The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Fractional Flow Reserve in Patients With Prior Myocardial Infarction
Open accessAbstract
Background — Fractional flow reserve (FFR), an index of coronary stenosis severity, can be calculated from the ratio of hyperemic distal to proximal coronary pressure. An FFR value of 0.75 can distinguish patients with normal and abnormal noninvasive stress testing in case of normal left ventricular function. The present study aimed at investigating the value of FFR in patients with a prior myocardial infarction. Methods and Results — In 57 patients who had sustained a myocardial infarction ≥6 days earlier, myocardial perfusion single photon emission scintigraphy (SPECT) imaging and FFR were obtained before and after angioplasty. The sensitivity and specificity of the 0.75 value of FFR to detect flow maldistribution at SPECT imaging were 82% and 87%. The concordance between the FFR and SPECT imaging was 85% ( P <0.001). When only truly positive and truly negative SPECT imaging were considered, the corresponding values were 87%, 100%, and 94% ( P <0.001). Patients with positive SPECT imaging before angioplasty had a significantly lower FFR than patients with negative SPECT imaging (0.52±0.18 versus 0.67±0.16, P =0.0079) but a significantly higher left ventricular ejection fraction (63±10% versus 52±10%, P =0.0009) despite a similar degree of diameter stenosis (67±13% versus 68±16%, P =NS). A significant inverse correlation was found between LVEF and FFR ( R =0.29, P =0.049). Conclusions — The present data indicate (1) that the 0.75 cutoff value of FFR to distinguish patients with positive from patients with negative SPECT imaging is valid after a myocardial infarction and (2) that for a similar degree of stenosis, the value of FFR depends on the mass of viable myocardium.
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Measurement of Fractional Flow Reserve to Assess the Functional Severity of Coronary-Artery Stenoses
Pijls, N. H. J., de Bruyne, B., Peels, K., van der Voort, P. H., Bonnier, H. J. R. M., Bartunek, J., & Koolen, J. J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199606273342604 · Cited by 2,321
Self-citationPijls, N. H., van Son, J. A., Kirkeeide, R. L., De Bruyne, B., & Gould, K. L. (1993) · Circulation · doi:10.1161/01.cir.87.4.1354 · Cited by 1,183
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Self-citationEffects of adenosine on human coronary arterial circulation.
Wilson, R. F., Wyche, K., Christensen, B. V., Zimmer, S., & Laxson, D. D. (1990) · Circulation · doi:10.1161/01.cir.82.5.1595 · Cited by 906
Reiber, J. H., Serruys, P. W., Kooijman, C. J., Wijns, W., Slager, C. J., Gerbrands, J. J., Schuurbiers, J. C., den Boer, A., & Hugenholtz, P. G. (1985) · Circulation · doi:10.1161/01.cir.71.2.280 · Cited by 829
Self-citationPedersen, O. D., Bagger, H., Køber, L., & Torp-Pedersen, C. (1999) · Circulation · doi:10.1161/01.cir.100.4.376 · Cited by 656
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Self-citationReduced Coronary Vasodilator Function in Infarcted and Normal Myocardium after Myocardial Infarction
Uren, N. G., Crake, T., Lefroy, D. C., de Silva, R., Davies, G. J., & Maseri, A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199407283310402 · Cited by 391
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2023 ESC Guidelines for the management of acute coronary syndromes
Byrne, R. A., Rossello, X., Coughlan, J. J., Barbato, E., Berry, C., Chieffo, A., Claeys, M. J., Dan, G.-A., Dweck, M. R., Galbraith, M., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad191 · Cited by 5,333
Percutaneous Coronary Intervention of Functionally Nonsignificant Stenosis
Pijls, N. H. J., van Schaardenburgh, P., Manoharan, G., Boersma, E., Bech, J.-W., van’t Veer, M., Bär, F., Hoorntje, J., Koolen, J., Wijns, W., et al. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.01.087 · Cited by 1,516
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Metadata
- Authors
- De Bruyne, B., Pijls, N. H. J., Bartunek, J., Kulecki, K., Bech, J.-W., De Winter, H., Van Crombrugge, P., Heyndrickx, G. R., & Wijns, W.
- Venue
- Circulation
- Published
- 2001-07-10
- Volume
- 104
- Issue
- 2
- Pages
- 157-162
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2032468742
- Cited by
- 386
- References
- 17
- FWCI
- 10.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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- De Bruyne, B., Pijls, N. H. J., Bartunek, J., Kulecki, K., Bech, J.-W., De Winter, H., Van Crombrugge, P., Heyndrickx, G. R., & Wijns, W. (2001). Fractional Flow Reserve in Patients With Prior Myocardial Infarction. Circulation. https://doi.org/10.1161/01.cir.104.2.157
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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