The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing
Open accessAbstract
Foot ulcers are one of the most common and severe complication of diabetes mellitus with significant resultant morbidity and mortality. Multiple factors impair wound healing include skin injury, diabetic neuropathy, ischemia, infection, inadequate glycemic control, poor nutritional status, and severe morbidity. It is currently believed that oxidative stress plays a vital role in diabetic wound healing. An imbalance of free radicals and antioxidants in the body results in overproduction of reactive oxygen species which lead to cell, tissue damage, and delayed wound healing. Therefore, decreasing ROS levels through antioxidative systems may reduce oxidative stress‐induced damage to improve healing. In this context, we provide an update on the role of oxidative stress and antioxidants in diabetic wound healing through following four perspectives. We then discuss several therapeutic strategies especially dietary bioactive compounds by targeting oxidative stress to improve wounds healing.
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Citations
Cites
Biochemistry and molecular cell biology of diabetic complications
Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107
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Understanding Diabetic Neuropathy: Focus on Oxidative Stress
Pang, L., Lian, X., Liu, H., Zhang, Y., Li, Q., Cai, Y., Ma, H., & Yu, X. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/9524635 · Cited by 184
Cited by
Anti‐inflammatory hydrogel dressings and skin wound healing
Huang, C., Dong, L., Zhao, B., Lu, Y., Huang, S., Yuan, Z., Luo, G., Xu, Y., & Qian, W. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.1094 · Cited by 445
Bagheri, M., Validi, M., Gholipour, A., Makvandi, P., & Sharifi, E. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10254 · Cited by 268
Pang, Y., Wang, H., Yao, Y., Chen, D., Yang, R., Wang, Z., Yang, J., Li, Y., & Liu, W. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202303095 · Cited by 76
Vitamin C supplementation for diabetes management: A comprehensive narrative review
Mason, S. A., Parker, L., van der Pligt, P., & Wadley, G. D. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.12.003 · Cited by 53
Conceição, M., Gushiken, L. F. S., Aldana-Mejía, J. A., Tanimoto, M. H., Ferreira, M. V. D. S., Alves, A. C. M., Miyashita, M. N., Bastos, J. K., Beserra, F. P., & Pellizzon, C. H. (2022) · Antioxidants · doi:10.3390/antiox11112188 · Cited by 34
Metadata
- Authors
- Deng, L., Du, C., Song, P., Chen, T., Rui, S., Armstrong, D. G., & Deng, W.
- Venue
- Oxidative Medicine and Cellular Longevity
- Publisher
- Wiley
- Published
- 2021-01
- Volume
- 2021
- Issue
- 1
- Pages
- 8852759-8852759
- ISSN
- 1942-0994 (ISSN-L)
- 1942-0900
- OpenAlex
- W3127835035
- Cited by
- 763
- References
- 8
- FWCI
- 39.68
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Deng, L., Du, C., Song, P., Chen, T., Rui, S., Armstrong, D. G., & Deng, W. (2021). The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing. Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2021/8852759
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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