FOXO3: A Major Gene for Human Longevity - A Mini-Review

A C. elegans mutant that lives twice as long as wild type

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The genetics of ageing

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Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

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A Mutant Drosophila Insulin Receptor Homolog That Extends Life-Span and Impairs Neuroendocrine Function

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FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

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Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

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Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

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Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue

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Akt, FoxO and regulation of apoptosis

Zhang, X., Tang, N., Hadden, T. J., & Rishi, A. K. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2011.03.010 · Cited by 1,149

FOXOs: signalling integrators for homeostasis maintenance

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Chlorogenic Acid Activates Nrf2/SKN-1 and Prolongs the Lifespan of Caenorhabditis elegans via the Akt-FOXO3/DAF16a-DDB1 Pathway and Activation of DAF16f

Siswanto, F. M., Sakuma, R., Oguro, A., & Imaoka, S. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac062 · Cited by 34

Longevity-AssociatedFOXO3Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations

Willcox, B. J., Morris, B. J., Tranah, G. J., Chen, R., Masaki, K., He, Q., Willcox, D. C., Allsopp, R., Moisyadi, S., Gerschenson, M., et al. (2016) · The Journals of Gerontology Series A · doi:10.1093/gerona/glw196 · Cited by 34

Ginsenoside Rg1 protects against Sca‑1+ HSC/HPC cell aging by regulating the SIRT1‑FOXO3 and SIRT3‑SOD2 signaling pathways in a γ‑ray irradiation‑induced aging mice model

Tang, Y., Zhou, Y., Wang, Y., He, Y., Ding, J.-C., Li, Y., & Wang, C. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8810 · Cited by 34

Extracellular vesicles secreted by adenomyosis endometrial organoids contain miRNAs involved in embryo implantation and pregnancy

Juárez‐Barber, E., Segura-Benítez, M., Carbajo‐García, M. C., Bas-Rivas, A., Faus, A., Vidal, C., Gilés, J., Labarta, E., Pellicer, A., Cervelló, I., et al. (2022) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.12.008 · Cited by 34

Genetic enhancement: an avenue to combat aging-related diseases

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The Hydra stem cell system – Revisited

Holstein, T. W. (2023) · Cells and Development · doi:10.1016/j.cdev.2023.203846 · Cited by 32

Untangling Aging Using Dynamic, Organism-Level Phenotypic Networks

Freund, A. (2019) · Cell Systems · doi:10.1016/j.cels.2019.02.005 · Cited by 32

Proteasome inhibitor MG132 induces apoptosis in human osteosarcoma U2OS cells

Lee, H. K., Park, S., & Nam, M. J. (2021) · Human & Experimental Toxicology · doi:10.1177/09603271211017972 · Cited by 32

Keeping up with the Red Queen: the pace of aging as an adaptation

Lenárt, P., & Vašků, J. B. (2016) · Biogerontology · doi:10.1007/s10522-016-9674-4 · Cited by 31

miR‑122 promotes proliferation and invasion of clear cell renal cell carcinoma by suppressing Forkhead box O3

Nie, W., Ni, D., Ma, X., Zhang, Y., Gao, Y., Peng, C., & Zhang, X. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4636 · Cited by 32

p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6

Cheng, Y., Zhang, M., Xu, R. H., Fu, L., Xue, M., Xu, C., Tang, C., Fang, T., Liu, X., Sun, B., et al. (2024) · Experimental Gerontology · doi:10.1016/j.exger.2024.112391 · Cited by 30

Genetics of frailty: A longevity perspective

Sathyan, S., & Verghese, J. (2020) · Translational research · doi:10.1016/j.trsl.2020.03.005 · Cited by 32

Stem Cell Transcription Factor FoxO Controls Microbiome Resilience in Hydra

Mortzfeld, B. M., Taubenheim, J., Fraune, S., Klimovich, A. V., & Bosch, T. C. G. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00629 · Cited by 33

MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation

Che, J., Xu, C., Wu, Y., Jia, P., Han, Q., Ma, Y.-T., Wang, X., & Zheng, Y. (2021) · Skeletal Muscle · doi:10.1186/s13395-021-00262-9 · Cited by 29

The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis

Löbel, M., Holzhauser, L., Hartwig, J., Shukla, P. C., Savvatis, K., Jenke, A., Gast, M., Escher, F., Becker, S. C., Bauer, S., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx624 · Cited by 29

FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease

Chen, R., Morris, B. J., Donlon, T. A., Masaki, K., Willcox, D. C., Davy, P. M. C., Allsopp, R., & Willcox, B. J. (2020) · Aging · doi:10.18632/aging.202175 · Cited by 28

[Corrigendum] miR‑122 promotes proliferation and invasion of clear cell renal cell carcinoma by suppressing Forkhead box O3

Nie, W., Ni, D., Ma, X., Zhang, Y., Gao, Y., Peng, C., & Zhang, X. (2019) · International Journal of Oncology · doi:10.3892/ijo.2019.4694 · Cited by 28

Gene- and Gender-Related Decrease in Serum BDNF Levels in Alzheimer’s Disease

Piancatelli, D., Aureli, A., Sebastiani, P., Colanardi, A., Beato, T. D., Cane, L. D., Sucapane, P., Marini, C., & Loreto, S. D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314599 · Cited by 29

DNA damage and oxidative stress in long-lived aquatic organisms

Wojtczyk-Miaskowska, A., & Schlichtholz, B. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.07.003 · Cited by 28

Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3′UTR intron-containing NMD targets

Gangras, P., Gallagher, T. L., Patton, R. D., Yi, Z., Parthun, M. A., Tietz, K. T., Deans, N. C., Bundschuh, R. A., Amacher, S. L., & Singh, G. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008830 · Cited by 29

Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis

Xu, X., Xu, X., Wang, X., & Shen, L. (2023) · Pharmaceutical Biology · doi:10.1080/13880209.2023.2208636 · Cited by 25

Association Analysis ofFOXO3Longevity Variants With Blood Pressure and Essential Hypertension

Morris, B. J., Chen, R., Donlon, T. A., Evans, D. S., Tranah, G. J., Parimi, N., Ehret, G., Newton‐Cheh, C., Seto, T. B., Willcox, D. C., et al. (2015) · American Journal of Hypertension · doi:10.1093/ajh/hpv171 · Cited by 25

Blunting Autoantigen-induced FOXO3a Protein Phosphorylation and Degradation Is a Novel Pathway of Glucocorticoids for the Treatment of Systemic Lupus Erythematosus

Lu, M., Xu, W., Gao, B., & Xiong, S. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.728840 · Cited by 25

Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape

Grossi, V., Fasano, C., Celestini, V., Signorile, M. L., Sanese, P., & Simone, C. (2019) · Cancers · doi:10.3390/cancers11030414 · Cited by 25

A molecular perspective on age-dependent changes to the heat shock axis

Trivedi, R., & Jurivich, D. A. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.110969 · Cited by 25

Advances in SIRT3 involvement in regulating autophagy-related mechanisms

Xi, S., Chen, W., & Ke, Y. (2024) · Cell Division · doi:10.1186/s13008-024-00124-y · Cited by 27

MiR-940 promotes malignant progression of breast cancer by regulating FOXO3

Zhang, H., Peng, J., Lai, J., Liu, H., Zhang, Z., Li, X., Liang, B., Chen, X., Zou, B., Lin, S., et al. (2020) · Bioscience Reports · doi:10.1042/bsr20201337 · Cited by 25

Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF‐16‐induced longevity

McIntyre, R. L., Denis, S. W., Kamble, R., Molenaars, M., Petr, M. A., Schomakers, B. V., Rahman, M., Gupta, S. D., Tóth, M. L., Vanapalli, S. A., et al. (2021) · Aging Cell · doi:10.1111/acel.13381 · Cited by 23

Gastrodia elata and parishin ameliorate aging induced ‘leaky gut’ in mice: Correlation with gut microbiota

Gong, C., Ma, C., Irge, D. D., Li, S., Chen, S.-M., Zhou, S., Zhao, X., Li, H., Li, J., Yang, Y., et al. (2022) · Biomedical Journal · doi:10.1016/j.bj.2022.07.001 · Cited by 26

Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans

Wang, Y. A., Kammenga, J. E., & Harvey, S. C. (2017) · Human Genomics · doi:10.1186/s40246-017-0108-4 · Cited by 22

Delayed Feeding Alters Transcriptional and Post-Transcriptional Regulation of Hepatic Metabolic Pathways in Peri-Hatch Broiler Chicks

Hicks, J. A., Porter, T. E., Sunny, N. E., & Liu, H. (2019) · Genes · doi:10.3390/genes10040272 · Cited by 23

The potential drug for treatment in pancreatic adenocarcinoma: a bioinformatical study based on distinct drug databases

Liu, H., Zhou, Q., Wei, W., Qi, B., Zeng, F., Bao, N., Li, Q., Guo, F., & Xia, S. (2020) · Chinese Medicine · doi:10.1186/s13020-020-00309-x · Cited by 25

Acetylshikonin Induces Apoptosis in Human Colorectal Cancer HCT‐15 and LoVo Cells via Nuclear Translocation of FOXO3 and ROS Level Elevation

Lim, H. M., Lee, J., Nam, M. J., & Park, S. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/6647107 · Cited by 24

Proteomics and Epidemiological Models of Human Aging

Ubaida‐Mohien, C., Moaddel, R., Moore, A. Z., Kuo, P., Faghri, F., Tharakan, R., Tanaka, T., Nalls, M. A., & Ferrucci, L. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.674013 · Cited by 23

Research progress on aging mechanism and drugs and the role of stem cells in anti-aging process

Zhang, Y., Li, Q., Niu, Y., Wei, K., Wang, X., Niu, B., & Zhang, L. (2023) · Experimental Gerontology · doi:10.1016/j.exger.2023.112248 · Cited by 24

Emerging links between FOXOs and diabetic complications

Parmar, U. M., Jalgaonkar, M. P., Kansara, A. J., & Oza, M. J. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176089 · Cited by 23

Metformin induces the AP-1 transcription factor network in normal dermal fibroblasts

Gillespie, Z. E., Wang, C., Vadan, F., Yu, T. Y., Ausió, J., KUSALIK, A. J., & Eskiw, C. H. (2019) · Scientific Reports · doi:10.1038/s41598-019-41839-1 · Cited by 28

Oxidized multiwalled carbon nanotube reinforced rheological examination on Gum ghatti‐ cl‐poly (acrylic acid) hydrogels

Kamaliya, B. P., Dave, P. N., & Macwan, P. M. (2022) · Journal of Applied Polymer Science · doi:10.1002/app.52888 · Cited by 22

Anti-Aging Potential of Bioactive Phytoconstituents Found in Edible Medicinal Plants: A Review

Iweala, E., Adurosakin, O. E., Ugochukwu, I., Omonhinmin, C. A., Dania, O. E., & Ugbogu, E. A. (2024) · Sci · doi:10.3390/sci6020036 · Cited by 21

Chaperones vs. oxidative stress in the pathobiology of ischemic stroke

Soldatov, V. O., Venediktov, A. A., Белых, А. Е., Piavchenko, G. A., Naimzada, M. D., Ogneva, N., Kartashkina, N. L., & Bushueva, O. Y. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1513084 · Cited by 22

FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1

Ferreira, F. J., Galhardo, M., Nogueira, J. M., Teixeira, J., Logarinho, E., & Bessa, J. (2025) · Nature Communications · doi:10.1038/s41467-025-57503-4 · Cited by 27

Diabetic complications within the context of aging: Nicotinamide adenine dinucleotide redox, insulin C‐peptide, sirtuin 1–liver kinase B1–adenosine monophosphate‐activated protein kinase positive feedback and forkhead box O3

Ido, Y. (2016) · Journal of Diabetes Investigation · doi:10.1111/jdi.12485 · Cited by 20

Variable DNA methylation of aging-related genes is associated with male COPD

Du, X., Yuan, L., Wu, M., Men, M.-C., He, R., Wang, L., Wu, S., Xiang, Y., Qu, X., Liu, H., et al. (2019) · Respiratory Research · doi:10.1186/s12931-019-1215-7 · Cited by 17

BUB1 predicts poor prognosis and immune status in liver hepatocellular carcinoma

Qi, W., Bai, Y., Wang, Y., Liu, L., Yaqing, Z., Yu, Y., & Chen, H. (2022) · Apmis · doi:10.1111/apm.13219 · Cited by 21

Effect of FOXO3 and Air Pollution on Cognitive Function: A Longitudinal Cohort Study of Older Adults in China From 2000 to 2014

Ji, J. S., Liu, L., Zeng, Y., & Yan, L. L. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac016 · Cited by 25

Molecular and Structural Alterations of Skeletal Muscle Tissue Nuclei during Aging

Cisterna, B., & Malatesta, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031833 · Cited by 27

Adverse Childhood Experiences among a Community of Resilient Centenarians and Seniors: Implications for a Chronic Disease Prevention Framework

Spencer-Hwang, R., Beltrán, X. T., Valladares, J., Pasco-Rubio, M., Dougherty, M., & Kim, W. (2018) · The Permanente Journal · doi:10.7812/tpp/17-146 · Cited by 21

Mechanisms of stress-related muscle atrophy in fish: An ex vivo approach

Torres-Velarde, J. M., Llera‐Herrera, R., García-Gasca, T., & Garcı́a-Gasca, A. (2018) · Mechanisms of Development · doi:10.1016/j.mod.2018.07.002 · Cited by 19

Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3

Jiménez, L., da Silva, A. M., Calissi, G., Grenho, I., Monteiro, A. R., Mayoral-Varo, V., Blanco‐Aparicio, C., Pastor, J., Bustos, V., Bracher, F., et al. (2021) · The Journals of Gerontology Series A · doi:10.1093/gerona/glab265 · Cited by 19

Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-Year Prospective Longitudinal Cohort Study

Ji, J. S., Liu, L., Shu, C., Yan, L. L., & Zeng, Y. (2022) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glab378 · Cited by 19

Metformin Inhibits HaCaT Cell Proliferation Under Hyperlipidemia Through Reducing Reactive Oxygen Species via FOXO3 Activation

Zhang, L., Liu, X., Huang, M., Wang, R., Zhu, W., Li, Y., Shen, L., & Li, C. (2022) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s368845 · Cited by 19

Anti-photoaging potential of propolis extract in UVB-irradiated human dermal fibroblasts through increasing the expression of FOXO3A and NGF genes

Ebadi, P., & Fazeli, M. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.08.019 · Cited by 19

Amyloid precursor protein intracellular domain-dependent regulation of FOXO3a inhibits adult hippocampal neurogenesis

Jiang, M. H., Vanan, S., Tu, H., Zhang, W., Zhang, Z.-W., Chia, S., Jang, S. E., Zeng, X., Yu, W., Xu, J., et al. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.07.031 · Cited by 19

Plasma proteomics identify novel biomarkers and dynamic patterns of biological aging

Ma, L., Liu, W., He, Y., Zhang, Y., You, J., Feng, J., Tan, L., Cheng, W., & Yu, J.-T. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.05.004 · Cited by 23

Mitochondria in biology and medicine – 2023

Disha, B., Mathew, R. P., Dalal, A. B., Mahato, A. K., Satyamoorthy, K., Singh, K. K., Kumarasamy Thangaraj, K., & Govindaraj, P. (2024) · Mitochondrion · doi:10.1016/j.mito.2024.101853 · Cited by 20

Stress-induced modulation of volume-regulated anions channels in human alveolar carcinoma cells

Bach, M. D., Sørensen, B. H., & Lambert, I. H. (2018) · Physiological Reports · doi:10.14814/phy2.13869 · Cited by 18

Mechanistic insights into the role of FOXO in diabetic retinopathy.

Behl, T., Wadhwa, M., Sehgal, A., Singh, S., Sharma, N., Bhatia, S., Al‐Harrasi, A., Aleya, L., & BUNGAU, S. G. (2022) · PubMed Central · Cited by 15

Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in Okinawans

Torigoe, T. H., Willcox, D. C., Shimabukuro, M., Higa, M., Gerschenson, M., Andrukhiv, A., Suzuki, M., Morris, B. J., Chen, R., Gojanovich, G. S., et al. (2024) · npj Aging · doi:10.1038/s41514-024-00142-8 · Cited by 18

Exosomal YB-1 facilitates ovarian restoration by MALAT1/miR-211-5p/FOXO3 axis

Zhang, M., Xing, J., Zhao, S., Lu, M., Liu, Y., Li, L., Gao, W., Chen, L., Li, W., Shang, J., et al. (2024) · Cell Biology and Toxicology · doi:10.1007/s10565-024-09871-8 · Cited by 17

Eco-Aging: stem cells and microbes are controlled by aging antagonist FoxO

Mortzfeld, B. M., & Bosch, T. C. G. (2017) · Current Opinion in Microbiology · doi:10.1016/j.mib.2017.06.009 · Cited by 17

Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure

Kim, J. H., Kang, D.-J., Bae, J.-S., Lee, J. H., Jeon, S., Choi, H., Kim, N., Kim, H., & Kim, H. R. (2021) · Scientific Reports · doi:10.1038/s41598-021-87263-2 · Cited by 23

The Roles and Pathogenesis Mechanisms of a Number of Micronutrients in the Prevention and/or Treatment of Chronic Hepatitis, COVID-19 and Type-2 Diabetes Mellitus

Sumaily, K. M. (2022) · Nutrients · doi:10.3390/nu14132632 · Cited by 17

Emerging Biomedical Applications of the Vesicular Stomatitis Virus Glycoprotein

Rehman, S., Bishnoi, S., Roy, R., Kumari, A., Jayakumar, H., Gupta, S., Kar, P., Pattnaik, A. K., & Nayak, D. (2022) · ACS Omega · doi:10.1021/acsomega.2c03517 · Cited by 16

Single‐Cell Transcriptomics Reveals Longevity Immune Remodeling Features Shared by Centenarians and Their Offspring

Dong, C., Miao, Y., Zhao, R. Z., Yang, M., Guo, A., Xue, Z., Li, T., Zhang, Q., Bao, Y., Shen, C., et al. (2022) · Advanced Science · doi:10.1002/advs.202204849 · Cited by 16

miR−122−5p Regulates Renal Fibrosis In Vivo

Kaneko, S., Yanai, K., Ishii, H., Aomatsu, A., Hirai, K., Ookawara, S., Ishibashi, K., & Morishita, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315423 · Cited by 16

Fortification of Iron Oxide as Sustainable Nanoparticles: An Amalgamation with Magnetic/Photo Responsive Cancer Therapies

Rethi, L., Rethi, L., Liu, C., Hyun, T. V., Chen, C., & Chuang, E. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s404394 · Cited by 17

The Roles of White Adipose Tissue and Liver NADPH in Dietary Restriction-Induced Longevity

Jamerson, L. E., & Bradshaw, P. C. (2024) · Antioxidants · doi:10.3390/antiox13070820 · Cited by 22

Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele

Davy, P. M. C., Willcox, D. C., Shimabukuro, M., Donlon, T. A., Torigoe, T. H., Suzuki, M., Higa, M., Masuzaki, H., Sata, M., Chen, R., et al. (2018) · The Journals of Gerontology Series A · doi:10.1093/gerona/gly071 · Cited by 16

Alleviation of CCCP-induced mitochondrial injury by augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy

Zhang, J., Chen, S., Li, Y., Xiao, W., & An, W. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112866 · Cited by 15

Hydra’s Lasting Partnership with Microbes: The Key for Escaping Senescence?

He, J., & Bosch, T. C. G. (2022) · Microorganisms · doi:10.3390/microorganisms10040774 · Cited by 15

Progress Toward a Multiomic Understanding of Traumatic Brain Injury: A Review

Kocheril, P. A., Moore, S. C., Lenz, K. D., Mukundan, H., & Lilley, L. M. (2022) · Biomarker Insights · doi:10.1177/11772719221105145 · Cited by 16

Sixteen kiwi (Apteryx spp) transcriptomes provide a wealth of genetic markers and insight into sex chromosome evolution in birds

Ramstad, K. M., Miller, H. C., & Kolle, G. (2016) · BMC Genomics · doi:10.1186/s12864-016-2714-2 · Cited by 15

Novel Functional, Health, and Genetic Determinants of Cognitive Terminal Decline: Kuakini Honolulu Heart Program/Honolulu-Asia Aging Study

Margrett, J. A., Schofield, T. J., Martin, P., Poon, L. W., Masaki, K., Donlon, T. A., Kallianpur, K. J., & Willcox, B. J. (2021) · The Journals of Gerontology Series A · doi:10.1093/gerona/glab327 · Cited by 16

FOXO3, a Molecular Search for the Fountain of Youth

Fibbe, W. E., & Shi, Y. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.02.008 · Cited by 15

Muscle Aging Heterogeneity: Genetic and Structural Basis of Sarcopenia Resistance

Андреевна, Т. А., Bilyalov, A. I., Filatov, N. S., Perepechenov, S., Kupriyanova, D. S., Brovkin, S., Shestakov, D., Бодунова, Н. А., & Gusev, O. (2025) · Genes · doi:10.3390/genes16080948 · Cited by 15

Measuring biological age: Insights from omics studies

Kočar, E., Šket, R., Vasle, A. H., Avguštin, G., Benedik, E., Seljak, B. K., Simić, P., Martinko, A., Morrison, S. A., Sorić, M., et al. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102988 · Cited by 23

rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts

Fuku, N., Díaz‐Peña, R., Arai, Y., Abe, Y., Pareja-Galeano, H., Sanchis‐Gomar, F., Santos‐Lozano, A., Zempo, H., Naıto, H., Murakami, H., et al. (2016) · Maturitas · doi:10.1016/j.maturitas.2016.07.016 · Cited by 14

Lead and Aquatic Ecosystems, Biomarkers, and Implications for Humankind

Sarkar, O., Dey, K. K., Islam, S., & Chattopadhyay, A. (2022) · Biomarkers in disease · doi:10.1007/978-3-030-87225-0_58-1 · Cited by 14

Macelignan inhibits the inflammatory response of microglia and regulates neuronal survival

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The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans

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