Pathobiology of Alcoholic Pancreatitis

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

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Identification, culture, and characterization of pancreatic stellate cells in rats and humans

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Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture

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Cytotoxic T lymphocytes: all roads lead to death

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The Role of Cytokines in the Pathogenesis of Acute Pancreatitis

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NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis

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Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

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Presence of Nonoxidative Ethanol Metabolism in Human Organs Commonly Damaged by Ethanol Abuse

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Activation of Pancreatic Stellate Cells in Human and Experimental Pancreatic Fibrosis

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Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis.

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Course of alcoholic chronic pancreatitis: A prospective clinicomorphological long-term study

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Calcium-dependent enzyme activation and vacuole formation in the apical granular region of pancreatic acinar cells

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Mitochondrial role in life and death of the cell.

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Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis

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Early NF-κB activation is associated with hormone-induced pancreatitis

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Cigarette smoking accelerates progression of alcoholic chronic pancreatitis

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Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis

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Digestive diseases in the United States: Epidemiology and impact

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The Role of Intracellular Calcium Signaling in Premature Protease Activation and the Onset of Pancreatitis

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Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis

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Fatty Acid Ethyl Esters Cause Pancreatic Calcium Toxicity via Inositol Trisphosphate Receptors and Loss of ATP Synthesis

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Cell Death in Pancreatitis

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The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury

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Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells

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The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis

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The Role of Acetaldehyde in the Actions of Alcohol (Update 2000)

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Incidence, aetiology and mortality rate of acute pancreatitis over 10 years in a defined urban population in Sweden

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NF-κB activation in pancreas induces pancreatic and systemic inflammatory response

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Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide

Pandol, S. J., Periskic, S., Gukovsky, I., Zaninovic, V., Jung, Y., Zong, Y., Solomon, T. E., Gukovskaya, A. S., & Tsukamoto, H. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70465-8 · Cited by 221 · see citing works

Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites

Criddle, D. N., Raraty, M. G. T., Neoptolemos, J. P., Tepikin, A. V., Petersen, O. H., & Sutton, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403431101 · Cited by 217 · see citing works

Chemokine gene expression in rat pancreatic acinar cells is an early event associated with acute pancreatitis

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The Epidemiology of Alcohol-Induced Pancreatitis

Dufour, M. C., & Adamson, M. D. (2003) · Pancreas · doi:10.1097/00006676-200311000-00002 · Cited by 211 · see citing works

Chronic relapsing pancreatitis. A study of twenty-nine cases without associated disease of the biliary or gastro-intestinal tract.

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The Role of Acetaldehyde in the Actions of Alcohol (Update 2000)

Eriksson, C. J. P. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200105051-00005 · Cited by 205 · see citing works

The Source and Role of Oxygen-derived Free Radicals in Three Different Experimental Models

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Chronic Pancreatitis and Pancreatic Cancer

Maisonneuve, P., & Lowenfels, A. B. (2002) · Digestive Diseases · doi:10.1159/000063165 · Cited by 196 · see citing works

Epidemiology of pancreatic diseases in Lüneburg county

Lankisch, P. G., Assmus, C., Maisonneuve, P., & Lowenfels, A. B. (2002) · Pancreatology · doi:10.1159/000064713 · Cited by 194 · see citing works

Ethanol metabolism and transcription factor activation in pancreatic acinar cells in rats

Gukovskaya, A. S., Mouria, M., Gukovsky, I., Reyes, C. N., Kasho, V. N., Faller, L. D., & Pandol, S. J. (2002) · Gastroenterology · doi:10.1053/gast.2002.30302 · Cited by 188 · see citing works

Origin and early evolution of the vertebrates: New insights from advances in molecular biology, anatomy, and palaeontology

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Is an elevated concentration of acinar cytosolic free ionised calcium the trigger for acute pancreatitis?

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Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

Werner, J., Laposata, M., Castillo, C. F.-D., Saghir, M., Iozzo, R. V., Lewandrowski, K. B., & Warshaw, A. L. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70106-9 · Cited by 181 · see citing works

Pancreatitis in Finland between 1970 and 1989.

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CD4+ T cells play an important role in acute experimental pancreatitis in mice

Demols, A., Moine, O. L., Desalle, F., Quertinmont, E., Laethem, J. V., & Deviere, J. M. E. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)70265-4 · Cited by 166 · see citing works

Epidemiology and outcome of acute pancreatitis

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Ethanol and signal transduction in the liver

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Immune cell infiltration and growth-associated protein 43 expression correlate with pain in chronic pancreatitis

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The relationship between inflammatory and serosal connective tissue changes in ileal Crohn's disease: evidence for a possible causative link

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Ethanol and the pancreas

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Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis

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Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity

van Acker, G. J. D., Saluja, A. K., Bhagat, L., Singh, V. P., Song, A. M., & Steer, M. L. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00363.2001 · Cited by 154 · see citing works

Curcumin ameliorates ethanol and nonethanol experimental pancreatitis

Gukovsky, I., Reyes, C. N., Vaquero, E. C., Gukovskaya, A. S., & Pandol, S. J. (2003) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00138.2002 · Cited by 152 · see citing works

Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat

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Cell death pathways in pancreatitis and pancreatic cancer

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Activation of pancreatic acinar cells on isolation from tissue: cytokine upregulation via p38 MAP kinase

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PKC-δ and -ε regulate NF-κB activation induced by cholecystokinin and TNF-α in pancreatic acinar cells

Satoh, A., Gukovskaya, A. S., Nieto, J. M., Cheng, J. H., Gukovsky, I., Reeve, J. R., Shimosegawa, T., & Pandol, S. J. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00087.2004 · Cited by 144 · see citing works

Chronic Alcohol Consumption Accelerates Fibrosis in Response to Cerulein-Induced Pancreatitis in Rats

Deng, X., Wang, L., Elm, M. S., Gabazadeh, D., Diorio, G. J., Eagon, P. K., & Whitcomb, D. C. (2005) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62235-3 · Cited by 130 · see citing works

Angiotensin-converting enzyme inhibitor attenuates pancreatic inflammation and fibrosis in male Wistar Bonn/Kobori rats

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Extracellular Cleavage of E-Cadherin by Leukocyte Elastase During Acute Experimental Pancreatitis in Rats

Mayerle, J. V., Schnekenburger, J., Krüger, B., Kellermann, J., Ruthenbürger, M., Weiß, F. U., Nalli, A., Domschke, W., & Lerch, M. M. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.08.002 · Cited by 121 · see citing works

Recurrent acute pancreatitis: An algorithmic approach to identification and elimination of inciting factors

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Ethanol and Arachidonic Acid Increase α2(I) Collagen Expression in Rat Hepatic Stellate Cells Overexpressing Cytochrome P450 2E1

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Cytotoxic cells are activated in cellular infiltrates of alcoholic chronic pancreatitis

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Macrophage migration inhibitory factor is a critical mediator of severe acute pancreatitis

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Smoking, Coffee, and Pancreatitis

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Protein Content of Precipitates Present in Pancreatic Juice of Alcoholic Subjects and Patients With Chronic Calcifying Pancreatitis

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Alcohol Activates Activator Protein-1 and Mitogen-Activated Protein Kinases in Rat Pancreatic Stellate Cells

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The clinical picture of the sequential development of acute hemorrhagic pancreatitis in the dog.

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Immunohistochemical Characterization of the Pancreatic Cellular Infiltrate in Normal Pancreas, Chronic Pancreatitis and Pancreatic Carcinoma

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Fatty acid ethyl esters toxic non-oxidative metabolites of ethanol and markers of ethanol intake

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CCK stimulates mob-1 expression and NF-κB activation via protein kinase C and intracellular Ca2+

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A mouse model of ethanol dependent pancreatic fibrosis

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Cerulein upregulates ICAM-1 in pancreatic acinar cells, which mediates neutrophil adhesion to these cells

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Pancreatic response to endotoxin after chronic alcohol exposure: switch from apoptosis to necrosis?

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Metabolism of ethanol by rat pancreatic acinar cells

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Associations of alcohol drinking and nutrient intake with chronic pancreatitis: findings from a case-control study in Japan

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Perforin/Fas-Ligand Double Deficiency Is Associated with Macrophage Expansion and Severe Pancreatitis

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Animal Models in Alcoholic Pancreatitis — What Can We Learn?

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Alcohol Metabolism: Role in Toxicity and Carcinogenesis

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The effect of environmental cues on the differentiation of myofibroblasts in peritoneal granulation tissue

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Biological Effects of Disruption of the Tissue‐Type Plasminogen Activator, Urokinase‐Type Plasminogen Activator, and Plasminogen Activator Inhibitor‐1 Genes in Micea

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Nonoxidative metabolism of ethanol in the pancreas; implication in alcoholic pancreatic damage

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Candesartan, an Angiotensin II Receptor Antagonist, Suppresses Pancreatic Inflammation and Fibrosis in Rats

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The role of acetaldehyde in the actions of alcohol

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Ethanol sensitizes NF-κB activation in pancreatic acinar cells through effects on protein kinase C-ε

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Macrophages infiltrating the tissue in chronic pancreatitis express the chemokine receptor CCR5

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Alcohol and the pancreas. I. Clinical associations and histopathology of minimal pancreatic inflammation.

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Development of an animal model of chronic alcohol-induced pancreatitis in the rat

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Carboxylester Lipase Gene Polymorphism as a Risk of Alcohol-induced Pancreatitis

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The Role of Acetaldehyde in the Pathogenesis of Acute Alcoholic Pancreatitis

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Pancreas Recovery Following Cerulein-Induced Pancreatitis Is Impaired in Plasminogen-Deficient Mice

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Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis

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Enhanced urokinase plasminogen activation in chronic pancreatitis suggests a role in its pathogenesis

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Alcohol and the Pancreas

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