Therapeutic Role of Mango Peels in Management of Dyslipidemia and Oxidative Stress in Obese Females
Open accessAbstract
Obesity is a chronic metabolic and noncommunicable disease that affects 50% of world population. Reactive oxygen species and oxidative stress are interconnected with the obesity and several metabolic disorders, gaining the attention of scientific community to combat this problem naturally. Among various fruits, mango as a yellow fruit is rich in polyphenols, carotenoids, terpenes, and flavonoids that act as antioxidants to protect against free radicals produced in the body. The present study was performed to explore in vivo antioxidant potential of mango peels against dyslipidemia and oxidative stress in overweight subjects. The female volunteers (n = 31) between 25 and 45 years of age having a body mass index (BMI) of 25.0‐29.9 (overweight) were included in this study, while participants with complications as diabetes, hypertension, cardiovascular, and liver diseases were excluded. The treatment group consumed 1 g mango peel powder for 84 days. The subjects were analyzed for biochemical analysis, antioxidant status, and anthropometric measurements at baseline and end of the study period. Further, at the end of study, the safety evaluation tests were also performed. The results showed that upon consumption of mango peel powder, low‐density lipoproteins (LDL), cholesterol, triglyceride, urea, and creatinine levels were decreased and high‐density lipoprotein (HDL) level was increased (P ≤ 0.05), while thiobarbituric acid reactive substances (TBARS) showed increased antioxidant status (P ≤ 0.05) which suggests that mango peels have a strong management potential against oxidative stress and dyslipidemia in obese subjects.
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Mango peels have antioxidant activity.
“They also found important antioxidant activity, suggesting that mango peels have a considerable potential to control oxidative stress and dyslipidemia in obese individuals.”
From Mangifera indica L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review (2023) · cites this paper as [37]
Mango peel powder can improve lipid profiles in obese women.
“According to Arshad et al. [37], the use of mango peel powder can improve lipid profiles in obese women.”
From Mangifera indica L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review (2023) · cites this paper as [37]
Arshad et al. included only women.
“and the inclusion of only women”
From Mangifera indica L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review (2023) · cites this paper as [37]
Arshad et al. had a small sample size.
“there are important limitations: the small sample size”
From Mangifera indica L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review (2023) · cites this paper as [37]
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- Authors
- Arshad, F., Umbreen, H., Aslam, I., Hameed, A., Aftab, K., Al-Qahtani, W. H., Aslam, N., & Noreen, R.
- Affiliations
- Government College University, Faisalabad (PK)
- University of Management and Technology (PK)
- King Saud University (SA)
- Corresponding author
- Noreen, Razia
- Venue
- BioMed Research International
- Publisher
- Wiley
- Published
- 2021-01
- Volume
- 2021
- Issue
- 1
- Pages
- 3094571-3094571
- ISSN
- 1110-7243 (ISSN-L)
- 2314-6133
- 2314-6141
- PMC
- PMC8557052
- OpenAlex
- W3208260346
- Cited by
- 20
- References
- 45
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 1 · 2023: 3 · 2022: 3
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- BioMed Research International (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- King Saud University (RSP-2020/293)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Mangiferin and Mango Extracts
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Surgery › Natural Products and Biological Research
- Keywords
- mango peel, dyslipidemia, oxidative stress, obesity, overweight women, antioxidant activity, lipid profile, LDL cholesterol, HDL cholesterol, triglycerides, TBARS, dietary polyphenols, functional foods
- MeSH terms
- Adult, Antioxidants, Carotenoids, Female, Flavonoids, Fruit, Humans, Obesity, Plant Extracts, Triglycerides, Body Mass Index, Reactive Oxygen Species, Oxidative Stress, Mangifera, Dyslipidemias, Overweight
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