Amygdalar gray matter volume and social relating in schizophrenia
Abstract
BACKGROUND: Poor social relating is a prominent feature of schizophrenia. The amygdala has been suggested as an important node in social brain networks. METHODS: By using structural magnetic resonance imaging, this study examined, for the first time, the relationship between amygdalar gray matter (GM) volume and social relating in 35 schizophrenia patients. Social anhedonia, interaction anxiety, extraversion, and sociable tendencies were assessed as indices of social relating. RESULTS: A correlation between GM volume in the amygdala and enhanced social relating was revealed. CONCLUSION: These findings indicate that volumetric decreases in the amygdala are related to impoverished sociability in schizophrenia.
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Smaller amygdala volumes have been related to higher social anhedonia scores in patients with schizophrenia.
“smaller amygdala volumes have been related to higher social anhedonia scores in patients with schizophrenia (172).”
From A transdiagnostic perspective on social anhedonia (2019) · cites this paper as [172]
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A transdiagnostic perspective on social anhedonia
Barkus, E., & Badcock, J. C. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00216 · Cited by 165 · see citing works
- Authors
- Günther, V., Lindner, C., Dannlowski, U., Kugel, H., & Suslow, T.
- Affiliations
- Leipzig University (DE)
- Helios Kliniken (DE)
- University of Münster (DE)
- Venue
- Neuropsychobiology
- Publisher
- S. Karger AG
- Published
- 2016
- Volume
- 74
- Issue
- 3
- Pages
- 139-143
- ISSN
- 0302-282X (ISSN-L)
- 1423-0224
- OpenAlex
- W2610121456
- Cited by
- 8
- References
- 28
- Citations by year
- 2024: 1 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 2
- FWCI
- 0.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychobiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- schizophrenia, amygdala, gray matter volume, social anhedonia, interaction anxiety, sociability, social brain network, brain volumetry
- MeSH terms
- Adolescent, Adult, Amygdala, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Schizophrenia, Schizophrenic Psychology, Social Behavior, Young Adult, Gray Matter
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