The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps
Open accessAbstract
Coronavirus disease 2019 (COVID-19) is a virus-induced respiratory disease that may progress to acute respiratory distress syndrome (ARDS) and is triggered by immunopathological mechanisms that cause excessive inflammation and leukocyte dysfunction. Neutrophils play a critical function in the clearance of bacteria with specific mechanisms to combat viruses. The aim of this review is to highlight the current advances in the pathways of neutrophilic inflammation against viral infection over the past ten years, focusing on the production of neutrophil extracellular traps (NETs) and its impact on severe lung diseases, such as COVID-19. We focused on studies regarding hyperinflammation, cytokine storms, neutrophil function, and viral infections. We discuss how the neutrophil’s role could influence COVID-19 symptoms in the interaction between hyperinflammation (overproduction of NETs and cytokines) and the clearance function of neutrophils to eliminate the viral infection. We also propose a more in-depth investigation into the neutrophil response mechanism targeting NETosis in the different phases of COVID-19.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures

Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Findings from this study and others indicate that inflammatory responses serve as a primary driver of the progressive and persistent pathophysiologic features of severe COVID-19 (43–46).”
From Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19 (2021) · cites this paper as [43]
In the citing paper
“NETs have been shown to promote tissue factor activation and fibrin deposition, consistent with our observations, suggesting a role for NETs in intra-alveolar thrombosis and the formation or organization of platelet-rich clots (43, 45).”
From Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19 (2021) · cites this paper as [43]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Clinical characteristics of coronavirus disease 2019 in China
Guan, W.-J., Ni, Z.-Y., Hu, Y., Liang, W.-H., Ou, C.-Q., He, J.-X., Liu, L., Shan, H., Lei, C.-L., Hui, D. S. C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2002032 · Cited by 30,246
Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415
Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., et al. (2020) · JAMA · doi:10.1001/jama.2020.1585 · Cited by 20,148
La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
Martínez González, M. (2020) · DSPACE System - Metalibrary (University of the Coast) · Cited by 18,463
Neutrophil Extracellular Traps Kill Bacteria
Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D. S., Weinrauch, Y., & Zychlinsky, A. (2004) · Science · doi:10.1126/science.1092385 · Cited by 10,268
COVID-19: consider cytokine storm syndromes and immunosuppression
Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S., & Manson, J. J. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30628-0 · Cited by 9,664
Ruan, Q., Yang, K., Wang, W., Jiang, L., & Song, J. (2020) · Intensive Care Medicine · doi:10.1007/s00134-020-05991-x · Cited by 4,898
Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China
Qin, C., Zhou, L., Hu, Z., Zhang, S., Yang, S., Tao, Y., Xie, C., Ma, K., Shang, K., Wang, W., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa248 · Cited by 4,775
Novel cell death program leads to neutrophil extracellular traps
Fuchs, T. A., Abed, U., Goosmann, C., Hurwitz, R., Schulze, I., Wahn, V., Weinrauch, Y., Brinkmann, V., & Zychlinsky, A. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200606027 · Cited by 3,197
Cited by
Sorted by citations
Items 101–200 of 235
Reduction in Absolute Neutrophil Counts in Patient on Clozapine Infected with COVID-19
Ramli, F. F., Ali, A., Hashim, S. A. S., Kamisah, Y., & Ibrahim, N. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182111289 · Cited by 8
ADAM17 inhibition prevents neutrophilia and lung injury in a mouse model of Covid-19Preprint
Lartey, N. L., Valle‐Reyes, S., Vargas‐Robles, H., Jiménez-Camacho, K. E., Guerrero-Fonseca, I. M., Castellanos-Martínez, R., Montoya‐García, A., García‐Cordero, J., Cedillo‐Barrón, L., Nava, P., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.10.439288 · Cited by 8
Yang, L., Liu, J., Hu, Y., Cong, C., CHEN, Y., & Zhou, Q. (2024) · Biocell · doi:10.32604/biocell.2023.045862 · Cited by 7
Liao, Y., Liu, Y., Li, D., Luo, S., Huang, Y., Wu, J., Su, J., Yang, Y., Wu, J., Zhu, Z., et al. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02095-1 · Cited by 6
Plasma essential fatty acid on hospital admission is a marker of COVID-19 disease severity
Mazurak, V. C., Rivas‐Serna, I. M., Parsons, S. R., Monirujjaman, M., Maybank, K. E., Woo, S. K., Rewa, O. G., Cave, A., Richard, C., & Clandinin, M. T. (2023) · Scientific Reports · doi:10.1038/s41598-023-46247-0 · Cited by 7
Luo, L., Gao, P., Yang, C., & Yu, S. (2024) · Scientific Reports · doi:10.1038/s41598-024-78498-w · Cited by 7
Chong, Z.-Z., & Souayah, N. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210506161543 · Cited by 7
Wu, T.-H., Hsieh, S., Li, T.-H., Lu, C., Liao, H., Shen, C., Li, K., Wu, C.-H., Kuo, Y., Tsai, C., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10040773 · Cited by 7
Berghäll, E., Hultström, M., Frithiof, R., Lipcsey, M., & Hahn‐Strömberg, V. (2022) · Biomedicines · doi:10.3390/biomedicines10050934 · Cited by 7
Mediu, R., Rama, A., & Puca, E. (2022) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.16310 · Cited by 8
Singh, V., Singh, N. L., Pradhan, A., Kumar, Y., & Bhatnagar, S. (2023) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2023.107004 · Cited by 7
Nayak, S. S., Naidu, A., Sajitha Lulu, S., Sundararajan, V., & Selvaraj, G. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13040664 · Cited by 6
Is there a role for growth hormone replacement in adults to control acute and post-acute COVID-19?
Venugopal, N. K., Armstrong, P. A., Wright, T. J., Randolph, K. M., Batson, R. D., Yuen, K. C. J., Masel, B. E., Sheffield‐Moore, M., Pyles, R. B., & Urban, R. J. (2023) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2023.101842 · Cited by 6
Xu, X., Zhu, X., Wang, H., Liu, X., Yang, C., Liu, L., Chen, T., Cai, L., & Zhu, H. (2024) · Infection and Drug Resistance · doi:10.2147/idr.s450318 · Cited by 6
de Oliveira, V. L. S., Queiroz‐Junior, C. M., Hoorelbeke, D., Santos, F. R. D. S., Chaves, I. D. M., Teixeira, M. M., Russo, R. C., Proost, P., Costa, V. V., Struyf, S., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1378591 · Cited by 6
Hussein, A. A., AL–Mammori, R. T. O., Hassan, F. G., Al-Khafaje, M. E., Saeedi, K. R. H. A., & Al-Charrakh, A. H. (2024) · Medical Journal of Babylon · doi:10.4103/mjbl.mjbl_1060_23 · Cited by 6
El-Kady, A. M., Aldakheel, F. M., Allemailem, K. S., Almatroudi, A., Alharbi, R. D., Al-Hamed, H. A., Alsulami, M. N., Alshehri, W. A., El-Ashram, S. A., Kreys, E., et al. (2022) · International Journal of General Medicine · doi:10.2147/ijgm.s374090 · Cited by 6
Mycotic infection as a risk factor for COVID-19: A meta-analysis
Liu, A., Li, Z., Su, G., Li, Y., Zhang, Y., Liang, J., Cheng, X., Wang, X., Li, Y., & Ye, F. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.943234 · Cited by 6
Jami, G., Ataee, M., Esmaeili, V., Chamani, S., Rezaei, A., & Naghizadeh, A. (2023) · PubMed Central · Cited by 6
Sendo, F., Yoshitake, H., & Araki, Y. (2022) · Microbiology and Immunology · doi:10.1111/1348-0421.12978 · Cited by 5
Prognostic Significance of the Coagulation and Complement Systems in Critical COVID-19 Infection
Ray, A., Winter, K. A. K., Naik, D. S. L., & Okorie, C. (2023) · Prague Medical Report · doi:10.14712/23362936.2023.7 · Cited by 6
Liu, D.-H., Li, F., Yang, R., Wu, Z., Meng, X., Li, S., Li, W., Kang, J., Wang, D., Wang, R., et al. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02141-y · Cited by 6
Abeysuriya, V., Seneviratne, S. L., Silva, A. P. D., Mowjood, R., Mowjood, S., de Silva, T., de Mel, P., de Mel, C., Chandrasena, L. G., Wijesinha, R. S., et al. (2021) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1093/trstmh/trab182 · Cited by 5
Azghar, A., Bensalah, M., Berhili, A., Slaoui, M., Mouhoub, B., Mezgueldi, I. E., Nassiri, O., Malki, J. E., Maleb, A., & Seddik, R. (2022) · Journal of International Medical Research · doi:10.1177/03000605221109381 · Cited by 5
Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
Hansen, N. (2023) · Antibodies · doi:10.3390/antib12030049 · Cited by 5
Machine Learning-Based Prediction of COVID-19 Prognosis Using Clinical and Hematologic Data
Kamel, F. O., Magadmi, R. M., Qutub, S., Badawi, M. A., Badawi, M., Madani, T. A., Alhothali, A., Abozinadah, E., Bakhshwin, D., Jamal, M., et al. (2023) · Cureus · doi:10.7759/cureus.50212 · Cited by 5
RetractedElevated glycohemoglobin is linked to critical illness in COVID-19: a retrospective analysis
Windham, S., Wilson, M. P., Fling, C., Sheneman, D. W., Wand, T., Babcock, L. R., MaWhinney, S., & Erlandson, K. M. (2021) · Therapeutic Advances in Infectious Disease · doi:10.1177/20499361211027390 · Cited by 5
Hematologic Involvement as a Predictor of Mortality in COVID-19 Patients in a Safety Net Hospital
Gonzalez-Mosquera, L. F., Gomez-Paz, S., Lam, E. H., Cardenas-Maldonado, D. D. D., Fogel, J., Adi, V., & Rubinstein, S. (2022) · Kansas Journal of Medicine · doi:10.17161/kjm.vol15.15699 · Cited by 5
Hypertonic Solution in Severe COVID-19 Patient: A Potential Adjuvant Therapy
Gennari-Felipe, M., Borges, L., Dermargos, A., Weimann, E., Curi, R., Pithon‐Curi, T. C., & Hatanaka, E. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.917008 · Cited by 4
Self-citationRelationship of Circulatory Markers of NETosis with COVID-19 Severity: A Prospective Cohort Study
Kumar, A., Kumar, N., Banerjee, A., Kumar, A., Kumar, A., & Sinha, C. (2025) · Indian Journal of Critical Care Medicine · doi:10.5005/jp-journals-10071-25103 · Cited by 4
Gunasekara, S., Selvan, M. T., Murphy, C. L., Shatnawi, S., Cowan, S. R., More, S., Ritchey, J. W., Miller, C., & Rudd, J. M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251810054 · Cited by 4
Li, P., Zhang, C., Wang, M., Zhang, X., Zhang, Y., Tang, K., Hu, H., Jia, X., Zhuang, R., Jin, B., et al. (2022) · Viral Immunology · doi:10.1089/vim.2022.0007 · Cited by 4
COVID-19: Energy, Protein Folding & Prion Disease
Thorp, K. E., Thorp, J. A., Thorp, E. M., BS, F. W., Thorp, M. M., JD MACP. Law Firm of Margery M. Thorp, P., Walker, P. R., & BSME, M. (2022) · The Gazette of Medical Sciences · doi:10.46766/thegms.neuro.22083101 · Cited by 3
Carretta, M. D., Creutzburg, P., Borquez, K., Quiroga, J., Alarcón, P., Rivera, A., & Burgos, R. A. (2022) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2022.104562 · Cited by 5
Leukocyte metabolism in obese type 2 diabetic individuals associated with COVID-19 severity
Lobato, T. B., Gennari-Felipe, M., Pauferro, J. R. B., Correa, I. S., Santos, B. F., Dias, B. B., Borges, J. C. D. O., dos Santos, C. S., Santos, E. S. D. S., de Araújo, M. J. L., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1037469 · Cited by 4
Self-citationLu, T., Man, Q., Yu, X., Xia, S., Lu, L., Jiang, S., & Xiong, L. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1157892 · Cited by 4
Multisystem Inflammatory Syndrome in Children: A Comprehensive Review Over the Past Five Years
Shyong, O., AlFakhri, N., Bates, S. V., Carroll, R. W., Gallagher, K., Huang, L., Madhavan, V. L., Murphy, S. A., Okrzesik, S. A., Yager, P. H., et al. (2025) · Journal of Intensive Care Medicine · doi:10.1177/08850666251320558 · Cited by 6
Twindemic of Coronavirus Disease (COVID-19) and Cardiometabolic Diseases
Rao, G. H. R. (2021) · International Journal of Biomedicine · doi:10.21103/article11(2)_ra1 · Cited by 4
Трухан, Д. И., Филиппович, С. А., & Trukhan, L. Y. (2022) · Consilium Medicum · doi:10.26442/20751753.2022.5.201755 · Cited by 4
Liang, Z., Zheng, X., Wang, Y., Chu, K., & Gao, Y. (2023) · Functional & Integrative Genomics · doi:10.1007/s10142-023-01091-3 · Cited by 4
Li, C., Wu, K., Yang, R., Liao, M., Li, J., Zhu, Q., Zhang, J., & Zhang, X. (2024) · Scientific Reports · doi:10.1038/s41598-024-59117-0 · Cited by 4
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Li, J., Wang, Y., Fan, X., Xu, M., Li, J., Tan, W., Zhang, J., & Li, H. (2026) · Advanced Science · doi:10.1002/advs.202520383 · Cited by 4
Asaba, C. N., Gwanyama, B. N., Ayuk, H. S., Odo, T. I., Bitazar, R., Noumi, T., Labonté, P., & Bukong, T. N. (2026) · Cells · doi:10.3390/cells15070580 · Cited by 4
Айтбаев, К. А., Murkamilov, I. T., Fomin, V. V., Kudaibergenova, I., & Yusupov, F. A. (2021) · Бюллетень Восточно-Сибирского научного центра Сибирского отделения Российской академии медицинских наук · doi:10.29413/abs.2021-6.4.6 · Cited by 3
The Role of Neutrophil Extracellular Traps in the Ocular System
Li, Y., Xie, L., Song, W., Huang, M., Cheng, Y., Chen, S., Gao, Y. Z., & Yan, X. (2022) · Current Eye Research · doi:10.1080/02713683.2022.2079141 · Cited by 3
Lu, Y., Wang, C., Wang, Y., Chen, Y., Zhao, L., & Li, Y. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1320933 · Cited by 3
Wang, Y., Bai, C., Hou, K., Zhang, Z., Guo, M. S., Wang, X., Yang, F., & Liu, X. (2025) · Advanced Science · doi:10.1002/advs.202504690 · Cited by 4
Insights into Innate Immune Response Against SARS-CoV-2 Infection
Huţanu, A., Georgescu, A. M., Andrejkovits, Á. V., Au, W. W., & Dobreanu, M. (2021) · Revista română de medicină de laborator · doi:10.2478/rrlm-2021-0022 · Cited by 3
Can the immune system be targeted to treat COVID-19?
Abdelhafeez, S., & Doherty, D. G. (2021) · European Respiratory Society eBooks · doi:10.1183/2312508x.10024120 · Cited by 3
Teplyuk, N. P., Grabovskaya, O. V., Kusraeva, D. T., Grekova, E. V., Koriakin, D. A., & Kostenko, A. Y. (2022) · Russian Journal of Skin and Venereal Diseases · doi:10.17816/dv111864 · Cited by 3
Changes in the Cytokine Profile in Patients During COVID-19 Infection
Ivanov, N., Mihailova, S., Bilyukov, R., Popov, C., Kundurzhiev, T., & Naumova, E. J. (2023) · Acta Medica Bulgarica · doi:10.2478/amb-2023-0036 · Cited by 3
Borges, R., Bandeira, C. C. S., Zerbinati, R. M., Palmieri, M., Schwab, G., Braz‐Silva, P. H., Lindoso, J. Â. L., & Martinho, H. D. S. (2024) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2024.124320 · Cited by 3
Identification of High Death Risk Coronavirus Disease-19 Patients using Blood Tests
Hosseingholi, E. Z., Maddahi, S., Jabbari, S., & Molavi, G. (2022) · Advanced Biomedical Research · doi:10.4103/abr.abr_178_21 · Cited by 3
Pardiño-Vega, M. A., & Herrera-González, N. E. (2023) · Exploration of Immunology · doi:10.37349/ei.2023.00115 · Cited by 2
Wang, L., Hu, Q., Yang, Y., Chen, M., Yang, C., & Han, B. (2023) · Annals of Medicine · doi:10.1080/07853890.2023.2274510 · Cited by 2
Differential white blood cell count predicting severity and mortality in patients with COVID-19
Sai, S. S., Vijeth, K. V., & Hemalatha, A. S. (2021) · The Journal of Association of Chest Physicians · doi:10.4103/jacp.jacp_3_21 · Cited by 2
Kelly, E. J., Oliver, M. A., Carney, B. C., Kolachana, S., Moffatt, L. T., & Shupp, J. W. (2023) · Surgical Infections · doi:10.1089/sur.2023.156 · Cited by 2
Mei, J., Wang, S., Zhao, Y., Xu, T., Luo, Y., & Xiong, L. (2024) · Ibrain · doi:10.1002/ibra.12179 · Cited by 2
Hachimi, A., El‐Mansoury, B., & Merzouki, M. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107360 · Cited by 2
Hematologic and Immunologic Overlap Between COVID-19 and Idiopathic Pulmonary Fibrosis
Mara, G., Nini, G., Frent, S., & Cotoraci, C. A. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14155229 · Cited by 3
COVID-19 during Early Phase of Autologous Stem Cell Transplantation
Milczarek, S., Baumert, B., Sobuś, A., Wilk-Milczarek, E., Sommerfeld, K., Osękowska, B., Borowiecka, E., Paczkowska, E., Łanocha, A. A., Poncyliusz, W., et al. (2021) · Medicina · doi:10.3390/medicina57070724 · Cited by 2
The role of IL-6, ferritin, and coagulopathy in COVID-19 clinical progression
Harahap, A. T., Irawan, C., Susilo, A., Harimurti, K., Gathmyr, D., Shatri, H., Lubis, A. M., Nainggolan, L., & Abdullah, M. (2022) · F1000Research · doi:10.12688/f1000research.125115.1 · Cited by 3
Impact of Various Hematological and Biochemical Parameters in Severe and Nonsevere COVID-19 Patients
Banerjee, A., Banerjee, J., Mazumdar, M., & Phukan, J. P. (2022) · Mustansiriya Medical Journal · doi:10.4103/mj.mj_52_22 · Cited by 2
Correlation between NLR and PLR with the Severity of COVID-19 Inpatients
Andiani, F., Herawati, R., & Triyani, Y. (2023) · INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY · doi:10.24293/ijcpml.v29i1.1924 · Cited by 2
Evaluation of Thyroid Function Tests in Children With Covid-19Preprint
Ayrancı, İ., Çatlı, G., Manyas, H., Tüz, A. E., Çolak, A., Yılmaz, D., DUMAN, J. G. Y., & Dündar, B. N. (2022) · Research Square · doi:10.21203/rs.3.rs-1433666/v1 · Cited by 2
Major Inflammatory Markers and Their Significance in Predicting Severity of COVID-19 Disease Pattern
Aedh, A. I., Hajri, A., Alshahrani, A., Adam, M., Dahab, A., Babker, A. M. A., & Mohamed, H. (2021) · International Journal of Biomedicine · doi:10.21103/article11(4)_oa13 · Cited by 1
Akrom, A., Hidayati, T., Kurniawan, N. U., & Saputri, G. Z. (2022) · International Journal of Public Health Science (IJPHS) · doi:10.11591/ijphs.v11i3.21683 · Cited by 1
Research Progress of Neutrophil to Lymphocyte Ratio and Viral Infectious Diseases
李, 佳. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.133655 · Cited by 1
Gunasekara, S., Shatnawi, S., More, S., Ludwig, B., Narayanan, S. S., Selvan, M. T., Miller, C., & Rudd, J. M. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1547918 · Cited by 1
Novel Molecular Subtyping Revealed Molecular Pathways That Contribute to the Pathogenesis of Rosacea
Hu, X., Liu, L., Huang, Y., Zhang, Y., Zhao, H., Zhao, H., Guo, Y., Xie, H., Deng, Z., Chen, M., et al. (2025) · The Journal of Dermatology · doi:10.1111/1346-8138.17798 · Cited by 1
Yang, H., Wang, W., Huang, J., Yan, Y., Wang, S., Shen, Q., Li, J., & Jin, T. (2025) · Die Naturwissenschaften · doi:10.1007/s00114-025-02016-9 · Cited by 1
Wang, L., Zhang, Y., Bao, L., Guo, Y., Hai, Q., Wu, J., Wang, T., Sun, G., & Liang, X. (2025) · Metabolomics · doi:10.1007/s11306-025-02337-w · Cited by 1
Aji, N., Jia, B., Zheng, C., Li, M., Song, J., Pan, T., Zhang, C., Chao, Y., Chen, C., 杜春玲, et al. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.116958 · Cited by 1
da Silva, D. A. A., Andrade-Silva, L. E., Desidério, C. S., Farnesi-de-Assunção, T. S., Oliveira, A. C. D. M., Trevisan, R. O., Obata, M. M. S., Helmo, F. R., Barbosa, L. M., Costa-Madeira, J. C., et al. (2022) · Research Society and Development · doi:10.33448/rsd-v11i4.27439 · Cited by 1
Subpopulation composition of peripheral blood lymphocytes in COVID-19
Svirshchevskaya, E. V., Konovalova, M. V., Sadykov, V. F., Pyregov, P. A. V., & Полтавцева, Р. А. (2022) · Medical Immunology (Russia) · doi:10.15789/1563-0625-sco-2552 · Cited by 1
Ahsan, T., Fatema, K., Shoily, S. S., Haidar, Z., & Sajib, A. A. (2023) · Journal of Bangladesh Academy of Sciences · doi:10.3329/jbas.v47i1.65144 · Cited by 1
Wikanningtyas, T. A., F, F. S. A., & Maulana, A. (2023) · eJournal Kedokteran Indonesia · doi:10.23886/ejki.10.233.246-50 · Cited by 1
The role of IL-6, ferritin, and coagulopathy in Covid-19 clinical progression
Harahap, A. T., Irawan, C., Susilo, A., Harimurti, K., Gathmyr, D., Shatri, H., Lubis, A. M., Nainggolan, L., & Abdullah, M. (2023) · F1000Research · doi:10.12688/f1000research.125115.2 · Cited by 1
Risamasu, J. D., Suparyatmo, J., & Kurniati, A. (2023) · INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY · doi:10.24293/ijcpml.v30i1.2054 · Cited by 1
Dziedzic, K., Pruc, M., Kilic, M., Ah, R., Yıldırım, M., Szarpak, Ł., Safiejko, K., Khamisy‐Farah, R., Chirico, F., & Bragazzi, N. L. (2023) · Disaster and Emergency Medicine Journal · doi:10.5603/demj.98191 · Cited by 1
The Long-Acting Serine Protease Inhibitor mPEG-SPA-MDSPI16 Alleviates LPS-Induced Acute Lung Injury
Chen, J., Zhou, X., Dai, N., Liu, X., Liu, S., Zhang, H., Kong, L., & Ma, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084567 · Cited by 1
The black cumin seeds oil with Curcuma xanthorrhiza extract preparation increases IFN-γ expression
Hidayati, T., Sun, H. S., & Akrom, A. (2023) · Bali Medical Journal · doi:10.15562/bmj.v12i3.3781 · Cited by 1
Phagocytic activity of leukocytes in patients with COVID-19
Костинов, М. П., Gaynitdinova, V. V., Osiptsov, V. N., Bisheva, I. V., Skhodova, S. A., Khromova, E. A., Baranova, I. A., Kryukova, N. O., Sokolova, E., & Чучалин, А. Г. (2024) · PULMONOLOGIYA · doi:10.18093/0869-0189-2024-34-6-846-856 · Cited by 1
Костинов, М. П., Свитич, О. А., Чучалин, А. Г., Gajnitdinova, V., Bisheva, I. V., Skhodova, S. A., Osiptsov, V. N., Tatevosov, V. R., Kryukova, N., Khrapunova, I., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0324987 · Cited by 1
Lopes, L. R. (2021) · Brazilian Journal of Microbiology · doi:10.1007/s42770-021-00497-0 · Cited by 1
Alkeridy, W. A., Alanazy, M. H., Alamri, N. K., Alqahtani, A. M., Alhazzani, A. A., & Muayqil, T. A. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.737328 · Cited by 1
Alterações leucocitárias em pacientes com COVID-19 observadas em extensão de sangue periférico
Coradi, C., & Vieira, S. L. V. (2021) · Research Society and Development · doi:10.33448/rsd-v10i11.19838 · Cited by 1
Padmaprakash, K. V., Ashta, K. K., Raman, N., Vardhan, V., Thareja, S., Muthukrishnan, J., Rajmohan, K., Dubey, S., Nauhwaar, D., Kumar, A., et al. (2021) · Journal of Marine Medical Society · doi:10.4103/jmms.jmms_3_21 · Cited by 1
Aquilizan, A. R. R., Elynn, L. G., & Luna, I. (2021) · Acta Scientific Paediatrics · doi:10.31080/aspe.2021.04.0455 · Cited by 1
Ambarwati, N. S. S., Desmiaty, Y., Ahmad, I., Samsul, E., & Ramadhan, A. M. (2023) · Journal of Applied Biology & Biotechnology · doi:10.7324/jabb.2023.11503 · Cited by 1
Evidence for the utility of cfDNA plasma concentrations to predict disease severity in COVID-19Preprint
Hoeter, K., Neuberger, E. W. I., Fischer, S., Herbst, M., Juškevičiūtė, E., Rossmann, H., Sprinzl, M. F., Simon, P. D., Bodenstein, M., & Schäfer, M. K. E. (2021) · medRxiv · doi:10.1101/2021.04.29.21256291
Overview of SARS-CoV-2 Infection and Its Potential Reactions
Mortaz, E., & Dezfuli, N. K. (2021) · Trends in Medical Sciences · doi:10.5812/tms.115161
Immune System in COVID-19: Is It Temporarily Defeated While Conquering?
Wynn, A. A., & Mya, N. K. (2022) · Borneo Journal of Medical Sciences (BJMS) · doi:10.51200/bjms.vi.3210
Parashar, B., Pathak, M., & Ahmad, A. (2021) · International Journal of Health Sciences · doi:10.53730/ijhs.v5ns2.5865
A map of neutrophil granules by proteomics
Freitas, G. A. D. M. (2022) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.46.2022.tde-06092022-125307
Szewczyk-Dąbrowska, A., Banasik, M., Dąbrowska, K., Kujawa, K., Bombała, W., Sebastian, A., Matera-Witkiewicz, A., Krupińska, M., Grata-Borkowska, U. T., Sokołowski, J., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12030878
Bailo, G., Rodríguez, F. M., Carabajal-Miotti, C. L., de Frattari, S. G. R., Vargas, A. H., González-Silva, N. E., & Novák, I. (2023) · European Journal of Clinical Medicine · doi:10.24018/clinicmed.2023.4.1.240
Evarnitskaya, N. R., & Олегович, Я. О. (2023) · Infectious diseases News Opinions Training · doi:10.33029/2305-3496-2023-12-1-90-96
Shanbhag, V., Chaudhuri, S., Arjun, N. R., Pandey, A. K., Vishwas, P., & Sharma, M. (2023) · Sri Lankan Journal of Anaesthesiology · doi:10.4038/slja.v31i1.8905
Barbullushi, A., Kristo, A., Davidhi, A., & Kullolli, I. (2023) · International Journal of Biomedicine · doi:10.21103/article13(2)_cr5
Metadata
- Authors
- Borges, L., Pithon-Curi, T. C., Curi, R., & Hatanaka, E.
- Affiliations
- Universidade Cruzeiro do Sul (BR)
- Instituto de Ciências da Atividade Física e Esportes (ICAFE), Universidade Cruzeiro do Sul, São Paulo, SP, Brazil
- Instituto Butantan (BR)
- Corresponding author
- Borges, Leandro
- Venue
- Mediators of Inflammation
- Publisher
- Wiley
- Published
- 2020-12-02
- Volume
- 2020
- Pages
- 1-7
- ISSN
- 0962-9351 (ISSN-L)
- 1466-1861
- PMC
- PMC7732408
- OpenAlex
- W3109283769
- Cited by
- 235
- References
- 64
- Citations by year
- 2026: 8 · 2025: 17 · 2024: 36 · 2023: 59 · 2022: 66 · 2021: 49
- FWCI
- 4.25
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Mediators of Inflammation (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (88882.314890/2013-01)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (88882.314890/2013-01)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (88882.314890/2013-01)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
- Keywords
- COVID-19 pandemic, neutrophils, neutrophil extracellular traps, NETosis, hyperinflammation, cytokine storm, acute respiratory distress syndrome, neutrophil dysfunction, lung disease
- MeSH terms
- Host Microbial Interactions, Cytokine Release Syndrome, COVID-19, SARS-CoV-2, Humans, Immunity, Innate, Inflammation, Lung, Neutrophils, Respiratory Distress Syndrome, Models, Immunological, Inflammation Mediators, Pandemics, Extracellular Traps
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review