The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Hypertrophy of the Heart: A New Therapeutic Target?
Open accessAbstract
Recent studies call into question the necessity of hypertrophic growth of the heart as a “compensatory” response to hemodynamic stress. These findings, coupled with recent progress in dissecting the molecular bases of hypertrophy, raise the prospect of suppressing hypertrophy without provoking circulatory insufficiency. In this article, we focus on signaling pathways that hold promise as potential targets for therapeutic intervention. We also summarize observations from animal models and clinical trials that suggest benefit from an antihypertrophic strategy.
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Cites
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Self-citationdel Monte, F., Williams, E., Lebeche, D., Schmidt, U., Rosenzweig, A., Gwathmey, J. K., Lewandowski, E. D., & Hajjar, R. J. (2001) · Circulation · doi:10.1161/hc3601.095574 · Cited by 382
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Self-citation
Cited by
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
Hamanaka, R. B., & Chandel, N. S. (2010) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2010.04.002 · Cited by 1,011
Molecular basis of physiological heart growth: fundamental concepts and new players
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Targeting mammalian target of rapamycin (mTOR) for health and diseases
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Metadata
- Authors
- Frey, N., Katus, H. A., Olson, E. N., & Hill, J. A.
- Venue
- Circulation
- Published
- 2004-04-06
- Volume
- 109
- Issue
- 13
- Pages
- 1580-1589
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2041043528
- Cited by
- 851
- References
- 10
- FWCI
- 21.07
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Frey, N., Katus, H. A., Olson, E. N., & Hill, J. A. (2004). Hypertrophy of the Heart: A New Therapeutic Target? Circulation. https://doi.org/10.1161/01.cir.0000120390.68287.bb
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
