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Methodological Recommendations for Trials of Psychological Interventions
Open accessAbstract
Recent years have seen major developments in psychotherapy research that suggest the need to address critical methodological issues. These recommendations, developed by an international group of researchers, do not replace those for randomized controlled trials, but rather supplement strategies that need to be taken into account when considering psychological treatments. The limitations of traditional taxonomy and assessment methods are outlined, with suggestions for consideration of staging methods. Active psychotherapy control groups are recommended, and adaptive and dismantling study designs offer important opportunities. The treatments that are used, and particularly their specific ingredients, need to be described in detail for both the experimental and the control groups. Assessment should be performed blind before and after treatment and at long-term follow-up. A combination of observer- and self-rated measures is recommended. Side effects of psychotherapy should be evaluated using appropriate methods. Finally, the number of participants who deteriorate after treatment should be noted according to the methods that were used to define response or remission.
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Metadata
- Authors
- Guidi, J., Brakemeier, E.-L., Bockting, C. L. H., Cosci, F., Cuijpers, P., Jarrett, R. B., Linden, M., Marks, I., Peretti, C. S., Rafanelli, C., Rief, W., Schneider, S., Schnyder, U., Sensky, T., Tomba, E., Vazquez, C., Vieta, E., Zipfel, S., Wright, J. H., & Fava, G. A.
- Affiliations
- University of Bologna (IT)
- Philipps University of Marburg (DE)
- University of Amsterdam (NL)
- University of Florence (IT)
- Vrije Universiteit Amsterdam (NL)
- The University of Texas Southwestern Medical Center (US)
- Charité – Universitätsmedizin Berlin (DE)
- King's College London (GB)
- Sorbonne Université (FR)
- Ruhr University Bochum (DE)
- University of Zurich (CH)
- Imperial College London (GB)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- University of Tübingen (DE)
- University of Louisville (US)
- University at Buffalo, State University of New York (US)
- ORCID
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2018
- Volume
- 87
- Issue
- 5
- Pages
- 276-284
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W2883850069
- Cited by
- 205
- References
- 61
- Citations by year
- 2026: 13 · 2025: 11 · 2024: 25 · 2023: 24 · 2022: 30 · 2021: 36 · 2020: 38 · 2019: 26 · 2018: 2
- FWCI
- 29.90
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychotherapy and Psychosomatics (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion, other-oa)
- VU Research Portal (publishedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
- Florence Research (University of Florence) (submittedVersion, other-oa)
- Dokumentenrepositorium der RUB (Ruhr University Bochum) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
- Florence Research (University of Florence) (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- psychological intervention, psychotherapy research methodology, treatment evaluation, treatment response and remission, long-term follow-up
- MeSH terms
- Mental Disorders, Humans, Psychotherapy, Research Design, Outcome Assessment, Health Care, Practice Guidelines as Topic, Biomedical Research
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