Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases.
Open accessAbstract
In this article, we review signal transduction pathways through which acupuncture treats nervous system diseases. We electronically searched the databases, including PubMed, MEDLINE, clinical Key, the Cochrane Library, and the China National Knowledge Infrastructure from their inception to December 2018 using the following MeSH headings and keywords alone or in varied combination: acupuncture, molecular, signal transduction, genetic, cerebral ischemic injury, cerebral hemorrhagic injury, stroke, epilepsy, seizure, depression, Alzheimer’s disease, dementia, vascular dementia, and Parkinson’s disease. Acupuncture treats nervous system diseases by increasing the brain-derived neurotrophic factor level and involves multiple signal pathways, including p38 MAPKs, Raf/MAPK/ERK 1/2, TLR4/ERK, PI3K/AKT, AC/cAMP/PKA, ASK1-JNK/p38, and downstream CREB, JNK, m-TOR, NF-κB, and Bcl-2/Bax balance. Acupuncture affects synaptic plasticity, causes an increase in neurotrophic factors, and results in neuroprotection, cell proliferation, antiapoptosis, antioxidant activity, anti-inflammation, and maintenance of the blood-brain barrier.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Acupuncture can increase serum 5-HT, up-regulate anti-inflammatory cytokine IL-10, and reduce proinflammatory cytokine IL-6 and TNF-α.
“Acupuncture can increase the content of serum 5-HT, up-regulate the content of anti-inflammatory cytokine IL-10, and reduce the content of proinflammatory cytokine IL-6 and TNF-α [26].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
Johnson, G. L., & Lapadat, R. (2002) · Science · doi:10.1126/science.1072682 · Cited by 4,295 · see citing works
Ballard, C., Gauthier, S., Corbett, A., Brayne, C., Aarsland, D., & Jones, E. (2011) · The Lancet · doi:10.1016/s0140-6736(10)61349-9 · Cited by 2,336 · see citing works
Pendlebury, S. T., & Rothwell, P. M. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70236-4 · Cited by 1,853 · see citing works
Rapamycin: one drug, many effects
Li, J., Kim, S. G., & Blenis, J. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.01.001 · Cited by 1,287 · see citing works
O'Brien, J. T., & Thomas, A. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00463-8 · Cited by 1,136 · see citing works
Excitotoxicity and stroke: Identifying novel targets for neuroprotection
Lai, T. W., Zhang, S., & Wang, Y. T. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.11.006 · Cited by 1,106 · see citing works
Burns, A., & Iliffe, S. (2009) · BMJ · doi:10.1136/bmj.b158 · Cited by 859 · see citing works
The Role of Neural Plasticity in Depression: From Hippocampus to Prefrontal Cortex
Liu, W., Ge, T., Leng, Y., Pan, Z., Fan, J., Yang, W., & Cui, R. (2017) · Neural Plasticity · doi:10.1155/2017/6871089 · Cited by 640 · see citing works
A Review of the Clinical, Economic, and Societal Burden of Treatment-Resistant Depression: 1996–2013
Mrazek, D. A., Hornberger, J. C., Altar, C. A., & Degtiar, I. (2014) · Psychiatric Services · doi:10.1176/appi.ps.201300059 · Cited by 580 · see citing works
Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction
Goldberg, E. M., & Coulter, D. A. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3482 · Cited by 542 · see citing works
Vitolo, O. V., Sant'Angelo, A., Costanzo, V., Battaglia, F., Arancio, O., & Shelanski, M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172504199 · Cited by 534 · see citing works
An update on the diagnosis and treatment of Parkinson disease
Rizek, P., Kumar, N., & Jog, M. (2016) · Canadian Medical Association Journal · doi:10.1503/cmaj.151179 · Cited by 455 · see citing works
Chavez, L., Huang, S., MacDonald, I. J., Lin, J., Lee, Y., & Chen, Y. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18112270 · Cited by 385 · see citing works
Niranjan, R. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8483-x · Cited by 331 · see citing works
Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke
Sawe, N. A., Steinberg, G. K., & Zhao, H. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21604 · Cited by 238 · see citing works
Tong, L., Balazs, R., Thornton, P. L., & Cotman, C. W. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.5463-03.2004 · Cited by 221 · see citing works
Epilepsy and Inflammation in the Brain: Overview and Pathophysiology
Vezzani, A. (2014) · Epiliepsy currents/Epilepsy currents · doi:10.5698/1535-7511-14.s2.3 · Cited by 207 · see citing works
Wang, R., Li, J. J., Diao, S., Kwak, Y.-D., Liu, L., Zhi, L., Büeler, H., Bhat, N. R., Williams, R. W., Park, E. A., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.03.016 · Cited by 198 · see citing works
Crosstalk Between MAPK/ERK and PI3K/AKT Signal Pathways During Brain Ischemia/Reperfusion
Zhou, J., Du, T., Li, B., Rong, Y., Verkhratsky, A., & Peng, L. (2015) · ASN NEURO · doi:10.1177/1759091415602463 · Cited by 185 · see citing works
Cai, R.-L., Shen, G.-M., Wang, H., & Guan, Y. (2017) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2017.12.002 · Cited by 154 · see citing works
Effects and Mechanisms of Acupuncture Based on the Principle of Meridians
Zhou, W., & Benharash, P. (2014) · Journal of Acupuncture and Meridian Studies · doi:10.1016/j.jams.2014.02.007 · Cited by 152 · see citing works
Role of neuro-immunological factors in the pathophysiology of mood disorders
Bhattacharya, A., Derecki, N. C., Lovenberg, T. W., & Drevets, W. C. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4214-0 · Cited by 149 · see citing works
Acupuncture for patients with mild to moderate Alzheimer’s disease: a randomized controlled trial
Jia, Y., Zhang, X., Yu, J., Han, J., Yu, T., Shi, J., Zhao, L., & Nie, K. (2017) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-017-2064-x · Cited by 138 · see citing works
Neurobiological Mechanisms of Acupuncture for Some Common Illnesses: A Clinician's Perspective
Cheng, K. J. (2013) · Journal of Acupuncture and Meridian Studies · doi:10.1016/j.jams.2013.07.008 · Cited by 137 · see citing works
Lan, L., Tao, J., CHEN, A., Xie, G., Huang, J., Lin, J., Peng, J., & Chen, L. (2012) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2012.1184 · Cited by 136 · see citing works
New-Onset Seizure in Adults and Adolescents
Gavvala, J. R., & Schuele, S. (2016) · JAMA · doi:10.1001/jama.2016.18625 · Cited by 132 · see citing works
Efficacy and safety of acupuncture in children: an overview of systematic reviews
Yang, C., Hao, Z., Zhang, L., & Guo, Q. (2015) · Pediatric Research · doi:10.1038/pr.2015.91 · Cited by 130 · see citing works
The Safety of Acupuncture during Pregnancy: A Systematic Review
Park, J., Sohn, Y., White, A. R., & Lee, H. (2014) · Acupuncture in Medicine · doi:10.1136/acupmed-2013-010480 · Cited by 124 · see citing works
Acupuncture for neurogenesis in experimental ischemic stroke: a systematic review and meta-analysis
Lü, L., Zhang, X., Zhong, L. L. D., Chen, Z., Li, Y., Zheng, G., & Bian, Z. (2016) · Scientific Reports · doi:10.1038/srep19521 · Cited by 122 · see citing works
Fan, A. Y., Miller, D. W., Bolash, B., Bauer, M. J., McDonald, J. L., Alemi, S. F., He, H., Li, Y. M., Matecki, A., Camardella, L., et al. (2017) · Journal of Chinese Integrative Medicine · doi:10.1016/s2095-4964(17)60378-9 · Cited by 120 · see citing works
Kim, Y. R., Kim, H. N., Ahn, S., Choi, Y. H., Shin, H. K., & Choi, B. T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090000 · Cited by 119 · see citing works
Applications of Acupuncture Therapy in Modulating Plasticity of Central Nervous System
Xiao, L., Wang, X., Yang, Y., Yang, J., Cao, Y., Ma, S., Li, T., & Liu, C. (2017) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12724 · Cited by 118 · see citing works
Ishrat, T., Sayeed, I., Atif, F., Hua, F., & Stein, D. G. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.03.008 · Cited by 115 · see citing works
Feng, X., Yang, S., Liu, J., Huang, J., Peng, J., Lin, J., Tao, J., & Chen, L. (2013) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1392 · Cited by 111 · see citing works
An alternative therapy for drug-resistant epilepsy: transcutaneous auricular vagus nerve stimulation
Rong, P., Liu, A., Zhang, J., Wang, Y., Yang, A., Liang, L., Ben, H., Li, L., Liu, R., He, W., et al. (2014) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20131511 · Cited by 108 · see citing works
Liang, X., Liu, X., Li, F.-Q., Luo, Y., Lü, J., Zhang, W.-M., Wang, X.-M., & Han, J.-S. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00513-2 · Cited by 105 · see citing works
Li, X., Guo, F., Zhang, Q., Huo, T., Liu, L., Wei, H., Xiong, L., & Wang, Q. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-37 · Cited by 100 · see citing works
p53 in neurodegenerative diseases and brain cancers
Checler, F., & da Costa, C. A. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.11.009 · Cited by 97 · see citing works
Kim, S., Doo, A.-R., Park, J.-Y., Bae, H., Chae, Y., Shim, I., Lee, H., Moon, W., Lee, H., & Park, H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027566 · Cited by 94 · see citing works
Cheng, C.-Y., Tang, N.-Y., Kao, S.-T., & Hsieh, C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155748 · Cited by 94 · see citing works
Self-citationLee, B., Sur, B., Shim, J., Hahm, D., & Lee, H. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-338 · Cited by 92 · see citing works
Acupuncture improves cognitive deficits and regulates the brain cell proliferation of SAMP8 mice
Cheng, H., Yu, J., Jiang, Z., Zhang, X., Liu, C., Peng, Y., Chen, F., You, Q., Jia, Y., Tian, Q., et al. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2007.12.009 · Cited by 90 · see citing works
Shin, H. K., Lee, S., & Choi, B. T. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.04.029 · Cited by 87 · see citing works
Cheuk, D. K., & Wong, V. C. N. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005062.pub4 · Cited by 85 · see citing works
Liu, W., Zhuo, P., Li, L., Jin, H., Lin, B., Zhang, Y., Liang, S., Wu, J., Huang, J., Wang, Z., et al. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.07.024 · Cited by 83 · see citing works
Liu, W., Wang, X., Yang, S., Huang, J., Xue, X., Zheng, Y., Shang, G., Tao, J., & Chen, L. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.01.045 · Cited by 81 · see citing works
CHEN, A., Lin, Z., Lan, L., Xie, G., Huang, J., Lin, J., Peng, J., Tao, J., & Chen, L. (2012) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2012.1074 · Cited by 80 · see citing works
Xue, X., You, Y., Tao, J., Ye, X., Huang, J., Yang, S., Lin, Z., Hong, Z., Peng, J., & Chen, L. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.10.029 · Cited by 78 · see citing works
Cox, J., Varatharajan, S., & Côté, P. (2016) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2016.6270 · Cited by 73 · see citing works
Liu, X., Zhou, H., Pan, Y., Liang, X., Niu, D.-B., Xue, B., Li, F., He, Q., Wang, X., & Wang, X.-M. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.05.028 · Cited by 69 · see citing works
Lin, J., Chen, C., Yang, H.-B., Chen, Y., & Hung, S. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18091846 · Cited by 69 · see citing works
Cheng, C.-Y., Ho, T., Hsiang, C., Tang, N.-Y., Hsieh, C., Kao, S.-T., & Lee, Y.-C. (2017) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x17500914 · Cited by 68 · see citing works
Self-citationWang, T., Liu, C., Yu, J., Jiang, W., & Han, J. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2008.09.024 · Cited by 67 · see citing works
Liu, W., Shang, G., Yang, S., Huang, J., Xue, X., Lin, Y., Zheng, Y., WANG, X., Wang, L., Lin, R., et al. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2425 · Cited by 67 · see citing works
Shih, C., Liao, C., Sun, M.-F., Su, Y.-C., Wen, C. P., Morisky, D., Sung, F., Hsu, C. Y., & Lin, J.-G. (2015) · Medicine · doi:10.1097/md.0000000000001572 · Cited by 66 · see citing works
Zhao, L., Wang, Y., Sun, N., Liu, X., Li, L., & Shi, J. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.08.034 · Cited by 65 · see citing works
Hippocampal cAMP/PKA/CREB is required for neuroprotective effect of acupuncture
Li, Q., Shi, G., Yang, J., Li, Z.-X., Zhang, Z., He, T., Wang, J., Liu, L., & Liu, C. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.12.001 · Cited by 65 · see citing works
Effect of acupuncture treatment on vascular dementia
Yu, J., Zhang, X., Liu, C., Meng, Y., & Han, J. (2006) · Neurological Research · doi:10.1179/016164106x91951 · Cited by 65 · see citing works
Zeng, B., & Zhao, K. (2016) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12507 · Cited by 64 · see citing works
Tian, T., Sun, Y., Wu, H., Pei, J., Zhang, J., Zhang, Y., Wang, L., Li, B., Wang, L., Shi, J., et al. (2016) · Scientific Reports · doi:10.1038/srep19714 · Cited by 64 · see citing works
Zhang, Y., Lan, R., Wang, J., Li, X., Zhu, D., Yun-zhi, M., Wu, J.-T., & Liu, Z. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.06.032 · Cited by 62 · see citing works
Zhang, M., Xv, G.-H., Wang, W., Meng, D., & Ji, Y. (2016) · Acupuncture in Medicine · doi:10.1136/acupmed-2015-010972 · Cited by 62 · see citing works
Ahn, S., Kim, Y. R., Kim, H. N., Shin, Y., Shin, H. K., & Choi, B. T. (2016) · Scientific Reports · doi:10.1038/srep28646 · Cited by 61 · see citing works
Zhang, H., Qin, F., Liu, A., Sun, Q., Wang, Q., Xie, S., Lu, S.-F., Zhang, D., & Lu, Z. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.11.059 · Cited by 61 · see citing works
Ghaffari, B. D., & Kluger, B. M. (2014) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-014-0451-y · Cited by 59 · see citing works
Lin, R., Chen, J., Li, X., Mao, J., Wu, Y., Zhuo, P., ZHANG, Y., Liu, W., Huang, J., Tao, J., et al. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4751 · Cited by 59 · see citing works
Noh, H.-S., Kwon, S., Cho, S., Jung, W., Moon, S., Park, J., Ko, C., & Park, S.-U. (2017) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2017.08.005 · Cited by 59 · see citing works
Acupuncture in the Treatment of Cancer-Related Psychological Symptoms
Haddad, N., & Palesh, O. G. (2014) · Integrative Cancer Therapies · doi:10.1177/1534735413520181 · Cited by 57 · see citing works
Xu, W., Zheng, D., Liu, Y., Li, J., Yang, L., & Shang, X. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000485947 · Cited by 57 · see citing works
Acupuncture and Moxibustion for Cancer-related Fatigue: a Systematic Review and Meta-analysis
He, X., Wang, Q., & Li, P. (2013) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2013.14.5.3067 · Cited by 55 · see citing works
Xie, G., YANG, S., CHEN, A., Lan, L., Lin, Z., Gao, Y. L., Huang, J., Lin, J., Peng, J., Tao, J., et al. (2013) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2013.1030 · Cited by 54 · see citing works
Du, J., Wang, Q., Hu, B., Peng, Z., Zhao, Y., Ma, L., Xiong, L., Lü, Y., Zhu, X., & Chen, S. (2010) · Brain Research · doi:10.1016/j.brainres.2010.07.034 · Cited by 53 · see citing works
Wang, K., Wu, H., Wang, G., Li, M., Zhang, Z., & Gu, G. (2009) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181b5a234 · Cited by 53 · see citing works
Acupuncture Activates ERK-CREB Pathway in Rats Exposed to Chronic Unpredictable Mild Stress
Lü, J., Liang, J., Wang, J.-R., Hu, L., Tu, Y., & Guo, J. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/469765 · Cited by 53 · see citing works
Zhu, W. X., Wang, X., Du, S., Yan, C.-Q., Yang, N., Lin, L., Shi, G., & Liu, C. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.03.029 · Cited by 52 · see citing works
Lin, R., Lin, Y., Tao, J., Chen, B., Yu, K., Chen, J., Li, X., & Chen, L. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4321 · Cited by 51 · see citing works
Mechanisms Underlying the Antidepressant Response of Acupuncture via PKA/CREB Signaling Pathway
Jiang, H., Zhang, X., Wang, Y., Zhang, H., Li, J., Yang, X., Zhao, B., Zhang, C., Yu, M., Xu, M., et al. (2017) · Neural Plasticity · doi:10.1155/2017/4135164 · Cited by 51 · see citing works
Jia, J., Li, B., Sun, Z., Yu, F., Wang, X., & Wang, X. (2010) · Behavioral Neuroscience · doi:10.1037/a0018931 · Cited by 50 · see citing works
Kim, S., Kim, S.-T., Doo, A.-R., Park, J.-Y., Moon, W., Chae, Y., Yin, C. S., Lee, H., & Park, H. (2011) · International Journal of Neuroscience · doi:10.3109/00207454.2011.591515 · Cited by 50 · see citing works
Guo, H.-D., Tian, J.-X., Zhu, J., Li, L., Sun, K., Shao, S.-J., & Cui, G.-H. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/393569 · Cited by 49 · see citing works
Acupuncture plus Herbal Medicine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Zhou, S., Dong, L., He, Y., & Xiao, H. (2017) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x17500732 · Cited by 49 · see citing works
Cheng, C. Y., Lin, J. G., Su, S.-Y., Tang, N.-Y., Kao, S. T., & Hsieh, C. L. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-92 · Cited by 48 · see citing works
Self-citationHistory and Mechanism for Treatment of Intracerebral Hemorrhage with Scalp Acupuncture
Liu, Z., Guan, L., Wang, Y., Xie, C., Lin, X., & Zheng, G. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/895032 · Cited by 48 · see citing works
Electro-acupuncture stimulation improves motor disorders in Parkinsonian rats
Jia, J., Sun, Z., Li, B., Pan, Y., Wang, H., Wang, X., Yu, F., Liu, L., Zhang, L., & Wang, X. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.06.024 · Cited by 48 · see citing works
Oh, J.-Y., Kim, Y.-K., Kim, S.-N., Lee, B., Jang, J.-H., Kwon, S., & Park, H.-J. (2018) · Scientific Reports · doi:10.1038/s41598-018-30337-5 · Cited by 48 · see citing works
Kim, S.-T., Moon, W., Chae, Y., Kim, Y., Lee, H., & Park, H. (2009) · The Journal of Physiological Sciences · doi:10.1007/s12576-009-0061-7 · Cited by 47 · see citing works
Kim, M.-W., Chung, Y. C., Jung, H. C., Park, M., Han, Y., Chung, Y., Maeng, L.-S., Park, S., Lim, J., Im, W., et al. (2012) · Acupuncture in Medicine · doi:10.1136/acupmed-2011-010126 · Cited by 47 · see citing works
Xing, Y., Yang, S., Wang, M., Dong, F., Feng, Y.-S., & Zhang, F. (2018) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1142-y · Cited by 47 · see citing works
Liu, J., Wang, Q., Yang, S., Huang, J., Feng, X., Peng, J., Lin, Z., Liu, W., Tao, J., & Chen, L. (2018) · Medical Science Monitor · doi:10.12659/msm.908473 · Cited by 47 · see citing works
Cheng, C.-Y., Lin, J., Tang, N.-Y., Kao, S.-T., & Hsieh, C. (2015) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-015-0752-y · Cited by 46 · see citing works
Self-citationLv, E., Deng, J., Yu, Y.-P., Wang, Y., Gong, X., Jia, J., & Wang, X. (2015) · Free Radical Research · doi:10.3109/10715762.2015.1067696 · Cited by 45 · see citing works
Zou, R., Wu, Z., & Cui, S.-Y. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3672 · Cited by 45 · see citing works
Aβ25–35 Suppresses Mitochondrial Biogenesis in Primary Hippocampal Neurons
Dong, W., Wang, F., Guo, W.-Q., Zheng, X., Chen, Y., Zhang, W., & Shi, H. (2015) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-015-0222-6 · Cited by 44 · see citing works
Brain areas involved in the acupuncture treatment of AD model rats: a PET study
Lu, Y., Huang, Y., Tang, C., Shan, B., Cui, S., Yang, J., Chen, J., Lin, R., Xiao, H., Qu, S., et al. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-178 · Cited by 44 · see citing works
Wei, H., Yao, X., Yang, L., Wang, S., Guo, F., Zhou, H., Marsicano, G., Wang, Q., & Xiong, L. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8524-5 · Cited by 43 · see citing works
Sun, N., Zou, X., Shi, J., Liu, X., Li, L., & Zhao, L. (2005) · Brain Research · doi:10.1016/j.brainres.2005.09.060 · Cited by 43 · see citing works
Jiang, J. H., Gao, K., Zhou, Y., Xu, A., Shi, S., Liu, G., & Li, Z. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/142129 · Cited by 43 · see citing works
Wang, S. J., Omori, N., Li, F., Jin, G., Zhang, W. R., Hamakawa, Y., Sato, K., Nagano, I., Shoji, M., & Abe, K. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00866-2 · Cited by 41 · see citing works
Hwang, I. K., Chung, J. Y., Yoo, D. Y., Yi, S. S., Youn, H. Y., Seong, J. K., & Yoon, Y. S. (2010) · Journal of Veterinary Medical Science · doi:10.1292/jvms.09-0527 · Cited by 41 · see citing works
Wang, F., Zhong, H., Li, X., Ye, P., Kinden, R., Liang, W., Li, X., Shi, M., Liu, L., Wang, Q., et al. (2014) · Molecular Neurobiology · doi:10.1007/s12035-013-8609-1 · Cited by 41 · see citing works
Electroacupuncture Upregulates SIRT1-Dependent PGC-1α Expression in SAMP8 Mice
Dong, W., Quo, W., Wang, F., Li, C., Xie, Y., Zheng, X., & Shi, H. (2015) · Medical Science Monitor · doi:10.12659/msm.894864 · Cited by 40 · see citing works
Deng, J., Lv, E., Yang, J., Gong, X., Zhang, W., Liang, X., Wang, J., Jia, J., & Wang, X. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0302-z · Cited by 39 · see citing works
Yun, Y.-C., Jang, D., Yoon, S.-B., Kim, D., Choi, D.-H., Kwon, O. S., Lee, Y., & Youn, D.-H. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/7181637 · Cited by 39 · see citing works
Zhao, L., Zhou, C., Li, L., Liu, J., Shi, H., Kan, B., Li, Z., Li, Y., Han, J., & Yu, J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0054-5 · Cited by 38 · see citing works
Liu, H., Chen, L., Zhang, Z., Geng, G., Chen, W., Dong, H., Chen, L., Zhan, S., & Li, T. (2017) · Acupuncture in Medicine · doi:10.1136/acupmed-2016-011342 · Cited by 38 · see citing works
Electroacupuncture improves cognitive deficits associated with AMPK activation in SAMP8 mice
Dong, W., Guo, W.-Q., Zheng, X., Wang, F., Chen, Y., Zhang, W., & Shi, H. (2014) · Metabolic Brain Disease · doi:10.1007/s11011-014-9641-1 · Cited by 37 · see citing works
Choi, Y., Yeo, S., Hong, Y., & Lim, S. (2010) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-010-9629-2 · Cited by 37 · see citing works
Decision making of the p53 network: Death by integration
Li, Z., Ni, M., Li, J., Zhang, Y., Ouyang, Q., & Tang, C. (2010) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2010.11.041 · Cited by 37 · see citing works
Antidepressant-like effects of acupuncture involved the ERK signaling pathway in rats
Zhang, X., Song, Y., Bao, T., Yu, M., Xu, M., Guo, Y., Wang, Y., Zhang, C., & Zhao, B. (2016) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-016-1356-x · Cited by 37 · see citing works
Li, W., Zhu, Y. H., Saud, S. M., Guo, Q., Xi, S., Jia, B., Jiao, S., Yang, X., Lü, J., Song, S., et al. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.01.060 · Cited by 37 · see citing works
Ding, X., Yu, J., Yu, T., Fu, Y., & Han, J. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.01.067 · Cited by 36 · see citing works
YANG, S., Yuan, Y., Jiao, S., Luo, Q., & Yu, J. (2016) · Biomedical Reports · doi:10.3892/br.2016.658 · Cited by 36 · see citing works
Yang, R., Huang, Z., & Cheng, J.-S. (2000) · Acupuncture & Electro-Therapeutics Research · doi:10.3727/036012900816356145 · Cited by 36 · see citing works
Wang, Y., Jiang, H., Meng, H., Lü, J., Li, J., Zhang, X., Yang, X., Zhao, B., Sun, Y., & Bao, T. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.07.021 · Cited by 36 · see citing works
Wang, Y., Jiang, H., Meng, H., Li, J., Yang, X., Zhao, B., Sun, Y., & Bao, T. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/1676808 · Cited by 36 · see citing works
Lin, Y., & Hsieh, C. (2014) · Mediators of Inflammation · doi:10.1155/2014/493480 · Cited by 35 · see citing works
Self-citationAcupuncture for Vascular Dementia: A Pragmatic Randomized Clinical Trial
Shi, G., Li, Q., Yang, B.-F., Liu, Y., Guan, L.-P., Wu, M., Wang, L., & Liu, C. (2015) · The Scientific World JOURNAL · doi:10.1155/2015/161439 · Cited by 35 · see citing works
Role of AC-cAMP-PKA Cascade in Antidepressant Action of Electroacupuncture Treatment in Rats
Liu, J.-H., Wu, Z., Sun, J. H., Jiang, L., Jiang, S., & Fu, W. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/932414 · Cited by 35 · see citing works
Sperk, G., Wieselthaler, A., Pirker, S., Tasan, R. O., Strasser, S. S., Drexel, M., Pifl, C., Marschalek, J., Ortler, M., Trinka, E., et al. (2011) · Hippocampus · doi:10.1002/hipo.20923 · Cited by 34 · see citing works
Scalp acupuncture attenuates neurological deficits in a rat model of hemorrhagic stroke
Liu, H., Sun, X., Zou, W., Leng, M.-T., Zhang, B., Kang, X., He, T., & Wang, H. (2017) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2017.03.014 · Cited by 34 · see citing works
Liu, Y., Yue, N., Zhu, X., Han, Q.-Q., Liu, Q., Yu, J. M., & Wu, G.-C. (2013) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-13-288 · Cited by 33 · see citing works
Guo, J., Liu, J., Fu, W., Ma, W., Xu, Z., Yuan, M., Song, J., & Hu, J. (2007) · Brain Research · doi:10.1016/j.brainres.2007.10.017 · Cited by 33 · see citing works
Molecular Imaging in Traditional Chinese Medicine Therapy for Neurological Diseases
Wang, Z., Wan, H., Li, J., Zhang, H., & Tian, M. (2013) · BioMed Research International · doi:10.1155/2013/608430 · Cited by 33 · see citing works
Zhang, Y., Lin, R., Tao, J., Wu, Y., Chen, B., Yu, K., Chen, J., Li, X., & Chen, L. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3428 · Cited by 33 · see citing works
Duan, D.-M., Tu, Y., Liu, P., & Jiao, S. (2016) · Neural Regeneration Research · doi:10.4103/1673-5374.193238 · Cited by 33 · see citing works
Zhu, Y., Deng, L., Tang, H., Gao, X., Wang, Y., Guo, K., Kong, J., & Yang, C. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.04.003 · Cited by 32 · see citing works
Pak, M. E., Jung, D. H., Lee, H. J., Shin, M., Kim, S.-Y., Shin, Y. B., Yun, Y.-J., Shin, H. K., & Choi, B. T. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.11.014 · Cited by 32 · see citing works
Effects of electroacupuncture on apoptotic pathways in a rat model of focal cerebral ischemia
Kim, Y. R., Kim, H. N., Jang, J. Y., Park, C., Lee, J., Shin, H. K., Choi, Y. H., & Choi, B. T. (2013) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2013.1511 · Cited by 31 · see citing works
p53 signalling mediates acupuncture-induced neuroprotection in Parkinson's disease
Park, J.-Y., Choi, H. G., Baek, S., Jang, J., Lee, A., Jeon, S., Kim, J., & Park, H. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.03.105 · Cited by 31 · see citing works
Yang, E. J., Cai, M., & Lee, J. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9610-7 · Cited by 31 · see citing works
The Effectiveness and Safety of Acupuncture for Patients with Chronic Urticaria: A Systematic Review
Yao, Q., Li, S., Liu, X., Qin, Z., & Liu, Z. (2016) · BioMed Research International · doi:10.1155/2016/5191729 · Cited by 31 · see citing works
Functional protection of learning and memory abilities in rats with vascular dementia
Yang, H.-Y., Shi, O., Jin, Y.-J., Henrich-Noack, P., Qiao, H., Cai, C.-Q., Tao, H., & Tian, X. (2014) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-140409 · Cited by 30 · see citing works
Liao, E.-T., Tang, N.-Y., Lin, Y., & Hsieh, C. L. (2017) · Scientific Reports · doi:10.1038/s41598-017-00601-1 · Cited by 30 · see citing works
Self-citationStriatal-enriched Tyrosine Protein Phosphatase (STEP) in the Mechanisms of Depressive Disorders
Kulikova, E. A., & Kulikov, A. V. (2017) · Current Protein and Peptide Science · doi:10.2174/1389203718666170710121532 · Cited by 30 · see citing works
Xu, J., She, Y., Su, N., Zhang, R.-X., Lao, L., & Xu, S. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/650729 · Cited by 28 · see citing works
Duan, D. M., Dong, X., Tu, Y., & Liu, P. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.05.054 · Cited by 28 · see citing works
Yang, X., Guo, Z., Lü, J., Zhao, B., Fei, Y., Li, J., Jiang, H., Sun, L., Wang, Y., Sun, Y., et al. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/2357653 · Cited by 27 · see citing works
Liao, H.-Y., Sun, M.-F., Lin, J., Chang, S., & Lee, Y. (2015) · Acupuncture in Medicine · doi:10.1136/acupmed-2014-010724 · Cited by 26 · see citing works
Wu, C., Wang, J., Li, C., Zhou, G., Xu, X., Zhang, X., & Xiao, L. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/414965 · Cited by 26 · see citing works
Zhu, Y., Zeng, Y., Wang, X., & Ye, X. (2012) · Neurological Sciences · doi:10.1007/s10072-012-1209-4 · Cited by 25 · see citing works
Huang, J., Ye, X., You, Y., Liu, W., Gao, Y., YANG, S., Peng, J., Hong, Z., Tao, J., & Chen, L. (2014) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2014.1702 · Cited by 25 · see citing works
Kim, S.-T., Doo, A.-R., Kim, S., Kim, S., Kim, Y. Y., Kim, J.-H., Lee, H., Yin, C. S., & Park, H. (2012) · The Journal of Physiological Sciences · doi:10.1007/s12576-012-0216-9 · Cited by 25 · see citing works
Choi, Y., Yeo, S., Hong, Y., Kim, S., & Lim, S. (2011) · Gene · doi:10.1016/j.gene.2011.03.006 · Cited by 25 · see citing works
Yeo, S., Choi, Y., Hong, Y., & Lim, S. (2012) · Gene · doi:10.1016/j.gene.2012.12.002 · Cited by 24 · see citing works
Piperlonguminine is neuroprotective in experimental rat stroke
Yang, T., Sun, S., Wang, T., Tong, X., Jun-hui, B., Wang, Y., & Sun, Z. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.09.016 · Cited by 24 · see citing works
The role of acupuncture in managing overactive bladder; a review of the literature
Forde, J., Jaffe, E. M., Stone, B. V., Te, A. E., Espinosa, G., & Chughtai, B. I. (2016) · International Urogynecology Journal · doi:10.1007/s00192-015-2935-y · Cited by 24 · see citing works
Liang, J., Lu, J. G., Cui, S.-F., Wang, J.-R., & Tu, Y. (2012) · PubMed · Cited by 21 · see citing works
Li, H., Li, Y., Chen, Z., Zhang, X., Zheng, X.-W., Yang, W.-T., Chen, S., & Zheng, G. (2016) · Neural Plasticity · doi:10.1155/2016/7308261 · Cited by 21 · see citing works
Zhou, G., Xiao, L., Zhang, X., Wu, C., Li, C., & Xu, X. (2017) · Neural Regeneration Research · doi:10.4103/1673-5374.202944 · Cited by 21 · see citing works
Lin, D., Wu, Q., Lin, X., Borlongan, C. V., He, Z., Tan, J., Cao, C., & Zhou, S. (2015) · PubMed · Cited by 20 · see citing works
Lu, K.-W., Yang, J., Hsieh, C., Hsu, Y.-C., & Lin, Y. (2016) · Acupuncture in Medicine · doi:10.1136/acupmed-2015-011041 · Cited by 20 · see citing works
Self-citationLiao, E.-T., Lin, Y., Huang, C.-P., Tang, N.-Y., & Hsieh, C. (2018) · BioMed Research International · doi:10.1155/2018/5407256 · Cited by 20 · see citing works
Self-citationKahan, B. D. (2011) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2011.579898 · Cited by 19 · see citing works
Li, H., Li, J.-H., Liu, A., Ye, M.-Y., & Zheng, G. (2014) · Acupuncture in Medicine · doi:10.1136/acupmed-2014-010546 · Cited by 19 · see citing works
Zhou, H.-J., Tang, T., Zhong, J., Luo, J., Cui, H., Zhang, Q., Zhou, J., & Zhang, Q. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-127 · Cited by 17 · see citing works
Rice, A. D., Patterson, K., Wakefield, L. B., Reed, E. D., Breder, K., Wurn, B. F., King, R., III, & Wurn, L. J. (2015) · PubMed · Cited by 17 · see citing works
Electroacupuncture Reduces Aβ Production and BACE1 Expression in SAMP8 Mice
Dong, W., Wang, F., Chen, Y., Zheng, X.-H., Xie, Y.-C., Guo, W., & Shi, H. (2015) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2015.00148 · Cited by 16 · see citing works
Fan, L., Zhao, C., Fu, W., Xu, N., Liu, J., Lü, A., Li, Z., Su, S.-Y., Wu, T., & Ou, A. (2016) · Journal of Acupuncture and Meridian Studies · doi:10.1016/j.jams.2016.04.002 · Cited by 16 · see citing works
Lü, F., Zhu, H., Xie, J., Zhou, H., Chen, Y., & Hu, J. (2008) · PubMed · Cited by 14 · see citing works
Li, Z., Zheng, X., Li, P., Itoua, E. S. R., Moukassa, D., & Andely, F. N. (2017) · Medical Science Monitor · doi:10.12659/msm.897689 · Cited by 14 · see citing works
Guo, J., Liu, J., Fu, W., Ma, W., Xu, Z., Yuan, M., Zhou, X., & Hu, J. (2008) · The Journal of Physiological Sciences · doi:10.2170/physiolsci.rp010508 · Cited by 13 · see citing works
Xu, T., Xu, N., Yang, Z., Wan, Y., Wu, Q., & Huang, K. (2015) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-015-1972-1 · Cited by 13 · see citing works
Fang, J., Zhu, S.-X., Zhang, Y., Wang, F., & Zhu, Q. (2013) · PubMed · Cited by 13 · see citing works
Xu, T., Li, W., Liang, Y.-Q., Yang, Z., Liu, J., Wang, Y., & Su, N. (2014) · PubMed · Cited by 13 · see citing works
Efficacy and safety of penetration acupuncture on head for acute intracerebral hemorrhage
Wang, H.-Q., Bao, C.-L., Jiao, Z., & Dong, G.-R. (2016) · Medicine · doi:10.1097/md.0000000000005562 · Cited by 13 · see citing works
Acupuncture Upregulates G Protein Coupled Activity in Samp8 Mice
Benhua, L., Zhao, L., Zhang, X., Kan, B., Liu, Y., Jia, Y., Han, J., & Yu, J. (2017) · Acupuncture in Medicine · doi:10.1136/acupmed-2016-011139 · Cited by 12 · see citing works
Wu, C., Li, C., Zhou, G., Yang, L., Guimei, J., Chen, J., Li, Q., Zhan, Z., Xu, X., & Zhang, X. (2017) · Acupuncture in Medicine · doi:10.1136/acupmed-2016-011121 · Cited by 12 · see citing works
Dai, W., Li, W., & Lu, J. (2010) · PubMed · Cited by 11 · see citing works
Wang, B. E., Yang, R., & Cheng, J.-S. (1994) · Acupuncture & Electro-Therapeutics Research · doi:10.3727/036012994816357277 · Cited by 11 · see citing works
Yang, R., Huang, Z., & Cheng, J.-S. (1999) · Acupuncture & Electro-Therapeutics Research · doi:10.3727/036012999816356327 · Cited by 11 · see citing works
Hu, L., Liang, J., Jin, S.-Y., Han, Y.-J., Lu, J. L., & Tu, Y. (2013) · PubMed · Cited by 10 · see citing works
Liu, Z., Niu, W.-M., Yang, X.-B., Niu, X.-M., & Wang, Y. (2011) · PubMed · Cited by 10 · see citing works
Li, X.-Y., Xu, L., Liu, C., Huang, L., & Zhu, X. (2016) · PubMed · Cited by 9 · see citing works
Li, T., Zhao, J.-G., Tian, G.-J., Zhang, L., & Liu, S. (2006) · PubMed · Cited by 8 · see citing works
Wang, S., Fang, J., Ma, J., Wang, Y., Zeng, X., Zhou, D., & Sun, G. (2013) · PubMed · Cited by 8 · see citing works
Yang, F., Ma, Y., Ang, W.-P., Chen, H., Du, W.-D., Wu, S.-B., Lü, L., & Zhang, D.-Q. (2014) · PubMed · Cited by 8 · see citing works
Lin, Y., Liu, Q., Chen, C., Chen, W., Xiao, H., Yang, Q.-Y., & Tian, H.-M. (2017) · PubMed · doi:10.11817/j.issn.1672-7347.2017.04.003 · Cited by 8 · see citing works
[Scalp acupuncture for epileptiform discharges of children with cerebral palsy].
Li, S., Liu, Z., Zhao, W., Jin, B., Li, N., & Luo, G. (2017) · PubMed · doi:10.13703/j.0255-2930.2017.03.012 · Cited by 7 · see citing works
Ji, Q., Li, Z., Tang, Y., Mo, Y., Yao, H., & Saiyin, C.-K. (2013) · PubMed · Cited by 6 · see citing works
[Effect of electroacupuncture on hippocampal NO-cGMP signaling pathway in depression rats].
Han, Y.-J., Li, W.-X., Jia, B., Shi, Y., & Tu, Y. (2009) · PubMed · Cited by 6 · see citing works
Wang, H., Wang, L., Liang, F.-X., Liu, J., Li, J., Ji-dong, L., Fu, Y., Chen, Q., Hao, Q., & Wu, S. (2016) · PubMed · Cited by 6 · see citing works
Onat, F. (2016) · Northern Clinics of Istanbul · doi:10.14744/nci.2016.16056 · Cited by 6 · see citing works
Tian, W.-J., Huang, L.-N., Wang, R., An, J., & Zhang, M. (2015) · PubMed · Cited by 5 · see citing works
Chen, S., Ding, M., & Dai, K.-Y. (2011) · PubMed · Cited by 5 · see citing works
Tu, Q., Liang, Y., Ma, J., Wang, S., Shen, F., & Wang, Y. (2015) · PubMed · Cited by 5 · see citing works
Wang, S., Ma, J., Gong, Y., Wang, Y., Zeng, X., Liang, Y., & Sun, G. (2014) · PubMed · Cited by 5 · see citing works
Shao, R.-H., Jin, S.-Y., Lü, J., Hu, L., & Tu, Y. (2015) · PubMed · Cited by 5 · see citing works
[C-fos expression in rat brain during seizure and electroacupuncture].
Wang, B. E., & Cheng, J. S. (1994) · PubMed · Cited by 4 · see citing works
Yang, F., Ang, W.-P., Shen, D.-K., Liu, X., Yang, Y., & Ma, Y. (2013) · PubMed · Cited by 4 · see citing works
Zhang, G., Zou, W., & Liu, F. (2012) · PubMed · Cited by 3 · see citing works
Guo, Y., Ke Cheng, X. U., Bao, W.-Y., Wang, Y., Zhang, X., Xu, M., Yu, M., Zhang, C., Zhao, B., Wu, J., et al. (2016) · PubMed · Cited by 2 · see citing works
Zhang, H., Fan, Y., Xu, W., Shen, D.-K., Chen, H., Wu, S.-B., Ang, W.-P., Song, X.-G., & Xie, M.-Y. (2017) · PubMed · Cited by 2 · see citing works
Xie, C., Luo, Y., Pang, Y., Gao, X., Li, M., Wen, H.-Q., & Ruifang, C. (2014) · PubMed · Cited by 1 · see citing works
Liu, T., Yu, J., & Han, J. (2008) · PubMed · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Zhu, L., Shi, Y., Liu, L., Wang, H., Shen, P., & Yang, H. (2020) · Cell Cycle · doi:10.1080/15384101.2020.1769301 · Cited by 91 · see citing works
Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury
Chen, C.-H., & Hsieh, C. (2020) · Antioxidants · doi:10.3390/antiox9030248 · Cited by 59 · see citing works
Self-citationWei, T.-H., & Hsieh, C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21134693 · Cited by 56 · see citing works
Self-citationLyu, Y., Meng, Z., Hu, Y., Jiang, B., Yang, J., Chen, Y., Zhou, J., Li, M., & Wang, H. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1394932 · Cited by 42 · see citing works
Wu, Z., Cai, Z., Shi, H., Huang, X., Cai, M., Yuan, K., Huang, P., Shi, G., Yan, T., & Li, Z. (2022) · Aging · doi:10.18632/aging.204030 · Cited by 37 · see citing works
Acupuncture improved lipid metabolism by regulating intestinal absorption in mice
Han, J., Guo, X., Meng, X., Zhang, J., Yamaguchi, R., Motoo, Y., & Yamada, S. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i34.5118 · Cited by 36 · see citing works
Swain, M., Soman, S. K., Tapia, K., Dagda, R. Y., & Dagda, R. K. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15945 · Cited by 39 · see citing works
FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential
Zhang, L., & Wang, H. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.08.013 · Cited by 34 · see citing works
Huang, T.-I., & Hsieh, C. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/6624976 · Cited by 31 · see citing works
Self-citationExosomes Immunity Strategy: A Novel Approach for Ameliorating Intervertebral Disc Degeneration
Li, W., Zhang, S., Wang, D., Zhang, H., Shi, Q., Zhang, Y., Wang, M., Ding, Z., Xu, S., Gao, B., et al. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.822149 · Cited by 29 · see citing works
Wie, H.-S., & Kim, S. (2025) · Journal of Chinese Integrative Medicine · doi:10.1016/j.joim.2025.02.002 · Cited by 27 · see citing works
Yang, X., Wang, J., Jia, X.-T., Yang, Y., Fang, Y., Ying, X., Li, H., Zhang, M., Wei, J., & Pan, Y. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877241313223 · Cited by 22 · see citing works
Ning, B., Wang, Z., He, J., Wu, Q., Deng, Q., Yang, Q., Gao, J., Fu, W., Deng, Y., Wu, B., et al. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148609 · Cited by 21 · see citing works
Wang, J., Xu, X., Jia, W., Zhao, D., Boczek, T., Gao, Q., Wang, Q., Fu, Y., He, M., Shi, R., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/4635054 · Cited by 21 · see citing works
Shi, J., Zhang, X., Chen, J., Shen, R.-S., Cui, H., & Wu, H. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1275860 · Cited by 20 · see citing works
Zhang, B., Wang, G.-R., Ning, W., Liu, J., Yang, S., Shen, Y. H., Wang, Y., Zhao, M., Li, L., & Chen, Y. (2020) · Neural Plasticity · doi:10.1155/2020/8840675 · Cited by 19 · see citing works
Chen, L., Jiang, H., Bao, T., Wang, Y., Meng, H., Sun, Y., Liu, P., Quan, S., Li, W., Qi, S., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.903004 · Cited by 19 · see citing works
Wang, J., Wang, J., Wang, Y., Chai, Y., Li, H., Miao, D., Liu, H., Li, J., & Bao, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098119 · Cited by 18 · see citing works
Machine Learning in Neuroimaging: A New Approach to Understand Acupuncture for Neuroplasticity
Yin, T., Ma, P., Tian, Z., Xie, K., He, Z., Sun, R., & Zeng, F. (2020) · Neural Plasticity · doi:10.1155/2020/8871712 · Cited by 17 · see citing works
Xiao, X., Zhang, J., Jin, Y., Wang, Y., & Zhang, Q. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/5865697 · Cited by 15 · see citing works
Cheng, H., Yuan, Y., Hu, J., Chen, L., Yuan, M., Du, H., Xu, Z., & Qiu, Z. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122901 · Cited by 15 · see citing works
Crosstalk between Acupuncture and NF‐κB in Inflammatory Diseases
Luo, D., Li, L., Huang, Q., Zhang, H.-M., Yu, Z., Hu, M., Li, J., Liang, F.-X., & Chen, R. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/7924985 · Cited by 14 · see citing works
Liu, Y., Yan, Z., Ren, Y., Wang, W., Ke, Y., Wang, Y., & Qi, R. (2022) · Acupuncture in Medicine · doi:10.1177/09645284221136878 · Cited by 14 · see citing works
Li, X., Qi, S., Wang, Y., Jiang, H., Li, Y., Zhao, B., Zhang, T., Sun, Y., Gao, X., Quan, S., et al. (2021) · The Anatomical Record · doi:10.1002/ar.24740 · Cited by 14 · see citing works
Efficacy of Acupuncture in Postoperative Pain-Relieving: A Systematic Review and Meta-Analysis
Liu, J., Liu, J., Liu, J., & Zhang, X. (2025) · Pain Management Nursing · doi:10.1016/j.pmn.2024.12.014 · Cited by 7 · see citing works
Tuina plus acupuncture for post-stroke depression
Meng, M., Hu, G., Yang, K., Wang, H., Han, Y., Pan, T. J., Lou, H., Zhang, Y., Wang, Y., & Cong, D. (2021) · Medicine · doi:10.1097/md.0000000000026013 · Cited by 6 · see citing works
Liu, D., Chen, B., Li, T., Zheng, L., Li, J., Du, W., Wang, M., & Huang, Y. (2022) · Journal of Pain Research · doi:10.2147/jpr.s383291 · Cited by 5 · see citing works
Jin, H., Huang, R., Zhu, L., Liu, M., Zhao, N., Zhang, H., & Lin, Y. (2024) · The Journal of Physiological Sciences · doi:10.1186/s12576-024-00941-4 · Cited by 4 · see citing works
Jiang, H., Chen, L., Li, Y., Gao, X., Yang, X., Zhao, B., Li, Y., Wang, Y., Yu, X. L., Zhang, X., et al. (2023) · Neuroscience Letters · doi:10.1016/j.neulet.2023.137056 · Cited by 3 · see citing works
Proteomic profiling of small extracellular vesicles from bovine nucleus pulposus cells
Samanta, A., Yoo, M., Koh, J., Lufkin, S., Lufkin, T., & Kraus, P. (2025) · PLoS ONE · doi:10.1371/journal.pone.0324179 · Cited by 3 · see citing works
Yang, Y., Hu, S., Jiang, H., Zhang, J., & Tang, C. (2019) · Medicine · doi:10.1097/md.0000000000017557 · Cited by 3 · see citing works
Chen, W. J., Livneh, H., Hsu, C.-H., Hu, Y.-T., Lai, N., Guo, H., & Tsai, T. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2020.601606 · Cited by 3 · see citing works
Zhang, Q.-A., Luo, W.-S., Li, J., Zhang, Q.-W., Guo, Q., Chen, J., & Liang, Z. (2024) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s483940 · Cited by 2 · see citing works
Tao and Golden Ratio: A Scientific View of Contemporary Acupunctural Principles through Geometry
Inchauspe, A. Á., & Arakaki, E. (2023) · Chinese Medicine · doi:10.4236/cm.2023.143006 · Cited by 2 · see citing works
Ritonga, M. Z., Lisnanti, E. F., Lokapirnasari, W. P., Hidanah, S., Rehman, S., Amrullah, M. F., Anggriawan, R., Abuzahra, M., Hasan, D. I., Shehzad, A., et al. (2025) · Veterinary World · doi:10.14202/vetworld.2025.2367-2376 · Cited by 1 · see citing works
Bibliometric and Meta-analysis of Acupuncture Treatment for Autism
Liao, Y., Shi, Y., Zeng, S., Chen, Y., Yin, M., Yang, H., & Chen, X. (2026) · Innovations in Acupuncture and Medicine · doi:10.1186/s44424-025-00042-y · Cited by 1 · see citing works
Lei, S., Wang, Z., Ouyang, D., Huang, T., Huang, K., Li, X., & Huang, Z.-X. (2026) · iScience · doi:10.1016/j.isci.2026.114915 · Cited by 1 · see citing works
Chang, T.-J., Yeh, M., Yeh, A. L., & Kuo, A. L. (2024) · Research Square · doi:10.21203/rs.3.rs-3974242/v1 · Cited by 1 · see citing works
Samanta, A., Yoo, M., Koh, J., Lufkin, T., & Kraus, P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.12.628054 · Cited by 1 · see citing works
Wu, Z., Huang, X., Cai, M., Huang, P., & Guan, Z. (2021) · Research Square · doi:10.21203/rs.3.rs-958945/v1
Akupunktur in der Psychiatrie – Chancen und Grenzen
Musil, R., Hofer, E.-M., & Colling, C. (2021) · Zeitschrift für Komplementärmedizin · doi:10.1055/a-1663-5248
BI-D1870 Causes the Rats’ Learning and Memory Acquisition Ability Impairment
Zhang, C., He, K., Li, C., & Shang, Y. (2023) · Journal of Biosciences and Medicines · doi:10.4236/jbm.2023.111009
Low-dose Esketamine promotes brain protection via the ERK/Nrf2 pathway in vascular dementia ratsPreprint
Shi, J., Guo, M., Yu, X., Zhang, H., Li, X., & Gan, J. (2023) · Research Square · doi:10.21203/rs.3.rs-3599975/v1
Non-Pharmacologic Alternatives in the Management of Alzheimer’s Disease
Yutan, E., Faller, E. M., & Tiwari, P. K. (2023) · German Journal of Pharmaceuticals and Biomaterials · doi:10.5530/gjpb.2023.3.7
Liu, Y., Yixilamu, Jin, G., Feng, M., Chunhua, & Dawa, D. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e40443
Low-Dose Esketamine Promotes Brain Protection Via the Erk/Nrf2 Pathway in Vascular Dementia RatsPreprint
Wang, C., Yu, X., Zheng, Z., Wang, Y., Guo, M., & Gan, J. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.5026732
Hu, D., Sun, W., Wang, W., Chen, Z., Wang, H., & Zhai, S. (2024) · Research Square · doi:10.21203/rs.3.rs-5656048/v1
Zhou, F., Wang, Z., Xiong, K., Fu, X., Jiang, H., Zhang, M., Wang, Q., & Wang, Y. (2025) · Acupuncture in Medicine · doi:10.1177/09645284251314187
Research Progress on the Mechanism of Acupuncture Treatment for Sciatica
Xu, H., Wei, W., Ke, T., Jin, J., Wu, X., & Lu, C. (2025) · Journal of Contemporary Medical Practice · doi:10.53469/jcmp.2025.07(02).24
Wu, Z., Jin, H., Shuai, B., Zhang, X., Wang, S., Chen, L., & Huang, B. (2025) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.2025.j102
Huang, C., Gao, S., Zheng, X., Song, X., Wu, J., Liao, K., Li, J., Lin, Y., Li, C., Lu, Y., et al. (2026) · MedComm · doi:10.1002/mco2.70595
Han, Y. J., Park, G., Kim, G.-Y., Jang, J. E., Sung, W.-S., Kim, K.-H., & Lee, S.-D. (2026) · Journal of Acupuncture Research · doi:10.13045/jar.25.0058
Deepa, Y., Saravanan, V., Anbukalaiselvan, M., Divakaran, K., Jayamaruthi, N. S., & Mooventhan, A. (2026) · International Journal of Health & Allied Sciences · doi:10.4103/ijhas.ijhas_44_25
Yu, D., Wang, J., Xie, M., Lu, Y., & Wang, H. (2026) · Biomedicines · doi:10.3390/biomedicines14081727
Chiara, P., Wijaya, S., Dewi, F., Viventius, Y., & Djaali, W. (2026) · Medical Acupuncture · doi:10.1177/19336586261489072
- Authors
- Lai, H.-C., Chang, Q.-Y., & Hsieh, C.-L.
- Affiliations
- China Medical University Hospital (TW)
- Department of Family Medicine, Lin Shin Hospital, Taichung 408, Taiwan
- China Medical University (TW)
- Corresponding author
- Hsieh, Ching-Liang
- Venue
- Evidence-based Complementary and Alternative Medicine
- Publisher
- Wiley
- Published
- 2019-07-11
- Volume
- 2019
- Pages
- 1-37
- ISSN
- 1741-427X (ISSN-L)
- 1741-4288
- PMC
- PMC6657648
- OpenAlex
- W2958707998
- Cited by
- 55
- References
- 194
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 10 · 2023: 8 · 2022: 5 · 2021: 7 · 2020: 9 · 2019: 1
- FWCI
- 1.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Evidence-based Complementary and Alternative Medicine (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Ministry of Education (CMRC-CENTER-0, DMR-108-176)
- China Medical University Hospital (CMRC-CENTER-0, DMR-108-176)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Acupuncture Treatment Research Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Studies
- Health Sciences › Medicine › Pharmacology › Healthcare and Venom Research
- Keywords
- acupuncture, signaling pathways, neurological disorders, brain-derived neurotrophic factor, p38 MAPK, PI3K/Akt, CREB, NF-κB, Bcl-2/Bax, synaptic plasticity, neuroprotection, apoptosis inhibition, anti-inflammation, antioxidant activity, blood-brain barrier, stroke, epilepsy, depression, Alzheimer's disease, Parkinson's disease, ischemic brain injury
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review