Cited by 120Neurogenesis and neuroplasticity mechanismsMaternal Mental Health During Pregnancy and PostpartumNeuroendocrine regulation and behavior

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The Maternal Brain: An Organ with Peripartal Plasticity

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Hillerer, Katharina Maria, Jacobs, Volker Rudolf, Fischer, Thorsten, Aigner, Ludwig·2014·Neural Plasticity

DOI 10.1155/2014/574159PMC PMC4026981

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Abstract

The time of pregnancy, birth, and lactation, is characterized by numerous specific alterations in several systems of the maternal body. Peripartum-associated changes in physiology and behavior, as well as their underlying molecular mechanisms, have been the focus of research since decades, but are still far from being entirely understood. Also, there is growing evidence that pregnancy and lactation are associated with a variety of alterations in neural plasticity, including adult neurogenesis, functional and structural synaptic plasticity, and dendritic remodeling in different brain regions. All of the mentioned changes are not only believed to be a prerequisite for the proper fetal and neonatal development, but moreover to be crucial for the physiological and mental health of the mother. The underlying mechanisms apparently need to be under tight control, since in cases of dysregulation, a certain percentage of women develop disorders like preeclampsia or postpartum mood and anxiety disorders during the course of pregnancy and lactation. This review describes common peripartum adaptations in physiology and behavior. Moreover, it concentrates on different forms of peripartum-associated plasticity including changes in neurogenesis and their possible underlying molecular mechanisms. Finally, consequences of malfunction in those systems are discussed.

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321
Astrocytes, from brain glue to communication elements: the revolution continues
Volterra, A., & Meldolesi, J. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1722 · Cited by 1,837
The role of medial prefrontal cortex in memory and decision making
Euston, D. R., Gruber, A. J., & McNaughton, B. L. (2012) · Neuron · doi:10.1016/j.neuron.2012.12.002 · Cited by 1,541
Immune modulation of learning, memory, neural plasticity and neurogenesis
Yirmiya, R., & Goshen, I. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.10.015 · Cited by 1,483
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
Snyder, J. S., Soumier, A., Brewer, M., Pickel, J., & Cameron, H. A. (2011) · Nature · doi:10.1038/nature10287 · Cited by 1,473
Adult neurogenesis and functional plasticity in neuronal circuits
Lledo, P., Alonso, M., & Grubb, M. S. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1867 · Cited by 1,425
Implantation and the placenta: key pieces of the development puzzle
Cross, J. C., Werb, Z., & Fisher, S. J. (1994) · Science · doi:10.1126/science.7985020 · Cited by 1,354
Pathogenesis and genetics of pre-eclampsia
Roberts, J., & Cooper, D. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03577-7 · Cited by 1,279
Natural killer cells and pregnancy
Moffett-King, A. (2002) · Nature Reviews Immunology · doi:10.1038/nri886 · Cited by 1,235
The course of anxiety and depression through pregnancy and the postpartum in a community sample
Heron, J., O'Connor, T. G., Evans, J., Golding, J., & Glover, V. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2003.08.004 · Cited by 1,151 · cited 1×
“postpartum anxiety (5–12%) [11, 12], or in even more serious”
Background
Diagnosis and Management of Gestational Hypertension and Preeclampsia
Sibai, B. M. (2003) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(03)00475-7 · Cited by 1,149
Epidemiology of Puerperal Psychoses
Kendell, R. E., Chalmers, J. C., & Platz, C. (1987) · British Journal of Psychiatry · doi:10.1192/bjp.150.5.662 · Cited by 1,119
Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
Czéh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., van Kampen, M., Bartolomucci, A., & Fuchs, E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211427898 · Cited by 1,114
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.
Park, J. E., Chen, H. H., Winer, J., Houck, K. A., & Ferrara, N. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47298-5 · Cited by 1,112
Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons
Woolley, C., Gould, E., Frankfurt, M., & McEwen, B. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-12-04035.1990 · Cited by 1,107
Adult neurogenesis: from precursors to network and physiology
Abrous, D. N., Koehl, M., & Le Moal, M. (2005) · Physiological Reviews · doi:10.1152/physrev.00055.2003 · Cited by 971
Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting
Liston, C., Miller, M. M., Goldwater, D. S., Radley, J. J., Rocher, A. B., Hof, P. R., Morrison, J. H., & McEwen, B. S. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1184-06.2006 · Cited by 968
LYSOSOME FUNCTION IN THE REGULATION OF THE SECRETORY PROCESS IN CELLS OF THE ANTERIOR PITUITARY GLAND
Smith, R. E., & Farquhar, M. G. (1966) · The Journal of Cell Biology · doi:10.1083/jcb.31.2.319 · Cited by 957
Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino acid receptors
Magarin˜os, A. M., & McEwen, B. S. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00259-l · Cited by 863
Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex
Radley, J. J., Rocher, A. B., Miller, M., Janssen, W. G. M., Liston, C., Hof, P. R., McEwen, B. S., & Morrison, J. H. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhi104 · Cited by 820
Electrophysiology of hypothalamic magnocellular neurones secreting oxytocin and vasopressin
Poulain, D. A., & Wakerley, J. B. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90044-6 · Cited by 816
Core Conductor Theory and Cable Properties of Neurons
Rall, W. (1977) · Comprehensive physiology · doi:10.1002/cphy.cp010103 · Cited by 783
Brain oxytocin: A key regulator of emotional and social behaviours in both females and males
Neumann, I. D. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01726.x · Cited by 743
Pregnancy-Stimulated Neurogenesis in the Adult Female Forebrain Mediated by Prolactin
Shingo, T., Gregg, C., Enwere, E. K., Fujikawa, H., Hassam, R., Geary, C. L., Cross, J. C., & Weiss, S. (2003) · Science · doi:10.1126/science.1076647 · Cited by 711
Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors
Champagne, F., Diorio, J., Sharma, S., & Meaney, M. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.221224598 · Cited by 707
CELL ADHESION MOLECULES: Implications for a Molecular Histology
Edelman, G. M., & Crossin, K. L. (1991) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.60.070191.001103 · Cited by 705
Maternal Care Associated with Methylation of the Estrogen Receptor-α1b Promoter and Estrogen Receptor-α Expression in the Medial Preoptic Area of Female Offspring
Champagne, F. A., Weaver, I. C. G., Diorio, J., Dymov, S., Szyf, M., & Meaney, M. J. (2006) · Endocrinology · doi:10.1210/en.2005-1119 · Cited by 675
Repeated restraint stress suppresses neurogenesis and induces biphasic PSA‐NCAM expression in the adult rat dentate gyrus
Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02513.x · Cited by 657
BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation
Taupin, P. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.08.002 · Cited by 645
Prospective study of postpartum depression: Prevalence, course, and predictive factors.
O’Hara, M. W., Neunaber, D. J., & Zekoski, E. M. (1984) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.93.2.158 · Cited by 632
Inhibition of neurogenesis interferes with hippocampus‐dependent memory function
Winocur, G., Wojtowicz, J. M., Sekeres, M. J., Snyder, J. S., & Wang, S. Z. (2006) · Hippocampus · doi:10.1002/hipo.20163 · Cited by 601
Adult hippocampal neurogenesis is involved in anxiety-related behaviors
Revest, J.-M., Dupret, D., Koehl, M., Funk-Reiter, C., Grosjean, N., Piazza, P.-V., & Abrous, D. N. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.15 · Cited by 549
Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions
Rutishauser, U. S. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10041-2 · Cited by 541
Blood vessels and nerves: common signals, pathways and diseases
Carmeliet, P. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1158 · Cited by 513
Stress During Gestation Alters Postpartum Maternal Care and the Development of the Offspring in a Rodent Model
Champagne, F. A., & Meaney, M. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.016 · Cited by 510
Structural Plasticity and Hippocampal Function
Leuner, B., & Gould, E. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.093008.100359 · Cited by 478
Angiogenesis and vasculogenesis in pregnancy
Zygmunt, M., Herr, F., Münstedt, K., Lang, U., & Liang, O. D. (2003) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(03)00168-4 · Cited by 473
Prevalence of depressive symptoms in late pregnancy and postpartum
Josefsson, A., Berg, G., Nordin, C., & Sydsjö, G. (2001) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2001.080003251.x · Cited by 461
Brain Oxytocin Inhibits Basal and Stress‐Induced Activity of the Hypothalamo‐Pituitary‐Adrenal Axis in Male and Female Rats: Partial Action Within the Paraventricular Nucleus
Neumann, Wigger, Torner, Holsboer, & Landgraf (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00442.x · Cited by 452
Prospective study of postpartum depression: Prevalence, course, and predictive factors.
O’Hara, M. W., Neunaber, D. J., & Zekoski, E. M. (1984) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.93.2.158 · Cited by 452
Brain Oxytocin Correlates with Maternal Aggression: link to Anxiety
Bosch, O. J., Meddle, S. L., Beiderbeck, D. I., Douglas, A. J., & Neumann, I. D. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1342-05.2005 · Cited by 439
The expectant brain: adapting for motherhood
Brunton, P. J., & Russell, J. A. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2280 · Cited by 407
Brain oxytocin: differential inhibition of neuroendocrine stress responses and anxiety-related behaviour in virgin, pregnant and lactating rats
Neumann, I. D., Torner, L., & Wigger, A. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00433-9 · Cited by 402
Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women
Heinrichs, M., Meinlschmidt, G., Neumann, I., Wagner, S., Kirschbaum, C., Ehlert, U., & Hellhammer, D. H. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.10.7919 · Cited by 386
Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone‐dependent mechanism
Tanapat, P., Hastings, N. B., Rydel, T. A., Galea, L. A. M., & Gould, E. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1297 · Cited by 385
Suppression of hypothalmic-pituitary-adrenal axis responses to stress in lactating women
Altemus, M. M., Deuster, P. A., Galliven, E., Carter, C. S., & Gold, P. W. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.10.7559880 · Cited by 383
Direct Stimulation of Adult Neural Stem Cells In Vitro and Neurogenesis In Vivo by Vascular Endothelial Growth Factor
Schänzer, A., Wachs, F., Wilhelm, D., Acker, T., Cooper‐Kuhn, C. M., Beck, H., Winkler, J., Aigner, L., Plate, K. H., & Kuhn, H. G. (2004) · Brain Pathology · doi:10.1111/j.1750-3639.2004.tb00060.x · Cited by 379
Self-citation
Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis
Czéh, B., Welt, T., Fischer, A., Erhardt, A., Schmitt, W. B., Müller, M. B., Toschi, N., Fuchs, E., & Keck, M. E. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01457-9 · Cited by 376
Attenuated neuroendocrine responses to emotional and physical stressors in pregnant rats involve adenohypophysial changes
Neumann, I. D., Johnstone, H. A., Hatzinger, M., Liebsch, G., Shipston, M. J., Russell, J. A., Landgraf, R., & Douglas, A. J. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.289br.x · Cited by 365
Motivational systems and the neural circuitry of maternal behavior in the rat
Numan, M. (2007) · Developmental Psychobiology · doi:10.1002/dev.20198 · Cited by 358
Depression and anxiety during pregnancy and six months postpartum: a follow‐up study
Andersson, L., Poromaa, I. S., Wulff, M., Åström, M., & Bixo, M. (2006) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1080/00016340600697652 · Cited by 357
Pilot Study of Extracorporeal Removal of Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia
Thadhani, R., Kisner, T., Hagmann, H., Boßung, V., Noack, S., Schaarschmidt, W., Jank, A., Kribs, A., Cornely, O. A., Kreyssig, C., et al. (2011) · Circulation · doi:10.1161/circulationaha.111.034793 · Cited by 355
Severe Maternal Morbidity Associated with Hypertensive Disorders in Pregnancy in the United States
Zhang, J., Meikle, S., & Trumble, A. C. (2003) · Hypertension in Pregnancy · doi:10.1081/prg-120021066 · Cited by 351
Plasma oxytocin concentration during pregnancy is associated with development of postpartum depression
Skrundz, M., Bolten, M., Nast, I., Hellhammer, D. H., & Meinlschmidt, G. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.74 · Cited by 349
Cytokines of the Placenta and Extra-placental Membranes: Roles and Regulation During Human Pregnancy and Parturition
Bowen, J. M., Chamley, L., Keelan, J. A., & Mitchell, M. D. (2002) · Placenta · doi:10.1053/plac.2001.0782 · Cited by 342
NEURAL MECHANISMS OF MAMMALIAN OLFACTORY LEARNING
Brennan, P., & Keverne, E. B. (1997) · Progress in Neurobiology · doi:10.1016/s0301-0082(96)00069-x · Cited by 337
Local origins of some GABAergic projections to the paraventricular and supraoptic nuclei of the hypothalamus in the rat
Roland, B. L., & Sawchenko, P. E. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903320109 · Cited by 334
Physiological Mapping of Local Inhibitory Inputs to the Hypothalamic Paraventricular Nucleus
Boudaba, C., Szabó, K., & Tasker, J. G. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-22-07151.1996 · Cited by 333
The milk-ejection reflex of the rat: a 20-to 40-fold acceleration in the firing of paraventricular neurones during oxytocin release
WAKERLEY, J. B., & LINCOLN, D. W. (1973) · Journal of Endocrinology · doi:10.1677/joe.0.0570477 · Cited by 327
Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions
Rutishauser, U. S. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10041-2 · Cited by 325
Mechanisms of Disease: pre-eclampsia
Noris, M., Perico, N., & Remuzzi, G. (2005) · Nature Reviews Nephrology · doi:10.1038/ncpneph0035 · Cited by 324
Molecular mechanisms of preeclampsia
Mutter, W. P., & Karumanchi, S. A. (2007) · Microvascular Research · doi:10.1016/j.mvr.2007.04.009 · Cited by 321
Neural control of maternal behaviour and olfactory recognition of offspring
Kendrick, K. M., Da Costa, A. P. C., Broad, K. D., Ohkura, S., Guevara, R., Lévy, F., & Keverne, E. B. (1997) · Brain Research Bulletin · doi:10.1016/s0361-9230(97)00218-9 · Cited by 311
Chronic high corticosterone reduces neurogenesis in the dentate gyrus of adult male and female rats
Brummelte, S., & Galea, L. A. M. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.04.023 · Cited by 309
Natural Variations in Maternal Care Are Associated with Estrogen Receptor α Expression and Estrogen Sensitivity in the Medial Preoptic Area
Champagne, F. A., Weaver, I. C. G., Diorio, J. C., Sharma, S., & Meaney, M. J. (2003) · Endocrinology · doi:10.1210/en.2003-0564 · Cited by 305
Consequences of Neural Cell Adhesion Molecule Deficiency on Cell Migration in the Rostral Migratory Stream of the Mouse
Chazal, G., Durbec, P. L., Jankovski, A., Rougon, G. N., & Cremer, H. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-04-01446.2000 · Cited by 304
Inhibition of post-partum maternal behaviour in the rat by injecting an oxytocin antagonist into the cerebral ventricles
van Leengoed, E., Kerker, E., & Swanson, H. H. (1987) · Journal of Endocrinology · doi:10.1677/joe.0.1120275 · Cited by 300
Adaptive Responses of the Maternal Hypothalamic‐Pituitary‐Adrenal Axis during Pregnancy and Lactation
Brunton, P. J., Russell, J. A., & Douglas, A. J. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01735.x · Cited by 298
Motherhood improves learning and memory
Kinsley, C. H., Madonia, L., Gifford, G. W., Tureski, K., Griffin, G. R., Lowry, C., Williams, J., Collins, J., McLearie, H., & Lambert, K. G. (1999) · Nature · doi:10.1038/45957 · Cited by 297
No stress please! Mechanisms of stress hyporesponsiveness of the maternal brain
Slattery, D. A., & Neumann, I. D. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.145896 · Cited by 293
The Pituitary Gland in Pregnancy: A Clinicopathologic and Immunohistochemical Study of 69 Cases
Scheithauer, B. W., Sano, T., Kovács, K., Young, W. F., Ryan, N., & Randall, R. V. (1990) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)60946-x · Cited by 278
How immune mechanisms are affected by pregnancy
Luppi, P. (2003) · Vaccine · doi:10.1016/s0264-410x(03)00331-1 · Cited by 269
Anxiolytic and Anti-Stress Effects of Brain Prolactin: Improved Efficacy of Antisense Targeting of the Prolactin Receptor by Molecular Modeling
Torner, L., Toschi, N., Pohlinger, A., Landgraf, R., & Neumann, I. D. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-09-03207.2001 · Cited by 266
Placenta Growth Factor
Persico, M. G. (2001) · Birkhäuser Boston eBooks · doi:10.1007/978-1-4612-0213-4_16 · Cited by 260
Vasculogenesis and angiogenesis in the early human placenta
Demir, R., Seval, Y., & Huppertz, B. (2007) · Acta Histochemica · doi:10.1016/j.acthis.2007.02.008 · Cited by 249
Trophoblast pseudo-vasculogenesis: faking it with endothelial adhesion receptors
Damsky, C. H., & Fisher, S. J. (1998) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(98)80043-4 · Cited by 248
Sex, Hormones and Neurogenesis in the Hippocampus: Hormonal Modulation of Neurogenesis and Potential Functional Implications
Galea, L. A. M., Wainwright, S. R., Roes, M., Duarte‐Guterman, P., Chow, C., & Hamson, D. K. (2013) · Journal of Neuroendocrinology · doi:10.1111/jne.12070 · Cited by 247
Integrative Functions of Lactational Hormones in Social Behavior and Stress Managementa
Carter, C. S., & Altemus, M. M. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51918.x · Cited by 241
Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids
Leuner, B., Caponiti, J., & Gould, E. (2011) · Hippocampus · doi:10.1002/hipo.20947 · Cited by 237
ORIGIN AND FATE OF SECRETORY GRANULES IN CELLS OF THE ANTERIOR PITUITARY GLAND*
Farquhar, M. G. (1961) · Transactions of the New York Academy of Sciences · doi:10.1111/j.2164-0947.1961.tb01361.x · Cited by 237
Simultaneous microdialysis in blood and brain: oxytocin and vasopressin release in response to central and peripheral osmotic stimulation and suckling in the rat
Neumann, I., Ludwig, M., Engelmann, M., Pittman, Q. J., & Landgraf, R. (2008) · Neuroendocrinology · doi:10.1159/000126604 · Cited by 236
Motherhood and the hormones of pregnancy modify concentrations of hippocampal neuronal dendritic spines
Kinsley, C. H., Trainer, R., Stafisso-Sandoz, G., Quadros, P. S., Keyser‐Marcus, L., Hearon, C., Meyer, E. A. A., Hester, N. W., Morgan, M. D., & Kozub, F. J. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.05.017 · Cited by 233
Change in brain size during and after pregnancy: study in healthy women and women with preeclampsia.
Oatridge, A., Holdcroft, A., Saeed, N., Hajnal, J. V., Puri, B. K., Fusi, L., & Bydder, G. M. (2002) · PubMed Central · Cited by 232
Pregnancy, the postpartum, and steroid hormones: effects on cognition and mood
Buckwalter, J. G., Stanczyk, F. Z., McCleary, C. A., Bluestein, B. W., Buckwalter, D. K., Rankin, K. P., Chang, L., & Goodwin, T. M. (1999) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00044-4 · Cited by 227
Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus
Banasr, M., Héry, M., Brezun, J. M., & Daszuta, A. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01763.x · Cited by 226
Increased hypothalamic expression of prolactin in lactation: involvement in behavioural and neuroendocrine stress responses
Torner, L., Toschi, N., Nava, G., Clapp, C., & Neumann, I. D. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.01965.x · Cited by 221
Size and shape of the pituitary gland during pregnancy and post partum: measurement with MR imaging.
Elster, A. D., Sanders, T. G., Vines, F. S., & Chen, M. Y. (1991) · Radiology · doi:10.1148/radiology.181.2.1924800 · Cited by 220
Reproductive experience alters hippocampal neurogenesis during the postpartum period in the dam
Pawluski, J. L., & Galea, L. A. M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.07.031 · Cited by 216
Expression of polysialylated neural cell adhesion molecule by proliferating cells in the subependymal layer of the adult rat, in its rostral extension and in the olfactory bulb
Bonfanti, L., & Theodosis, D. T. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90333-6 · Cited by 215
Adult-Born and Preexisting Olfactory Granule Neurons Undergo Distinct Experience-Dependent Modifications of their Olfactory ResponsesIn Vivo
Magavi, S. S. P., Mitchell, B. D., Szentirmai, O., Carter, B. S., & Macklis, J. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2250-05.2005 · Cited by 215
Pituitary-Adrenal Responsiveness during Lactation in Rats
Stern, J. M., Goldman, L., & Levine, S. (2008) · Neuroendocrinology · doi:10.1159/000122167 · Cited by 214
Oxytocin induces morphological plasticity in the adult hypothalamo-neurohypophysial system
Theodosis, D. T., Montagnese, C. M., Rodriguez, F., Vincent, J., & Poulain, D. A. (1986) · Nature · doi:10.1038/322738a0 · Cited by 211
Olfactory Bulb Removal Eliminates Maternal Behavior in the Mouse
Gandelman, R. J., ZARROW, M. X., Denenberg, V. H., & Myers, M. D. (1971) · Science · doi:10.1126/science.171.3967.210 · Cited by 209
Pregnant women become insensitive to cold stress
Kammerer, M. H., Adams, D., von Castelberg, B., & Glover, V. A. S. (2002) · BMC Pregnancy and Childbirth · doi:10.1186/1471-2393-2-8 · Cited by 208
Prolactin-Induced Mitogenesis in the Subventricular Zone of the Maternal Brain during Early Pregnancy Is Essential for Normal Postpartum Behavioral Responses in the Mother
Larsen, C. M., & Grattan, D. R. (2010) · Endocrinology · doi:10.1210/en.2009-1385 · Cited by 205
Experience induces structural and biochemical changes in the adult primate brain
Kozorovitskiy, Y., Gross, C. G., Kopil, C., Battaglia, L., McBreen, M., Stranahan, A. M., & Gould, E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508817102 · Cited by 202
Paternal recognition of adult offspring mediated by newly generated CNS neurons
Mak, G. K., & Weiss, S. (2010) · Nature Neuroscience · doi:10.1038/nn.2550 · Cited by 201
A new chapter in the field of memory: adult hippocampal neurogenesis
Koehl, M., & Abrous, D. N. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07609.x · Cited by 198
Continuous neurogenesis in the adult forebrain is required for innate olfactory responses
Sakamoto, M., Imayoshi, I., Ohtsuka, T., Yamaguchi, M., Mori, K., & Kageyama, R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018782108 · Cited by 198
Functional Magnetic Resonance Imaging Shows Oxytocin Activates Brain Regions Associated with Mother–Pup Bonding during Suckling
Febo, M., Numan, M., & Ferris, C. F. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3604-05.2005 · Cited by 197
Maternal Serum sFlt1 Concentration Is an Early and Reliable Predictive Marker of Preeclampsia
Hertig, A., Berkane, N. B., Lefèvre, G., Toumi, K., Marti, H., Capeau, J., Uzan, S., & Rondeau, É. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.036715 · Cited by 192
Evidence for structural plasticity in the supraoptic nucleus of the rat hypothalamus in relation to gestation and lactation
Theodosis, D. T., & Poulain, D. A. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90222-7 · Cited by 191
Selection, evolution of behavior and animal models in behavioral neuroscience
Parmigiani, S., Palanza, P., Rodgers, J., & Ferrari, P. F. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00029-9 · Cited by 188
Chapter 1 Brain preparations for maternity — adaptive changes in behavioral and neuroendocrine systems during pregnancy and lactation. An overview
Russell, J. A., Douglas, A. J., & Ingram, C. D. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33002-9 · Cited by 187
Lactation Inhibits Stress-Mediated Secretion of Corticosterone and Oxytocin and Hypothalamic Accumulation of Corticotropin-Releasing Factor and Enkephalin Messenger Ribonucleic Acids
Lightman, S. L., & Young, W. S. (1989) · Endocrinology · doi:10.1210/endo-124-5-2358 · Cited by 184
Cell Surface Expression of Polysialic Acid on NCAM Is a Prerequisite for Activity-Dependent Morphological Neuronal and Glial Plasticity
Theodosis, D. T., Bonhomme, R., Vitiello, S., Rougon, G. N., & Poulain, D. A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-23-10228.1999 · Cited by 183
Structural plasticity in the hypothalamic supraoptic nucleus at lactation affects oxytocin-, but not vasopressin-secreting neurones
Theodosis, D. T., Chapman, D. B., Montagnese, C. M., Poulain, D. A., & Morris, J. F. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90038-2 · Cited by 177
Hippocampal morphology is differentially affected by reproductive experience in the mother
Pawluski, J. L., & Galea, L. A. M. (2005) · Journal of Neurobiology · doi:10.1002/neu.20194 · Cited by 176
Changes in anxiety and cognition due to reproductive experience: A review of data from rodent and human mothers
Macbeth, A. H., & Luine, V. N. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.08.011 · Cited by 176
Possible morphological bases for synchronisation of neuronal firing in the rat supraoptic nucleus during lactation
Theodosis, D. T., Poulain, D. A., & Vincent, J. D. (1981) · Neuroscience · doi:10.1016/0306-4522(81)90173-1 · Cited by 176
Priming and remodelling of human placental bed spiral arteries during pregnancy – A Review
Lyall, F. (2005) · Placenta · doi:10.1016/j.placenta.2005.02.010 · Cited by 175
Maternal experience inhibits the production of immature neurons in the hippocampus during the postpartum period through elevations in adrenal steroids
Leuner, B., Mirescu, C., Noiman, L., & Gould, E. (2007) · Hippocampus · doi:10.1002/hipo.20278 · Cited by 174
Mother–infant interactions in free-ranging rhesus macaques: Relationships between physiological and behavioral variables
Maestripieri, D., Hoffman, C. L., Anderson, G. M., Carter, C. S., & Higley, J. D. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2008.12.016 · Cited by 174
Pituitary dimensions and volume measurements in pregnancy and post partum
Dinç, H., Esen, F., Demırcı, A., Sari, A., & Gümele, H. R. (1998) · Acta Radiologica · doi:10.1080/02841859809172152 · Cited by 172
Chapter 8 Peripartum plasticity within the hypothalamo-pituitary-adrenal axis
Lightman, S. L., Windle, R. J., Wood, S. A., Kershaw, Y. M., Shanks, N. M., & Ingram, C. D. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33009-1 · Cited by 171
The fetal vascularisation of term human placental villi
Kaufmann, P., Bruns, U., Leiser, R., Luckhardt, M., & Winterhager, E. (1985) · Anatomy and Embryology · doi:10.1007/bf00316301 · Cited by 170
Chapter 10 Alterations in behavioral and neuroendocrine stress coping strategies in pregnant, parturient and lactating rats
Neumann, I. D. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33011-x · Cited by 169
Regional Changes in Brain Oxytocin Receptors Post‐Partum: Time‐Course and Relationship to Maternal Behaviour
Insel, T. R. (1990) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1990.tb00445.x · Cited by 164
Maternal nurturing is dependent on her innate anxiety: The behavioral roles of brain oxytocin and vasopressin
Bosch, O. J. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.11.012 · Cited by 163
Neurobiology of the Parental Brain
(2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374285-8.x0001-7 · Cited by 161
Stimuli and consequences of dendritic release of oxytocin within the brain
Neumann, I. D. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351252 · Cited by 161
Reduced fearfulness in the lactating rat
Hȧrd, E., & HANSEN, S. (1985) · Physiology & Behavior · doi:10.1016/0031-9384(85)90155-6 · Cited by 161
Maternal stress and high-fat diet effect on maternal behavior, milk composition, and pup ingestive behavior
Purcell, R. H., Sun, B., Pass, L. L., Power, M. L., Moran, T. H., & Tamashiro, K. L. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.05.012 · Cited by 158
Dissociation Between Behavioral and Hormonal Responses to the Forced Swim Stress in Lactating Rats
Walker, C., Trottier, G., Rochford, J. M., & Lavallée, D. (1995) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1995.tb00799.x · Cited by 156
Motherhood mitigates aging-related decrements in learning and memory and positively affects brain aging in the rat
Gatewood, J. D., Morgan, M. D., Eaton, M., McNamara, I. M., Stevens, L. F., Macbeth, A. H., Meyer, E. A. A., Lomas, L. M., Kozub, F. J., Lambert, K. G., et al. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.03.016 · Cited by 155
Reproductive experience differentially affects spatial reference and working memory performance in the mother
Pawluski, J. L., Walker, S. K., & Galea, L. A. M. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.05.016 · Cited by 154
Central Lactogenic Regulation of Maternal Behavior in Rats: Steroid Dependence, Hormone Specificity, and Behavioral Potencies of Rat Prolactin and Rat Placental Lactogen I
Bridges, R. S., Robertson, M. C., Shiu, R. P. C., Sturgis, J. D., Henriquez, B. M., & Mann, P. E. (1997) · Endocrinology · doi:10.1210/endo.138.2.4921 · Cited by 153
Corticotropin-Releasing Factor Inhibits Maternal Aggression in Mice.
Gammie, S. C., Negrón, A., Newman, S. M., & Rhodes, J. S. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.4.805 · Cited by 145
Chapter 11 The actions of prolactin in the brain during pregnancy and lactation
Grattan, D. R. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33012-1 · Cited by 144
Human cytotrophoblasts promote endothelial survival and vascular remodeling through secretion of Ang2, PlGF, and VEGF-C
Zhou, Y., Bellingard, V., Feng, K.-T., McMaster, M., & Fisher, S. J. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00449-4 · Cited by 143
Spatial Working Memory and Hippocampal Size across Pregnancy in Rats
Galea, L. A. M., Ormerod, B. K., Sampath, S., Kostaras, X., Wilkie, D. M., & Phelps, M. T. (2000) · Hormones and Behavior · doi:10.1006/hbeh.1999.1560 · Cited by 141
Vasopressin released within the central amygdala promotes maternal aggression
Bosch, O. J., & Neumann, I. D. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07115.x · Cited by 139
Plasticity in the maternal circuit: Effects of maternal experience on Fos-Lir in hypothalamic, limbic, and cortical structures in the postpartum rat.
Fleming, A. S., & Korsmit, M. (1996) · Behavioral Neuroscience · doi:10.1037//0735-7044.110.3.567 · Cited by 136
Brain plasticity and ion channels
Debanne, D., Daoudal, G., Sourdet, V., & Russier, M. (2003) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2004.01.004 · Cited by 135
The number of pregnancies is a risk factor for Alzheimer's disease
Colucci, M. E. W., Cammarata, S., Assini, A., Croce, R., Clerici, F., Novello, C., Mazzella, L., Dagnino, N., Mariani, C., & Tanganelli, P. (2006) · European Journal of Neurology · doi:10.1111/j.1468-1331.2006.01520.x · Cited by 134
Maternal Behaviour is Associated with Vasopressin Release in the Medial Preoptic Area and Bed Nucleus of the Stria Terminalis in the Rat
Bosch, O. J., Pförtsch, J., Beiderbeck, D. I., Landgraf, R., & Neumann, I. D. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01984.x · Cited by 130
Reorganization of the Dendritic Trees of Oxytocin and Vasopressin Neurons of the Rat Supraoptic Nucleus during Lactation
Stern, J. E., & Armstrong, W. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-03-00841.1998 · Cited by 130
First reproductive experience persistently affects spatial reference and working memory in the mother and these effects are not due to pregnancy or ‘mothering’ alone
Pawluski, J. L., Vanderbyl, B. L., Ragan, K., & Galea, L. A. M. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.017 · Cited by 129
Adrenal steroid receptor immunoreactivity in cells born in the adult rat dentate gyrus
Cameron, H. A., Woolley, C. S., & Gould, E. (1993) · Brain Research · doi:10.1016/0006-8993(93)90524-q · Cited by 129
Early motherhood in rats is associated with a modification of hippocampal function
Darnaudéry, M., Perez-Martin, M., Del Favero, F., Gomez-Roldan, C., Garcia-Segura, L. M., & Maccari, S. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.05.012 · Cited by 128
Osmotic stimulation causes structural plasticity of neurone-glia relationships of the oxytocin but not vasopressin secreting neurones in the hypothalamic supraoptic nucleus
Chapman, D. B., Theodosis, D. T., Montagnese, C. M., Poulain, D. A., & Morris, J. F. (1986) · Neuroscience · doi:10.1016/0306-4522(86)90039-4 · Cited by 127
Estrous cycle, pregnancy, and parity enhance performance of rats in object recognition or object placement tasks
Paris, J. J., & Frye, C. A. (2008) · Reproduction · doi:10.1530/rep-07-0512 · Cited by 126
Synaptic plasticity in the rat supraoptic nucleus during lactation involves GABA innervation and oxytocin neurons: a quantitative immunocytochemical analysis
Gies, U., & Theodosis, D. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-05-02861.1994 · Cited by 125
Exposure to Chronic Pregnancy Stress Reverses Peripartum-Associated Adaptations: Implications for Postpartum Anxiety and Mood Disorders
Hillerer, K. M., Reber, S. O., Neumann, I. D., & Slattery, D. A. (2011) · Endocrinology · doi:10.1210/en.2011-1091 · Cited by 122
Self-citation
Memory loss during pregnancy
Sharp, K., Brindle, P. M., Brown, M. W., & TURNER, G. M. (1993) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1993.tb15232.x · Cited by 121
Giving birth to a new brain: hormone exposures of pregnancy influence human memory
Glynn, L. M. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.01.015 · Cited by 121
Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice
Kiuchi, T., Lee, H., & Mikami, T. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.01.023 · Cited by 116
Alterations of medial preoptic area neurons following pregnancy and pregnancy-like steroidal treatment in the rat
Keyser‐Marcus, L., Stafisso-Sandoz, G., Gerecke, K. M., Jasnow, A. M., Nightingale, L., Lambert, K. G., Gatewood, J. D., & Kinsley, C. H. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00554-8 · Cited by 115
Prolactin cells in the human pituitary. A quantitative immunocytochemical analysis.
Asa, S. L., Penz, G., Kovács, K., & EZRIN, C. (1982) · PubMed · Cited by 114
Disruption of Adult Neurogenesis in the Olfactory Bulb Affects Social Interaction but not Maternal Behavior
Feierstein, C. E., Lazarini, F., Wagner, S., Gabellec, M., de Chaumont, F., Olivo‐Marín, J., Boussin, F. D., Lledo, P., & Gheusi, G. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00176 · Cited by 112
Gestation-induced cell proliferation in the rat brain
Furuta, M., & Bridges, R. S. (2005) · Developmental Brain Research · doi:10.1016/j.devbrainres.2005.01.008 · Cited by 111
Cognition in pregnancy and the first year post‐partum
Crawley, R. A., Dennison, K., & Carter, C. (2003) · Psychology and Psychotherapy Theory Research and Practice · doi:10.1348/14760830260569265 · Cited by 111
Plasticity in the maternal circuit: Effects of maternal experience on Fos-Lir in hypothalamic, limbic, and cortical structures in the postpartum rat.
Fleming, A. S., & Korsmit, M. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.3.567 · Cited by 111
Decrease and Senescence of Endothelial Progenitor Cells in Patients with Preeclampsia
Sugawara, J., Mitsui‐Saito, M., Hayashi, C., Hoshiai, T., Senoo, M., Chisaka, H., Yaegashi, N., & Okamura, K. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0532 · Cited by 110
Immunologic Characteristics of Preeclampsia, a Comprehensive Review
Ahn, H.-K., Park, J.-C., Gilman‐Sachs, A., & Kwak-Kim, J. Y.-H. (2010) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2010.00913.x · Cited by 107
Changes in the intensity of maternal aggression and central oxytocin and vasopressin V1a receptors across the peripartum period in the rat
Caughey, S. D., Klampfl, S. M., Bishop, V. R., Pfoertsch, J., Neumann, I. D., Bosch, O. J., & Meddle, S. L. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02224.x · Cited by 107
Perceptual Attentional Set-Shifting Is Impaired in Rats with Neurotoxic Lesions of Posterior Parietal Cortex
Fox, M. T., Barense, M. D., & Baxter, M. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-02-00676.2003 · Cited by 105
Dendritic Growth in Medial Prefrontal Cortex and Cognitive Flexibility Are Enhanced during the Postpartum Period
Leuner, B., & Gould, E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3388-10.2010 · Cited by 105
Hippocampus-dependent learning influences hippocampal neurogenesis
Epp, J. R., Chow, C., & Galea, L. A. M. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00057 · Cited by 105
Differences in cognitive performance during pregnancy and early motherhood
de Groot, R. H. M., Vuurman, E. F. P. M., Hornstra, G., & Jolles, J. (2006) · Psychological Medicine · doi:10.1017/s0033291706007380 · Cited by 104
The role of endogenous opioids in neurohypophysial and hypothalamo-pituitary-adrenal axis hormone secretory responses to stress in pregnant rats
Douglas, A., Johnstone, H., Wigger, A., Landgraf, R., Russell, J., & Neumann, I. (1998) · Journal of Endocrinology · doi:10.1677/joe.0.1580285 · Cited by 102
Oxytocin receptor activity in the ventrocaudal periaqueductal gray modulates anxiety-related behavior in postpartum rats.
Figueira, R. J., Peabody, M. F., & Lonstein, J. S. (2008) · Behavioral Neuroscience · doi:10.1037/0735-7044.122.3.618 · Cited by 101
Expression of the long form of the prolactin receptor in magnocellular oxytocin neurons is associated with specific prolactin regulation of oxytocin neurons
Kokay, I. C., Bull, P. M., Davis, R. L., Ludwig, M., & Grattan, D. R. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00730.2005 · Cited by 101
Impaired maternal cognitive functioning after pregnancies complicated by severe pre‐eclampsia: a pilot case‐control study
Brussé, I. A., Duvekot, J. J., Jongerling, J., Steegers, E. A. P., & de Koning, I. (2008) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1080/00016340801915127 · Cited by 100
The Many Faces of Postpartum Depression
Beck, C. T., & Indman, P. (2005) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1177/0884217505279995 · Cited by 99
The Noradrenergic Innervation of Identified Hypothalamic Magnocellular Somata and its Contribution to Lactation‐Induced Synaptic Plasticity
Michaloudi, H. C., Majdoubi, M. E., Poulain, D. A., Papadopoulos, G. C., & Theodosis, D. T. (1997) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1997.00583.x · Cited by 99
Objective and subjective memory impairment in pregnancy
Brindle, P. M., Brown, M. W., Brown, J. L., Griffith, H. B., & TURNER, G. M. (1991) · Psychological Medicine · doi:10.1017/s0033291700022285 · Cited by 98
The Hypothalamic‐Pituitary‐Adrenal Axis Response to Endotoxin is Attenuated During Lactation
Shanks, Windle, Perks, Wood, Ingram, I., & Lightman, S. L. (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00400.x · Cited by 97
Quantitative studies on the supraoptic nucleus in the rat. II. Afferent fiber connections
Z�borszky, L., L�r�nth, C., Makara, G. B., & Palkovits, M. (1975) · Experimental Brain Research · doi:10.1007/bf00237352 · Cited by 94
Role of neural guidance signals in blood vessel navigation
Autiero, M., Smet, F. D., CLAES, F., & Carmeliet, P. (2004) · Cardiovascular Research · doi:10.1016/j.cardiores.2004.09.013 · Cited by 94
Prolactin Receptors in the Brain during Pregnancy and Lactation: Implications for Behavior
Grattan, D. R., Pi, X., Andrews, Z. B., Augustine, R. A., Kokay, I. C., Summerfield, M., Todd, B. J., & Bunn, S. J. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1698 · Cited by 93
Cognitive deficits in women after childbirth.
Eidelman, A. I., Hoffmann, N., & Kaitz, M. (1993) · PubMed · Cited by 92
Motherhood‐induced memory improvement persists across lifespan in rats but is abolished by a gestational stress
Lemaire, V., Billard, J., Dutar, P., George, O., Piazza, P. V., Epelbaum, J., Moal, M. L., & Mayo, W. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04870.x · Cited by 90
Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF)
Macbeth, A. H., Scharfman, H. E., MacLusky, N. J., Gautreaux, C., & Luine, V. N. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.08.011 · Cited by 88
Structural plasticity in the rat supraoptic nucleus during gestation, post-partum lactation and suckling-induced pseudogestation and lactation
Montagnese, C. M., Poulain, D. A., Vincent, J. D., & Theodosis, D. T. (1987) · Journal of Endocrinology · doi:10.1677/joe.0.1150097 · Cited by 86
The Glutamatergic Innervation of Oxytocin‐ and Vasopressin‐secreting Neurons in the Rat Supraoptic Nucleus and its Contribution to Lactation‐induced Synaptic Plasticity
Majdoubi, M. E., Poulain, D. A., & Theodosis, D. T. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01600.x · Cited by 86
Lactation-induced plasticity in the supraoptic nucleus augments axodendritic and axosomatic GABAergic and glutamatergic synapses: an ultrastructural analysis using the disector method
Majdoubi, M. E., Poulain, D. A., & Theodosis, D. T. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00193-0 · Cited by 86
Increased expression of both short and long forms of prolactin receptor mRNA in hypothalamic nuclei of lactating rats
Pi, X., & Grattan, D. R. (1999) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0230013 · Cited by 85
Temporary peripartal impairment in memory and attention and its possible relation to oxytocin concentration
Silber, M., Almkvist, O., Larsson, B., & Uvnäs‐Moberg, K. (1990) · Life Sciences · doi:10.1016/0024-3205(90)90566-a · Cited by 83
From stress to postpartum mood and anxiety disorders: How chronic peripartum stress can impair maternal adaptations
Hillerer, K. M., Neumann, I. D., & Slattery, D. A. (2012) · Neuroendocrinology · doi:10.1159/000330445 · Cited by 82
Self-citation
Circulating Endothelial Progenitor Cells during Human Pregnancy
Sugawara, J., Mitsui‐Saito, M., Hoshiai, T., Hayashi, C., Kimura, Y., & Okamura, K. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0541 · Cited by 79
Chapter 22 Pregnancy and postpartum: changes in cognition and mood
Buckwalter, J. G., Buckwalter, D. K., Bluestein, B. W., & Stanczyk, F. Z. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)33023-6 · Cited by 78
Pup exposure differentially enhances foraging ability in primiparous and nulliparous rats
Lambert, K. G., Berry, A. E., Griffin, G. R., Amory, E., Madonia, L., Love, G., & Kinsley, C. H. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.03.012 · Cited by 77
Influence of Ovarian Steroids on the Ultrastructural Plasticity of the Adult Rat Supraoptic Nucleus Induced by Central Administration of Oxytocin
Montagnese, C. M., Poulain, D. A., & Theodosis, D. T. (1990) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.1990.tb00855.x · Cited by 77
Reduced oxytocin response to osmotic stimulus and immobilization stress in lactating rats
Higuchi, T., Honda, K., Takano, S., & Negoro, H. (1988) · Journal of Endocrinology · doi:10.1677/joe.0.1160225 · Cited by 73
Anxiety and maternal aggression in house mice (Mus musculus): A look at interindividual variability.
Maestripieri, D., & D'Amato, F. R. (1991) · Journal of comparative psychology · doi:10.1037/0735-7036.105.3.295 · Cited by 73
Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress
Dagytė, G., Crescente, I., Postema, F., Seguin, L., Gabriel, C., Mocaër, E., den Boer, J. A., & Koolhaas, J. M. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.11.045 · Cited by 71
Pregnant rats show enhanced spatial memory, decreased anxiety, and altered levels of monoaminergic neurotransmitters
Macbeth, A. H., Gautreaux, C., & Luine, V. N. (2008) · Brain Research · doi:10.1016/j.brainres.2008.09.006 · Cited by 71
Induction of rapid, activity‐dependent neuronal–glial remodelling in the adult rat hypothalamus in vitro
Langle, S. L., Poulain, D. A., & Theodosis, D. T. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02741.x · Cited by 71
Decrease in hippocampal neurogenesis during pregnancy: a link to immunity
Rolls, A., Schori, H., London, A., & Schwartz, M. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002126 · Cited by 69
Aggression in the lactating rat: Effects of intruder age and test arena
Erskine, M. S., Denenberg, V. H., & Goldman, B. D. (1978) · Behavioral Biology · doi:10.1016/s0091-6773(78)91148-3 · Cited by 69
Neuropilin ligands in vascular and neuronal patterning
Fantin, A., Maden, C. H., & Ruhrberg, C. (2009) · Biochemical Society Transactions · doi:10.1042/bst0371228 · Cited by 69
The fetal vascularisation of term human placental villi
Leiser, R., Luckhardt, M., Kaufmann, P., Winterhager, E., & Bruns, U. (1985) · Anatomy and Embryology · doi:10.1007/bf00707305 · Cited by 69
Central noradrenergic mechanisms underlying acute stress responses of the Hypothalamo-pituitary-adrenal axis: Adaptations through pregnancy and lactation
Douglas, A. J. (2005) · Stress · doi:10.1080/10253890500044380 · Cited by 68
Postpartum Corticosterone Administration Reduces Dendritic Complexity and Increases the Density of Mushroom Spines of Hippocampal CA 3 Arbours in Dams
Workman, J. L., Brummelte, S., & Galea, L. A. M. (2012) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2012.02380.x · Cited by 68
Gonadal steroid regulation of oxytocin and oxytocin receptor gene expression.
Zingg, H., Rozen, F., Breton, C., Larcher, A., Neculcea, J., Chu, K., Russo, C., & Arslan, A. (1995) · PubMed · Cited by 67
Reduced Response of the Hypothalamo-Pituitary-Adrenal Axis toα 1-Agonist Stimulation during Lactation*
Windle, R. J., Brady, M. M., Kunanandam, T., Costa, A. P. C., Wilson, B. C., Harbuz, M. S., Lightman, S. L., & Ingram, C. D. (1997) · Endocrinology · doi:10.1210/endo.138.9.5405 · Cited by 67
Prescribing physical activity to prevent and manage gestational diabetes
Colberg, S. R. (2013) · World Journal of Diabetes · doi:10.4239/wjd.v4.i6.256 · Cited by 67
Estradiol receptor-α expression in hypothalamic and limbic regions of ewes is influenced by physiological state and maternal experience
Meurisse, M., Gonzalez, A., Delsol, G., Caba, M., Lévy, F., & Poindron, P. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.02.007 · Cited by 66
Regression of redundant lactotrophs in rat pituitary gland after cessation of lactation
Haggi, E. S., Torres, A. I., Maldonado, C. A., & Aoki, A. (1986) · Journal of Endocrinology · doi:10.1677/joe.0.1110367 · Cited by 66

Flagged first, then by citations

Research works printed but not linked: 21

1995, Journal of Clinical Endocrinology and Metabolism, 80, 2954
10.1210/jc.86.10.4798 · DOI · Paper page
10.1210/en.140.6.2843 · DOI
1998, Journal of Physiology, 508, part 1, 289
1996, Advances in Experimental Medicine and Biology, 395, 395
2002, American Journal of Neuroradiology, 23, 19
1982, Archives of Pathology and Laboratory Medicine, 106, 360
1998, Acta Radiologica, 39, 64
2013, BMC Neuroscience, 14, article 7
1996, Advances in Experimental Medicine and Biology, 395, 269
1975, Experimental Brain Research, 22, 525
2010, Frontiers in Behavioral Neuroscience, 4, article 176
1986, Presumed olfactory exchanges between mother and neonate in humans, 101
2010, Neuroscience, 227, 201
1993, American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 264, R555
10.1210/en.138.2.756 · DOI
1993, Obstetrics and Gynecology, 81, 764
2013, Hormones and Behavior, 65, 32
2013, Frontiers in Neuroscience, 7
2000, Advances in Experimental Medicine and Biology, 468, 175
2011, Acta Neurologica Belgica, 111, 10

Sorted by citations

Pregnancy leads to long-lasting changes in human brain structure
Hoekzema, E., Barba-Müller, E., Pozzobon, C., Picado, M., Lucco, F., García-García, D., Soliva, J. C., Tobeña, A., Desco, M., Crone, E. A., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4458 · Cited by 788
Brain plasticity in pregnancy and the postpartum period: links to maternal caregiving and mental health
Barba‐Müller, E., Craddock, S., Carmona, S., & Hoekzema, E. A. (2018) · Archives of Women s Mental Health · doi:10.1007/s00737-018-0889-z · Cited by 261
Population-based neuroimaging reveals traces of childbirth in the maternal brain
de Lange, A. G., Kaufmann, T., van der Meer, D., Maglanoc, L. A., Alnæs, D., Moberget, T., Douaud, G., Andreassen, O. A., & Westlye, L. T. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1910666116 · Cited by 160
Peripheral oxytocin and vasopressin: Biomarkers of psychiatric disorders? A comprehensive systematic review and preliminary meta-analysis
Rutigliano, G., Rocchetti, M., Paloyelis, Y., Gilleen, J., Sardella, A., Cappucciati, M., Palombini, E., Dell’Osso, L., Caverzasi, E., Politi, P., et al. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.04.117 · Cited by 149
Neuroplasticity in the maternal hippocampus: Relation to cognition and effects of repeated stress
Pawluski, J. L., Lambert, K. G., & Kinsley, C. H. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.06.004 · Cited by 134

See all 120

Authors: Hillerer, K. M., Jacobs, V. R., Fischer, T., & Aigner, L.
Affiliations: Paracelsus Medical University (AT)
Corresponding author: Aigner, Ludwig
ORCID: Fischer, Thorsten
Aigner, Ludwig
Venue: Neural Plasticity
Publisher: Hindawi Limited
Published: 2014
Volume: 2014
Pages: 1-20
ISSN: 1687-5443 (ISSN-L)
2090-5904
DOI: 10.1155/2014/574159
PMC: PMC4026981
OpenAlex: W2055237339
Cited by: 120
References: 243
Citations by year: 2026: 7 · 2025: 6 · 2024: 11 · 2023: 8 · 2022: 13 · 2021: 6 · 2020: 19 · 2019: 13 · 2018: 14 · 2017: 3 · 2016: 13 · 2015: 6 · 2014: 1
FWCI: 0.80
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (unspecified)
Locations: Neural Plasticity (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
Funders: State Government of Salzburg (HEALTH-F2-2011-278850, P-12/01/001-FIS)
Medical Private University Salzburg (HEALTH-F2-2011-278850, P-12/01/001-FIS)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Keywords: maternal brain, pregnancy, lactation, births, adult neurogenesis, synaptic plasticity, dendritic remodeling, preeclampsia, maternal mental health, fetal and neonatal development
MeSH terms: Adult, Animals, Brain, Female, Humans, Mothers, Neuronal Plasticity, Pregnancy, Peripartum Period

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The Maternal Brain: An Organ with Peripartal Plasticity

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