-King, A. (2002) · Nature Reviews Immunology · doi:10.1038/nri886 · Cited by 1,235
The course of anxiety and depression through pregnancy and the postpartum in a community sample
Heron, J., O'Connor, T. G., Evans, J., Golding, J., & Glover, V. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2003.08.004 · Cited by 1,151 · cited 1×
“postpartum anxiety (5–12%) [11, 12], or in even more serious”
Background

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Show all 243 references

Research works printed but not linked: 21

1995, Journal of Clinical Endocrinology and Metabolism, 80, 2954
10.1210/jc.86.10.4798 · DOI · Paper page
10.1210/en.140.6.2843 · DOI
1998, Journal of Physiology, 508, part 1, 289
1996, Advances in Experimental Medicine and Biology, 395, 395
2002, American Journal of Neuroradiology, 23, 19
1982, Archives of Pathology and Laboratory Medicine, 106, 360
1998, Acta Radiologica, 39, 64
2013, BMC Neuroscience, 14, article 7
1996, Advances in Experimental Medicine and Biology, 395, 269
1975, Experimental Brain Research, 22, 525
2010, Frontiers in Behavioral Neuroscience, 4, article 176
1986, Presumed olfactory exchanges between mother and neonate in humans, 101
2010, Neuroscience, 227, 201
1993, American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 264, R555
10.1210/en.138.2.756 · DOI
1993, Obstetrics and Gynecology, 81, 764
2013, Hormones and Behavior, 65, 32
2013, Frontiers in Neuroscience, 7
2000, Advances in Experimental Medicine and Biology, 468, 175
2011, Acta Neurologica Belgica, 111, 10

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Authors: Hillerer, K. M., Jacobs, V. R., Fischer, T., & Aigner, L.
Affiliations: Paracelsus Medical University (AT)
Corresponding author: Aigner, Ludwig
ORCID: Fischer, Thorsten
Aigner, Ludwig
Venue: Neural Plasticity
Publisher: Hindawi Limited
Published: 2014
Volume: 2014
Pages: 1-20
ISSN: 1687-5443 (ISSN-L)
2090-5904
DOI: 10.1155/2014/574159
PMC: PMC4026981
OpenAlex: W2055237339
Cited by: 120
References: 243
Citations by year: 2026: 7 · 2025: 6 · 2024: 11 · 2023: 8 · 2022: 13 · 2021: 6 · 2020: 19 · 2019: 13 · 2018: 14 · 2017: 3 · 2016: 13 · 2015: 6 · 2014: 1
FWCI: 0.80
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (unspecified)
Locations: Neural Plasticity (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
Funders: State Government of Salzburg (HEALTH-F2-2011-278850, P-12/01/001-FIS)
Medical Private University Salzburg (HEALTH-F2-2011-278850, P-12/01/001-FIS)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Keywords: maternal brain, pregnancy, lactation, births, adult neurogenesis, synaptic plasticity, dendritic remodeling, preeclampsia, maternal mental health, fetal and neonatal development
MeSH terms: Adult, Animals, Brain, Female, Humans, Mothers, Neuronal Plasticity, Pregnancy, Peripartum Period

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The Maternal Brain: An Organ with Peripartal Plasticity

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