Cited by 20Spectroscopy Techniques in Biomedical and Chemical ResearchNon-Invasive Vital Sign MonitoringDiabetes Management and Research

Non-invasive glucose monitoring devices: A review

Open access
Mohamad Yunos, Muhammad Farhan Affendi, Nordin, Anis Nurashikin·2020·Bulletin of Electrical Engineering and Informatics

Abstract

Diabetes is a growing chronic disease that affect millions of people in the world. Regular monitoring of blood glucose levels in patients is necessary to keep the disease under control. Current methods of blood glucose monitoring devices are typically invasive, causing discomfort to the patients. Non-invasive glucose monitoring devices are a possible game changer for diabetic patients as it reduces discomfort and provides continuous monitoring. This manuscript presents a review of non-invasive glucose biosensors with particular focus on leading technologies available in the market, such as microwave sensing, near-infrared spectroscopy, iontophoresis, and optical methods. This paper intends to describe non-invasive blood glucose monitoring methods using various biological fluids (sweat, saliva, interstitial fluid, urine), highlighting the advantages and drawbacks in latest device development. This review also discusses future trends of glucose detection devices and how it will improve patients’ quality of life.

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Crossref · 10.11591/eei.v9i6.2628

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  • A correlation between sweat glucose and blood glucose exists, and obtaining blood glucose values by detecting glucose in sweat is expected to replace conventional diabetes blood glucose monitoring practices.

    “A correlation between sweat glucose and blood glucose exists and obtaining blood glucose values by detecting glucose in sweat is thus expected to replace conventional diabetes blood glucose monitoring practices 83,84”

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Research works printed but not linked: 3

  1. M. Jayakrishnan, S. Skaria, D. Sathyanath, and P. Mohanan, "RF assisted non invasive method for blood glucose monitoring- a feasiblity study," in 2015 IEEE Applied Electromagnetics Conference (AEMC), Guwahati, 2015, pp. 1-2.
  2. J. Yuan, Y. Cen, X.-J. Kong, S. Wu, C.-L. Liu, R.-Q. Yu, et al., "MnO2-nanosheet-modified upconversion nanosystem for sensitive turn-on fluorescence detection of H2O2 and glucose in blood," ACS applied materials & interfaces, vol. 7, no. 15, pp. 10548-10555, 2015.
  3. S. Kanjananimmanont, X. Ge, K. Mupparapu, G. Rao, R. Potts, and L. Tolosa, "Passive diffusion of transdermal glucose: noninvasive glucose sensing using a fluorescent glucose binding protein," Journal of diabetes science and technology, vol. 8, no. 2, pp. 291-298, 2014.

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Authors
Mohamad Yunos, M. F. A., & Nordin, A. N.
Affiliations
International Islamic University Malaysia (MY)
Venue
Bulletin of Electrical Engineering and Informatics
Published
2020-12-01
Volume
9
Issue
6
Pages
2609-2618
ISSN
  • 2089-3191 (ISSN-L)
  • 2302-9285
OpenAlex
W3032534361
Cited by
20
References
36
Citations by year
2026: 1 · 2025: 7 · 2024: 4 · 2023: 4 · 2022: 3 · 2021: 1
FWCI
0.95
Type
journal article
Language
en
Open access
Locations
  • Bulletin of Electrical Engineering and Informatics (publishedVersion)
  • The International Islamic University Malaysia Repository (The International Islamic University Malaysia) (acceptedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
non-invasive glucose monitoring, diabetes mellitus, microwave sensing, near-infrared spectroscopy, iontophoresis, optical glucose sensing, sweat, saliva, interstitial fluid, urine, continuous glucose monitoring

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