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Cited by 763

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing

Open access
Deng, Liling, Du, Chenzhen, Song, Peiyang, Chen, Tianyi, Rui, Shunli, Armstrong, David G., Deng, Wuquan·2021·Oxidative Medicine and Cellular Longevity

Abstract

Foot ulcers are one of the most common and severe complication of diabetes mellitus with significant resultant morbidity and mortality. Multiple factors impair wound healing include skin injury, diabetic neuropathy, ischemia, infection, inadequate glycemic control, poor nutritional status, and severe morbidity. It is currently believed that oxidative stress plays a vital role in diabetic wound healing. An imbalance of free radicals and antioxidants in the body results in overproduction of reactive oxygen species which lead to cell, tissue damage, and delayed wound healing. Therefore, decreasing ROS levels through antioxidative systems may reduce oxidative stress‐induced damage to improve healing. In this context, we provide an update on the role of oxidative stress and antioxidants in diabetic wound healing through following four perspectives. We then discuss several therapeutic strategies especially dietary bioactive compounds by targeting oxidative stress to improve wounds healing.

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Metadata

Authors
Deng, L., Du, C., Song, P., Chen, T., Rui, S., Armstrong, D. G., & Deng, W.
Venue
Oxidative Medicine and Cellular Longevity
Publisher
Wiley
Published
2021-01
Volume
2021
Issue
1
Pages
8852759-8852759
ISSN
  • 1942-0994 (ISSN-L)
  • 1942-0900
OpenAlex
W3127835035
Cited by
763
References
8
FWCI
39.68
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing. https://app.cochat.ai/papers/10.1155/2021/8852759
The paper
Deng, L., Du, C., Song, P., Chen, T., Rui, S., Armstrong, D. G., & Deng, W. (2021). The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing. Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2021/8852759

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.