The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Coronary Heart Disease and Iron Status: Meta-Analyses of Prospective Studies
Abstract
BACKGROUND: Studies of iron status and coronary heart disease (CHD) have yielded conflicting results. In a systematic review ("meta-analysis"), we quantitatively assessed epidemiological associations reported in prospective studies. METHODS AND RESULTS: Studies were identified by computer-assisted searches of the published literature, scanning of relevant reference lists, hand searching of relevant journals, and discussions with relevant authors. The following was abstracted: size and type of cohort, mean age, mean duration of follow-up, assay methods, degree of adjustment for confounders, and relationship of CHD risk to the baseline assay results. Twelve studies were identified, involving a total of 7800 CHD cases, with several reporting on >1 marker of iron status. For serum ferritin, with 570 CHD cases in 5 studies, comparison of individuals with baseline values >/=200 versus <200 microg/L yielded a combined risk ratio of 1.0 (95% CI, 0.8 to 1.3). For transferrin saturation, with 6194 CHD cases in 5 studies, comparison of individuals in the top third with those in the bottom third of the baseline measurements yielded a combined risk ratio of 0.9 (95% CI, 0.7 to 1.1). Comparisons of individuals in top and bottom thirds of baseline measurements also yielded nonsignificant risk ratios in combined analyses of studies involving total iron-binding capacity (combined risk ratio, 1.0; 95% CI, 0.7 to 1.5), serum iron (0.8; 95% CI, 0.7 to 1.0), and total dietary iron (0.8; 95% CI, 0.7 to 1.1). CONCLUSIONS: Published prospective studies do not provide good evidence to support the existence of strong epidemiological associations between iron status and CHD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Several randomised controlled intervention trials have shown that supplementation with different quantities of soya protein did not affect markers of inflammation (CRP, IL-6, IL-18, sICAM-1, sVCAM-1 and sE-selectin) (Table 7) (345,347 -364) .”
From Dietary factors and low-grade inflammation in relation to overweight and obesity (2011) · cites this paper as [347]
Citations
Cites
Publication bias in clinical research
Easterbrook, P. J., Gopalan, R., Berlin, J. A., & Matthews, D. R. (1991) · The Lancet · doi:10.1016/0140-6736(91)90201-y · Cited by 3,109
Danesh, J., Collins, R., Appleby, P. N., & Peto, R. (1998) · JAMA · doi:10.1001/jama.279.18.1477 · Cited by 2,027
Self-citationA Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians
Stampfer, M. J. (1992) · JAMA · doi:10.1001/jama.1992.03490070059042 · Cited by 1,705
Salonen, J. T., Nyyssönen, K., Korpela, H., Tuomilehto, J., Seppänen, R., & Salonen, R. (1992) · Circulation · doi:10.1161/01.cir.86.3.803 · Cited by 1,284
Dietary iron intake and risk of coronary disease among men.
Ascherio, A., Willett, W. C., Rimm, E. B., Giovannucci, E. L., & Stampfer, M. J. (1994) · Circulation · doi:10.1161/01.cir.89.3.969 · Cited by 286
Body Iron Stores and the Risk of Coronary Heart Disease
Sempos, C. T., Looker, A. C., Gillum, R. F., & Makuc, D. M. (1994) · New England Journal of Medicine · doi:10.1056/nejm199404213301604 · Cited by 251
Low iron-binding capacity as a risk factor for myocardial infarction.
Magnússon, M. K., Sigfússon, N., Sigvaldason, H., Jóhannesson, G. M., Magnússon, S. H., & Thorgeirsson, G. (1994) · Circulation · doi:10.1161/01.cir.89.1.102 · Cited by 181
Serum Iron and Risk of Fatal Acute Myocardial Infarction
MORRISON, H. I., Semenciw, R. M., Mao, Y., & Wigle, D. T. (1994) · Epidemiology · doi:10.1097/00001648-199403000-00015 · Cited by 146
Serum ferritin and ceruloplasmin as coronary risk factors
Mänttäri, M., Manninen, V., HURRUNEN, J. K., Palosuo, T., Ehnholm, C., Heinonen, O. P., & Frick, M. H. (1994) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a060440 · Cited by 144
Cited by
Sorted by citations
Guidelines on food fortification with micronutrients
Allen, L. H. (2006) · Cited by 1,562
Whitfield, J. B. (2001) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/20014091084227 · Cited by 1,158
Dietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098
Evidence-Based Guidelines for Cardiovascular Disease Prevention in Women
Mosca, L. J., Appel, L. J., Benjamin, E. J., Berra, K. A., Chandra‐Strobos, N., Fabunmi, R. P., Grady, D. G., Haan, C. K., Hayes, S. N., Judelson, D. R., et al. (2004) · Circulation · doi:10.1161/01.cir.0000114834.85476.81 · Cited by 918
Bioavailability of iron, zinc, and other trace minerals from vegetarian diets
Hunt, J. R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.3.633s · Cited by 637
Metadata
- Authors
- Danesh, J., & Appleby, P.
- Affiliations
- University of Oxford (GB)
- ORCID
- Danesh, John
- Venue
- Circulation
- Published
- 1999-02-23
- Volume
- 99
- Issue
- 7
- Pages
- 852-854
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2072848251
- Cited by
- 226
- References
- 19
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 1 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 5 · 2014: 9 · 2013: 10 · 2012: 12
- FWCI
- 7.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Keywords
- coronary artery disease, iron status, serum ferritin, transferrin saturation, total iron binding capacity, serum iron, dietary iron, cardiovascular risk factors, prospective cohort
- MeSH terms
- Coronary Disease, Diet, Ferritins, Humans, Iron, Prospective Studies, Transferrin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
