The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Peripheral Nerve Reconstruction after Injury: A Review of Clinical and Experimental Therapies
Open accessAbstract
Unlike other tissues in the body, peripheral nerve regeneration is slow and usually incomplete. Less than half of patients who undergo nerve repair after injury regain good to excellent motor or sensory function and current surgical techniques are similar to those described by Sunderland more than 60 years ago. Our increasing knowledge about nerve physiology and regeneration far outweighs our surgical abilities to reconstruct damaged nerves and successfully regenerate motor and sensory function. It is technically possible to reconstruct nerves at the fascicular level but not at the level of individual axons. Recent surgical options including nerve transfers demonstrate promise in improving outcomes for proximal nerve injuries and experimental molecular and bioengineering strategies are being developed to overcome biological roadblocks limiting patient recovery.
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Cites
Waller, A. V. (1850) · Philosophical Transactions of the Royal Society of London · doi:10.1098/rstl.1850.0021 · Cited by 896
Menorca, R. M. G., Fussell, T. S., & Elfar, J. C. (2013) · Hand Clinics · doi:10.1016/j.hcl.2013.04.002 · Cited by 729
Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation
Fu, S., & Gordon, T. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03886.1995 · Cited by 700
Peripheral Nerve Injury and Repair
Lee, S. K., & Wolfe, S. W. (2000) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/00124635-200007000-00005 · Cited by 685
Lundborg, G. (2000) · The Journal of Hand Surgery · doi:10.1053/jhsu.2000.4165 · Cited by 656
Traumatic injury to peripheral nerves
Robinson, L. R. (2000) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(200006)23:6<863::aid-mus4>3.0.co;2-0 · Cited by 601
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The Incidence of Peripheral Nerve Injury in Extremity Trauma
Taylor, C. A., Braza, D., Rice, J. B., & Dillingham, T. (2008) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0b013e31815e6370 · Cited by 554
The anatomy and physiology of nerve injury
Sunderland, S. S. (1990) · Muscle & Nerve · doi:10.1002/mus.880130903 · Cited by 545
The Interfascicular Nerve-Grafting of the Median and Ulnar Nerves
MILLESI, H., MEISSL, G., & BERGER, A. (1972) · The Journal of Bone & Joint Surgery · doi:10.2106/00004623-197254040-00004 · Cited by 495
Cited by
Vijayavenkataraman, S. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.02.003 · Cited by 556
Modern Trends for Peripheral Nerve Repair and Regeneration: Beyond the Hollow Nerve Guidance Conduit
Carvalho, C. R., Oliveira, J. M., & Reis, R. L. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00337 · Cited by 297
Vijayavenkataraman, S., Thaharah, S., Zhang, S., Lu, W. F., & Fuh, J. Y. H. (2019) · Materials & Design · doi:10.1016/j.matdes.2018.11.044 · Cited by 108
Ma, Y., Wang, H., Wang, Q., Cao, X., & Gao, H. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.139424 · Cited by 103
Zhou, W., Rahman, M. S. U., Sun, C., Li, S., Zhang, N., Chen, H., Han, C. C., Xu, S., & Liu, Y. (2024) · Advanced Materials · doi:10.1002/adma.202307805 · Cited by 65
Metadata
- Authors
- Grinsell, D., & Keating, C. P.
- Venue
- BioMed Research International
- Publisher
- Hindawi Limited
- Published
- 2014
- Volume
- 2014
- Pages
- 1-13
- ISSN
- 1110-7243 (ISSN-L)
- 2314-6133
- 2314-6141
- OpenAlex
- W2022308075
- Cited by
- 1,048
- References
- 46
- FWCI
- 12.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.