The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Pathological Mechanisms of Fatal Late Coronary Stent Thrombosis in Humans
Open accessAbstract
Background— Coronary stent deployment is associated with a low incidence of acute thrombosis. However, late stent thrombosis (LST) has likely been underrecognized clinically, and pathological descriptions are lacking. Methods and Results— LST was defined as an acute thrombus within a stent that had been in place ≥30 days. Cases of LST were selected from a registry of human coronary stents submitted for analysis. Thirteen cases of LST (9 men, 4 women) were identified. The mean duration from implantation to thrombosis was 3.6±3.5 months (range, 1 to 11.9 months). The causes of death were sudden cardiac death (n=10), acute myocardial infarction (n=2), and heart failure (n=1). The pathological mechanisms of LST were as follows: (1) stenting across ostia of major arterial branches (5 cases); (2) exposure to radiation therapy (3 cases); (3) plaque disruption in the nonstented arterial segment within 2 mm of the stent margin (2 cases); (4) stenting of markedly necrotic, lipid-rich plaques with extensive plaque prolapse (2 cases); and (5) diffuse in-stent restenosis (1 case). Twelve cases demonstrated a failure to form a completely healed neointimal layer overlying stent struts. Underlying in-stent restenosis was present in only 4 (31%) of 13 cases. Conclusions— LST is a potentially fatal complication of coronary stenting. Stenting across branch ostia, disruption of adjacent vulnerable plaques, radiation therapy, and extensive plaque prolapse can precipitate LST. Impaired intimal healing (ie, the failure to form a complete neointimal layer over stent struts) extends the window during which stents are prone to thrombosis.
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Cites
Compensatory Enlargement of Human Atherosclerotic Coronary Arteries
Glagov, S., Weisenberg, E., Zarins, C. K., Stankunavicius, R., & Kolettis, G. J. (1987) · New England Journal of Medicine · doi:10.1056/nejm198705283162204 · Cited by 3,623
Coronary Risk Factors and Plaque Morphology in Men with Coronary Disease Who Died Suddenly
Burke, A. P., Farb, A., Malcom, G. T., Liang, Y.-H., Smialek, J., & Virmani, R. (1997) · New England Journal of Medicine · doi:10.1056/nejm199705013361802 · Cited by 1,745
Self-citationHemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries.
Glagov, S., Zarins, C. K., Giddens, D. P., & Ku, D. N. (1988) · PubMed · Cited by 1,029
Pathology of Acute and Chronic Coronary Stenting in Humans
Farb, A., Sangiorgi, G., Carter, A. J., Walley, V. M., Edwards, W. D., Schwartz, R. S., & Virmani, R. (1999) · Circulation · doi:10.1161/01.cir.99.1.44 · Cited by 871
Self-citationStent Thrombosis in the Modern Era: A Pooled Analysis of Multicenter Coronary Stent Clinical Trials
Cutlip, D. E., Baim, D. S., Ho, K. K. L., Popma, J. J., Lansky, A. J., Cohen, D. J., Carrozza, J. P., Chauhan, M. S., Rodriguez, O., & Kuntz, R. E. (2001) · Circulation · doi:10.1161/01.cir.103.15.1967 · Cited by 855
Morphological Predictors of Restenosis After Coronary Stenting in Humans
Farb, A., Weber, D. K., Kolodgie, F. D., Burke, A. P., & Virmani, R. (2002) · Circulation · doi:10.1161/01.cir.0000019071.72887.bd · Cited by 593
Self-citationGrewe, P. H., Deneke, T., Machraoui, A., Barmeyer, J., & Müller, K.-M. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00486-6 · Cited by 401
Late Coronary Occlusion After Intracoronary Brachytherapy
Costa, M. A., Sabaté, M., van der Giessen, W. J., Kay, I. P., Cervinka, P., Ligthart, J. M. R., Serrano, P., Coen, V. L. M. A., Levendag, P. C., & Serruys, P. W. (1999) · Circulation · doi:10.1161/01.cir.100.8.789 · Cited by 389
Carter, A. J., Laird, J. R., Farb, A., Kufs, W., Wortham, D. C., & Virmani, R. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90126-0 · Cited by 229
Self-citationLate Thrombosis After Radiation: Sitting on a Time Bomb
Waksman, R. (1999) · Circulation · doi:10.1161/01.cir.100.8.780 · Cited by 175
Cited by
Pathology of Drug-Eluting Stents in Humans
Joner, M., Finn, A. V., Farb, A., Mont, E. K., Kolodgie, F. D., Ladich, E., Kutys, R., Skorija, K., Gold, H. K., & Virmani, R. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.03.042 · Cited by 2,744
Self-citationStewart, F. A., Akleyev, A. V., Hauer-Jensen, M., Hendry, J. H., Kleiman, N. J., MacVittie, T. J., Aleman, B. M., Edgar, A. B., Mabuchi, K., Muirhead, C. R., et al. (2012) · Annals of the ICRP · doi:10.1016/j.icrp.2012.02.001 · Cited by 1,604
Metadata
- Authors
- Farb, A., Burke, A. P., Kolodgie, F. D., & Virmani, R.
- Venue
- Circulation
- Published
- 2003-10-07
- Volume
- 108
- Issue
- 14
- Pages
- 1701-1706
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2164466909
- Cited by
- 478
- References
- 14
- FWCI
- 19.43
- Type
- journal article
- Language
- en
- Open access
- bronze
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