Alcohol Use Disorders in Opioid Maintenance Therapy: Prevalence, Clinical Correlates and Treatment
Abstract
Maintenance therapy with methadone or buprenorphine is an established and first-line treatment for opioid dependence. Clinical studies indicate that about a third of patients in opioid maintenance therapy show increased alcohol consumption and alcohol use disorders. Comorbid alcohol use disorders have been identified as a risk factor for clinical outcome and can cause poor physical and mental health, including liver disorders, noncompliance, social deterioration and increased mortality risk. The effects of opioid maintenance therapy on alcohol consumption are controversial and no clear pattern has emerged. Most studies have not found a change in alcohol use after initiation of maintenance therapy. Methadone and buprenorphine appear to carry little risk of liver toxicity, but further research on this topic is required. Recent data indicate that brief intervention strategies may help reduce alcohol intake, but the existing evidence is still limited. This review discusses further clinical implications of alcohol use disorders in opioid dependence.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Most studies have not found a change in comorbid alcohol, cocaine, or benzodiazepine use after initiation of opioid maintenance therapy.
“Since most studies have not found a change in co-morbid alcohol use, cocaine or benzodiazepine use after initiation of opioid maintenance therapy”
From Effects of a trauma-informed mindful recovery program on comorbid pain, anxiety, and substance use during primary care buprenorphine treatment: A proof-of-concept study (2023) · cites this paper as [56]
The Conclusions (p. 6) say that, according to most studies, opioid maintenance therapy does not change alcohol consumption. The paper does not make the same claim about cocaine or benzodiazepine use; it instead reports one study in which benzodiazepine abuse decreased over time (Role of Opioid Maintenance Therapy in Alcohol Consumption, p. 4). (LLM, conf=0.90)
Experimental — accuracy not yet measuredPatients receiving opioid maintenance treatments frequently misuse other drugs, including alcohol, benzodiazepines, cannabis, and gabapentinoids.
“In addition, patients receiving opioid maintenance treatments frequently misuse other drugs, including alcohol, benzodiazepines, cannabis, and gabapentinoids (81, 82).”
From Craving in Opioid Use Disorder: From Neurobiology to Clinical Practice (2019) · cites this paper as [82]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
(2001) · Cited by 5,455 · see citing works
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Mattick, R. P., Breen, C. L., Kimber, J., & Davoli, M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002207.pub4 · Cited by 2,312 · see citing works
Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence
Mattick, R. P., Breen, C., Kimber, J., & Davoli, M. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002209.pub2 · Cited by 1,654 · see citing works
A Meta-Analytic Review of Psychosocial Interventions for Substance Use Disorders
Dutra, L., Stathopoulou, G., Basden, S. L., Leyro, T. M., Powers, M. B., & Otto, M. W. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111851 · Cited by 1,287 · see citing works
Global epidemiology of injecting drug use and HIV among people who inject drugs: a systematic review
Mathers, B. M., Degenhardt, L. J., Phillips, B. W., Wiessing, L. G., Hickman, M., Strathdee, S. A., WODAK, A. D., Panda, S., TYNDALL, M. W., Toufik, A., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61311-2 · Cited by 1,283 · see citing works
Avenevoli, S. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.160 · Cited by 1,149 · see citing works
Degenhardt, L., Bucello, C., Mathers, B., Briegleb, C., Ali, H., Hickman, M., & McLaren, J. (2011) · Addiction · doi:10.1111/j.1360-0443.2010.03140.x · Cited by 856 · see citing works
Opioid antagonists for alcohol dependence
Srisurapanont, M., & Jarusuraisin, N. (2002) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001867 · Cited by 762 · see citing works
Endogenous opioid systems and alcohol addiction
Herz, A. (1997) · Psychopharmacology · doi:10.1007/s002130050169 · Cited by 749 · see citing works
Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior
Spanagel, R. (2009) · Physiological Reviews · doi:10.1152/physrev.00013.2008 · Cited by 636 · see citing works
Connock, M. J., Juarez-Garcia, A., Jowett, S. M., Frew, E. J., Liu, Z., Taylor, R. S., Fry-Smith, A., Day, E., Lintzeris, N., Roberts, T. E., et al. (2007) · Health Technology Assessment · doi:10.3310/hta11090 · Cited by 580 · see citing works
Amato, L., Davoli, M., A.Perucci, C., Ferri, M., Faggiano, F., & P. Mattick, R. (2005) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2005.02.007 · Cited by 567 · see citing works
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Mattick, R. P., Kimber, J., Breen, C., & Davoli, M. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002207.pub3 · Cited by 501 · see citing works
Brief intervention for hazardous and harmful drinking: a manual for use in primary care.
Babor, T. F., & Higgins-Biddle, J. C. (2001) · Cited by 484 · see citing works
Kakko, J., Svanborg, K. D., Kreek, M. J., & Heilig, M. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12600-1 · Cited by 466 · see citing works
Enkephalin may mediate euphoria and drive-reduction reward
Belluzzi, J. D., & Stein, L. (1977) · Nature · doi:10.1038/266556a0 · Cited by 450 · see citing works
(2006) · Neuroscience · doi:10.1016/s0306-4522(05)01473-9 · Cited by 427 · see citing works
Acamprosate for alcohol dependence
Rösner, S., Hackl-Herrwerth, A., Leucht, S., Lehert, P., Vecchi, S., & Soyka, M. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004332.pub2 · Cited by 420 · see citing works
Self-citationFatal heroin 'overdose': a review
Darke, S. G., & ZADOR, D. A. (1996) · Addiction · doi:10.1046/j.1360-0443.1996.911217652.x · Cited by 413 · see citing works
Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram
Carroll, K. M., Nich, C., Ball, S. A., McCance, E. F., & Rounsavile, B. J. (1998) · Addiction · doi:10.1046/j.1360-0443.1998.9357137.x · Cited by 375 · see citing works
Amato, L., Minozzi, S., Davoli, M., & Vecchi, S. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004147.pub4 · Cited by 369 · see citing works
Jørgensen, C. H., Pedersen, B., & Tønnesen, H. (2011) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01523.x · Cited by 366 · see citing works
Role of alcohol in the progression of liver disease caused by hepatitis C virus infection
Ostapowicz, G., Watson, K. J. R., LOCARNINI, S. A., & Desmond, P. V. (1998) · Hepatology · doi:10.1002/hep.510270637 · Cited by 283 · see citing works
Endogenous Opioids and Addiction to Alcohol and other Drugs of Abuse
Gianoulakis, C. (2004) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026043451573 · Cited by 281 · see citing works
Opioid antagonists for alcohol dependence
Srisurapanont, M., & Jarusuraisin, N. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001867.pub2 · Cited by 266 · see citing works
Treatment of patients with substance use disorders, second edition. American Psychiatic Association.
Kleber, H. D., Weiss, R. D., Anton, R. F., George, T. P., Greenfield, S. F., Kosten, T. R., O’Brien, C. P., Rounsaville, B. J., Strain, E. C., Ziedonis, D. M., et al. (2006) · PubMed · Cited by 265 · see citing works
Self-administration of methionine enkephalin into the nucleus accumbens
Goeders, N. E., Lane, J. D., & Smith, J. E. (1984) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(84)90284-3 · Cited by 245 · see citing works
Oswald, L. M., & Wand, G. S. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.02.008 · Cited by 233 · see citing works
Fernández, A. J. C., Marcos, M., Mirón‐Canelo, J., Pastor, I., González‐Sarmiento, R., & Laso, F. J. (2012) · Addiction Biology · doi:10.1111/j.1369-1600.2012.00442.x · Cited by 219 · see citing works
Hubbell, C. L., Czirr, S. A., Hunter, G. A., Beaman, C. M., LeCann, N. C., & Reid, L. D. (1986) · Alcohol · doi:10.1016/0741-8329(86)90070-4 · Cited by 217 · see citing works
A 24-Year Follow-up of California Narcotics Addicts
Hser, Y. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820190079008 · Cited by 208 · see citing works
Patrick, D. M., TYNDALL, M. W., Cornelisse, P., Li, K. K., Sherlock, C. H., Rekart, M. L., Strathdee, S. A., Currie, S. L., Schechter, M. T., & O’Shaughnessy, M. V. (2001) · Europe PMC (PubMed Central) · Cited by 204 · see citing works
Diaz, T., Jarlais, D. C. D., Vlahov, D., Perlis, T. E., Edwards, V., Friedman, S. R., Rockwell, R., Hoover, D. R., Williams, I. T., & Monterroso, E. R. (2001) · American Journal of Public Health · doi:10.2105/ajph.91.1.23 · Cited by 189 · see citing works
Soyka, M., Zingg, C., Koller, G., & Küfner, H. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114570700836x · Cited by 184 · see citing works
Self-citationDrug-related mortality and its impact on adult mortality in eight European countries
Bargagli, A. M., Hickman, M., Davoli, M., Perucci, C. A., Schifano, P., Buster, M. C. A., Brugal, M. T., & Vicente, J. (2005) · European Journal of Public Health · doi:10.1093/eurpub/cki168 · Cited by 170 · see citing works
Orman, J. S., & Keating, G. M. (2009) · Drugs · doi:10.2165/00003495-200969050-00006 · Cited by 138 · see citing works
Jarjour, S., Bai, L., & Gianoulakis, C. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.00924.x · Cited by 130 · see citing works
Causes of death in a cohort treated for opioid dependence between 1985 and 2005
Degenhardt, L., Larney, S., Randall, D., Burns, L., & Hall, W. (2014) · Addiction · doi:10.1111/add.12337 · Cited by 124 · see citing works
Bukten, A., Skurtveit, S. O., Gossop, M., Waal, H., Stangeland, P., Havnes, I. A., & Clausen, T. (2011) · Addiction · doi:10.1111/j.1360-0443.2011.03637.x · Cited by 123 · see citing works
Murrill, C. S., Weeks, H., Castrucci, B. C., Weinstock, H., Bell, B. P., Spruill, C., & GWINN, M. L. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.3.385 · Cited by 122 · see citing works
Saxon, A. J., Ling, W. W., Hillhouse, M. P., Thomas, C., Hasson, A. L., Ang, A., Doraimani, G., Tasissa, G., Lokhnygina, Y. V., Leimberger, J., et al. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.08.002 · Cited by 120 · see citing works
Potter, J. S., Marino, E. N., Hillhouse, M. P., Nielsen, S., Wiest, K. L., Canamar, C. P., Martin, J. A., Ang, A., Baker, R., Saxon, A. J., et al. (2013) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2013.74.605 · Cited by 118 · see citing works
Soyka, M., Kranzler, H. R., van den Brink, W., Krystal, J. H., Möller, H., Kasper, S. F., & The WFSBP Task Force on Treatment, G. F. S. U. D. (2011) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.561872 · Cited by 112 · see citing works
Self-citationShand, F., Degenhardt, L. J., Slade, T. N., & Nelson, E. C. (2010) · Addictive Behaviors · doi:10.1016/j.addbeh.2010.08.008 · Cited by 111 · see citing works
Klimas, J., Tobin, H. M., Field, C. J., O’Gorman, C. S., Glynn, L. G., Keenan, E., Saunders, J. A., Bury, G., Dunne, C. P., & Cullen, W. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009269.pub3 · Cited by 111 · see citing works
Change and stability of change after treatment of drug misuse
Gossop, M., Marsden, J., Stewart, D., & Treacy, S. (2002) · Addictive Behaviors · doi:10.1016/s0306-4603(00)00174-x · Cited by 109 · see citing works
Treatment of patients with substance use disorders: Second edition
Kleber, H. D., Weiss, R. D., Anton, R. F., George, T. P., Greenfield, S. F., Kosten, T. R., O’Brien, C. P., Rounsaville, B. J., Strain, E. C., Ziedonis, D. M., et al. (2006) · American Journal of Psychiatry · Cited by 107 · see citing works
Long-term Outcome of Chronic Drug Use: The Amsterdam Cohort Study among Drug Users
Termorshuizen, F. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi035 · Cited by 106 · see citing works
Treating Alcohol and Drug Abuse
(2003) · Wiley eBooks · doi:10.1002/3527601465 · Cited by 105 · see citing works
Marinelli, P. W., Quirion, R., & Gianoulakis, C. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.05.047 · Cited by 103 · see citing works
Bjørnaas, M. A., Bekken, A. S., Ojlert, A., Haldorsen, T., Jacobsen, D., Rostrup, M., & Ekeberg, Ø. (2008) · BMC Psychiatry · doi:10.1186/1471-244x-8-8 · Cited by 99 · see citing works
Marinelli, P. W., Lam, M. P., Bai, L., Quirion, R., & Gianoulakis, C. (2006) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00112.x · Cited by 98 · see citing works
Berson, A., Fau, D., Fornacciari, R., Degove-Goddard, P., Sutton, A., Descatoire, V., Haouzi, D., Lettéron, P., Moreau, A., Feldmann, G., et al. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(00)00050-7 · Cited by 98 · see citing works
Marinelli, P. W., Bai, L., Quirion, R., & Gianoulakis, C. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000183008.62955.2e · Cited by 93 · see citing works
Hepatitis after intravenous buprenorphine misuse in heroin addicts
Berson, A., Gervais, A., Cazals-Hatem, D. L., Boyer, N., Durand, F., Bernuau, J., Marcellin, P., Degott, C., Valla, D. C., & Pessayre, D. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(00)00049-0 · Cited by 92 · see citing works
Treating Alcohol and Drug Abuse – An Evidence Based Review
Berglund, P. D. M., Thelander, S., & Jonsson, P. D. E. (2003) · doi:10.1002/3527601465.contrib · Cited by 89 · see citing works
Patterns of heroin, cocaine, and alcohol abuse during long-term methadone maintenance treatment
Dobler-Mikola, A., Hättenschwiler, J. A., Meili, D., Beck, T., Böni, E., & Modestin, J. (2005) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2005.08.002 · Cited by 89 · see citing works
The effect of methadone maintenance treatment on alcohol consumption: A systematic review
Srivastava, A., Kahan, M., & Ross, S. (2007) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2007.04.001 · Cited by 83 · see citing works
New Pharmacological Treatment Strategies for Relapse Prevention
Spanagel, R., & Vengeliene, V. (2012) · Current topics in behavioral neurosciences · doi:10.1007/7854_2012_205 · Cited by 80 · see citing works
Critical issues in the treatment of hepatitis C virus infection in methadone maintenance patients
Novick, D. M., & Kreek, M. J. (2008) · Addiction · doi:10.1111/j.1360-0443.2008.02188.x · Cited by 77 · see citing works
Elevated Liver Enzyme Levels in Opioid‐Dependent Patients with Hepatitis Treated with Buprenorphine
Petry, N. M., Bickel, W. K., Piasecki, D. P., Marsch, L. A., & Badger, G. J. (2000) · American Journal on Addictions · doi:10.1080/10550490050148099 · Cited by 76 · see citing works
Patterns of drinking and drinking outcomes among drug misusers
Gossop, M., Marsden, J., Stewart, D., & Rolfe, A. (2000) · Journal of Substance Abuse Treatment · doi:10.1016/s0740-5472(99)00097-5 · Cited by 75 · see citing works
Stenbacka, M., Beck, O., Leifman, A., Romelsjö, A., & Helander, A. (2007) · Drug and Alcohol Review · doi:10.1080/09595230601036994 · Cited by 74 · see citing works
Bloodborne viral infection in Irish injecting drug users
Smyth, B. P., Keenan, E., & O'Connor, J. J. (1998) · Addiction · doi:10.1046/j.1360-0443.1998.931116493.x · Cited by 73 · see citing works
Effect of motivational interviewing on reduction of alcohol use
Nyamathi, A., SHOPTAW, S. J., Cohen, A. J., Greengold, B., Nyamathi, K., Marfisee, M., de Castro, V., Khalilifard, F., George, D., & LEAKE, B. D. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.08.021 · Cited by 73 · see citing works
Alcoholism and Methadone Treatment: Consequences for the Patient and Program
Joseph, H., & Appel, P. (1985) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952998509016848 · Cited by 72 · see citing works
Excessive alcohol consumption is associated with reduced quality of life among methadone patients
Senbanjo, R., Wolff, K., & Marshall, J. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01683.x · Cited by 71 · see citing works
Oliveto, A. H., Poling, J. C., Mancino, M. J., Feldman, Z., Cubells, J. F., Pruzinsky, R., Gonsai, K., Cargile, C. S., Sofuoglu, M., Chopra, M. P., et al. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.07.022 · Cited by 70 · see citing works
Comparison of opiate-primary treatment-seekers with and without alcohol use disorder
Hartzler, B., Donovan, D., & Huang, Z. (2010) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2010.05.008 · Cited by 70 · see citing works
Hepatitis C and Substance Use in a Sample of Homeless People in New York City
Rosenblum, A., Nuttbrock, L. A., McQuistion, H. L., Magura, S., & Joseph, H. (2001) · Journal of Addictive Diseases · doi:10.1300/j069v20n04_03 · Cited by 68 · see citing works
Anglin, M. D., Almog, I., Fisher, D. G., & Peters, K. R. (1989) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952998909092720 · Cited by 68 · see citing works
Predictive Factors for Relapse in Patients on Buprenorphine Maintenance
Ferri, M., Finlayson, A. J. R., Wang, L., & Martin, P. R. (2014) · The American Journal on Addictions · doi:10.1111/j.1521-0391.2013.12074.x · Cited by 66 · see citing works
Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake
Barson, J. R., Carr, A., Soun, J. E., Sobhani, N. C., Rada, P. V., LEIBOWITZ, S. F., & Hoebel, B. G. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.01084.x · Cited by 64 · see citing works
A randomized trial of a brief alcohol intervention for needle exchangers (BRAINE)
Stein, M. D., Charuvastra, A., Maksad, J., & Anderson, B. J. (2002) · Addiction · doi:10.1046/j.1360-0443.2002.00102.x · Cited by 63 · see citing works
Fairbank, J. A., Dunteman, G., & Condelli, W. S. (1993) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952999309001635 · Cited by 62 · see citing works
Koob, G. F., Roberts, A. J., Kieffer, B. L., Heyser, C. J., Katner, S. N., Ciccocioppo, R., & Weiss, F. (2002) · Springer eBooks · doi:10.1007/0-306-47939-7_19 · Cited by 61 · see citing works
Reid, L. D. (1996) · Alcohol · doi:10.1016/0741-8329(95)02033-0 · Cited by 61 · see citing works
Prevalence of problem alcohol use among patients attending primary care for methadone treatment
Ryder, N., Cullen, W., Barry, J., Bury, G., Keenan, E., & Smyth, B. P. (2009) · BMC Family Practice · doi:10.1186/1471-2296-10-42 · Cited by 61 · see citing works
Maremmani, I., & Gerra, G. (2010) · American Journal on Addictions · doi:10.1111/j.1521-0391.2010.00086.x · Cited by 59 · see citing works
Carroll, K. M., Nich, C., Shi, J. M., Eagan, D. A., & Ball, S. A. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.05.019 · Cited by 59 · see citing works
METABOLIC INTERACTIONS BETWEEN OPIATES AND ALCOHOL *
Kreek, M. J. (1981) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1981.tb12789.x · Cited by 56 · see citing works
New Pharmacological Treatment Strategies for Relapse Prevention
Spanagel, R., & Vengeliene, V. (2012) · Current topics in behavioral neurosciences · doi:10.1007/978-3-642-28720-6_205 · Cited by 56 · see citing works
Dai, X., Thavundayil, J., & Gianoulakis, C. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000187599.17786.4a · Cited by 52 · see citing works
Acute hepatitis due to buprenorphine administration
Herv, S., Riachi, G., Noblet, C., Guillement, N., Tanasescu, S., Goria, O., Thuillez, C., Tranvouez, J. L., Ducrotte, P. R., & Lerebours, É. (2004) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200410000-00013 · Cited by 49 · see citing works
Methadone Patients and Alcohol Abuse
Ottomanelli, G. A. (1999) · Journal of Substance Abuse Treatment · doi:10.1016/s0740-5472(98)00030-0 · Cited by 49 · see citing works
Mammen, K., & Bell, J. R. (2009) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560903213405 · Cited by 48 · see citing works
Backmund, M., Schütz, C. G., Meyer, K., Eichenlaub, D., & Soyka, M. (2003) · European Addiction Research · doi:10.1159/000067733 · Cited by 48 · see citing works
Self-citationAcute liver and renal failure during treatment with buprenorphine at therapeutic dose
Zuin, M. G., Giorgini, A., Selmi, C. F., Battezzati, P. M., Cocchi, C. A., Crosignani, A., Benetti, A., Invernizzi, P., & Podda, M. (2008) · Digestive and Liver Disease · doi:10.1016/j.dld.2007.12.014 · Cited by 45 · see citing works
Dahl, H., Carlsson, A. V., Hillgren, K., & Helander, A. (2011) · Alcohol and Alcoholism · doi:10.1093/alcalc/agr009 · Cited by 44 · see citing works
Huang, C. L.-C., & Lee, C. W. (2012) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2012.08.003 · Cited by 43 · see citing works
Wurst, F. M., Dürsteler‐MacFarland, K. M., Auwärter, V., Ergovic, S., Thon, N., Yegles, M., Halter, C. C., Weinmann, W., & Wiesbeck, G. A. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00724.x · Cited by 43 · see citing works
The treatment of alcoholic methadone patients: A review
Bickel, W. K., Marion, I. J., & Lowinson, J. H. (1987) · Journal of Substance Abuse Treatment · doi:10.1016/0740-5472(87)90005-5 · Cited by 42 · see citing works
Nalmefene for the treatment of alcohol dependence: a current update
Soyka, M. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713001284 · Cited by 42 · see citing works
Self-citationAlcohol Consumption during Methadone Maintenance Treatment
Rittmannsberger, H., Silberbauer, C., Lehner, R., & Ruschak, M. (2000) · European Addiction Research · doi:10.1159/000019003 · Cited by 39 · see citing works
SHORT-TERM METHADONE ADMINISTRATION REDUCES ALCOHOL CONSUMPTION IN NON-ALCOHOLIC HEROIN ADDICTS
Caputo, F. (2002) · Alcohol and Alcoholism · doi:10.1093/alcalc/37.2.164 · Cited by 39 · see citing works
Kamien, J. B., Branstetter, S. A., & Amass, L. (2008) · Heroin addiction and related clinical problems · Cited by 38 · see citing works
Perceived Stress and Substance Use in Methadone-Maintained Smokers
Moitra, E., Anderson, B., & Stein, M. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.08.010 · Cited by 35 · see citing works
Constant infusions of morphine and intakes of sweetened ethanol solution among rats
Hubbell, C. L., Abelson, M. L., Burkhardt, C. A., Herlands, S. E., & Reid, L. D. (1988) · Alcohol · doi:10.1016/0741-8329(88)90029-8 · Cited by 35 · see citing works
Treatment of co-occurring alcohol and other drug use disorders.
Arias, A. J., & Kranzler, H. R. (2008) · Europe PMC (PubMed Central) · Cited by 35 · see citing works
Wang, S., Tsou, H., Chung, R., Chang, Y.-S., Fang, C., Chen, C., Ho, I.-K., Kuo, H., Liu, S. C., Shih, Y.-H., et al. (2014) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000082 · Cited by 35 · see citing works
Correlates of alcohol use among methadone-maintained adults
Nyamathi, A., Cohen, A. J., Marfisee, M., SHOPTAW, S. J., Greengold, B., de Castro, V., George, D., & LEAKE, B. D. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.10.008 · Cited by 34 · see citing works
Screening for Alcohol Use Patterns Among Methadone Maintenance Patients
Teplin, D., Raz, B., Daiter, J., Varenbut, M., & Plater, C. (2007) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990601091184 · Cited by 34 · see citing works
Peyrière, H., Tatem, L., Bories, C., Pageaux, G., Blayac, J., & Larrey, D. G. (2009) · Annals of Pharmacotherapy · doi:10.1345/aph.1l628 · Cited by 33 · see citing works
Schottenfeld, R. S., Chawarski, M. C., Cubells, J. F., George, T. P., Lappalainen, J., & Kosten, T. R. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.12.007 · Cited by 31 · see citing works
Klimas, J., Field, C. J., Cullen, W., O’Gorman, C. S., Glynn, L. G., Keenan, E., Saunders, J. A., Bury, G., & Dunne, C. P. (2013) · Systematic Reviews · doi:10.1186/2046-4053-2-3 · Cited by 31 · see citing works
Klimas, J., Field, C. J., Cullen, W., O’Gorman, C. S., Glynn, L. G., Keenan, E., Saunders, J. A., Bury, G., & Dunne, C. P. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009269.pub2 · Cited by 31 · see citing works
Hartzler, B., Donovan, D., & Huang, Z. (2011) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952990.2011.602995 · Cited by 30 · see citing works
Darker, C. D., Sweeney, B., HASSAN, H. O. E., Smyth, B. P., Ivers, J., & Barry, J. M. (2011) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2011.00349.x · Cited by 30 · see citing works
Nava, F. A., Manzato, E., Leonardi, C., & Lucchini, A. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.08.019 · Cited by 29 · see citing works
Seroprevalence of Hepatitis C in a Sample of Middle Class Substance Abusers
Abraham, H. D., Degli‐Esposti, S., & Marino, L. J. (1999) · Journal of Addictive Diseases · doi:10.1300/j069v18n04_07 · Cited by 28 · see citing works
Veldhuizen, S., & Callaghan, R. C. (2014) · Annals of Epidemiology · doi:10.1016/j.annepidem.2014.06.001 · Cited by 27 · see citing works
Bruce, R. D., & Altice, F. L. (2007) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990701653875 · Cited by 27 · see citing works
Effects of Buprenorphine and Hepatitis C on Liver Enzymes in Adolescents and Young Adults
Bogenschutz, M. P., Abbott, P. J., Kushner, R. A., Tonigan, J. S., & WOODY, G. E. (2010) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e3181c4e27e · Cited by 21 · see citing works
Longitudinal patterns of alcohol use by narcotics addicts.
Hser, Y., Anglin, M. D., & Powers, K. I. (1990) · PubMed · Cited by 20 · see citing works
Feldman, N., Chatton, A., Khan, R., Khazaal, Y., & ZULLINO, D. F. (2011) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/1747-597x-6-22 · Cited by 19 · see citing works
Wurst, F. M., Haber, P., Wiesbeck, G. A., Watson, B., Wallace, C., Whitfield, J. B., Halter, C. C., Weinmann, W., & Conigrave, K. M. (2007) · Addiction Biology · doi:10.1111/j.1369-1600.2007.00076.x · Cited by 18 · see citing works
Bickel, W. K., & Amass, L. (1993) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(93)80003-w · Cited by 18 · see citing works
Haasen, C., Eiroá‐Orosa, F. J., Verthein, U., Soyka, M., Dilg, C., Schäfer, I., & Reimer, J. (2009) · Alcohol · doi:10.1016/j.alcohol.2009.02.007 · Cited by 16 · see citing works
Self-citationKlimas, J., Anderson, R., Bourke, M., Bury, G., Field, C. J., Kaner, E., Keane, R., Keenan, E., Meagher, D. J., Murphy, B., et al. (2013) · JMIR Research Protocols · doi:10.2196/resprot.2678 · Cited by 16 · see citing works
Bennett, G. A., Edwards, S. H., & Bailey, J. (2002) · Journal of Substance Use · doi:10.1080/14659890215694 · Cited by 14 · see citing works
Self-perceived problem with alcohol use among opioid substitution treatment clients
Islam, M. M., Day, C., Conigrave, K. M., & Topp, L. (2012) · Addictive Behaviors · doi:10.1016/j.addbeh.2012.12.001 · Cited by 14 · see citing works
Opioid Treatment Program: Clinical Guidelines for methadone and buprenorphine treatment - NSW Health
Branch, A. (2006) · Cited by 12 · see citing works
Soyka, M., Backmund, M., Schmidt, P., & Apelt, S. M. (2014) · American Journal on Addictions · doi:10.1111/j.1521-0391.2014.12131.x · Cited by 10 · see citing works
Self-citationAtkinson, T. S., Sanders, N., Mancino, M. J., & Oliveto, A. H. (2013) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e3182928e02 · Cited by 10 · see citing works
Lucas, G. M., Young, A., Donnell, D. J., Richardson, P., Aramrattana, A., Shao, Y., Ruan, Y., Liu, W., Fu, L., Ma, J., et al. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.06.013 · Cited by 9 · see citing works
Klimas, J., Field, C. J., Cullen, W., O’Gorman, C. S., Glynn, L. G., Keenan, E., Saunders, J. A., Bury, G., & Dunne, C. P. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.02.305 · Cited by 9 · see citing works
Schifano, F., Martinotti, G., Cunniff, A. L., Reißner, V., Scherbaum, N., & Ghodse, H. (2012) · American Journal on Addictions · doi:10.1111/j.1521-0391.2012.00226.x · Cited by 8 · see citing works
Buprenorphine for Prescription Opioid Addiction in a Patient With Depression and Alcohol Dependence
Fishman, M. J., Wu, L.-T. T., & WOODY, G. E. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10060879 · Cited by 7 · see citing works
Mortality related to drug use in Europe public health implications
Kommission, E. (2011) · doi:10.2810/49713 · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 5
- 38 Babor TF, Grant M: From clinical research to secondary prevention international collaboration in the development of the Alcohol Use Disorders Identification Test (AUDIT). Alcohol Health Res World 1989; 13: 371-374.
- 49 White J, Irvine R: Mechanisms of fatal opioid 'overdose': a review. Addiction 1996; 91: 1765-1772.
- 62 Wittchen HU, Buhringer G, Rehm JT, Soyka M, Trader A, Mark K, Trautmann S: Der Verlauf und Ausgang von Substitutionspatienten unter den aktuellen Bedingungen der deutschen Substitutionsversorgung nach 6 Jahren. Suchtmed 2011; 13: 232-246.
- 100 Wittchen HU, Buhringer G, Rehm JT, Klotsche J: Die Stabilität der 6-Jahres-Langzeitbefunde in Premos: Ein Vergleich mit den 7-Jahresdaten ein Jahr später. Suchtmed 2011; 13: 269-271.
- 123 Houdret N, Asnar V, Szostak-Talbodec N, Leteurtre E, Humbert L, Lecomte-Houcke M, Lhermitte M, Paris JC: Hepatonephritis and massive ingestion of buprenorphine (in French). Acta Clin Belg Suppl 1999; 1: 29-31.
Cited by
Sorted by citations
Witkiewitz, K., & Vowles, K. E. (2018) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.13594 · Cited by 248 · see citing works
Neuroimmune signaling in alcohol use disorder
Erickson, E. K., Grantham, E. K., Warden, A. S., & Harris, R. A. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2018.12.007 · Cited by 224 · see citing works
Craving in Opioid Use Disorder: From Neurobiology to Clinical Practice
Kakko, J., Alho, H., Baldacchino, A., Molina, R., Nava, F. A., & Shaya, G. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00592 · Cited by 140 · see citing works
Recommendations for buprenorphine and methadone therapy in opioid use disorder: a European consensus
Dematteis, M., Auriacombe, M., D’Agnone, O., Somaini, L., Szerman, N., Littlewood, R., Alam, F., Alho, H., Benyamina, A., Bobes, J., et al. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1409722 · Cited by 141 · see citing works
Self-citationKlimas, J., Tobin, H. M., Field, C. J., O’Gorman, C. S., Glynn, L. G., Keenan, E., Saunders, J. A., Bury, G., Dunne, C. P., & Cullen, W. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009269.pub3 · Cited by 111 · see citing works
Pharmacological and Behavioral Treatment of Opioid Use Disorder
Sofuoglu, M., DeVito, E. E., & Carroll, K. M. (2018) · Psychiatric Research and Clinical Practice · doi:10.1176/appi.prcp.20180006 · Cited by 96 · see citing works
Heikman, P. K., Muhonen, L. H., & Ojanperä, I. A. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1415-y · Cited by 70 · see citing works
Soyka, M., Strehle, J., Rehm, J. T., Bühringer, G., & Wïttchen, H. (2017) · European Addiction Research · doi:10.1159/000468518 · Cited by 65 · see citing works
Self-citationAlcohol use in opioid agonist treatment
Nolan, S., Klimas, J., & Wood, E. (2016) · Addiction Science & Clinical Practice · doi:10.1186/s13722-016-0065-6 · Cited by 47 · see citing works
Klimas, J., Fairgrieve, C., Tobin, H., Field, C.-A., O'Gorman, C. S., Glynn, L. G., Keenan, E., Saunders, J., Bury, G., Dunne, C., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009269.pub4 · Cited by 40 · see citing works
Opioid epidemic and liver disease
Verna, E. C., Schluger, A., & Brown, R. S. (2019) · JHEP Reports · doi:10.1016/j.jhepr.2019.06.006 · Cited by 40 · see citing works
Dong, H., Hayashi, K., Milloy, M., DeBeck, K., Singer, J., Wong, H., Wood, E., & Kerr, T. H. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108005 · Cited by 37 · see citing works
Haider, M. R., Brown, M. J., Gupta, R. D., Karim, S., Olatosi, B., & Li, X. (2020) · Substance Use & Misuse · doi:10.1080/10826084.2020.1788086 · Cited by 30 · see citing works
Canfield, M., Norton, S., Downs, J. M., & Gilchrist, G. (2021) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2021.108365 · Cited by 29 · see citing works
Outcomes of Patients in Long-Term Opioid Maintenance Treatment
Zippel‐Schultz, B., Specka, M., Cimander, K. F., Thomas Eschenhagen, A., Gölz, J., Maryschok, M., Nowak, M., Poehlke, T., Stöver, H., Helms, T. M., et al. (2016) · Substance Use & Misuse · doi:10.1080/10826084.2016.1188946 · Cited by 28 · see citing works
Prevalence and characteristics of opioid-related deaths involving alcohol in Ontario, Canada
Gomes, T., Juurlink, D. N., Mamdani, M., Paterson, J. M., & van den Brink, W. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.07.008 · Cited by 26 · see citing works
Nordeck, C. D., Welsh, C., Schwartz, R. P., Mitchell, S. G., O’Grady, K. E., & Gryczynski, J. (2022) · Drug and Alcohol Dependence Reports · doi:10.1016/j.dadr.2022.100031 · Cited by 25 · see citing works
Alcohol use disorder and motives for prescription opioid misuse: A latent class analysis
Votaw, V. R., McHugh, R. K., & Witkiewitz, K. A. (2019) · Substance Use & Misuse · doi:10.1080/10826084.2019.1594904 · Cited by 24 · see citing works
Barré, T., Marcellin, F., Beo, V. D., Delorme, J., Rojas, T. R., Mathurin, P., Protopopescu, C., Bailly, F., Coste, M., Authier, N., et al. (2019) · Addiction · doi:10.1111/add.14820 · Cited by 24 · see citing works
Association of Opioid Use Disorder Treatment With Alcohol-Related Acute Events
Xu, K. Y., Presnall, N. J., Mintz, C. M., Borodovsky, J. T., Bhat, N. R., Bierut, L. J., & Grucza, R. A. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.0061 · Cited by 24 · see citing works
Nadai, A. S. D., Little, T. B., McCabe, S. E., & Schepis, T. S. (2019) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000429 · Cited by 23 · see citing works
Zhong, B., Xu, Y., Xie, W., Lü, J., Yu, W., & Yan, J. (2019) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000500 · Cited by 22 · see citing works
Mintz, C. M., Presnall, N. J., Xu, K. Y., Hartz, S. M., Sahrmann, J. M., Bierut, L. J., & Grucza, R. A. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108886 · Cited by 21 · see citing works
Nagpal, C., Wei, D., Vinzamuri, B., Shekhar, M., Berger, S. E., Das, S., & Varshney, K. R. (2020) · ACM Conference on Health, Inference, and Learning (CHIL) · doi:10.1145/3368555.3384456 · Cited by 20 · see citing works
The entry process of Babesia merozoites into red cells.
Ward, P. A., & Jack, R. M. (1981) · PubMed Central · Cited by 19 · see citing works
Klimas, J., Nosova, E., Socias, M. E., Nolan, S., Brar, R., Hayashi, K., Milloy, M., Kerr, T. H., & Wood, E. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.01.027 · Cited by 18 · see citing works
Fifty Years of Research on Prenatal Substances: Lessons Learned for the Opioid Epidemic
Singer, L. T., Chambers, C., Coles, C. D., & Kable, J. A. (2020) · Adversity and Resilience Science · doi:10.1007/s42844-020-00021-7 · Cited by 17 · see citing works
Mechanisms and Clinical Features of Co-Occurring Opioid and Nicotine Use
Lichenstein, S. D., Zakiniaeiz, Y., Yip, S. W., & Garrison, K. A. (2019) · Current Addiction Reports · doi:10.1007/s40429-019-00245-3 · Cited by 16 · see citing works
Witkiewitz, K. A., Votaw, V. R., Vowles, K. E., & Kranzler, H. R. (2018) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13772 · Cited by 16 · see citing works
Schuman‐Olivier, Z., Fatkin, T., Creedon, T. B., Samawi, F., Moore, S. K., Okst, K., Fredericksen, A. (., Oxnard, A. (., Roll, D., Smith, L., et al. (2023) · The American Journal on Addictions · doi:10.1111/ajad.13364 · Cited by 15 · see citing works
An Inverse Relationship Between Alcohol and Heroin Use in Heroin Users Post Detoxification
Morgan, N., Daniels, W. M. U., & Subramaney, U. (2020) · Substance Abuse and Rehabilitation · doi:10.2147/sar.s228224 · Cited by 12 · see citing works
Klimas, J., Wood, E., Nguyen, P., Dong, H., Milloy, M., Kerr, T. H., & Hayashi, K. (2016) · European Addiction Research · doi:10.1159/000444513 · Cited by 12 · see citing works
Gilmore, A. K., Jones, J. L., Moreland, A. D., Hahn, C. K., Brady, K. T., & Back, S. E. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.05.016 · Cited by 11 · see citing works
Ho, J., DeBeck, K., Milloy, M., Dong, H., Wood, E., Kerr, T. H., & Hayashi, K. (2017) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2017.1376678 · Cited by 12 · see citing works
Jones, N. R., Hickman, M., Larney, S., Nielsen, S., Ali, R. L., Murphy, T. J., Dobbins, T., Fiellin, D. A., & Degenhardt, L. J. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108354 · Cited by 11 · see citing works
Bormann, N. L., Weber, A. N., Arndt, S. V., & Lynch, A. (2023) · American Journal on Addictions · doi:10.1111/ajad.13431 · Cited by 11 · see citing works
Disulfiram attenuates morphine or methadone withdrawal syndrome in mice
de Cordé, A., Krząścik, P., Wolińska, R., Kleczkowska, P., Filip, M., & Bujalska‐Zadrożny, M. (2018) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000376 · Cited by 11 · see citing works
Castillo, F., Jones, J. D., Luba, R. R., Mogali, S., Foltin, R. W., Evans, S. M., & Comer, S. D. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173482 · Cited by 10 · see citing works
Grall‐Bronnec, M., Laforgue, E., Challet‐Bouju, G., Cholet, J., Hardouin, J.-B., Leboucher, J., Guillou-Landréat, M., & Victorri‐Vigneau, C. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00726 · Cited by 10 · see citing works
Opioid use and risks in candidates and recipients of liver transplant
Rubin, J. B., Aby, E. S., Barman, P. M., & Tincopa, M. A. (2024) · Liver Transplantation · doi:10.1097/lvt.0000000000000388 · Cited by 9 · see citing works
Amico, K. N., Arnold, M. E., Dourron, M. S., Solomon, M. G., & Schank, J. R. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06210-9 · Cited by 9 · see citing works
Eide, D., Skurtveit, S. O., Clausen, T., Hesse, M., Mravčík, V., Nechanská, B., Rolová, G., Thylstrup, B., Tjagvad, C., Seid, A. K., et al. (2023) · European Addiction Research · doi:10.1159/000530822 · Cited by 8 · see citing works
Pélissier, F., Bugat, M.-È. R., Nubukpo, P., & Franchitto, N. (2015) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000448 · Cited by 7 · see citing works
Franchitto, N., Jullian, B., Salles, J., Pélissier, F., & Rolland, B. (2017) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2017.1312340 · Cited by 7 · see citing works
Monitoring people at risk of drinking by a rapid urinary ethyl glucuronide test
Fucci, N., Gili, A., Aroni, K., Carletti, P., Pascali, V. L., & Gambelunghe, C. (2017) · Interdisciplinary Toxicology · doi:10.1515/intox-2017-0022 · Cited by 7 · see citing works
Edsall, A. E., Hoffman, K. A., Thủy, Đ. T., Phương, P., Trang, N. T., Khuyen, T. T., Trang, N. T., Kunkel, L. E., Giang, L. M., & Korthuis, P. T. (2021) · BMC Public Health · doi:10.1186/s12889-021-11783-9 · Cited by 8 · see citing works
MacDonald, M., Fonseca, P. A. D. S., Johnson, K. R., Murray, E. M., Kember, R. L., Kranzler, H. R., Mayfield, R. D., & Silva, D. A. D. S. E. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03143-z · Cited by 6 · see citing works
Substance use disorders among primary care patients screening positive for unhealthy alcohol use
Metz, V. E., Palzes, V. A., Kline‐Simon, A. H., Chi, F. W., Campbell, C. I., Weisner, C. M., & Sterling, S. (2021) · Family Practice · doi:10.1093/fampra/cmab171 · Cited by 6 · see citing works
Rolová, G., Eide, D., Gabrhelík, R., Odsbu, I., Clausen, T., & Skurtveit, S. O. (2023) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/s13011-023-00557-8 · Cited by 6 · see citing works
Roache, J. D., Pavlicová, M., Campbell, A. N. C., Choo, T.-H. J., Peavy, M., Kermack, A. S., Nunes, E. V., & Rotrosen, J. (2021) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14729 · Cited by 6 · see citing works
Quraishi, R., Varshney, M., Singh, A. K., Singh, D., Kumar, M., Rao, R., Jain, R., & Ambekar, A. (2019) · Indian Journal of Psychological Medicine · doi:10.4103/ijpsym.ijpsym_304_19 · Cited by 6 · see citing works
Vannier, A., Fomin, V., Chung, R. T., Patel, S. J., Schaefer, E. A. K., Goodman, R. P., & Luther, J. (2022) · Gastro Hep Advances · doi:10.1016/j.gastha.2022.02.004 · Cited by 5 · see citing works
Klimas, J., Mok, W. Y., Lake, S., Socias, M. E., DeBeck, K., Hayashi, K., Wood, E., & Milloy, M. (2021) · Journal of Substance Use · doi:10.1080/14659891.2021.1941341 · Cited by 5 · see citing works
Prevalence of Heavy Alcohol Use Among People Receiving Methadone Following Change to Methadose
Klimas, J., Wood, E., Nosova, E., Milloy, M., Kerr, T. H., & Hayashi, K. (2017) · Substance Use & Misuse · doi:10.1080/10826084.2017.1302960 · Cited by 5 · see citing works
Gong, Y., Zhang, L., Long, J., Wu, Q., Zhang, J., Bao, J., Du, J., & Du, Z. (2022) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000001101 · Cited by 4 · see citing works
Radcliffe, P., Canfield, M., d’Oliveira, A. F. P. L., Finch, E., Segura, L., Torrens, M., & Gilchrist, G. (2019) · Drugs Education Prevention and Policy · doi:10.1080/09687637.2019.1658715 · Cited by 4 · see citing works
Unhealthy Alcohol use in Primary Care Patients who Screen Positive for Drug Use
Maynié-François, C., Cheng, D. M., Samet, J. H., Lloyd-Travaglini, C. A., Palfai, T. P., Bernstein, J., & Saitz, R. (2016) · Substance Abuse · doi:10.1080/08897077.2016.1216920 · Cited by 4 · see citing works
Rafiemanesh, H., Rahimi‐Movaghar, A., Shadloo, B., Abadi, Y. R., Nedjat, S., & Yazdani, K. (2022) · Journal of Substance Use · doi:10.1080/14659891.2021.2020346 · Cited by 3 · see citing works
Barker, B., Min, J. E., Homayra, F., Piske, M., Sabeti, S., Meilleur, L. R., Nosyk, B., & Wieman, N. (2023) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2023.110908 · Cited by 3 · see citing works
Opioid Dependence Risk Factors and Risk Assessment
McAnally, H. B. (2017) · Springer eBooks · doi:10.1007/978-3-319-47497-7_10 · Cited by 3 · see citing works
Post-Combat-Injury Opioid Prescription and Alcohol Use Disorder in the Military
Alcover, K. C., Poltavskiy, E. A., Howard, J. T., Watrous, J. R., Janak, J. C., Walker, L. E., & Stewart, I. J. (2022) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2022.07.010 · Cited by 2 · see citing works
Ramdin, C., Santos, C. D., & Nelson, L. S. (2022) · Alcohol and Alcoholism · doi:10.1093/alcalc/agac061 · Cited by 1 · see citing works
León, G., Bae, J., Coles, C., Batts, C., Schmidt, A., Akana, N., Smith, C. L., McPherson, S., & Miguel, A. (2025) · American Journal on Addictions · doi:10.1111/ajad.70075 · Cited by 1 · see citing works
Association illogique nalméfène et opioïdes : analyse dans la base française de pharmacovigilance
Favrelière, S., Lafay‐Chebassier, C., Fauconneau, B., Quillet, A., Yelehe‐Okouma, M., Montastruc, F., & Pérault‐Pochat, M. (2018) · Therapies · doi:10.1016/j.therap.2018.06.004 · Cited by 1 · see citing works
Opioid Abuse and Opioid Epidemic
Dasgupta, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820075-9.00003-x · Cited by 1 · see citing works
Quraishi, R., Varshney, M., Rao, R., & Ambekar, A. (2022) · Indian Journal of Psychiatry · doi:10.4103/indianjpsychiatry.indianjpsychiatry_88_22 · Cited by 1 · see citing works
Noroozi, A., & Danesh, A. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1134683 · Cited by 1 · see citing works
Klymchuk, V., Горбунова, В., & Ivanchuk, I. (2024) · Academia Mental Health and Well-Being · doi:10.20935/mhealthwellb6210 · Cited by 1 · see citing works
Ganesh, N., Kaur, M., Rashid, R. B. A., Parameswaran, R., Hashim, A. H., Hoong, M. C., Amit, N., Siau, C. S., & Ng, C. G. (2024) · Psychiatry International · doi:10.3390/psychiatryint5030025 · Cited by 1 · see citing works
Use of psychoactive substances in the regional methadone center in Serbia
Popović, T., Dickov, A., Knežević, V., Ivanović-Kovačević, S., & Nikolić, B. S. (2024) · Zdravstvena zastita · doi:10.5937/zdravzast53-51866 · Cited by 1 · see citing works
Roser, P., Specka, M., Bonnet, U., Kuhlmann, T., Kühnhold, S., Steinert, R., Zeiske, B., Deimel, D., & Scherbaum, N. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1467144 · Cited by 1 · see citing works
Alshehri, F. S. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1503035
Oliveto, A. H., McGaugh, J., Chopra, M. P., Thostenson, J., & Mancino, M. J. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.04.051
Janssen, É., Vuolo, M., Véron, S., & Laffont, I. F. (2025) · Drug and Alcohol Review · doi:10.1111/dar.14078
Rolová, G., Eide, D., Gabrhelík, R., Odsbu, I., Clausen, T., & Skurtveit, S. O. (2023) · Figshare · doi:10.6084/m9.figshare.23803159
Using PEth and AUDIT-4 to Detect Harmful Alcohol Use Among People with Severe Substance Use
Auestad, N., Jørgenrud, B., Bogstrand, S. T., Vallersnes, O. M., Lerdal, A., & Wüsthoff, L. E. C. (2026) · Substance Use & Misuse · doi:10.1080/10826084.2026.2634253
Qeadan, F., & Barbeau, W. A. (2026) · Drug and Alcohol Dependence Reports · doi:10.1016/j.dadr.2026.100474
- Authors
- Soyka, M.
- Affiliations
- Privatklinik Meiringen (CH)
- Corresponding author
- Soyka, Michael
- ORCID
- Soyka, Michael
- Venue
- European Addiction Research
- Publisher
- S. Karger AG
- Published
- 2014-11-19
- Volume
- 21
- Issue
- 2
- Pages
- 78-87
- ISSN
- 1022-6877 (ISSN-L)
- 1421-9891
- OpenAlex
- W2048849975
- Cited by
- 77
- References
- 129
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 6 · 2023: 6 · 2022: 10 · 2021: 7 · 2020: 7 · 2019: 10 · 2018: 9 · 2017: 9 · 2016: 4 · 2015: 1 · 2014: 1
- FWCI
- 0.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Addiction Research (publishedVersion)
- PubMed (publishedVersion)
- Open access LMU (Ludwid Maxmilian's Universitat Munchen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- alcoholism, opioid maintenance treatment, opioid use disorder, methadone, buprenorphine, alcohol consumption, comorbidities, hepatotoxicity, treatment non-adherence, brief intervention, prevalence, mortality risk
- MeSH terms
- Alcohol Drinking, Brain, Buprenorphine, Humans, Methadone, Opioid-Related Disorders, Narcotics, Comorbidity, Prevalence, Alcohol-Related Disorders, Chemical and Drug Induced Liver Injury, Opiate Substitution Treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
